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Amyotrophic Lateral Sclerosis and Other Motor Neuron Disorders Volume 1, 2000 - Issue 3
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Research Article

The skin in amyotrophic lateral sclerosis

Seiitsu Ono Department of Neurology, Teikyo University School of Medicine, Ichihara Hospital, Japan
Pages 191-199 | Published online: 10 Jul 2009

  • Brown RH Jr. Amyotrophic lateral sclerosis. Insights from genetics. Arch Neurol 1997; 54: 1246-1250.
  • Toyokura Y. A remarkable absence of decubitus formation in patients with amyotrophic lateral sclerosis. Neurol Med Chir (Tokyo) 1975; 2: 215-217.
  • Furukawa T, Toyokura Y. Amyotrophic lateral sclerosis and bedsores. Lancet 1976; i: 862.
  • Uebayashi Y, Yase Y, Tanaka H, Shimada Y, Toyokura Y. Prognosis of motor neuron disease in Japan. Neuroepidemiology 1983; 2: 243-256.
  • Ono S, Toyokura Y, Mannen T, Ishibashi Y. 'Delayed return phenomenon' in amyotrophic lateral sderosis. Acta Neurol Scand 1988; 77: 102-107.
  • Fullmer HM, Sedler HD, Krooth RS, Kurland LT. A cutaneous disorder of connective tissue in amyotrophic lateral sderosis: a histochemical study. Neurology 1960; 10: 717-724.
  • Unsworth DJ, Scott DL, Almond TJ, Beard HK, Holborow EJ, Walton KW. Studies on reticulin. I. Serological and immunohistological investigation of the occurrence of collagen type III, fibronectin and the non-collagenous glycoprotein of Pras and Clynn in reticulin. Br J Exp Pathol 1982; 63: 154-166.
  • Fleischmajer R, Cay S, Meigel WN, Perlish JS. Collagen in the cellular and fibrotic stages of scleroderma. Arthritis Rheum 1978; 21: 418-428.
  • Kischer CW, Shetlar MR Collagen and mucopolysaccharides in the hypertrophie scar. Connect Tissue Res 1974; 2: 205-213.
  • Groniowska M, Dabrowski J, Maciejewski W, Walski M. Electron-microscopic evaluation of collagen fibrils after topical corticosteroid therapy. Dermatologica 1976; 152 (suppl): 147-153.
  • Kischer CW, Shetler MR. Collagen and mucopolysaccharides in the hypertrophie scar. Connect Tissue Res 1974; 2: 205-213.
  • Wood CC. The formation of fibrils from collagen solutions. III. Effect of chondroitin sulphate and some other naturally occurring polyanions on the rate of formation. Biochem J 1960; 75: 605-612.
  • Ross R, Benditt EP. Wound healing and collagen formation. II. Fine structure in experimental study. J Cell Biol 1962; 12: 533-551.
  • Kobayashi T, Asboe-Hansen C. Ultrastructural changes in the inflammatory zone of localized sderoderma. Acta Derm Venereol (Stockholm) 1974; 54: 105-112.
  • Ono S, Toyokura Y, Mannen T, Ishibashi Y. Amyotrophic lateral sclerosis: Histological, histochemical, and ultrastructural abnormalities of skin. Neurology 1986; 36: 948-956.
  • Forrest L, Dixon J, Jackson DS. Comparative studies on the insoluble collagens of guinea-pig dermis and dermal scar tissue. Connect Tissue Res 1972; 1: 243-250.
  • Ono S, Mannen T, Toyokura Y. Differential diagnosis between amyotrophic lateral sclerosis and spinal muscular atrophy by skin involvement J Neurol Sci 1989; 91: 301-310.
  • Provinciali L, Cangiotti A, Tulli D, Carboni V, Cinti S. Skin abnormalities and autonomie involvement in the early stage of amyotrophic lateral sclerosis. J Neurol Sci 1994; 126: 54-61.
  • Ono S, Mechanic GL, Yamauchi M. Amyotrophic lateral sderosis: unusually low content of collagen in skin. J Neurol Sci 1990; 100: 234-237.
  • Ono S, Yamauchi M. Amyotrophic lateral sclerosis: Increased solubility of skin collagen. Neurology 1992; 42: 1535-1539.
  • Ono S, Yamauchi M. Collagen cross-linking of skin in patients with amyotrophic lateral sclerosis. Ann Neurol 1992; 31: 305-310.
  • Eyre DR, Paz MA, Gallop PM. Cross-linking in collagen and elastin. Ann Rev Biochem 1984; 53: 717-748.
  • Yamauchi M, London RE, Guenat C, Hashimoto F, Mechanic CL Structure and formation of a stable histidine-based trifunctional cross-link in skin collagen. J Biol Chem 1987; 262: 11428-11434.
  • Bailey AJ, Robins SP, Balian C. Biological significance of the intermolecular crosslinks of collagen. Nature 1974; 251: 105-109.
  • Robins SP. Analysis of the cross-linking components in collagen and elastin. Meth Biochem Anal 1982; 28: 329-379.
  • Yamauchi M, Woodley DT, Mechanic CL. Aging and crosslinking of skin collagen. Biochem Biophys Res Commun 1988; 152: 898-903.
  • Nimni ME, Harkness RD. Molecular structures and functions of collagen. In: Nimni ME, ed. Collagen. VoI 1. Biochemistry. Boca Raton, FL CRC Press, 1988: 1-77.
  • Yamauchi M, Young DR, Chandler GS, Mechanic CL. Crosslinking and new bone collagen synthesis in immobilized and recovering primate osteoporosis. Bone 1988; 9: 415-418.
  • Bornstein P, Sage H. Structurally distinct collagen types. Ann Rev Biochem 1980; 49: 957-1003.
  • Ono S, Imai T, Takahashi K, et al. Decreased type IV collagen of skin and serum in patients with amyotrophic lateral sclerosis. Neurology 1998; 51: 114-120.
  • Ono S, Imai T, Matsubara S, et al. Decreased urinary concentrations of type IV collagen in amyotrophic lateral sclerosis. Acta Neurol Scand 1999; 100: 111-116.
  • Fullmer HM, Gibson WA, Lazarus C, Stam AC Jr. CoIlagenolytic activity of the skin associated with neuromuscular diseases including amyotrophic lateral sclerosis. Lancet 1966; i: 1007-1009.
  • Fullmer HM, Lazarus GS, Stam AC Jr, Gibson WA. Collagenase in neuromuscular diseases. In: Morris FH, Kurland LT, eds. Motor Neuron Disease. New York Grune Stratton, 1969: 242-251.
  • Beach RL, Rao JS, Festoff BW, Reyes ET, Yanagihara R, Cajdusek DC. Collagenase activity in skin fibroblasts of patients with amyotrophic lateral sclerosis. J Neurol Sci 1986; 72: 49-60.
  • Chersetich I, Lord T, Campanile C, Grappone C, Dini C. Hyaluronic acid in cutaneous intrinsic aging. Int J Dermatol 1994; 33: 119-122.
  • Ono S, Nagao K, Yamauchi M. Amorphous material of the skin in amyotrophic lateral sclerosis: A morphologic and biochemical study. Neurology 1994; 44: 537-540.
  • Ono S, Imai T, Yamauchi M, Nagao K Hyaluronic acid is increased in the skin and urine in patients with amyotrophic lateral sclerosis. J Neurol 1996; 243: 693-699.
  • Ono S, Imai T, Yamano T, Shimizu N, Nagao K. Alterations of skin glycosaminoglycans in patients with ALS. Neurology 1998; 51: 399-404.
  • Joachim CL, Mori H, Selkoe DJ. Amyloid ß-protein deposition in tissues other than brain in Alzheimer's disease. Nature 1989; 341: 226-230.
  • Kolde C, Bachus R, Ludolph A. Skin involvement in amyotrophic lateral sclerosis. Lancet 1996; 347: 1226-1227.
  • Ono S, Matsuno S, Shimizu N, Shoji S, Tamaoka A. Amyloid ß°rotein in skin of patients with amyotrophic lateral sclerosis. Lancet 1998; 351: 956-957.
  • Mahoney H, Barthel DW. Functional evaluation: the Barthel index. Maryland State Med J 1965; 14: 61-65.

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