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International Journal of Cardiovascular Interventions Volume 3, 2000 - Issue 2
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Research Article

Ultrasound enhancement of thrombolytic therapy: observations and mechanisms

David Harpaz TheHeart Institute E Wolfson Medical Center Holon Sackler School of Medicine Tel-Aviv University Tel-Aviv, Israel
Pages 81-89 | Published online: 10 Jul 2009

  • Gruppo Italiano Per Lo Studio Delia Streptochinasi Nell' lnfarto Miocardico (GISSI): effectiveness of intravenous thrombolytic treatment in acute myocardial infarction. Lancet 1986; 1: 397-402.
  • ISIS-2 (Second International Study of lnfarct Survival) Collaborative Group: randomized trial of intravenous streptokinase, oral aspirin, both, or neither among 17 187 cases of suspected acute myocardial infarction: ISIS 2. Lancet 1988; 2: 349-360.
  • O'Rourke M, Daron D, Keogh A et al. Limitation of myocardial infarction by early infusion of recombinant tissue-type plasminogen activator. Circulation 1988; 77: 1311-1315.
  • Armstrong PW, Baigrie RS, Daly PA et al. Tissue plasminogen activator: Toronto (TPAT) placebo-controlled randomized trial in acute myocardial infarction. J Am Coll Cardiol 1989; 13: 1469-1476.
  • Lavie CJ, O'Keefe JH Jr, Chesebro JH, Clements IP, Gibbons RJ. Prevention of late ventricular dilatation after myocardial infarction by successful thrombolytic reperfusion. Am J Cardiol 1990; 66: 31-36.
  • Reimer KA, Lowe JE, Rasmussen MM, Jennings RB. The wave front phenomenon of ischemic cell death. 1. Myocardial infarct size vs. duration of coronary occlusion in dogs. Circulation 1977; 56: 786-794.
  • Reimer KA, Jennings RB. The wave front phenomenon of myocardial ischemic cell death. 11. Transmural progression of necrosis within the framework of ischemic bed size (myocardium at risk) and collateral flow. Lab Invest 1979; 40: 633-644.
  • Lavellee M, Cox D, Patrick TA, Vatner SF. Salvage of myocardial function by coronary artery reperfusion 1, 2, and 3 hours after occlusion in conscious dogs. Circ Res 1983; 53: 235-247.
  • Hong AS, Chae JS, Dubin SB, Lee S, Fishbein MC, Siegel RG. Ultrasonic clot disruption: an in vitro study. Am Heart J 1990; 120: 418-422.
  • Rosenschein U, Bernstein JJ, DiSegni E, Kaplinski E, Bernheim J, Rozenzsjn LN. Experimental ultrasonic angioplasty: disruption of atherosclerotic plaques and thrombi in vitro and arterial recanalization in vivo. J Am Coll Cardiol 1990; 15: 711-717.
  • Ariani M, Fishbein MC, Chae JS et al. Dissolution of peripheral arterial thrombi by ultrasound. Circulation 1991; 84: 1680-1688.
  • Hartnell CG, Saxton JM, Friedi SE, Abela GS. Rapid ablation of fresh thrombus by a new ultrasonic device--in vitro assessment. J Am Coll Cardiol 1992; 9: 108A (abstr).
  • Siegel RJ, Fishbein MC, Forrester J. Ultrasonic plaque ablation. A new method for recanalization of partially or totally occluded arteries. Circulation 1988; 78: 1443-1448.
  • Ernst A, Schenk EA, Gracewski SM et al. Ability of high-intensity ultrasound to ablate human atherosclerotic plaques and minimize debris size. Am J Cardiol 1991; 68: 242-246.
  • Ernst A, Schenk EA, Woodlock TJ et al. Feasibility of recanalization of human coronary arteries using high-intensity ultrasound. Am J Cardiol 1994; 73: 126-132.
  • Trubestein G, Engel C, Etzel F, Sobbe A, Cremer H, Stumpff U. Thrombolysis by ultrasound. Clin Sci Mol Med 1976; 51: 697s-698s.
  • Stumpff U. Ultrasonic thrombolysis. J Acoust Soc Am 1979; 65:541-544.
  • Siegel RJ, Cumberland DC, Myler RK, Don Michael AT. Percutaneous ultrasonic angioplasty: initial clinical experience. Lancet 1989; 2: 772-774.
  • Rosenschein U, Rozenszajn LA, Kraus L et al. Ultrasonic angioplasty in totally occluded peripheral arteries. Initial clinical, histological and angiographie results. Circulation 1991; 83: 1976-1986.
  • Rosenschein U, Roth A, Rassin T, Basan S, Laniado S, Miller HI. Analysis of coronary ultrasound thrombolysis endpoints in acute myocardial infarction (ACUTE trial). Results of the feasibility phase. Circulation 1997;95:1411-1416.
  • Kudo S. Thrombolysis with ultrasound effect. Tokyo Jikeikai Med J 1989; 104: 1005-1012.
  • Francis CW, Önundarson PT, Carstensen EL et al. Enhancement of fibrinolysis in vitro by ultrasound. J Clin Invest 1992; 90: 2063-2068.
  • Blinc A, Francis CW, Trudnowski JE, Carstensen EL. Characterization of ultrasound-potentiated fibrinolysis in vitro. Blood 1993; 81:2636-2643.
  • Harpaz D, Chen X, Francis CW, Marder VJ, Meltzer RS. Ultrasound enhancement of thrombolysis and reperfusion in vitro. J Am Coll Cardiol 1993; 21: 1507-1511.
  • Harpaz D, Chen X, Francis CW, Meltzer RS. Ultrasound accelerates urokinase-induced thrombolysis and reperfusion. Am Heart) 1994; 127: 1211-1219.
  • Nilsson AM, Odselius R, Roijer OA, Olsson SB. Pro- and antifibrinolytic effects of ultrasound on streptokinase-induced thrombolysis. Ultrasound Med Biol 1995; 21: 833-840.
  • Braaten JV, Goss RA, Francis CW. Ultrasound reversibly disaggregates fibrin fibers. Thromb Haemost 1997; 78: 1063-1068.
  • Siddiqi F, Odrljin TM, Fay PJ, Cox C, Francis CW. Binding of tissue-plasminogen activator to fibrin: effect of ultrasound. Blood 1998; 91: 2019-2025.
  • Siddiqi F, Blinc A, Braaten JV, Francis CW. Ultrasound increases flow through fibrin gels. Thromb Haemost 1995; 73: 495-498.
  • Francis CW, Blinc A, Lee S, Cox C. Ultrasound accelerates transport of recombinant tissue plasminogen activator into clots. Ultrasound Med Biol 1995; 21: 419-424.
  • Akiyama M, Ishibashi Y, Yamada T, Furuhata H. Low frequent ultrasound penetrates the cranium and enhances thrombolysis in vitro. Neurosurgery 1988; 43: 828-833.
  • Luo H, Birnbaum Y, Fishbein MC et al. Enhancement of thrombolysis in vivo without skin and soft tissue damage by transcutaneous ultrasound. Thromb Res 1998; 89: 171-177.
  • Riggs PN, Francis CW, Bartos SR, Penney DP. Ultrasound enhancement of rabbit femoral artery thrombolysis. Cardiovasc Surg 1997; 5: 201-207.
  • Larsson J, Carlson J, Olsson SB. Ultrasound-enhanced thrombolysis in experimental retinal vein occlusion in the rabbit. Br J Ophthalmol 1988; 82: 1438-1440.
  • Kashyap A, Blinc A, Marder VJ, Penney DP, Francis CW. Acceleration of fibrinolysis by ultrasound in a rabbit ear model of small vessel injury. Thromb Res 1994; 76: 475-485.
  • Kornowski R, Meltzer RS, Chemine A, Vered Z, Battler A. Does external ultrasound accelerate thrombolysis? Results from a rabbit model. Circulation 1994; 89: 339-344.
  • Tachibana K, Tachibana S. Albumin microbubble echo-contrast material as an enhancer for ultrasound accelerated thrombolysis. Circulation 1995; 92: 1148-1150.

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