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New Genetics and Society
Critical Studies of Contemporary Biosciences
Volume 28, 2009 - Issue 4
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Articles

Framing genetic risk: trust and credibility markers in online direct-to-consumer advertising for genetic testing

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Pages 339-362 | Published online: 17 Nov 2009

References

  • ACMG (American College of Medicine Genetics Board of Directors), 2004. ACMG statement on direct to consumer genetic testing, Genetics in Medicine 6 (1) (2004), p. 60, [online]. Available from: http://www.acmg.net/resources/policies/Direct_Consumer_Testing.pdf [Accessed 10 July 2007].
  • Alhakami, A., and Slovic, P., 1994. A psychological study of the inverse relationship between perceived risk and perceived benefit, Risk Analysis 14 (6) (1994), pp. 1085–1096.
  • ASCO, 1996. American Society of Clinical Oncology Policy Statement Update: Genetic Testing for Cancer Susceptibility, Journal of Clinical Oncology 21 (12) (1996), pp. 1–10.
  • ASHG (American Society of Human Genetics), 2007. ASHG statement on direct-to-consumer genetic testing in the United States, American Journal of Human Genetics 81 (2007), pp. 631–637.
  • Behrman, R. E., 2005. "The Impact of Direct-to-Consumer Drug Advertising on Seniors' Health and Health Care Costs. Senate Special Committee on Aging. First Session, 29 September". Vol. 30. Washington, DC: US Government Printing Office; 2005, [online]. Available from: http://www.fda.gov/ola/2005/idcda0929.html [Accessed 25 April 2008].
  • Berger, J. T., et al., 2001. Direct to consumer drug marketing: public service or disservice?, Mount Sinai Journal of Medicine 68 (3) (2001), pp. 197–202.
  • Breakwell, G., 2007. The psychology of risk. Cambridge University Press; 2007.
  • Briggs, P., Burford, B., and De Angeli, A., 2002. Trust in online advice, Social Science Computer Review 20 (3) (2002), pp. 321–332.
  • Burke, W., Pinsky, L., and Press, N. A., 2003. Categorizing genetic tests to identify their ethical, legal, and social implications, American Journal of Medical Genetics 106 (3) (2003), pp. 233–240.
  • California Department of Public Health, 2008. Genetic test cease and desist notices, (2008), [online]. Available from: http://www.cdph.ca.gov/HealthInfo/news/Pages/LabTestLandingPg.aspx [Accessed 12 October 2008].
  • Carroll, J. C., et al., 2008. Genetic services for hereditary breast/ovarian and colorectal cancers – physicians' awareness, use and satisfaction, Community Genetics 11 (1) (2008), pp. 43–51.
  • Castle, D., and Ries, N. M., 2007. Ethical, legal and social issues in nutrigenomics: the challenges of regulating service delivery and building health professional capacity, Mutation Research 622 (2007), pp. 138–143.
  • Collins, F. S., and Guttmacher, A. E., 2001. Genetics moves into the medical mainstream, Journal of the American Medical Association 286 (18) (2001), pp. 2322–2324.
  • Corritore, C., Kracher, B., and Wiedenbeck, S., 2003. On-line trust: concepts, evolving themes, a model, International Journal of Human-Computer Studies 58 (2003), pp. 737–758.
  • Croyle, R. T., and Lerman, C., 1999. Risk communication in genetic testing for cancer susceptibility, Journal of the National Cancer Institute Monographs 25 (1999), pp. 59–66.
  • Davis, J., 2007. The effect of qualifying language on perceptions of drug appeal, drug experience, and estimates of side-effect incidence in DTC advertising, Journal of Health Communication 12 (2007), pp. 607–622.
  • Donohue, J. M., Cevasco, M., and Rosenthal, M. B., 2007. A decade of direct-to-consumer advertising of prescription drugs, New England Journal of Medicine 357 (2007), pp. 673–681.
  • Faden, R. R., and Beauchamp, T. L., 1986. A history and theory of informed consent. Oxford: Oxford University Press; 1986.
  • Federal Trade Commission, 2006. A healthy dose of skepticism may be the best prescription [online], (2006), Available from: http://www.ftc.gov/bcp/edu/pubs/consumer/health/hea02.shtm [Accessed 25 April 2008].
  • Fogg, B. J., et al., 2001. What makes websites credible? A report on a large quantitative study. Presented at Proceedings of the SIGCHI conference on human factors in computing systems. Seattle, Washington, US, .
  • Frosch, D. L., et al., 2007. Creating demand for prescription drugs: a content analysis of television direct-to-consumer advertising, Annals of Family Medicine 5 (2007), pp. 6–13.
  • Gellad, Z. F., and Lyles, K. W., 2007. Direct-to-consumer advertising of pharmaceuticals, American Journal of Medicine 120 (2007), pp. 475–480.
  • Genetic Alliance, 2007. "Comments to the Food and Drug Administration (FDA) in response to their Draft Guidance on in vitro diagnostic multivariate index assays (IVDMIAs) [online]". 2007, Prepared by the Consumer Task Force on Genetic Testing Convener: Sharon F. Terry, President & CEO, Genetic Alliance, 22 February. Available from: http://www.geneticalliance.org/ws_display.asp?filter=policy.ivdmia.comments [Accessed 27 February 2008].
  • Genetic Alliance, 2008. Comments to the Secretary's Advisory Committee on Genetics, Health and Society on oversight of genetic tests (2008), Available from: http://geneticalliance.org/ [Accessed 5 February 2008].
  • Genetics and Public Policy Center, 2007. Survey of direct-to-consumer testing statutes and regulations [online], (2007), Available from: http://www.dnapolicy.org/resources/DTCStateLawChart.pdf [Accessed 25 April 2008].
  • Genetics Home Reference, 2008. What is direct to consumer genetic testing? [online], (2008), Available from: http://ghr.nlm.nih.gov/handbook/testing/directtoconsumer;jsessionid=1F2B3221702C464445AAB037576C274C [Accessed 25 April 2008].
  • GeneWatch, 2007. Letters from retailers rejecting Sciona's tests [online], (2007), Available from: http://www.genewatch.org/sub-529056 [Accessed 17 August 2007].
  • Geransar, R. M., and Einsiedel, E. F., 2008. Evaluating online direct-to-consumer marketing of genetic tests: informed choices or buyers beware?, Genetic Testing 12 (1) (2008), pp. 13–23.
  • Goddard, K. A., et al., 2007. Awareness and use of direct-to-consumer nutrigenomic tests, United States, 2006, Genetics in Medicine 9 (8) (2007), pp. 510–517.
  • Gollust, S. E., Wilfond, B. S., and Hull, S. C., 2003. Direct-to-consumer sales of genetic services on the Internet, Genetics and Medicine 5 (4) (2003), pp. 332–337.
  • Government Accountability Office, 2006. Nutrigenetic testing: tests purchased from four web sites mislead consumers [online], (2006), Available from: http://www.gao.gov/new.itlems/d06977t.pdf [Accessed 25 April 2008].
  • Grabner-Kräuter, S., and Kaluscha, E., 2003. Empirical research in on-line trust: a review and critical assessment, International Journal of Human-Computer Studies 58 (2003), pp. 783–812.
  • Gray, S., and Olopade, O., 2003. Direct-to-consumer marketing of genetic tests for cancer: buyer beware, Journal of Clinical Oncology 21 (17) (2003), pp. 3191–3193.
  • Grody, W. W., et al., 2001. American College of Medical Genetics consensus statement on Factor V Leiden mutation testing, Genetic Medicine 3 (2001), pp. 139–148.
  • Higashi, M. K., and Veenstra, D. L., 2003. Managed care in the genomics era: assessing the cost-effectiveness of genetic tests, American Journal of Managed Care 9 (2003), pp. 493–500.
  • Hogarth, S., Javitt, G., and Melzer, D., 2008. The current landscape for direct-to-consumer genetic testing: legal, ethical, and policy issues, Annual Review of Genomics and Human Genetics 9 (2008), pp. 161–182.
  • Holmer, A. F., 1999. Direct-to-consumer prescription drug advertising builds bridges between patients and physicians, Journal of the American Medical Association 281 (4) (1999), pp. 380–382.
  • Holmer, A. F., 2002. Direct-to-consumer advertising – strengthening our health care system, New England Journal of Medicine 346 (7) (2002), pp. 526–528.
  • Hudson, K., et al., 2007. American Society of Human Genetics Social Issue Committee. ASHG Statement on direct-to-consumer genetic testing in the United States, Obstetrics and Gynecology 110 (6) (2007), pp. 1392–1395.
  • Human Genetics Commission, 2003. Genes direct: ensuring the effective oversight of genetic tests supplied directly to the public [online], (2003), Available from: http://www.hgc.gov.uk/UploadDocs/DocPub/Document/genesdirect_full.pdf [Accessed 26 April 2008].
  • Human Genetics Commission, 2007. More genes direct: a report on developments in the availability, marketing and regulation of genetics tests supplied directly to the public [online], (2007), Available from: http://www.hgc.gov.uk/UploadDocs/DocPub/Document/More%20Genes%20Direct%20-%20final.pdf [Accessed 26 April 2008].
  • Janssens, A. C.J.W., et al., 2006. Predictive genetic testing for type 2 diabetes, British Medical Journal 333 (7657) (2006), pp. 509–510.
  • Lewicki, R. J., and Bunker, B. B., 1996. "Developing and maintaining trust in working relationships". In: Kramer, R. M., and Tyler, T. R., eds. Trust in organizations: frontiers of theory and research. Thousand Oaks, CA: Sage; 1996. pp. 114–139.
  • Lewis, J. D., and Weigart, A., 1985. Trust as a social reality, Social Forces 63 (4) (1985), pp. 967–985.
  • Lexchin, J., and Mintzes, B., 2002. Direct-to-consumer advertising of prescription drugs: the evidence says no, Journal of Public Policy and Marketing 21 (2002), pp. 194–201.
  • Loewenstein, G. F., et al., 2001. Risk as feelings, Psychological Bulletin 127 (2) (2001), pp. 267–286.
  • Luhman, N., 1988. "Familiarity, confidence, trust: problems and alternatives". In: Gambetta, D., ed. Trust: making and breaking cooperative relations. New York: Basil Blackwell; 1988. pp. 94–107.
  • Lyles, A., 2002. Direct marketing of pharmaceuticals to consumers, Annual Review of Public Health 23 (2002), pp. 73–91.
  • Mayer, R. C., Davis, J. H., and Schoorman, F. D., 1995. An integrative model of organizational trust, Academy of Management Review 20 (3) (1995), pp. 709–734.
  • Metzl, J. M., and Howell, J. D., 2004. Making history: lessons from the Great Moments series of pharmaceutical advertisements, Academic Medicine 79 (11) (2004), pp. 1027–1032.
  • Morgan, S., 2007. Direct-to-consumer advertising and expenditures on prescription drugs: a comparison of experiences in the United States and Canada, Open Medicine 1 (1) (2007), pp. 675–681.
  • Murray, E., et al., 2004. Direct-to-consumer advertising: public perceptions of its effects on health behaviors, health care, and doctor-patient relationships, Journal of the American Board of Family Practice 17 (2004), pp. 6–18.
  • Myers, M. F., et al., 2006. Genetic testing for susceptibility to breast and ovarian cancer: evaluating the impact of a direct-to-consumer marketing campaign on physicians' knowledge and practices, Genetics in Medicine 8 (6) (2006), pp. 361–370.
  • National Human Genome Research Institute, 2004. Workshop summary: direct to consumer (DTC) advertising of genetic tests, (2004), 2004 [online]. Available from: http://www.genome.gov/12010660 [Accessed 9 October 2008].
  • Palumbo, F. B., and Mullins, C. D., 2002. The development of direct-to-consumer prescription drug advertising regulation, Food and Drug Law Journal 57 (3) (2002), pp. 423–443.
  • Pollack, A., 2008. Genetic testing questioned by regulators, New York Times (2008), [online]. Available from: http://www.nytimes.com/2008/06/26/business/26gene.html?8br [Accessed 12 October 2008].
  • Resnik, D. B., and Vorhaus, D. B., 2006. Genetic modification and genetic determinism, Philosophy, Ethics, and Humanities in Medicine 1 (9) (2006), [online]. Available from: http://www.peh-med.com/content/1/1/9 [Accessed 6 June 2007].
  • Rosenthal, M. B., et al., 2002. Promotion of prescription drugs to consumers, New England Journal of Medicine 346 (7) (2002), pp. 498–505.
  • Rotter, J. B., 1971. Generalized expectancies for interpersonal trust, American Psychologist 26 (5) (1971), pp. 443–452.
  • SACGHS (Secretary's Advisory Committee on Genetics, Health and Society), 2004. A roadmap for the integration of genetics and health into health and society: the study priorities of the Secretary's Advisory Committee on Genetics, Health and Society, (2004), Available from: http://oba.od.nih.gov/oba/sacghs/reports/SACGHSPriorities.pdf [Accessed 9 October 2009].
  • SACGT (Secretary's Advisory Committee on Genetic Testing), 2000. Enhancing the oversight of genetic tests: recommendations of SACGT [online], (2000), Available from: http://www4.od.nih.gov/oba/sacgt/reports/oversight_report.pdf [Accessed 26 April 2008].
  • Senate Special Committee on Aging, 2005. "The Impact of Direct-to-Consumer Drug Advertising on Seniors' Health and Health Care Costs. First Session ed". Washington, DC: US Government Printing Office; 2005, 30 [online]. Available from: http://www.consumersunion.org/pub/core_health_care/002745.html [Accessed 26 April 2008].
  • Shields, A. E., Burke, W., and Levy, D. E., 2008. Differential use of available genetic tests among primary care physicians in the United States: results of a national survey, Genetics in Medicine 10 (6) (2008), pp. 404–414.
  • Sullivan, J. L., and Transue, J. E., 1999. The psychological underpinnings of democracy: a selective review of research on political tolerance, interpersonal trust, and social capital, Annual Review of Psychology 50 (1999), p. 625.
  • Takada Genetics Research Lab, 2008. Beyond the medicine: providing quality genetic testing services for the publics in the world [online]. Presented at International Symposium hosted by the Graduate School of Medical Sciences. 16 March, Available from: http://www.idenshi.jp/international/ [Accessed 9 October 2008].
  • Tambor, E. S., Rimer, B. K., and Strigo, T. S., 1998. Genetic testing for breast cancer susceptibility: awareness and interest among women in the general population, American Journal of Medical Genetics 68 (1) (1998), pp. 43–49.
  • Taylor-Gooby, P., and Zinn, J. O., 2004. Current directions in risk research: new developments in psychology and sociology, Risk Analysis 26 (2) (2004), pp. 397–412.
  • Tomes, N., 2005. The great American medicine show revisited, Bulletin of the History of Medicine 79 (2005), pp. 627–663.
  • Tracy, E. E., 2007. Are doctors prepared for direct-to-consumer advertising of genetic tests?, Obstetrics and Gynecology 110 (6) (2007), pp. 1389–1391.
  • Walls, J., et al., 2004. Critical trust: understanding lay perceptions of health and safety risk regulation, Health, Risk and Society 6 (2004), pp. 133–150.
  • Warren, M., 1999. Democracy and trust. Cambridge University Press; 1999.
  • Wasson, K., Cook, E., and Helzlsouer, K., 2006. Direct to consumer online genetic testing and the four principles: an analysis of ethical issues, Ethics and Medicine 22 (2) (2006), pp. 403–414.
  • Wilkes, M. S., Bell, R. A., and Kravitz, R. L., 2000. Direct-to-consumer prescription drug advertising: trends, impact, and implications, Health Affairs 19 (2) (2000), pp. 110–128.
  • Williams-Jones, B., 2006. “Be ready against cancer, now”: direct-to-consumer advertising for genetic testing, New Genetics and Society 25 (1) (2006), pp. 89–107.
  • Yang, N., et al., 2003. ACTN3 Genotype is associated with human elite athletic performance, American Journal of Human Genetics 73 (2003), pp. 627–631.
  • Young, J. H., 1966, 1992. The medical messiahs: a social history of health quackery in twentieth-century America [online], (1966, 1992), Available from: http://www.quackwatch.org/13Hx/MM/02.html [Accessed 9 October 2008].

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