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Expert Opinion on Pharmacotherapy Volume 22, 2021 - Issue 7
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Letter to the editor

Letter to editor – a response to: ‘efficacy and safety of triple combination therapy for treating chronic obstructive pulmonary disease: an expert review’

Neil C. Barnesa Respiratory Therapy Area, GlaxoSmithKline, Brentford, UK;b William Harvey Institute, Bart’s and the London School of Medicine and Dentistry, London, UKCorrespondence[email protected]
View further author information
,
Paul Jonesa Respiratory Therapy Area, GlaxoSmithKline, Brentford, UK;c Institute of Infection and Immunity, St George’s, University of London, London, UKView further author information
,
David A. Lipsond Clinical Sciences, GlaxoSmithKline, Collegeville, PA, USA;e Pulmonary, Allergy and Critical Care Division, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USAView further author information
,
Dave Singhf Centre for Respiratory Medicine and Allergy, Institute of Inflammation and Repair, Manchester Academic Health Science Centre, The University of Manchester, Manchester University NHS Foundation Trust, Manchester, UKView further author information
&
Fernando J. Martinezg Division of Pulmonary and Critical Care Medicine, New York-Presbyterian Hospital/Weill Cornell Medical Center, New York, NY, USAView further author information
Pages 939-941 | Published online: 30 Mar 2021

References

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  • Han MK, Criner GJ, Dransfield MT, et al. The effect of inhaled corticosteroid withdrawal and baseline inhaled treatment on exacerbations in the IMPACT study. A randomized, double-blind, multicenter clinical trial. Am J Respir Crit Care Med. 2020;202(9):1237–1243.
  • Lipson DA, Barnhart F, Brealey N, et al. Once-daily single-inhaler triple versus dual therapy in patients with COPD. N Engl J Med. 2018;378(18):1671–1680.
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  • Rabe KF, Martinez FJ, Ferguson GT, et al. Triple inhaled therapy at two glucocorticoid doses in moderate-to-very-severe COPD. N Engl J Med. 2020;383(1):35–48.
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  • Martinez FJ, Rabe KF, Ferguson GT, et al. Benefits of budesonide/glycopyrrolate/formoterol fumarate metered dose inhaler (BGF MDI) on symptoms and quality of life in patients with chronic obstructive pulmonary disease (COPD) in the ETHOS trial. Am J Respir Crit Care Med. 2020;201:A5073.
  • Rabe KF, Martinez FJ, Singh D, et al. Improvements in lung function with budesonide/glycopyrrolate/formoterol fumarate metered dose inhaler (BGF MDI) versus dual therapies in patients with COPD: a sub-study of the ETHOS trial. Am J Respir Crit Care Med. 2020;201:A5074.
  • Hartley BF, Barnes NC, Lettis S, et al. Risk factors for exacerbations and pneumonia in patients with chronic obstructive pulmonary disease: a pooled analysis. Respir Res. 2020;21(1):5.
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  • Vestbo J, Anderson JA, Brook RD, et al. Fluticasone furoate and vilanterol and survival in chronic obstructive pulmonary disease with heightened cardiovascular risk (SUMMIT): a double-blind randomised controlled trial. Lancet. 2016;387(10030):1817–1826.
  • Papi A, Vestbo J, Fabbri L, et al. Extrafine inhaled triple therapy versus dual bronchodilator therapy in chronic obstructive pulmonary disease (TRIBUTE): a double-blind, parallel group, randomised controlled trial. Lancet. 2018;391(10125):1076–1084.
  • Lipson DA, Barnacle H, Birk R, et al. FULFIL trial: once-daily triple therapy for patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2017;196(4):438–446.
  • European Medicines Agency (EMA). Pharmacovigilance risk assessment committee (PRAC), recommendation 2016. Inhaled corticosteroids (ICS) containing medicinal products indicated in the treatment of chronic obstructive pulmonary disease (COPD); 2016 [cited Nov 2020]. Available from: https://www.ema.europa.eu/medicines/human/referrals/inhaled-corticosteroids-containing-medicinal-products-indicated-treatment-chronic-obstructive

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