Voluntary suspension of medically-assisted reproduction during the COVID-19 pandemic in Japan: a nationwide internet survey

References

• Adhikari, B., & Cheah, P. Y. (2021). Vaccine hesitancy in the COVID-19 era. The Lancet Infectious Diseases, 21(8), 1086. https://doi.org/10.1016/S1473–3099(21)00390-X
   PubMed Web of Science ®Google Scholar
• Ahorsu, D. K., Lin, C. Y., Imani, V., Saffari, M., Griffiths, M. D., & Pakpour, A. H. (2022). The fear of COVID-19 scale: development and initial validation. International Journal of Mental Health and Addiction, 20(3), 1537–1545. https://doi.org/10.1007/s11469–020–00270–8
   PubMed Web of Science ®Google Scholar
• ASRM. (2021). American society for reproductive medicine. https://www.asrm.org/globalassets/asrm/asrm-content/news-and-publications/covid-19/covidtaskforce.pdf
   Google Scholar
• Austin, P. C., & Brunner, L. J. (2004). Inflation of the type I error rate when a continuous confounding variable is categorized in logistic regression analyses. Statistics in Medicine, 23(7), 1159–1178. https://doi.org/10.1002/sim.1687
   PubMed Web of Science ®Google Scholar
• Barra, F., La Rosa, V. L., Vitale, S. G., Commodari, E., Altieri, M., Scala, C., & Ferrero, S. (2022). Psychological status of infertile patients who had in vitro fertilization treatment interrupted or postponed due to COVID-19 pandemic: a cross-sectional study. Journal of Psychosomatic Obstetrics and Gynaecology, 43(2), 145–152. https://doi.org/10.1080/0167482X.2020.1853095
   PubMed Web of Science ®Google Scholar
• Bedrick, B. S., Anderson, K., Broughton, D. E., Hamilton, B., & Jungheim, E. S. (2019). Factors associated with early in vitro fertilization treatment discontinuation. Fertility and Sterility, 112(1), 105–111. https://doi.org/10.1016/j.fertnstert.2019.03.007
   PubMed Web of Science ®Google Scholar
• Ben-Kimhy, R., Youngster, M., Medina-Artom, T. R., Avraham, S., Gat, I., Marom Haham, L., Hourvitz, A., & Kedem, A. (2020). Fertility patients under COVID-19: attitudes, perceptions and psychological reactions. Human Reproduction (Oxford, England), 35(12), 2774–2783. https://doi.org/10.1093/humrep/deaa248
   PubMed Web of Science ®Google Scholar
• Biviá-Roig, G., Boldó-Roda, A., Blasco-Sanz, R., Serrano-Raya, L., DelaFuente-Díez, E., Múzquiz-Barberá, P., & Lisón, J. F. (2021). Impact of the COVID-19 pandemic on the lifestyles and quality of life of women with fertility problems: a cross-sectional study. Frontiers in Public Health, 9, 686115. https://doi.org/10.3389/fpubh.2021.686115
   PubMed Web of Science ®Google Scholar
• Boivin, J., Griffiths, E., & Venetis, C. A. (2011). Emotional distress in infertile women and failure of assisted reproductive technologies: meta-analysis of prospective psychosocial studies. BMJ (Clinical Research ed.), 342, d223. https://doi.org/10.1136/bmj.d223
   PubMed Web of Science ®Google Scholar
• Boivin, J., Harrison, C., Mathur, R., Burns, G., Pericleous-Smith, A., & Gameiro, S. (2020). Patient experiences of fertility clinic closure during the COVID-19 pandemic: appraisals, coping and emotions. Human Reproduction, 35(11), 2556–2566. https://doi.org/10.1093/humrep/deaa218
   PubMed Web of Science ®Google Scholar
• Brochu, F., Robins, S., Miner, S. A., Grunberg, P. H., Chan, P., Lo, K., Holzer, H. E. G., Mahutte, N., Ouhilal, S., Tulandi, T., & Zelkowitz, P. (2019). Searching the internet for infertility information: a survey of patient needs and preferences. Journal of Medical Internet Research, 21(12), e15132. https://doi.org/10.2196/15132
   PubMed Web of Science ®Google Scholar
• Chua, S. J., Danhof, N. A., Mochtar, M. H., van Wely, M., McLernon, D. J., Custers, I., Lee, E., Dreyer, K., Cahill, D. J., Gillett, W. R., Righarts, A., Strandell, A., Rantsi, T., Schmidt, L., Eijkemans, M. J. C., Mol, B. W. J., & van Eekelen, R. (2020). Age-related natural fertility outcomes in women over 35 years: a systematic review and individual participant data meta-analysis. Human Reproduction (Oxford, England), 35(8), 1808–1820. https://doi.org/10.1093/humrep/deaa129
   PubMed Web of Science ®Google Scholar
• Courvoisier, D. S., Combescure, C., Agoritsas, T., Gayet-Ageron, A., & Perneger, T. V. (2011). Performance of logistic regression modeling: beyond the number of events per variable, the role of data structure. Journal of Clinical Epidemiology, 64(9), 993–1000. https://doi.org/10.1016/j.jclinepi.2010.11.012
   PubMed Web of Science ®Google Scholar
• Eisenberg, M. L., Smith, J. F., Millstein, S. G., Nachtigall, R. D., Adler, N. E., Pasch, L. A., & Katz, P. P, Infertility Outcomes Program Project Group. (2010). Predictors of not pursuing infertility treatment after an infertility diagnosis: examination of a prospective U.S. cohort. Fertility and Sterility, 94(6), 2369–2371. https://doi.org/10.1016/j.fertnstert.2010.03.068
   PubMed Web of Science ®Google Scholar
• European Society for Human Reproduction and Embryology (ESHRE). (2021). Coronavirus Covid-19: ESHRE statement on pregnancy and conception. https://www.eshre.eu/Press-Room/ESHRE-News
   Google Scholar
• Every-Palmer, S., Jenkins, M., Gendall, P., Hoek, J., Beaglehole, B., Bell, C., Williman, J., Rapsey, C., & Stanley, J. (2020). Psychological distress, anxiety, family violence, suicidality, and wellbeing in New Zealand during the COVID-19 lockdown: A cross-sectional study. PloS One, 15(11), e0241658. https://doi.org/10.1371/journal.pone.0241658
   PubMed Web of Science ®Google Scholar
• Furukawa, T. A., Kawakami, N., Saitoh, M., Ono, Y., Nakane, Y., Nakamura, Y., Tachimori, H., Iwata, N., Uda, H., Nakane, H., Watanabe, M., Naganuma, Y., Hata, Y., Kobayashi, M., Miyake, Y., Takeshima, T., & Kikkawa, T. (2008). The performance of the Japanese version of the K6 and K10 in the World Mental Health Survey Japan. International Journal of Methods in Psychiatric Research, 17(3), 152–158. https://doi.org/10.1002/mpr.257
   PubMed Web of Science ®Google Scholar
• Gameiro, S., Boivin, J., Peronace, L., & Verhaak, C. M. (2012). Why do patients discontinue fertility treatment? A systematic review of reasons and predictors of discontinuation in fertility treatment. Human Reproduction Update, 18(6), 652–669. https://doi.org/10.1093/humupd/dms031
   PubMed Web of Science ®Google Scholar
• Greil, A. L., Shreffler, K. M., Schmidt, L., & McQuillan, J. (2011). Variation in distress among women with infertility: evidence from a population-based sample. Human Reproduction (Oxford, England), 26(8), 2101–2112. https://doi.org/10.1093/humrep/der148
   PubMed Web of Science ®Google Scholar
• Groenwold, R. H., Klungel, O. H., Altman, D. G., van der Graaf, Y., Hoes, A. W., & Moons, K. G, PROTECT WP2 (Pharmacoepidemiological Research on Outcomes of Therapeutics by a European Consortium, Work Programme 2 [Framework for pharmacoepidemiology studies]). (2013). Adjustment for continuous confounders: an example of how to prevent residual confounding. CMAJ : Canadian Medical Association Journal = Journal de L'Association Medicale Canadienne, 185(5), 401–406. https://doi.org/10.1503/cmaj.120592
   PubMed Web of Science ®Google Scholar
• Haagen, E. C., Tuil, W., Hendriks, J., de Bruijn, R. P., Braat, D. D., & Kremer, J. A. (2003). Current Internet use and preferences of IVF and ICSI patients. Human Reproduction (Oxford, England), 18(10), 2073–2078. https://doi.org/10.1093/humrep/deg423
   PubMed Web of Science ®Google Scholar
• Huang, C., Wang, Y., Li, X., Ren, L., Zhao, J., Hu, Y., Zhang, L., Fan, G., Xu, J., Gu, X., Cheng, Z., Yu, T., Xia, J., Wei, Y., Wu, W., Xie, X., Yin, W., Li, H., Liu, M., … Cao, B. (2020). Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet (London, England), 395(10223), 497–506. https://doi.org/10.1016/S0140–6736(20)30183–5
   PubMed Web of Science ®Google Scholar
• Ishihara, O., Jwa, S. C., Kuwahara, A., Katagiri, Y., Kuwabara, Y., Hamatani, T., Harada, M., & Osuga, Y. (2021). Assisted reproductive technology in Japan: A summary report for 2018 by the Ethics Committee of the Japan Society of Obstetrics and Gynecology. Reproductive Medicine and Biology, 20(1), 3–12. https://doi.org/10.1002/rmb2.12358
   PubMed Web of Science ®Google Scholar
• Johansson, M., Adolfsson, A., Berg, M., Francis, J., Hogström, L., Janson, P. O., Sogn, J., & Hellström, A. L. (2010). Gender perspective on quality of life, comparisons between groups 4–5.5 years after unsuccessful or successful IVF treatment. Acta Obstetricia et Gynecologica Scandinavica, 89(5), 683–691 https://doi.org/10.3109/00016341003657892
   PubMed Web of Science ®Google Scholar
• JSOB. (2021). Japan Society of Obstetric and Gynecology certified facility. https://www.jsog.or.jp/facility_program/search_facility.php
   Google Scholar
• JSRM. (2020). Japan Sciety for Reproductive Medicine. http://www.jsrm.or.jp/announce/index.html
   Google Scholar
• Kamath, M. S., Joseph, T., Karuppusami, R., Chinta, P., Pal, A., Nallamilli, S. R., Sarkar, S., Poobalan, A., & Kunjummen, A. T. (2021). Knowledge, anxiety levels and attitudes of infertile couples towards COVID-19 and its impact on self-funded fertility treatment: a cross-sectional questionnaire survey. Human Reproduction Open, 2021(4), hoab039. https://doi.org/10.1093/hropen/hoab039
   PubMedGoogle Scholar
• Kessler, R. C., Andrews, G., Colpe, L. J., Hiripi, E., Mroczek, D. K., Normand, S. L., Walters, E. E., & Zaslavsky, A. M. (2002). Short screening scales to monitor population prevalences and trends in non-specific psychological distress. Psychological Medicine, 32(6), 959–976. https://doi.org/10.1017/s0033291702006074
   PubMed Web of Science ®Google Scholar
• Lopez Bernal, J., Andrews, N., Gower, C., Gallagher, E., Simmons, R., Thelwall, S., Stowe, J., Tessier, E., Groves, N., Dabrera, G., Myers, R., Campbell, C. N. J., Amirthalingam, G., Edmunds, M., Zambon, M., Brown, K. E., Hopkins, S., Chand, M., & Ramsay, M. (2021). Effectiveness of covid-19 vaccines against the B.1.617.2 (Delta) variant. The New England Journal of Medicine, 385(7), 585–594. https://doi.org/10.1056/NEJMoa2108891
   PubMed Web of Science ®Google Scholar
• Ma, Y., Xie, N., Xie, D., Sun, L., Li, S., Li, P., Li, Y., Li, J., Dong, Z., & Xie, X. (2019). A novel homozygous FBXO43 mutation associated with male infertility and teratozoospermia in a consanguineous Chinese family. Fertility and Sterility, 111(5), 909–917.e1. https://doi.org/10.1016/j.fertnstert.2019.01.007
   PubMed Web of Science ®Google Scholar
• Mamun, M. A., Sakib, N., Gozal, D., Bhuiyan, A. I., Hossain, S., Bodrud-Doza, M., Al Mamun, F., Hosen, I., Safiq, M. B., Abdullah, A. H., Sarker, M. A., Rayhan, I., Sikder, M. T., Muhit, M., Lin, C. Y., Griffiths, M. D., & Pakpour, A. H. (2021). The COVID-19 pandemic and serious psychological consequences in Bangladesh: A population-based nationwide study. Journal of Affective Disorders, 279, 462–472. https://doi.org/10.1016/j.jad.2020.10.036
   PubMed Web of Science ®Google Scholar
• Mantel, N. (1970). Why stepdown procedures in variable selection. Technometrics, 12(3), 621–625. https://doi.org/10.1080/00401706.1970.10488701
   Web of Science ®Google Scholar
• Marom Haham, L., Youngster, M., Kuperman Shani, A., Yee, S., Ben-Kimhy, R., Medina-Artom, T. R., Hourvitz, A., Kedem, A., & Librach, C. (2021). Suspension of fertility treatment during the COVID-19 pandemic: views, emotional reactions and psychological distress among women undergoing fertility treatment. Reproductive Biomedicine Online, 42(4), 849–858. https://doi.org/10.1016/j.rbmo.2021.01.007
   PubMed Web of Science ®Google Scholar
• Mascarenhas, M. N., Flaxman, S. R., Boerma, T., Vanderpoel, S., & Stevens, G. A. (2012). National, regional, and global trends in infertility prevalence since 1990: a systematic analysis of 277 health surveys. PLoS Medicine, 9(12), e1001356. https://doi.org/10.1371/journal.pmed.1001356
   PubMed Web of Science ®Google Scholar
• Masuyama, A., Shinkawa, H., & Kubo, T. (2022). Validation and psychometric properties of the japanese version of the fear of COVID-19 scale among adolescents. International Journal of Mental Health and Addiction, 20(1), 387–397. https://doi.org/10.1007/s11469–020–00368-z
   PubMed Web of Science ®Google Scholar
• Matthiesen, S. M., Frederiksen, Y., Ingerslev, H. J., & Zachariae, R. (2011). Stress, distress and outcome of assisted reproductive technology (ART): a meta-analysis. Human Reproduction (Oxford, England), 26(10), 2763–2776. https://doi.org/10.1093/humrep/der246
   PubMed Web of Science ®Google Scholar
• Ministry of Health Labour and Welfare (MHLW). (2021). MHLW Press Conference. https://www.mhlw.go.jp/stf/seisakunitsuite/bunya/newpage_00032.html
   Google Scholar
• Muhaidat, N., Alshrouf, M. A., Karam, A. M., & Elfalah, M. (2021). infertility management disruption during the COVID-19 outbreak in a middle-income country: patients’ choices, attitudes, and concerns. Patient Preference and Adherence, 15, 2279–2288. https://doi.org/10.2147/PPA.S327055
   PubMed Web of Science ®Google Scholar
• National Institute of Population and Social Security Research. (2015). Marriage and childbirth in Japan today (in Japanese). http://www.ipss.go.jp/ps-doukou/j/doukou15/NFS15_reportALL.pdf
   Google Scholar
• Ota, K., Tsutsumi, O., Mitani, T., Morimoto, Y., Tanaka, A., Osuga, Y., Takahashi, T., & Hosoi, Y. (2021). Reproductive medical providers’ behaviors, considerations, and plans for fertility treatments during the COVID-19 pandemic in Japan: A nationwide web-based survey. Reproductive Medicine and Biology, 20(2), 123–132. https://doi.org/10.1002/rmb2.12372
   PubMed Web of Science ®Google Scholar
• Pasch, L. A., Holley, S. R., Bleil, M. E., Shehab, D., Katz, P. P., & Adler, N. E. (2016). Addressing the needs of fertility treatment patients and their partners: are they informed of and do they receive mental health services? Fertility and Sterility, 106(1), 209–215.e2. https://doi.org/10.1016/j.fertnstert.2016.03.006
   PubMed Web of Science ®Google Scholar
• Pearson, K. R., Hauser, R., Cramer, D. W., & Missmer, S. A. (2009). Point of failure as a predictor of in vitro fertilization treatment discontinuation. Fertility and Sterility, 91(4 Suppl), 1483–1485. https://doi.org/10.1016/j.fertnstert.2008.07.1732
   PubMed Web of Science ®Google Scholar
• Pedro, J., Sobral, M. P., Mesquita-Guimarães, J., Leal, C., Costa, M. E., & Martins, M. V. (2017). Couples’ discontinuation of fertility treatments: a longitudinal study on demographic, biomedical, and psychosocial risk factors. Journal of Assisted Reproduction and Genetics, 34(2), 217–224. https://doi.org/10.1007/s10815–016–0844–8
   PubMed Web of Science ®Google Scholar
• Peduzzi, P., Concato, J., Kemper, E., Holford, T. R., & Feinstein, A. R. (1996). A simulation study of the number of events per variable in logistic regression analysis. Journal of Clinical Epidemiology, 49(12), 1373–1379.
   PubMed Web of Science ®Google Scholar
• Pericleous-Smith, A., Dark, S., McCluskey, G., Mizen, L., & Crawshaw, M. (2021). Survey of fertility counselling provision in UK licensed treatment centres during the first phase of the COVID-19 pandemic. Human Fertility, 1–11. https://doi.org/10.1080/14647273.2021.1898053
   Web of Science ®Google Scholar
• Prime Minister’s Office of Japan. (2020). Declaration of a State of Emergency in response to the Novel Coronavirus Disease. https://japan.kantei.go.jp/ongoingtopics/_00020.html
   Google Scholar
• Romanski, P. A., Bortoletto, P., Rosenwaks, Z., & Schattman, G. L. (2020). Delay in IVF treatment up to 180 days does not affect pregnancy outcomes in women with diminished ovarian reserve. Human Reproduction (Oxford, England), 35(7), 1630–1636. https://doi.org/10.1093/humrep/deaa137
   PubMed Web of Science ®Google Scholar
• Sbaragli, C., Morgante, G., Goracci, A., Hofkens, T., De Leo, V., & Castrogiovanni, P. (2008). Infertility and psychiatric morbidity. Fertility and Sterility, 90(6), 2107–2111. https://doi.org/10.1016/j.fertnstert.2007.10.045
   PubMed Web of Science ®Google Scholar
• Statistical Bureau of Japan. (2021). Population estimates as of October 1, 2021. https://www.stat.go.jp/english/index.html
   Google Scholar
• Tabuchi, T., Shinozaki, T., Kunugita, N., Nakamura, M., & Tsuji, I. (2019). Study profile: The Japan "Society and New Tobacco" Internet Survey (JASTIS): A longitudinal internet cohort study of heat-not-burn tobacco products, electronic cigarettes, and conventional tobacco products in Japan. Journal of Epidemiology, 29(11), 444–450. https://doi.org/10.2188/jea.JE20180116
   PubMed Web of Science ®Google Scholar
• Ueda, M., Stickley, A., Sueki, H., & Matsubayashi, T. (2020). Mental health status of the general population in Japan during the COVID-19 pandemic. Psychiatry and Clinical Neurosciences, 74(9), 505–506. https://doi.org/10.1111/pcn.13105
   PubMed Web of Science ®Google Scholar
• VanderWeele, T. J. (2019). Principles of confounder selection. European Journal of Epidemiology, 34(3), 211–219. https://doi.org/10.1007/s10654–019–00494–6
   PubMed Web of Science ®Google Scholar
• Vaughan, D. A., Shah, J. S., Penzias, A. S., Domar, A. D., & Toth, T. L. (2020). Infertility remains a top stressor despite the COVID-19 pandemic. Reproductive Biomedicine Online, 41(3), 425–427. https://doi.org/10.1016/j.rbmo.2020.05.015
   PubMed Web of Science ®Google Scholar
• Wang, Y., Kala, M. P., & Jafar, T. H. (2020). Factors associated with psychological distress during the coronavirus disease 2019 (COVID-19) pandemic on the predominantly general population: A systematic review and meta-analysis. PloS One, 15(12), e0244630. https://doi.org/10.1371/journal.pone.0244630
   PubMed Web of Science ®Google Scholar
• Wilson, N., Mansoor, O. D., Boyd, M. J., Kvalsvig, A., & Baker, M. G. (2021). We should not dismiss the possibility of eradicating COVID-19: comparisons with smallpox and polio. BMJ Global Health, 6(8), e006810. https://doi.org/10.1136/bmjgh-2021–006810
   PubMed Web of Science ®Google Scholar
• Wischmann, T., Korge, K., Scherg, H., Strowitzki, T., & Verres, R. (2012). A 10-year follow-up study of psychosocial factors affecting couples after infertility treatment. Human Reproduction (Oxford, England), 27(11), 3226–3232. https://doi.org/10.1093/humrep/des293
   PubMed Web of Science ®Google Scholar
• WORLDMETER. (2021). https://www.worldometers.info/coronavirus/
   Google Scholar
• Xiong, J., Lipsitz, O., Nasri, F., Lui, L. M. W., Gill, H., Phan, L., Chen-Li, D., Iacobucci, M., Ho, R., Majeed, A., & McIntyre, R. S. (2020). Impact of COVID-19 pandemic on mental health in the general population: A systematic review. Journal of Affective Disorders, 277, 55–64. https://doi.org/10.1016/j.jad.2020.08.001
   PubMed Web of Science ®Google Scholar