417
Views
70
CrossRef citations to date
0
Altmetric
SHORT REPORT

Cannabinol delays symptom onset in SOD1 (G93A) transgenic mice without affecting survival

, , , , &
Pages 182-184 | Received 29 Sep 2004, Accepted 12 Jan 2005, Published online: 10 Jul 2009

References

  • Rowland L. P., Shneider N. A. Amyotrophic lateral sclerosis. N Engl J Med 2001; 344: 1688–700
  • Brujin L. I., Miller T. M., Cleveland D. W. Unraveling the mechanisms involved in motor neuron degeneration in ALS. Annu Rev Neurosci 2004; 27: 723–49
  • Carter G. T., Krivickas L. S., Weydt P., Weiss M. D., Miller R. G. Drug therapy for amyotrophic lateral sclerosis: where are we now?. IDrugs 2003; 6: 147–53
  • Carter G. T., Weydt P. Cannabis: old medicine with new promise for neurological disorders. Curr Opin Investig Drugs 2002; 3: 437–40
  • Carter G. T., Rosen B. S. Marijuana in the management of amyotrophic lateral sclerosis. Am J Hosp Palliat Care 2001; 18: 264–70
  • Aiken C. T., Tobin A. J., Schweitzer E. S. A cell‐based screen for drugs to treat Huntington's disease. Neurobiol Dis 2004; 16: 546–55
  • Gelinas D., Miller R. G., Abood M. E. A pilot study of safety and tolerability of Delta 9‐THC (Marinol) treatment for ALS. Amyotroph Lateral Scler Other Motor Neuron Disord 2002; 3((Suppl. 1))23
  • Amtmann D., Weydt P., Johnson K. L., Jensen M. P., Carter G. T. Survey of cannabis use in patients with amyotrophic lateral sclerosis. Am J Hosp Palliat Care 2004; 21: 95–104
  • Raman C., McAllister S. D., Rizvi G., Patel S. G., Moore D. H., Abood M. E. Amyotrophic lateral sclerosis: delayed disease progression in mice by treatment with a cannabinoid. Amyotroph Lateral Scler Other Motor Neuron Disord 2004; 5: 33–9
  • Witting A., Weydt P., Hong S., Kliot M., Moller T., Stella N. Endocannabinoids accumulate in spinal cord of SOD1 transgenic mice. J Neurochem 2004; 89: 1555–7
  • Gurney M. E., Pu H., Chiu A. Y., Dal Canto M. C., Polchow C. Y., Alexander D. D., et al. Motor neuron degeneration in mice that express a human Cu/Zn superoxide dismutase mutation. Science 1994; 264: 1772–5
  • Weydt P., Hong S. Y., Kliot M., Moller T. Assessing disease onset and progression in the SOD1 mouse model of ALS. Neuroreport 2003; 14: 1051–4

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.