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Original Research

Reduced p75NTR expression delays disease onset only in female mice of a transgenic model of familial amyotrophic lateral sclerosis

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Pages 100-105 | Received 14 Oct 2002, Accepted 03 Feb 2003, Published online: 10 Jul 2009

References

  • Rosen DR, Siddique T, Patterson D, Figlewicz DA, Sapp P, Hentati A et al. Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis. Nature 1993; 362(6415): 59–62.
  • Gurney ME, Pu H, Chiu AY, Dal Canto MC, Polchow CY, Alexander DD et al. Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation. Science 1994; 264(5166): 1772–1775.
  • Henderson CE, Camu W, Mettling C, Gouin A, Poulsen K, Karihaloo M et al. Neurotrophins promote motor neuron survival and are present in embryonic limb bud. Nature 1993; 363(6426): 266–270.
  • Piehl F, Frisen J, Risling M, Hokfelt T, Cullheim S. Increased trkB mRNA expression by axotomized motoneurones. Neuroreport 1994; 5(6): 697–700.
  • Seeburger JL, Tarras S, Natter H, Springer JE. Spinal cord motoneurons express p75NGFR and p145trkB mRNA in amyotrophic lateral sclerosis. Brain Res 1993; 621(1): 111–115.
  • Nishio T, Sunohara N, Furukawa S. Neurotrophin switching in spinal motoneurons of amyotrophic lateral sclerosis. Neuro- report 1998; 9(7): 1661–1665.
  • Xu H, Federoff H, Maragos J, Parada LF, Kessler JA. Viral transduction of trkA into cultured nodose and spinal motor neurons conveys NGF responsiveness. Dev Biol 1994; 163(1): 152–161.
  • Yan Q, Johnson EM Jr. An immunohistochemical study of the nerve growth factor receptor in developing rats. J Neurosci 1988; 8(9): 3481–3498.
  • Ferri CC, Moore FA, Bisby MA. Effects of facial nerve injury on mouse motoneurons lacking the p75 low-affinity neurotrophin receptor. J Neurobiol 1998; 34(1): 1–9.
  • Koliatsos VE, Crawford TO, Price DL. Axotomy induces nerve growth factor receptor immunoreactivity in spinal motor neurons. Brain Res 1991; 549(2): 297–304.
  • Lowry KS, Murray SS, McLean CA, Talman P, Mathers S, Lopes EC et al. A potential role for the p75 low-affinity neurotrophin receptor in spinal motor neuron degeneration in murine and human amyotrophic lateral sclerosis. Amyotroph Lateral Scler Other Motor Neuron Disord 2001; 2(3): 127–134.
  • Yan Q, Snider WD, Pinzone JJ, Johnson EM Jr. Retrograde transport of nerve growth factor (NGF) in motoneurons of developing rats: assessment of potential neurotrophic effects. Neuron 1988; 1(4): 335–343.
  • Miller FD, Kaplan DR. Life and death decisions: a biological role for the p75 neurotrophin receptor. Cell Death Differ 1998; 5(5): 343–345.
  • Lee KF, Li E, Huber LJ, Landis SC, Sharpe AH, Chao MV et al. Targeted mutation of the gene encoding the low affinity NGF receptor p75 leads to deficits in the peripheral sensory nervous system. Cell 1992; 69(5): 737–749.
  • Hall ED, Oostveen JA, Gurney ME. Relationship of microglial and astrocytic activation to disease onset and progression in a transgenic model of familial ALS. Glia 1998; 23(3): 249–256.
  • Morrison BM, Janssen WG, Gordon JW, Morrison JH. Time course of neuropathology in the spinal cord of G86R super- oxide dismutase transgenic mice. J Comp Neurol 1998; 391(1): 64–77.
  • Oderfeld-Nowak B, Zaremba M, Micera A, Aloe L. The upregulation of nerve growth factor receptors in reactive astrocytes of rat spinal cord during experimental autoimmune encephalomyelitis. Neurosci Lett 2001; 308(3): 165–168.
  • Wiese S, Metzger F, Holtmann B, Sendtner M. The role of p75NTR in modulating neurotrophin survival effects in devel- oping motoneurons. Eur J Neurosci 1999; 11(5): 1668–1676.
  • Lowry KS, Murray SS, Coulson EJ, Epa R, Bartlett PF, Barrett G et al. Systemic administration of antisense p75(NTR) oligo- deoxynucleotides rescues axotomised spinal motor neurons. J Neurosci Res 2001; 64(1): 11–17.
  • Trieu VN, Uckun FM. Genistein is neuroprotective in murine models of familial amyotrophic lateral sclerosis and stroke. Biochem Biophys Res Commun 1999; 258(3): 685–688.
  • Jezierski MK, Sohrabji F. Region- and peptide-specific regulation of the neurotrophins by estrogen. Brain Res Mol Brain Res 2000; 85(1–2): 77–84.
  • Junier MP, Suzuki F, Onteniente B, Peschanski M. Target- deprived CNS neurons express the NGF gene while reactive glia around their axonal terminals contain low and high affinity NGF receptors. Brain Res Mol Brain Res 1994; 24(1–4): 247–260.
  • Garcia-Segura LM, Naftolin F, Hutchison JB, Azcoitia I, Chowen JA. Role of astroglia in estrogen regulation of synaptic plasticity and brain repair. J Neurobiol 1999; 40(4): 574–584.
  • McCarthy JB, Barker-Gibb AL, Alves SE, Milner TA. TrkA immunoreactive astrocytes in dendritic fields of the hippocampal formation across estrous. Glia 2002; 38(1): 36–44.

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