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Expert Opinion on Biological Therapy Volume 22, 2022 - Issue 7
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Editorial

Brolucizumab in polypoidal choroidal vasculopathy

Ashish Sharmaa Lotus Eye Hospital and Institute, Coimbatore, IndiaCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-8550-9791View further author information
ORCID Icon,
Nikulaa Parachurib Department of Vitreoretina, Sankara Eye Hospital, Coimbatore, IndiaView further author information
,
Nilesh Kumarc Madhavi Netralaya, Ara, IndiaORCID Iconhttps://orcid.org/0000-0002-7439-2081View further author information
ORCID Icon,
Baruch D Kuppermannd Gavin Herbert Eye Institute, University of California, Irvine, CA, USAView further author information
,
Anat Loewensteine Division of Ophthalmology, Tel Aviv Medical, Tel Aviv University, IsraelView further author information
&
Francesco Bandellof Scientific Institute San Raffaele, University Vita-Salute, Milano, ItalyORCID Iconhttps://orcid.org/0000-0003-3238-9682View further author information
ORCID Icon
Pages 809-812 | Received 14 Mar 2022, Accepted 22 Jun 2022, Published online: 27 Jun 2022

References

  • Dugel PU, Singh RP, and Koh A, et al. HAWK and HARRIER: ninety-six-week outcomes from the phase 3 trials of brolucizumab for neovascular age-related macular degeneration. Ophthalmology. 2021;128(1):89–99 .
  • Sharma A, Kumar N, Kuppermann BD, et al. Brolucizimab-leading an era of structural revolution for long-term VEGF suppression. Eye. 2020;34(4):611–613.
  • Global shortage of eye drug Visudyne, not available again until early 2022. [cited 2021 Aug 12]. https://netherlandsnewslive.com/global-shortage-of-eye-drug-visudyne-not-available-again-until-early-2022/209401/.
  • Matsumoto H, Hoshino J, Mukai R, et al. Short-term outcomes of intravitreal brolucizumab for treatment-naïve neovascular age-related macular degeneration with type 1 choroidal neovascularization including polypoidal choroidal vasculopathy. Sci Rep. 2021;11(1):6759.
  • Fukuda Y, Sakurada Y, Matsubara M, et al. Comparison of outcomes between 3 monthly brolucizumab and aflibercept injections for polypoidal choroidal vasculopathy. Biomedicines. 2021;9(9):1164.6.
  • Ogura Y, Jaffe GJ, Cheung CMG, et al. Efficacy and safety of brolucizumab versus aflibercept in eyes with polypoidal choroidal vasculopathy in Japanese participants of HAWK. Br J Ophthalmol. 2021;106(7):994–999.
  • Ito A, Maruyama-Inoue M, Kitajima Y, et al. One-year outcomes of intravitreal brolucizumab injections in patients with polypoidal choroidal vasculopathy. Sci Rep. 2022;12(1):7987.
  • Chakraborty D, Maiti A, Sengupta S, et al. Initial experience in treating polypoidal choroidal vasculopathy with brolucizumab in Indian eyes - a multicenter retrospective study. Indian J Ophthalmol. 2022;70(4):1295–1299.
  • Koh A, Lai TYY, Takahashi K, et al. Efficacy and safety of ranibizumab with or without verteporfin photodynamic therapy for polypoidal choroidal vasculopathy: a randomized clinical trial. JAMA Ophthalmol. 2017;135(11):1206–1213.
  • Efficacy and safety of two different brolucizumab 6 mg dosing regimens in neovascular age-related macular degeneration (FALCON). [cited 2022 Jan 08]. https://clinicaltrials.gov/ct2/show/NCT04679935.

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