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Expert Opinion on Pharmacotherapy Volume 22, 2021 - Issue 13
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Editorial

How do you treat obesity in the elderly pharmacologically?

Claudio Daniel Gonzáleza Titular de Farmacología, CEMIC, Buenos Aires, ArgentinaView further author information
&
Guillermo Di Girolamob Titular Tercera Cá tedra de Farmacología, Universidad de Buenos Aires, Facultad de Medicina, Buenos Aires, Argentina;c del Instituto Alberto C. Taquini de Investigaciones en Medicina Traslacional (IATIMET), Universidad de Buenos Aires – CONICET, Facultad de Medicina, Buenos Aires, ArgentinaCorrespondence[email protected] [email protected]
ORCID Iconhttps://orcid.org/0000-0002-3904-8744View further author information
ORCID Icon
Pages 1639-1642 | Received 29 Jan 2021, Accepted 19 Apr 2021, Published online: 13 May 2021

References

  • Hales CM, Fryar CD, Carroll MD, et al. Trends in obesity and severe obesity prevalence in US youth and adults by sex and age, 2007-2008 to 2015-2016. JAMA. 2018;319(16):1723–1725.
  • Batsis JA, Zagaria AB. Addressing obesity in aging patients. Med Clin North Am. 2018;102(1):65–85.
  • Di Angelantonio E, Sn B, Wormser D, et al.; Global BMI Mortality Collaboration. Bodymass index and all-cause mortality: individual-participant-data meta-analysis of 239 prospective studies in four continents. Lancet. 2016;388(10046):776–786.
  • Batsis JA, Gill LE, Masutani RK, et al. Weight loss interventions in older adults with obesity: a systematic review of randomized controlled trials since 2005. J Am Geriatr Soc. 2017;65(2):257–268.
  • Normandin E, Chmelo E, LylesM. F, et al. Effect of resistance training and caloric restriction on the metabolic syndrome. Med Sci Sports Exerc. 2017;49(3):413–419.
  • Nicklas BJ, Chmelo E, Delbono O, et al. Effects of resistance training with and without caloric restriction on physical function and mobility in overweight and obese older adults: a randomized controlled trial. Am J Clin Nutr. 2015;101(5):991–999.
  • Villareal DT, Chode S, Parimi N, et al. Weight loss, exercise, or both and physical function in obese older adults. N Engl J Med. 2011;364(13):1218–1229.
  • Goisser S, Kiesswetter E, Schoene D, et al. Dietary weight-loss interventions for the management of obesity in older adults. Rev Endocr Metab Disord. 2020 Sep;21(3):355–368.
  • Kammire DE, Walkup MP, Ambrosius WT, et al. Effect of weight change following intentional weight loss on bone health in older adults with obesity. Obesity (Silver Spring). 2019;27(11):1839–1845.
  • Dvorak R, Starling RD, Calles-Escandon J, et al. Drug therapy for obesity in the elderly. Drugs Aging. 1997 Nov;II(5):338–351. I 17D-229X/97/001I −0338/S07.0010.
  • Haywood C, Sumithran P. Treatment of obesity in older persons—A systematic review. Obes Rev. 2019 Apr;20(4):588–598. Epub 2019 Jan 15.
  • Horie NC, Cercato C, Mancini MC, et al. Long-Term Pharmacotherapy for Obesity in Elderly Patients. Drugs Aging. 2010 Jun 1;27(6):497–506.
  • McKee A, Morley JE. Obesity in the elderly. Endotext 2018 Oct 12. In: Feingold KR, Anawalt B, Boyce A, et al., editors. Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000. PMID: 30379513 Bookshelf ID: NBK53253329.
  • Marso SP, Daniels GH, Brown-Frandsen K, et al.; Liraglutide and cardiovascular outcomes in type 2 diabetes.N. Engl J Med. 2016a;375:311–322.
  • Garvey WT, Mechanick JI, Brett EM, et al.; American association of clinical endocrinologists and American college of endocrinology comprehensive clinical practice guidelines for medical care of patients with obesity. Endocr Pract. 2016 Jul;22(Suppl 3):1–203.
  • Pi-Sunyer X, Astrup A, Fujioka K, et al.; A randomized, controlled trial of 3.0 mg of liraglutide in weight management. N Engl J Med. 2015 Jul 2;373(1):11–22.
  • Davies MJ, Bergenstal R, Bode B, et al.; NN8022-1922 Study Group. Efficacy of liraglutide for weight loss among patients with type 2 diabetes: the SCALE diabetes randomized clinical trial. JAMA. 2015 Aug 18;314(7):687–699
  • NN8022-1923 Investigators, Wadden TA, Hollander P, Klein S, et al. Weight maintenance and additional weight loss with liraglutide after low-calorie-diet-induced weight loss: the SCALE Maintenance randomized study. Int J Obes (Lond). 2015 Jan;39(1):187. Epub 2014 Oct 14.
  • Marso SP, Bain SC, Consoli A, et al., Semaglutide and cardiovascular outcomes in patients with type 2 diabetes. N Engl J Med. 2016 Nov 10;375(19):1834–1844. Epub 2016 Sep 15.
  • Sheu WHH, Chan SP, Matawaran BJ, et al. Use of SGLT-2 inhibitors in patients with type 2 diabetes mellitus and abdominal obesity: an Asian perspective and expert recommendations. Diabetes Metab J. 2020 Feb;44(1):11–32.
  • Baggio LL, Drucker DJ. Glucagon-like peptide-1 receptor co-agonists for treating metabolic disease. Mol Metab. 2020 Sep;25:101090.
  • Williams DM, Nawaz A, Evans M. Drug therapy in obesity: a review of current and emerging treatments. Diabetes Ther. 2020 Jun;11(6):1199–1216. Epub 2020 Apr 15.

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