23
Views
5
CrossRef citations to date
0
Altmetric
Original article

Biochemical characterization of plasma in amyotrophic lateral sclerosis: Amino acid and protein composition

, , , , , & show all
Pages 104-110 | Received 11 Aug 2004, Accepted 15 Dec 2005, Published online: 20 Apr 2012

References

  • Bruijn LI, Miller TM, Cleveland DW. Unravelling the mechanisms involved in motor neuron degeneration in ALS. Annu Rev Neurosci. 2004;27:723–49.
  • Malaspina A, Kaushik N, de Belleroche J. Differential expression of 14 genes in amyotrophic lateral sclerosis spinal cord detected using gridded cDNA arrays. J Neurochem. 2001;77:132–45.
  • Yoshihara T, Ishigaki S, Yamamoto M, Liang Y, Niwa J, Takeuchi H, et al. Differential expression of inflammation and apoptosis related genes in spinal cords of a mutant SOD1 transgenic mouse model of familial amyotrophic lateral sclerosis. J Neurochem. 2002;80:158–67.
  • Perry TL, Krieger C, Hansen S, Tabatabaei A. Amyotrophic lateral sclerosis: fasting plasma levels of cysteine and inorganic sulfate are normal, as are brain contents of cysteine. Neurology. 1991;41:487–90.
  • Camu W, Billiard M, Baldy-Moulinier M. Fasting plasma and CSF amino acid levels in amyotrophic lateral sclerosis: a subtype analysis. Acta Neurol Scand. 1993;88:51–5.
  • Garrel C, Faure H, Favier A, Besson G. Decrease of plasma cysteine values in sporadic amyotrophic lateral sclerosis patients could be the early event leading to an oxidative stress. ALS Other Motor Neuron Disord. 2001; 2(Suppl 2):132–3.
  • Ilzecka J, Stelmasiak Z, Solski J, Wawrzycki S, Szpetnar M. Plasma amino acids percentages in amyotrophic lateral sclerosis patients. Neurol Sci. 2003;24:293–5.
  • Ikeda J, Kohriyama T, Nakamura S. Elevation of serum soluble E-selectin and antisulfoglucuronyl paragloboside antibodies in amyotrophic lateral sclerosis. Eur J Neurol. 2000;7:541–7.
  • Almer G, Teismann P, Stevic Z, Halaschek-Wiener J, Deecke L, Kostic V, Przedborski S. Increased levels of the pro-inflammatory prostaglandin PGE2 in CSF from ALS patients. Neurology. 2002;58:1277–9.
  • Wilms H, Sievers J, Dengler R, Bufler J, Deuschl G, Lucius R. Intrathecal synthesis of monocyte chemoattractant protein-1 (MCP-1) in amyotrophic lateral sclerosis: further evidence for microglial activation in neurodegeneration. J Neuroimmunol. 2003;144:139–42.
  • Su¨ ssmuth SD, Tumani H, Ecker D, Ludolph AC. Amyotrophic lateral sclerosis: disease stage related changes of tau protein and S100 beta in cerebrospinal fluid and creatine kinase in serum. Neurosci Lett. 2003:57–60.
  • Norgren N, Rosengren L, Stigbrand T. Elevated neurofila- ment levels in neurological diseases. Brain Res. 2003; 987:25–31.
  • Beuche W, Yushchenko M, Mader M, Maliszewska M, Felgenhauer K, Weber F. Matrix metalloproteinase-9 is elevated in serum of patients with amyotrophic lateral sclerosis. Neuroreport. 2000;11:3419–22.
  • Ranganathan S, Jordan K, Sathanoori R, Henry S, Wood P, Urbinelli L, et al. Identification of ALS specific biomarkers by protein profiling of cerebral spinal fluid. ALS and Other Motor Neuron Disord. 2003; 4(Suppl 1):12.
  • Brooks BR, Miller RG, Swash M, Munsat TL. El Escorial revisited: revised criteria for the diagnosis of amyotrophic lateral sclerosis. ALS and Other Motor Neuron Disord. 2000;1:293–300.
  • Sottrup-Jensen L. Alpha-macroglobulins: structure, shape, and mechanism of proteinase complex formation. J Biol Chem. 1989;264:11539–42.
  • Black JA, Dixon GH. Amino-acid sequence of alpha chains of human haptoglobins. Nature. 1968;218:736–41.
  • Langlois MR, Delanghe JR. Biological and clinical signifi- cance of haptoglobin polymorphism in humans. Clinical Chemistry. 1996;42:1589–600.
  • Orrell R, Lane J, Ross M. Antioxidant treatment for amyotrophic lateral sclerosis/motor neuron disease. Cochrane Database Syst. Rev. 2004; CD002829.
  • Ilzecka J, Stelmasiak Z, Solski J, Wawrzycki S, Szpetnar M. Effect of riluzole (Rilutek) treatment on plasma amino acid percentages in amyotrophic lateral sclerosis patients. Neurol Sci. 2003;24:290–2.
  • Enghild JJ, Salvesen G, Brew K, Nagase H. Interaction of human rheumatoid synovial collagenase (matrix metallopro- teinase 1) and stromelysin (matrix metalloproteinase 3) with human alpha 2-macroglobulin and chicken ovostatin. Binding kinetics and identification of matrix metalloproteinase clea- vage sites. J Biol Chem. 1989;264:8779–85.
  • Yushchenko M, Weber F, Mader M, Scholl U, Maliszewska M, Tumani H, et al. Matrix metalloproteinase- 9 (MMP-9) in human cerebrospinal fluid (CSF): elevated levels are primarily related to CSF cell count. J Neuroimmunol. 2000;110:244–51.
  • Kovacs DM. Alpha 2-macroglobulin in late-onset Alzheimer’s disease. Experimental Gerontology. 2000;35:473–9.
  • Adachi N, Shoji S. Studies of protease inhibitors in the sera of patients with amyotrophic lateral sclerosis. J Neurol Sci. 1989;89:165–8.
  • Festoff BW. Occurrence of reduced alpha 2-macroglobulin and lowered protease inhibiting capacity in plasma of amyotrophic lateral sclerosis patients. Ann N Y Acad Sci. 1983;421:369–76.
  • Giometto B, Argentiero V, Sanson F, Ongaro G, Tavolato B. Acute-phase proteins in Alzheimer’s disease. Eur Neurol. 1988;28:30–3.
  • John HA, Purdom IF. Elevated plasma levels of haptoglobin in Duchenne muscular dystrophy: electrophoreticvariants in patients with a severe form of the disease. Electrophoresis. 1989;10:489–93.
  • Cucullo L, Marchi N, Marroni M, Fazio V, Namura S, Janigro D. Blood-brain barrier damage induces release of (alpha) 2-macroglobulin. Mol Cell Proteomics. 2003;2:234–41.
  • Finne J. Carbohydrate units of nervous tissue glycopro- teins. In: Montreuil J, Vliegenthart JFG, Schachter H, editors. Glycoproteins II. Amsterdam: Elsevier, 1997: pp.55–67.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.