Intranasal administration of oxytocin modulates behavioral and amygdala responses to infant crying in females with insecure attachment representations

References

• Ainsworth, M.D., Blehar, M., Waters, E., & Wall, S. (1978). Patterns of attachment. Hillsdale, NJ: Erlbaum.
   Google Scholar
• Bakermans-Kranenburg, M.J., & van IJzendoorn, M.H. (2013). Sniffing around oxytocin: Review and meta-analyses of trials in healthy and clinical groups with implications for pharmacotherapy. Translational Psychiatry, 3, e258. doi:10.1038/tp.2013.34
   PubMed Web of Science ®Google Scholar
• Bakermans-Kranenburg, M.J., van IJzendoorn, M.H., Riem, M.M.E., Tops, M., & Alink, L.R. (2012). Oxytocin decreases handgrip force in reaction to infant crying in females without harsh parenting experiences. Social Cognitive and Affective Neuroscience, 7(8), 951–957. doi:10.1093/scan/nsr067
   PubMed Web of Science ®Google Scholar
• Bartz, J.A., Zaki, J., Bolger, N., & Ochsner, K.N. (2011). Social effects of oxytocin in humans: Context and person matter. Trends in Cognitive Sciences, 15(7), 301–309.
   PubMed Web of Science ®Google Scholar
• Bartz, J.A., Zaki, J., Ochsner, K.N., Bolger, N., Kolevzon, A., Ludwig, N., & Lydon, J.E. (2010). Effects of oxytocin on recollections of maternal care and closeness. Proceedings of the National Academy of Sciences of the United States of America, 107(50), 21371–21375. doi:10.1073/pnas.1012669107
   PubMed Web of Science ®Google Scholar
• Buchheim, A., Heinrichs, M., George, C., Pokorny, D., Koops, E., Henningsen, P., … Gündel, H. (2009). Oxytocin enhances the experience of attachment security. Psychoneuroendocrinology, 34(9), 1417–1422. doi:10.1016/j.psyneuen.2009.04.002
   PubMed Web of Science ®Google Scholar
• Bugental, D.B., Lewis, J.C., Lin, E., Lyon, J., & Kopeikin, H. (1999). In charge but not in control: The management of teaching relationships by adults with low perceived power. Developmental Psychology, 35(6), 1367–1378. doi:10.1037/0012-1649.35.6.1367
   PubMed Web of Science ®Google Scholar
• Carter, C.S. (1998). Neuroendocrine perspectives on social attachment and love. Psychoneuroendocrinology, 23(8), 779–818. doi:10.1016/S0306-4530(98)00055-9
   PubMed Web of Science ®Google Scholar
• Casanova, G.M., Domanic, J., McCanne, T.R., & Milner, J.S. (1994). Physiological responses to child stimuli in mothers with and without a childhood history of physical abuse. Child Abuse & Neglect, 18(12), 995–1004. doi:10.1016/0145-2134(94)90124-4
   PubMed Web of Science ®Google Scholar
• Clark-Elford, R., Nathan, P.J., Auyeung, B., Mogg, K., Bradley, B.P., Sule, A., … Baron-Cohen, S. (2014). Effects of oxytocin on attention to emotional faces in healthy volunteers and highly socially anxious males. International Journal of Neuropsychopharmacology, 18, pyu012.
   PubMed Web of Science ®Google Scholar
• Compier-de Block, L.H.C.G., Alink, L.R.A., Reijman, S., Werner, C.D., Maras, A., Rijnberk, C., … Bakermans-Kranenburg, M.J. (2015). Handgrip force of maltreating mothers in reaction to infant signals. Child Abuse & Neglect, 40, 124–131. doi:10.1016/j.chiabu.2014.03.006
   PubMed Web of Science ®Google Scholar
• Crittenden, P.M. (2004). Patterns of attachment in adulthood: A dynamic-maturational approach to analyzing. The Adult Attachment Interview. Unpublished manuscript.
   Google Scholar
• Crouch, J.L., Skowronski, J.J., Milner, J.S., & Harris, B. (2008). Parental responses to infant crying: The influence of child physical abuse risk and hostile priming. Child Abuse & Neglect, 32(7), 702–710. doi:10.1016/j.chiabu.2007.11.002
   PubMed Web of Science ®Google Scholar
• David, S.P., Ware, J.J., Chu, I.M., Loftus, P.D., Fusar-Poli, P., Radua, J., … Kilner, J. (2013). Potential reporting bias in fMRI studies of the brain. PLoS One, 8(7), e70104. doi:10.1371/journal.pone.0070104
   PubMed Web of Science ®Google Scholar
• De Dreu, C.K.W. (2012). Oxytocin modulates the link between adult attachment and cooperation through reduced betrayal aversion. Psychoneuroendocrinology, 37(7), 871–880. doi:10.1016/j.psyneuen.2011.10.003
   PubMed Web of Science ®Google Scholar
• De Dreu, C.K.W., Greer, L.L., Handgraaf, M.J., Shalvi, S., Van Kleef, G.A., Baas, M., … Feith, S.W.W. (2010). The neuropeptide oxytocin regulates parochial altruism in intergroup conflict among humans. Science, 328(5984), 1408–1411. doi:10.1126/science.1189047
   PubMed Web of Science ®Google Scholar
• Declerck, C.H., Boone, C., & Kiyonari, T. (2010). Oxytocin and cooperation under conditions of uncertainty: The modulating role of incentives and social information. Hormones and Behavior, 57(3), 368–374. doi:10.1016/j.yhbeh.2010.01.006
   PubMed Web of Science ®Google Scholar
• Dessureau, B.K., Kurowski, C.O., & Thompson, N.S. (1998). A reassessment of the role of pitch and duration in adults’ responses to infant crying. Infant Behavior & Development, 21(2), 367–371. doi:10.1016/S0163-6383(98)90013-3
   Web of Science ®Google Scholar
• Domes, G., Heinrichs, M., Gläscher, J., Büchel, C., Braus, D.F., & Herpertz, S.C. (2007). Oxytocin attenuates amygdala responses to emotional faces regardless of valence. Biological Psychiatry, 62(10), 1187–1190. doi:10.1016/j.biopsych.2007.03.025
   PubMed Web of Science ®Google Scholar
• Dykas, M.J., & Cassidy, J. (2011). Attachment and the processing of social information across the life span: Theory and evidence. Psychological Bulletin, 137(1), 19–46. doi:10.1037/a0021367
   PubMed Web of Science ®Google Scholar
• Egeland, B., Jacobvitz, D., & Sroufe, A.L. (1988). Breaking the cycle of abuse. Child Development, 59, 1080–1088. doi:10.2307/1130274
   PubMed Web of Science ®Google Scholar
• Fan, Y., Pestke, K., Feeser, M., Aust, S., Pruessner, J.C., Böker, H., … Grimm, S. (2015). Amygdala-hippocampal connectivity changes during acute psychosocial stress: Joint effect of early life stress and oxytocin. Neuropsychopharmacology, 40, 2736–2744. doi:10.1038/npp.2015.123
   PubMed Web of Science ®Google Scholar
• Feldman, R., Gordon, I., Schneiderman, I., Weisman, O., & Zagoory-Sharon, O. (2010). Natural variations in maternal and paternal care are associated with systematic changes in oxytocin following parent-infant contact. Psychoneuroendocrinology, 35(8), 1133–1141. doi:10.1016/j.psyneuen.2010.01.013
   PubMed Web of Science ®Google Scholar
• Feldman, R., Weller, A., Zagoory-Sharon, O., & Levine, A. (2007). Evidence for a neuroendocrinological foundation of human affiliation: Plasma oxytocin levels across pregnancy and the postpartum period predict mother-infant bonding. Psychological Science, 18(11), 965–970. doi:10.1111/j.1467-9280.2007.02010.x
   PubMed Web of Science ®Google Scholar
• Galbally, M., Lewis, A.J., van IJzendoorn, M.H., & Permezel, M. (2011). The role of oxytocin in mother-infant relations: A systematic review of human studies. Harvard Review of Psychiatry, 19(1), 1–14. doi:10.3109/10673229.2011.549771
   PubMed Web of Science ®Google Scholar
• George, C., Kaplan, N., & Main, M. (1985). Adult attachment interview. Unpublished manuscript.
   Google Scholar
• Grimm, S., Pestke, K., Feeser, M., Aust, S., Weigand, A., Wang, J., … Bajbouj, M. (2014). Early life stress modulates oxytocin effects on limbic system during acute psychosocial stress. Social Cognitive and Affective Neuroscience, 9(11), 1828–1835. doi:10.1093/scan/nsu020
   PubMed Web of Science ®Google Scholar
• Groh, A.M., & Roisman, G.I. (2009). Adults’ autonomic and subjective emotional responses to infant vocalizations: The role of secure base script knowledge. Developmental Psychology, 45(3), 889–893. doi:10.1037/a0014943
   PubMed Web of Science ®Google Scholar
• Heinrichs, M., Von Dawans, B., & Domes, G. (2009). Oxytocin, vasopressin, and human social behavior. Frontiers in Neuroendocrinology, 30(4), 548–557. doi:10.1016/j.yfrne.2009.05.005
   PubMed Web of Science ®Google Scholar
• Hesse, E. (2008). The Adult Attachment Interview: Protocol, method of analysis, and empirical studies. In J. Cassidy & P. R. Shaver (Eds.), Handbook of attachment: Theory, research, and clinical applications (2nd ed., pp. 552–598). New York, NY: Guilford.
   Google Scholar
• Insel, T.R. (2010). The challenge of translation in social neuroscience: A review of oxytocin, vasopressin, and affiliative behavior. Neuron, 65(6), 768–779. doi:10.1016/j.neuron.2010.03.005
   PubMed Web of Science ®Google Scholar
• Ioannidis, J.P., Munafo, M.R., Fusar-Poli, P., Nosek, B.A., & David, S.P. (2014). Publication and other reporting biases in cognitive sciences: Detection, prevalence, and prevention. Trends in Cognitive Sciences, 18(5), 235–241. doi:10.1016/j.tics.2014.02.010
   PubMed Web of Science ®Google Scholar
• Jenkinson, M., Bannister, P., Brady, M., & Smith, S. (2002). Improved optimization for the robust and accurate linear registration and motion correction of brain images. Neuroimage, 17(2), 825–841. doi:10.1006/nimg.2002.1132
   PubMed Web of Science ®Google Scholar
• Jenkinson, M., & Smith, S. (2001). A global optimisation method for robust affine registration of brain images. Medical Image Analysis, 5(2), 143–156. doi:10.1016/S1361-8415(01)00036-6
   PubMed Web of Science ®Google Scholar
• Kirsch, P., Esslinger, C., Chen, Q., Mier, D., Lis, S., Siddhanti, S., … Meyer-Lindenberg, A. (2005). Oxytocin modulates neural circuitry for social cognition and fear in humans. Journal of Neuroscience, 25(49), 11489–11493. doi:10.1523/JNEUROSCI.3984-05.2005
   PubMed Web of Science ®Google Scholar
• LeDoux, J.E. (2000). Emotion circuits in the brain. Annual Review of Neuroscience, 23, 155–184. doi:10.1146/annurev.neuro.23.1.155
   PubMed Web of Science ®Google Scholar
• Leerkes, E.M. (2010). Predictors of maternal sensitivity to infant distress. Parenting: Science and Practice, 10(3), 219–239. doi:10.1080/15295190903290840
   PubMed Web of Science ®Google Scholar
• Leerkes, E.M., Parade, S.H., & Gudmundson, J.A. (2011). Mothers’ emotional reactions to crying pose risk for subsequent attachment insecurity. Journal of Family Psychology, 25(5), 635–643. doi:10.1037/a0023654
   PubMed Web of Science ®Google Scholar
• Leerkes, E.M., & Siepak, K.J. (2006). Attachment linked predictors of women’s emotional and cognitive responses to infant distress. Attachment & Human Development, 8(1), 11–32. doi:10.1080/14616730600594450
   PubMed Web of Science ®Google Scholar
• Leon, K., Jacobvitz, D.B., & Hazen, N.L. (2004). Maternal resolution of loss and abuse: Associations with adjustment to the transition to parenthood. Infant Mental Health Journal, 25, 130–148. doi:10.1002/(ISSN)1097-0355
   Web of Science ®Google Scholar
• Luminet, O., Grynberg, D., Ruzette, N., & Mikolajczak, M. (2011). Personality-dependent effects of oxytocin: Greater social benefits for high alexithymia scorers. Biological Psychology, 87(3), 401–406. doi:10.1016/j.biopsycho.2011.05.005
   PubMed Web of Science ®Google Scholar
• Ma, Y., Liu, Y., Rand, D.G., Heatherton, T.F., & Han, S. (2015). Opposing oxytocin effects on inter-group cooperative behavior in intuitive and reflective minds. Neuropsychopharmacology, 40, 2379–2387.
   Web of Science ®Google Scholar
• MacDonald, K., & MacDonald, T.M. (2010). The peptide that binds: A systematic review of oxytocin and its prosocial effects in humans. Harvard Review of Psychiatry, 18(1), 1–21. doi:10.3109/10673220903523615
   PubMed Web of Science ®Google Scholar
• Mah, B.L., Bakermans-Kranenburg, M.J., van IJzendoorn, M.H., & Smith, R. (2015). Oxytocin promotes protective behavior in depressed mothers: A pilot study with the enthusiastic stranger paradigm. Depression and Anxiety, 32(2), 76–81. doi:10.1002/da.2015.32.issue-2
   PubMed Web of Science ®Google Scholar
• Main, M., & Goldwyn, R. (1984). Adult attachment scoring and classification system. Unpublished manuscript.
   Google Scholar
• Main, M., Kaplan, N., & Cassidy, J. (1985). Security in infancy, childhood and adulthood: A move to the level of representation. In I. Bretherton & E. Waters (Eds). Growing points in attachment theory and research. Monographs of the Society for Research in Child Development, 50(1/2), 66–106. doi:10.2307/3333827
   Web of Science ®Google Scholar
• Meinlschmidt, G., & Heim, C. (2007). Sensitivity to intranasal oxytocin in adult men with early parental separation. Biological Psychiatry, 61(9), 1109–1111. doi:10.1016/j.biopsych.2006.09.007
   PubMed Web of Science ®Google Scholar
• Mikolajczak, M., Gross, J.J., Lane, A., Corneille, O., de Timary, P., & Luminet, O. (2010). Oxytocin makes people trusting, not gullible. Psychological Science, 21(8), 1072–1074. doi:10.1177/0956797610377343
   PubMed Web of Science ®Google Scholar
• Naber, F., Poslawsky, I.E., van IJzendoorn, M.H., Van Engeland, H., & Bakermans-Kranenburg, M.J. (2012). Brief report: Oxytocin enhances paternal sensitivity to a child with autism: A double-blind within-subject experiment with intranasally administered oxytocin. Journal of Autism and Developmental Disorders, 43, 1–6.
   PubMed Web of Science ®Google Scholar
• Naber, F., van IJzendoorn, M.H., Deschamps, P., Van Engeland, H., & Bakermans-Kranenburg, M.J. (2010). Intranasal oxytocin increases fathers’ observed responsiveness during play with their children: A double-blind within-subject experiment. Psychoneuroendocrinology, 35(10), 1583–1586. doi:10.1016/j.psyneuen.2010.04.007
   PubMed Web of Science ®Google Scholar
• Out, D., Pieper, S., Bakermans-Kranenburg, M.J., & van IJzendoorn, M.H. (2010). Physiological reactivity to infant crying: A behavioral genetic study. Genes Brain and Behavior, 9(8), 868–876. doi:10.1111/gbb.2010.9.issue-8
   PubMed Web of Science ®Google Scholar
• Out, D., Pieper, S., Bakermans-Kranenburg, M.J., Zeskind, P.S., & van IJzendoorn, M.H. (2010). Intended sensitive and harsh caregiving responses to infant crying: The role of cry pitch and perceived urgency in an adult twin sample. Child Abuse & Neglect, 34(11), 863–873. doi:10.1016/j.chiabu.2010.05.003
   PubMed Web of Science ®Google Scholar
• Petrovic, P., Kalisch, R., Singer, T., & Dolan, R.J. (2008). Oxytocin attenuates affective evaluations of conditioned faces and amygdala activity. Journal of Neuroscience, 28(26), 6607–6615. doi:10.1523/JNEUROSCI.4572-07.2008
   PubMed Web of Science ®Google Scholar
• Pierrehumbert, B., Torrisi, R., Ansermet, F., Borghini, A., & Halfon, O. (2012). Adult attachment representations predict cortisol and oxytocin responses to stress. Attachment & Human Development, 14(5), 453–476. doi:10.1080/14616734.2012.706394
   PubMed Web of Science ®Google Scholar
• Reijneveld, S.A., Van der Wal, M.F., Brugman, E., Sing, R.A., & Verloove-Vanhorick, S.P. (2004). Infant crying and abuse. Lancet, 364(9442), 1340–1342. doi:10.1016/S0140-6736(04)17191-2
   PubMed Web of Science ®Google Scholar
• Riem, M.M., Bakermans-Kranenburg, M.J., Huffmeijer, R., & van IJzendoorn, M.H. (2013). Does intranasal oxytocin promote prosocial behavior to an excluded fellow player? A randomized-controlled trial with Cyberball. Psychoneuroendocrinology, 38(8), 1418–1425. doi:10.1016/j.psyneuen.2012.12.023
   PubMed Web of Science ®Google Scholar
• Riem, M.M., Voorthuis, A., Bakermans-Kranenburg, M.J., & van IJzendoorn, M.H. (2014). Pity or peanuts? Oxytocin induces different neural responses to the same infant crying labeled as sick or bored. Developmenta Science, 17(2), 248–256.
   Google Scholar
• Riem, M.M.E., Bakermans-Kranenburg, M.J., Pieper, S., Tops, M., Boksem, M.A.S., Vermeiren, R.R.J.M., … Rombouts, S.A.R.B. (2011). Oxytocin modulates amygdala, insula, and inferior frontal gyrus responses to infant crying: A randomized controlled trial. Biological Psychiatry, 70(3), 291–297. doi:10.1016/j.biopsych.2011.02.006
   PubMed Web of Science ®Google Scholar
• Riem, M.M.E., Bakermans-Kranenburg, M.J., van IJzendoorn, M.H., Out, D., & Rombouts, S.A.R.B. (2012). Attachment in the brain: Adult attachment representations predict amygdala and behavioral responses to infant crying. Attachment & Human Development, 14(6), 533–551. doi:10.1080/14616734.2012.727252
   PubMed Web of Science ®Google Scholar
• Riem, M.M.E., Pieper, S., Out, D., Bakermans-Kranenburg, M.J., & van IJzendoorn, M.H. (2010). Oxytocin receptor gene and depressive symptoms associated with physiological reactivity to infant crying. Social Cognitive and Affective Neuroscience, 6, 294–300.
   PubMed Web of Science ®Google Scholar
• Riem, M.M.E., van IJzendoorn, M.H., Tops, M., Boksem, M.A., Rombouts, S.A., & Bakermans-Kranenburg, M.J. (2013). Oxytocin effects on complex brain networks are moderated by experiences of maternal love withdrawal. European Neuropsychopharmacology, 23(10), 1288–1295. doi:10.1016/j.euroneuro.2013.01.011
   PubMed Web of Science ®Google Scholar
• Rilling, J.K. (2013). The neural and hormonal bases of human parentalcare. Neuropsychologia, 51(4), 731–747. doi:10.1016/j.neuropsychologia.2012.12.017
   PubMed Web of Science ®Google Scholar
• Roisman, G.I., Haltigan, J.D., Haydon, K.C., & Booth‐LaForce, C. (2014). VI. Earned-Security in retrospect: Depressive symptoms, family stress, and maternal and paternal sensitivity from early childhood to mid-adolescence. Monographs of the Society for Research in Child Development, 79(3), 85–107. doi:10.1111/mono.12115
   PubMed Web of Science ®Google Scholar
• Roisman, G.I., Holland, A., Fortuna, K., Fraley, R.C., Clausell, E., & Clarke, A. (2007). The adult attachment interview and self-reports of attachment style: An empirical rapprochement. Journal of Personality and Social Psychology, 92(4), 678–697. doi:10.1037/0022-3514.92.4.678
   PubMed Web of Science ®Google Scholar
• Schoenmaker, C., Juffer, F., van IJzendoorn, M.H., Linting, M., Van Der Voort, A., & Bakermans-Kranenburg, M.J. (2015). From maternal sensitivity in infancy to adult attachment representations: A longitudinal adoption study with secure base scripts. Attachment & Human Development, 17, 241–256.
   PubMed Web of Science ®Google Scholar
• Schuetze, P., & Zeskind, P.S. (2001). Relations between women’s depressive symptoms and perceptions of infant distress signals varying in pitch. Infancy, 2(4), 483–499. doi:10.1207/S15327078IN0204_06
   PubMed Web of Science ®Google Scholar
• Schuetze, P., Zeskind, P.S., & Das Eiden, R. (2003). The perceptions of infant distress signals varying in pitch by cocaine-using mothers. Infancy, 4(1), 65–83. doi:10.1207/S15327078IN0401_4
   Web of Science ®Google Scholar
• Smith, S.M. (2002). Fast robust automated brain extraction. Human Brain Mapping, 17(3), 143–155. doi:10.1002/(ISSN)1097-0193
   PubMed Web of Science ®Google Scholar
• Smith, S.M., Jenkinson, M., Woolrich, M.W., Beckmann, C.F., Behrens, T.E.J., Johansen-Berg, H., … Matthews, P.M. (2004). Advances in functional and structural MR image analysis and implementation as FSL. Neuroimage, 23(Suppl 1), S208–S219. doi:10.1016/j.neuroimage.2004.07.051
   Web of Science ®Google Scholar
• Soltis, J. (2004). The signal functions of early infant crying. Behavioral and Brain Sciences, 27(4), 443–490.
   PubMed Web of Science ®Google Scholar
• Strathearn, L., Fonagy, P., Amico, J., & Montague, P.R. (2009). Adult attachment predicts maternal brain and oxytocin response to infant cues. Neuropsychopharmacology, 34(13), 2655–2666. doi:10.1038/npp.2009.103
   PubMed Web of Science ®Google Scholar
• Straus, M.A., Hamby, S.L., Finkelhor, D., Moore, D.W., & Runyan, D. (1998). Identification of child maltreatment with the parent-child conflict tactics scales: Development and psychometric data for a national sample of American parents (vol 22, pg 249, 1998). Child Abuse & Neglect, 22(4), 249–270. doi:10.1016/S0145-2134(97)00174-9
   PubMed Web of Science ®Google Scholar
• Swain, J.E., Kim, P., Spicer, J., Ho, S.S., Dayton, C.J., Elmadih, A., & Abel, K.M. (2014). Approaching the biology of human parental attachment: Brain imaging, oxytocin and coordinated assessments of mothers and fathers. Brain Research, 1580, 78–101. doi:10.1016/j.brainres.2014.03.007
   PubMed Web of Science ®Google Scholar
• Van IJzendoorn, M.H., & Bakermans-Kranenburg, M.J. (2014). Confined quest for continuity: The categorical versus continuous nature of attachment. Monographs of the Society for Research in Child Development, 79(3), 157–167.
   PubMed Web of Science ®Google Scholar
• Waters, E., Hamilton, C.E., & Weinfield, N.S. (2000). The stability of attachment security from infancy to adolescence and early adulthood: General introduction. Child Development, 71(3), 678–683. doi:10.1111/cdev.2000.71.issue-3
   PubMed Web of Science ®Google Scholar
• Weinfield, N.S., Sroufe, L.A., & Egeland, B. (2000). Attachment from infancy to early adulthood in a high-risk sample: Continuity, discontinuity, and their correlates. Child Development, 71(3), 695–702. doi:10.1111/cdev.2000.71.issue-3
   PubMed Web of Science ®Google Scholar
• Weisman, O., Delaherche, E., Rondeau, M., Chetouani, M., Cohen, D., & Feldman, R. (2013). Oxytocin shapes parental motion during father–infant interaction. Biology Letters, 9(6), 20130828. doi:10.1098/rsbl.2013.0828
   PubMed Web of Science ®Google Scholar
• Worsley, K.J. (2001). Statistical analysis of activation images. In P. Jezzard, P. M. Matthews, & S. M. Smith (Eds.), Functional MRI: An introduction to methods (pp. 251–270). New York, NY: Oxford University Press.
   Google Scholar
• Zeifman, D.M. (2001). An ethological analysis of human infant crying: Answering Tinbergen’s four questions. Developmental Psychobiology, 39(4), 265–285. doi:10.1002/(ISSN)1098-2302
   PubMed Web of Science ®Google Scholar