Low oxygen tension and autologous plasma enhance T-cell proliferation and CD49d expression density in serum-free media

References

• Rooney CM, Smith CA, Ng CYC et al. Infusion of cytotoxic T cells for the prevention and treatment of Epstein—Barr virus-induced lymphoma in allogeneic transplant recipi-ents. Blood 1998;92:1549–55.
   PubMed Web of Science ®Google Scholar
• Riddell SR, Watanabe KS, Goodrich JM et al. Restoration ofviral immunity in immunodeficient humans by the adoptive transfer of T cell clones. Science 1992;257:238–41.
   PubMed Web of Science ®Google Scholar
• Heslop HE, Ng CY, Li C et al. Long-term restoration of immunity against Epstein—Barr virus infection by adoptive transfer of gene-modified virus-specific T lymphocytes. Nature Med 1996;2:551–5.
   PubMed Web of Science ®Google Scholar
• Walter EA, Greenberg PD, Gilbert MJ et al. Reconstitution of cellular immunity against cytomegalovirus in recipients of allogeneic bone marrow by transfer of T-cell clones from the donor. N Engl .7 Med 1995;333:103811.
   Google Scholar
• Mehta-Damani A, Markowicz S, Engleman EG. Generation of antigen-specific CD8+ CTLs from naive precursors. Immunol 1994;153: 996–1003.
   Google Scholar
• Peshwa MV, Page LA, Qtan L et al. Generation and ex vivo expansion of HTLV-1 CD8+ cytotoxic T-lymphocytes for adoptive immunotherapy. Biotechnol Bioeng 1996;50:529–40.
   Google Scholar
• Cheever MA, Chen W. Therapy with cultured T cells: prin-ciples revisited. Immunol Rev 1997;157:177–94.
   PubMed Web of Science ®Google Scholar
• Crossland KD, Lee VK, Chen W et al. T cells from tumor-immune mice nonspecifically expanded in vitro with anti-CD 3 plus IL-2 retain specific function in vitro and can eradicate disseminated leukemia in vivo. .7 Immunol1991;146:4414–20.
   PubMed Web of Science ®Google Scholar
• Guyton AC, Hall JE. Textbook of medical physiology. Philadelphia: W.B Saunders Company, 1996:513–23.
   Google Scholar
• Hevehan DL, Papoutsakis ET, Miller WM. Physiologically significant effects of pH and oxygen tension on granu-lopoiesis. Exp Hematol 2000;28:267–75.
   Google Scholar
• LaIuppa JA, Papoutsakis ET, Miller WM. Oxygen tension alters the effects of cytokines on the megakaryocyte, ery-throcyte, and granulocyte lineages. Exp Hematol 1998;26:835–43.
   Google Scholar
• Mostafa SS, Miller WM, Papoutsakis ET Oxygen tension influences the differentiation, maturation and apoptosis of human megakaryocytes. Br .7 Haematol 2000; 111:879–889.
   PubMed Web of Science ®Google Scholar
• Andersen V, Hellung-Larsen P and Sorensen SF. Optimal oxygen tension for human lymphocytes in culture. 7 Cell Physiol 1968;72: 149–52.
   Google Scholar
• Loeffler DA, Juneau PL, Masserant S. Influence of tumour physico—chemical conditions on interleukin-2-stimulated lymphocyte proliferation. Br .7 Cancer 1992;66: 619–22.
   Google Scholar
• Carswell KS, Weiss JW, Papoutsakis ET. Low oxygen ten-sion enhances the stimulation and proliferation of human T lymphocytes in the presence of interleukin-2. Cytotherapy 1999;2: 25–37.
   Google Scholar
• Trimble L, Perales MA, Knazek R, Lieberman J. Serum enhances the ex vivo generation of HIV-specific cytotoxic T cells. Biotechnol Bioeng 1996;50:521–8.
   Google Scholar
• Lamers CHJ, van de Griend RJ, Braakman E et al. Optimization of culture conditions for activation and large-scale expansion of human T lymphocytes for bispecific antibody-directed cellular immunotherapy. Int 7 Cancer 1992;51:973–9.
   PubMed Web of Science ®Google Scholar
• Finkelstein DM, Miller RG. Effects of culture media on lymphokine-activated killer effector phenotype and lytic capacity. Cancer Immunol Immunother 1991;33:103–8.
   Google Scholar
• Trimble LA, Xu Z, Lieberman J. Clonal expansion of anti-gen-specific CD8+ cytotoxic T lymphocytes is regulated by late exposure to serum to prevent apoptosis. 7 Immunol Methods 1999;225: 39–52.
   Google Scholar
• Gavrieli Y, Sherman Y, Ben-Sasson SA. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. 7 Cell Biol 1992;119: 493–501.
   Google Scholar
• Tosato G. Generation of Epstein—Barr virus (EBV)-immor-talized B cell lines. In: Coligan JE, Kruisbeck AM, Marguiles DH et al., editors. Current protocols in immunology. New York: John Wiley and Sons, 1991.
   Google Scholar
• Bejarano MT, Masucci MG, Klein G, Klein E. T-cell-mediated inhibition of EBV-induced B-cell transformation: recognition of virus particles. Int y Cancer 1988;42:359–64.
   Google Scholar
• Walpole RE and Myers RH. Probabilio and statistics for engi-neers and scientists. New York: Macmillan Publishing Company, 1993.
   Google Scholar
• Perola 0, Ripatti A, Pelkonen J. T-lymphocyte subpopula-tions do not express identical combinations of interleukin-2 receptor chains in the early phase of their activation and proliferation. Scand y Immunol 2000;52: 123–30.
   Google Scholar
• Hemler ME. VLA proteins in the integrin family: structures, functions, and their role on leukocytes. Annu Rev Immunol 1990;8:365–400.
   PubMed Web of Science ®Google Scholar
• Holzmann B, Weissman IL. Peyer's patch-specific lympho-cyte homing receptors consist of a VLA-4-like alpha chain associated with either of two integrin beta chains, one of which is novel. EMBO y1989;8:1735–41.
   PubMed Web of Science ®Google Scholar
• Berlin C, Bargatze RF, Campbell JJ, et al. a4 integrins medi-ate lymphocyte attachment and rolling under physiologic flow. Cell 1995;80:413–22.
   PubMed Web of Science ®Google Scholar
• Pacheco KA, Tarkowski M, Klemm J, Rosenwasser U. CD49d expression and function on allergen-stimulated T cells from blood and airway. Am 7 Respir Cell Mol Biol 1998;18:286–93.
   PubMed Web of Science ®Google Scholar
• Kelly KA, Rank RG. Identification of homing receptors that mediate the recruitment of CD4 T cells to the genital tract following intravaginal infection with Chlamydia trachomatis. Infect Immun 1997;65:5198–208.
   PubMed Web of Science ®Google Scholar
• Hamann A, Andrew DP, Jablonski-Westrich D et al. Role of a4-integrins in lymphocyte homing to mucosal tissues in vivo. y Immunol 1994;152:3282–93.
   Google Scholar
• Kuby J. Immunology. New York: W.H. Freeman and Company. 1997.
   Google Scholar
• Musci MA, Latinis KM, Koretzky GA. Signaling events in T lymphocytes leading to cellular activation or programmed cell death. Clin Immunol Immunopathol 1997;83:205–22.
   Google Scholar
• DeGrendele HC, Estess P, Siegelman MH. Requirement for CD44 in activated T cell extravasation into an inflamma-tory site. Science 1997;278: 672–5.
   Google Scholar
• Boise LH, Minn AJ, Thompson CB. Receptors that regulate T-cell susceptibility to apoptotic cell death. Ann N Y Acad Sci 1995;766:70–80.
   Google Scholar
• Vermes I, Haanen C, Steffens-Nakken H, Reutelingsperger C. A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V. 7 Immunol Methods 1995;184: 39–51.
   Google Scholar
• Gold R, Schmied M, Giegerich G et al. Differentiation between cellular apoptosis and necrosis by the combined use of in situ tailing and nick translation techniques. Lab Invest 1994;71:219–25.
   PubMed Web of Science ®Google Scholar
• Viola A, Lanzavecchia A. T-cell activation determined by T-cell receptor number and tunable threshold. Science 1996;273:109–6.
   Google Scholar
• Linsley PS, Ledbetter JA. The role of the CD28 receptor during T-cell responses to antigen. Annu Rev Immunol 1993;11:191–212.
   PubMed Web of Science ®Google Scholar
• Andersson EC, Christensen JP, Marker 0, Thomsen AR. Changes in cell adhesion molecule expression on T cells associated with sytemic virus infection. 7 Immunol 1994;152: 1237–45.
   Google Scholar
• Rodrigues MM, Cordey AS, Arreaza G et al. CD8+ cytolytic T-cell clones derived against the Plasmodium yoelii circumsporozoite protein protect against malaria. Int Immunol 1991;3:579–85.
   PubMed Web of Science ®Google Scholar
• Rodrigues M, Nussenzweig R, Romero P, Zavala E The in vivo cytotoxic activity of CD8+ T-cell clones correlates with their levels of expression of adhesion molecules. 7 Exp Med 1992;175: 895–905.
   Google Scholar