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Research Article

Motor unit number estimation (MUNE): how may it contribute to the diagnosis of ALS?

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Pages S41-S44 | Published online: 10 Jul 2009

References

  • Brooks BR. El Escorial World Federation of Neurology criteria for the diagnosis of amyotrophic lateral sclerosis. Sub- committee on Motor Neuron Diseases/Amyotrophic Lateral Sclerosis of the World Federation of Neurology Research Group on Neuromuscular Diseases and the El Escorial ‘Clinical limits of amyotrophic lateral sclerosis’ workshop con- tributors. J Neurol Sci 1994; 124 (suppl): 96–107.
  • Brooks BR, Miller RG, Swash M, Munsat TL and Airlie House ‘Current Issues in ALS Therapeutic Trials’ Workshop Contrib- utors (1998). El Escorial Revisited: Revised Criteria for the Diagnosis of Amyotrophic Lateral Sclerosis, http://www.wfnals.org/Articles/elescorial1998.htm.
  • Olney RK, Yuen EC, Engstrom JW. Statistical motor unit number estimation: reproducibility and sources of error in patients with amyotrophic lateral sclerosis. Muscle Nerve 2000; 23: 193–197.
  • Lomen-Hoerth C, Olney RK. A comparison of multiple point and statistical motor unit number estimation (MUNE). Muscle Nerve 2000; (In press).
  • Felice KJ. A longitudinal study comparing thenar motor unit number estimates to other quantitative tests in patients with amyotrophic lateral sclerosis. Muscle Nerve 1997; 20: 179–185.
  • Yuen EC, Olney RK. Longitudinal study of fiber density and motor unit number estimate in patients with amyotrophic lateral sclerosis. Neurology 1997; 94: 573–578.
  • Olney RK, Yuen EC, Engstrom JE. The rate of change in motor unit number estimates predicts survival in patients with amyotrophic lateral sclerosis (ALS). Neurology 1999; 52 (Suppl 2): A3.

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