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Original Research

LncRNA HCG11 enhances the chemosensitivity of non-small cell lung cancer cells to Gemcitabine via miR-17-5p/p21 axis

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Pages 81-93 | Received 25 Jul 2023, Accepted 28 Dec 2023, Published online: 23 Jan 2024

References

  • Molina JR, Yang P, Cassivi SD, et al. Non-small cell lung cancer: epidemiology, risk factors, treatment, and survivorship. Mayo Clin Proc. 2008 May;83(5):584–94. PubMed PMID: 18452692; PubMed Central PMCID: PMCPMC2718421. doi: 10.1016/S0025-6196(11)60735-0
  • Hirsch FR, Scagliotti GV, Mulshine JL, et al. Lung cancer: current therapies and new targeted treatments. Lancet. 2017 Jan 21;389(10066):299–311. PubMed PMID: 27574741. doi: 10.1016/S0140-6736(16)30958-8
  • Sacco JJ, Al-Akhrass H, Wilson CM. Challenges and strategies in precision medicine for non-small-cell lung cancer. Curr Pharm Des. 2016;22(28):4374–85. PubMed PMID: 27262325. doi: 10.2174/1381612822666160603014932
  • Fatica A, Bozzoni I. Long non-coding RNAs: new players in cell differentiation and development. Nat Rev Genet. 2014 Jan;15(1):7–21. PubMed PMID: 24296535. doi: 10.1038/nrg3606
  • Sun W, Zu Y, Fu X, et al. Knockdown of lncRNA-XIST enhances the chemosensitivity of NSCLC cells via suppression of autophagy. Oncol Rep. 2017 Dec;38(6):3347–3354. PubMed PMID: 29130102; PubMed Central PMCID: PMCPMC5783579. doi: 10.3892/or.2017.6056
  • Liu Y, Jiang H, Zhou H, et al. Lentivirus-mediated silencing of HOTAIR lncRNA restores gefitinib sensitivity by activating Bax/Caspase-3 and suppressing TGF-alpha/EGFR signaling in lung adenocarcinoma. Oncol Lett. 2018 Mar;15(3):2829–2838. PubMed PMID: 29467862; PubMed Central PMCID: PMCPMC5778865. doi: 10.3892/ol.2017.7656
  • Yang T, Li H, Chen T, et al. LncRNA MALAT1 depressed chemo-sensitivity of NSCLC cells through directly functioning on miR-197-3p/p120 catenin axis. Mol Cells. 2019 Mar 31;42(3):270–283. PubMed PMID: 30841025; PubMed Central PMCID: PMCPMC6449715. doi: 10.14348/molcells.2019.2364
  • He J, Zhu S, Liang X, et al. LncRNA as a multifunctional regulator in cancer multi-drug resistance. Mol Biol Rep. 2021 Aug;48(8):1–15. PubMed PMID: 34333735. doi: 10.1007/s11033-021-06603-7
  • Li Y, Wang L, Xu X, et al. LncRNA HLA complex group 11 knockdown alleviates cisplatin resistance in gastric cancer by targeting the miR-144-3p/UBE2D1 axis. Cancer Manag Res. 2021;13:7543–7557. PubMed PMID: 34629901; PubMed Central PMCID: PMCPMC8493275. doi: 10.2147/CMAR.S329846
  • Zhang Y, Zhang P, Wan X, et al. Downregulation of long non-coding RNA HCG11 predicts a poor prognosis in prostate cancer. Biomed Pharmacother. 2016 Oct;83:936–941. PubMed PMID: 27522256. doi: 10.1016/j.biopha.2016.08.013
  • Bernhardt EB, Jalal SI. Small cell lung cancer. Cancer Treat Res. 2016;170:301–322. PubMed PMID: 27535400. doi: 10.1007/978-3-319-40389-2_14
  • Foy V, Schenk MW, Baker K, et al. Targeting DNA damage in SCLC. Lung Cancer. 2017 Dec;114:12–22. PubMed PMID: 29173760. doi: 10.1016/j.lungcan.2017.10.006
  • Xu Y, Zheng Y, Liu H, et al. Modulation of IGF2BP1 by long non-coding RNA HCG11 suppresses apoptosis of hepatocellular carcinoma cells via MAPK signaling transduction. Int J Oncol. 2017 Sep;51(3):791–800. PubMed PMID: 28677801; PubMed Central PMCID: PMCPMC5564403. doi: 10.3892/ijo.2017.4066
  • Chen Y, Bao C, Zhang X, et al. Long non-coding RNA HCG11 modulates glioma progression through cooperating with miR-496/CPEB3 axis. Cell Prolif. 2019 Sep;52(5):e12615. PubMed PMID: 31310044; PubMed Central PMCID: PMCPMC6797506. doi: 10.1111/cpr.12615
  • Zhang H, Huang H, Xu X, et al. LncRNA HCG11 promotes proliferation and migration in gastric cancer via targeting miR-1276/CTNNB1 and activating wnt signaling pathway. Cancer Cell Int. 2019;19:350. PubMed PMID: 31889902; PubMed Central PMCID: PMCPMC6933929. doi: 10.1186/s12935-019-1046-0
  • Wang G, Liu L, Zhang J, et al. LncRNA HCG11 suppresses cell proliferation and promotes apoptosis via sponging miR-224-3p in non-small-cell lung cancer cells. Onco Targets Ther. 2020;13:6553–6563. PubMed PMID: 32694917; PubMed Central PMCID: PMCPMC7340369. doi: 10.2147/OTT.S244181
  • Kulkarni B, Kirave P, Gondaliya P, et al. Exosomal miRNA in chemoresistance, immune evasion, metastasis and progression of cancer. Drug Discov Today. 2019 Oct;24(10):2058–2067. PubMed PMID: 31228614. doi: 10.1016/j.drudis.2019.06.010
  • Wang M, Gu H, Wang S, et al. Circulating miR-17-5p and miR-20a: molecular markers for gastric cancer. Mol Med Rep. 2012 Jun;5(6):1514–20. PubMed PMID: 22406928. doi: 10.3892/mmr.2012.828
  • Chatterjee A, Chattopadhyay D, Chakrabarti G, et al. miR-17-5p downregulation contributes to paclitaxel resistance of lung cancer cells through altering beclin1 expression. PloS One. 2014;9(4):e95716. PubMed PMID: 24755562; PubMed Central PMCID: PMCPMC3995800. doi: 10.1371/journal.pone.0095716
  • Jia J, Zhan D, Li J, et al. The contrary functions of lncRNA HOTAIR/miR-17-5p/PTEN axis and shenqifuzheng injection on chemosensitivity of gastric cancer cells. J Cell Mol Med. 2019 Jan;23(1):656–669. PubMed PMID: 30338929; PubMed Central PMCID: PMCPMC6307763. doi: 10.1111/jcmm.13970
  • Yan HJ, Liu WS, Sun WH, et al. miR-17-5p inhibitor enhances chemosensitivity to gemcitabine via upregulating bim expression in pancreatic cancer cells. Dig Dis Sci. 2012 Dec;57(12):3160–7. PubMed PMID: 23001407. doi: 10.1007/s10620-012-2400-4
  • Li H, Zhou H, Luo J, et al. MicroRNA-17-5p inhibits proliferation and triggers apoptosis in non-small cell lung cancer by targeting transforming growth factor beta receptor 2. Exp Ther Med. 2017 Jun;13(6):2715–2722. PubMed PMID: 28588663; PubMed Central PMCID: PMCPMC5450772. doi: 10.3892/etm.2017.4347
  • Wang Z, Zhang Q, Sun Y, et al. Long non-coding RNA PVT1 regulates BAMBI to promote tumor progression in non-small cell lung cancer by sponging miR-17-5p. Onco Targets Ther. 2020;13:131–142. PubMed PMID: 32021261; PubMed Central PMCID: PMCPMC6954835. doi: 10.2147/OTT.S217335
  • Zhang W, Lin J, Wang P, et al. miR-17-5p down-regulation contributes to erlotinib resistance in non-small cell lung cancer cells. J Drug Target. 2017 Feb;25(2):125–131. PubMed PMID: 27633093. doi: 10.1080/1061186X.2016.1207647
  • Chen C, Lu Z, Yang J, et al. MiR-17-5p promotes cancer cell proliferation and tumorigenesis in nasopharyngeal carcinoma by targeting p21. Cancer Med. 2016 Dec;5(12):3489–3499. PubMed PMID: 27774777; PubMed Central PMCID: PMCPMC5224848. doi: 10.1002/cam4.863
  • Shen Y, Lu L, Xu J, et al. Bortezomib induces apoptosis of endometrial cancer cells through microRNA-17-5p by targeting p21. Cell Biol Int. 2013 Oct;37(10):1114–1121. PubMed PMID: 23716467. doi: 10.1002/cbin.10139
  • Wang Z, Ji F. Downregulation of microRNA-17-5p inhibits drug resistance of gastric cancer cells partially through targeting p21. Oncol Lett. 2018 Apr;15(4):4585–4591. PubMed PMID: 29541229; PubMed Central PMCID: PMCPMC5835921. doi: 10.3892/ol.2018.7822
  • Wu SY, Lin KC, Chiou JF, et al. MicroRNA-17-5p post-transcriptionally regulates p21 expression in irradiated betel quid chewing-related oral squamous cell carcinoma cells. Strahlenther Onkol. 2013 Aug;189(8):675–683. PubMed PMID: 23780339. doi: 10.1007/s00066-013-0347-9
  • Xu S, Huang H, Chen YN, et al. DNA damage responsive miR-33b-3p promoted lung cancer cells survival and cisplatin resistance by targeting p21(WAF1/CIP1). Cell Cycle. 2016 Nov;15(21):2920–2930. PubMed PMID: 27559850; PubMed Central PMCID: PMCPMC5105918. doi: 10.1080/15384101.2016.1224043
  • Brugarolas J, Moberg K, Boyd SD, et al. Inhibition of cyclin-dependent kinase 2 by p21 is necessary for retinoblastoma protein-mediated G1 arrest after gamma-irradiation. Proc Natl Acad Sci U S A. 1999 Feb 2;96(3):1002–1007. PubMed PMID: 9927683; PubMed Central PMCID: PMCPMC15340. doi: 10.1073/pnas.96.3.1002
  • Liu Z, Sun M, Lu K, et al. The long noncoding RNA HOTAIR contributes to cisplatin resistance of human lung adenocarcinoma cells via downregualtion of p21(WAF1/CIP1) expression. PloS One. 2013;8(10):e77293. PubMed PMID: 24155936; PubMed Central PMCID: PMCPMC3796503. doi: 10.1371/journal.pone.0077293

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