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Articles

Constipation prevalence and fatigue severity in regular kratom (Mitragyna speciosa Korth.) users

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Pages 233-239 | Received 22 May 2018, Accepted 28 Oct 2018, Published online: 03 Dec 2018

References

  • Anwar, M., Law, R., & Schier, J. (2016). Notes from the field: Kratom (Mitragyna speciosa) exposures reported to poison centers-United States, 2010-2015. CDC, 65(29), 748–749.
  • Assanangkornchai, S., Muekthong, A., Sam-Angsri, N., & Pattanasattayawong, U. (2007). The use of mitragynine speciosa (“Krathom”), an addictive plant, in Thailand. Substance Use & Misuse, 42(14), 2145–2157. doi:10.1080/10826080701205869
  • Bawor, M., Bami, H., Dennis, B. B., Plater, C., Worster, A., Varenbut, M., … Samaan, Z. (2015). Testosterone suppression in opioid users: A systematic review and meta-analysis. Drug & Alcohol Dependence, 149, 1–9. doi:10.1016/j.drugalcdep.2015.01.038
  • Bell, T. J., Panchal, S. J., Miaskowski, C., Bolge, S. C., Milanova, T., & Williamson, R. (2009). The prevalence, severity, and impact of opioid-induced bowel dysfunction: Results of a US and European Patient Survey (PROBE 1). Pain Medicine, 10, 35–42. doi:10.1111/j.1526-4637.2008.00495.x
  • Chittrakarn, S., Sawangjaroen, K., Prasettho, S., Janchawee, B., & Keawpradub, N. (2008). Inhibitory effects of kratom leaf extract (Mitragyna speciosa Korth.) on the rat gastrointestinal tract. Journal of Ethnopharmacology, 116, 173–178. doi:10.1016/j.jep.2007.11.032
  • Griffin, O. H., & Webb, M. E. (2017). The scheduling of kratom and selective use of data. Journal of Psychoactive Drugs, 50(5), 1–7.
  • Grundmann, O. (2017). Patterns of kratom use and health impact in the US-Results from an online survey. Drug and Alcohol Dependence, 176, 63–70. doi:10.1016/j.drugalcdep.2017.03.007
  • Hemby, S. E., McIntosh, S., Leon, F., Cutler, S. J., & McCurdy, C. R. (2018). Abuse liability and therapeutic potential of the Mitragyna speciosa (kratom) alkaloids mitragynine and 7-hydroxymitragynine. Addiction Biology, 21(1), 98-110.
  • Henningfield, J. E., Fant, R. V., & Wang, D. W. (2017). The abuse potential of kratom according the 8 factors of the controlled substances act: Implications for regulation and research. Psychopharmacology, 235(2): 573-589.
  • Kapp, F. G., Maurer, H. H., Auwärter, V., Winkelmann, M., & Hermanns-Clausen, M. (2011). Intrahepatic cholestasis following abuse of powdered kratom (Mitragyna speciosa). Journal of Medical Toxicology, 7(3), 227–231. doi:10.1007/s13181-011-0155-5
  • Katz, N., & Mazer, N. A. (2009). The impact of opioids on the endocrine system. The Clinical Journal of Pain, 25(2), 170–175. doi:10.1097/AJP.0b013e3181850df6
  • Kronstrand, R., Roman, M., Thelander, G., & Eriksson, A. (2011). Unintentional fatal intoxications with mitragynine and O-Desmethyltramadol from the herbal blend krypton. Journal of Analytical Toxicology, 35, 242–247.
  • Kruegel, A. C., Gassaway, M. M., Kapoor, A., Varadi, A., Majumdar, S., Filizola, M., … Sames, D. (2016). Synthetic and receptor signaling exploration of the Mitragyna alkaloids: Mitragynine as an atypical molecular framework for opioid receptor modulators. Journal of the American Chemical Society, 138, 6754–6764. doi:10.1021/jacs.6b00360
  • Kruegel, A. C., & Grundmann, O. (2017). The medicinal chemistry and neuropharmacology of kratom: A preliminary discussion of a promising medicinal plant and analysis of its potential for abuse. Neuropharmacology, 134, 108-120.
  • Krupp, L.B., LaRocca, N. G., Muir-Nash, J., & Steinberg, A. D. (1989). The fatigue severity scale application to patients with multiple sclerosis and systemic lupus erythematosus. Archives Of Neurology, 46, 1121-1123.
  • Matsumoto, K., Hatori, Y., Murayama, T., Tashima, K., Wongseripipatana, S., Misawa, K., … Horie, S. (2006). Involvement of μ-opioid receptors in antinociception and inhibition of gastrointestinal transit induced by 7-hydroxymitragynine, isolated from Thai herbal medicine Mitragyna speciosa. European Journal of Pharmacology, 549, 63–70. doi:10.1016/j.ejphar.2006.08.013
  • Matsumoto, K., Takayama, H., Narita, M., Nakamura, A., Suzuki, M., Suzuki, T., … Horie, S. (2008). MGM-9 [(E)-methyl 2-(3-ethyl-7a,12a-(epoxyethanoxy)-9-fluoro-1,2,3,4,6,7,12,12b-octahydro-8-methoxyindolo[2,3-a]quinolizin-2-yl)-3-methoxyacrylate], a derivative of the indole alkaloid mitragynine: A novel dual acting μ- and κ-opioid agonist with potent antinociceptive and weak rewarding effects in mice. Neuropharmacology, 55, 154–165. doi:10.1016/j.neuropharm.2008.05.003
  • McMillan, S.C., & Williams, F.A. (1989). Validity and reliability of the constipation assessment scale. Cancer Nursing, 12(3), 183–8.
  • Panchal, S. J., Müller‐Schwefe, P. J. I. W., & Wurzelmann, J. I. (2007). Opioid‐induced bowel dysfunction: Prevalence, pathophysiology and burden. International Journal of Clinical Practice, 61(7), 1181–1187. doi:10.1111/j.1742-1241.2007.01415.x
  • Pinney Associates. (2016). Assessment of kratom under the CSA eight factors and scheduling recommendation. Retrieved from http://www.pinneyassociates.com/wp-content/uploads/2017/07/Kratom-8-Factor-by-PinneyAssoc-11.28.16.pdf
  • Prozialeck, W. C. (2016). Update on the pharmacology and legal status of kratom. The Journal Of The American Osteopathic Association, 116(12), 802-809.
  • Rajagopal, A., Vassilopoulou‐Sellin, R., Palmer, J. L., Kaur, G., & Bruera, E. (2004). Symptomatic hypogonadism in male survivors of cancer with chronic exposure to opioids. Cancer, 100(4), 851–858. doi:10.1002/cncr.20028
  • Saingam, D., Assanangkornchai, S., Geater, A. F., & Balthip, Q. (2012). Pattern and consequences of krathom (Mitragyna speciosa Korth.) use among male villagers in southern Thailand: A qualitative study. International Journal of Drug Policy, 24(4), 351–358. doi:10.1016/j.drugpo.2012.09.004
  • Singh, D., Müller, C. P., Murugaiyah, V., Hamid, S. B. S., Vicknasingam, B. K., Avery, B., … Mansor, S. M. (2018a). Evaluating the hematological and clinical-chemistry parameters of kratom (Mitragyna speciosa) users in Malaysia. Journal of Ethnopharmacology, 214, 197–206. doi:10.1016/j.jep.2017.12.017
  • Singh, D., Müller, C. P., & Vicknasingam, B. K. (2014). Kratom (Mitragyna speciosa) dependence, withdrawal symptoms and craving in regular users. Drug & Alcohol Dependence, 139, 132–137. doi:10.1016/j.drugalcdep.2014.03.017
  • Singh, D., Müller, C. P., Vicknasingam, B. K., & Mansor, S. M. (2015). Social functioning of Kratom (Mitragyna speciosa) users in Malaysia. Journal of Psychoactive Drugs, 47(2), 125–131. doi:10.1080/02791072.2015.1012610
  • Singh, D., Murugaiyah, V., Hamid, S. B. S., Kasinather, V., Chan, M. S. A., Ho, E. T. W., … Mansor, S. M. (2018b). Assessment of gonadotropins and testosterone hormone levels in regular Mitragyna speciosa (Korth.) users. Journal of Ethnopharmacology, 221, 30–36. doi:10.1016/j.jep.2018.04.005
  • Singh, D., Narayanan, S., & Vicknasingam, B. (2016). Traditional and non-traditional uses of Mitragynine (Kratom): A survey of the literature. Brain Research Bulletin, 126, 41–46. doi:10.1016/j.brainresbull.2016.05.004
  • Singh, D., Narayanan, S., Vicknasingam, B. K., Prozialeck, W. C., Ramanathan, S., Zainal, H., & Harun, S. N. (2018c). Severity of pain and sleep problems during Kratom (Mitragyna speciosa Korth.) cessation among regular Kratom users. Journal of Psychoactive Drugs, 1–9. doi:10.1080/02791072.2018.1511879
  • Smith, H. S., & Elliott, J. A. (2012). Opioid-induced androgen deficiency (OPIAD). Pain Physician, 15(Supplement 3), ES145–56.
  • Suwanlert, S. (1975). A study of kratom eaters in Thailand. Bulletin on Narcotics, 27(3), 21–27.
  • Vallerand, A. H. (2017). Opioid-induced Constipation. The Journal for Nurse Practitioners, 13(2), 170–174. doi:10.1016/j.nurpra.2016.11.006
  • Varadi, A., Marrone, G. F., Palmer, T. C., Narayan, A., Szabo, M. R., Rouzic, V. L., … Majumdar, S. (2016). Mitragynine/corynantheidine pseudoindoxyls as opioid analgesic with Mu Agoism and Delta Antagonism, which do not recruit β-Arrestin-2. Journal of Medical Chemistry, 59(18), 8381–8397. doi:10.1021/acs.jmedchem.6b00748
  • Vicknasingam, B., Narayanan, S., Beng, G. T., & Mansor, S. M. (2010). The informal use of ketum (Mitragyna speciosa) for opioid withdrawal in the northern states of peninsular Malaysia and implications for drug substitution therapy. International Journal of Drug Policy, 21, 283–288. doi:10.1016/j.drugpo.2009.12.003
  • Yue, K., Kopajtic, T. A., & Katz, J. L. (2018). Abuse liability of mitragynine assessed with a self-administration procedure in rats. Psychopharmacology. doi:10.1007/s00213-018-4974-9

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