Complement cascade on severe traumatic brain injury patients at the chronic unconscious stage: implication for pathogenesis

References

• Wade DT, Johnston C. The permanent vegetative state: practical guidance on diagnosis and management. Bmj. 1999;319:841–844.
   PubMed Web of Science ®Google Scholar
• Bernat JL. Chronic disorders of consciousness. Lancet. 2006;367:1181–1192.
   PubMed Web of Science ®Google Scholar
• Gao W, Lu C, Kochanek PM, et al. Serum amyloid A is increased in children with abusive head trauma: a gel-based proteomic analysis. Pediatr Res. 2014;76:280–286.
   PubMed Web of Science ®Google Scholar
• Poovindran Anada R, Wong KT, Jayapalan JJ, et al. Panel of serum protein biomarkers to grade the severity of traumatic brain injury. Electrophoresis. 2018 Mar 23. doi: 10.1002/elps.201700407. [Epub ahead of print].
   PubMedGoogle Scholar
• Lizhnyak PN, Ottens AK. Proteomics: in pursuit of effective traumatic brain injury therapeutics. Expert Rev Proteomics. 2015;12:75–82.
   PubMed Web of Science ®Google Scholar
• Zhang P, Zhu S, Li Y, et al. Quantitative proteomics analysis to identify diffuse axonal injury biomarkers in rats using iTRAQ coupled LC-MS/MS. J Proteomics. 2016;133:93–99.
   PubMed Web of Science ®Google Scholar
• Omenn GS. Plasma proteomics, the human proteome project, and cancer-associated alternative splice variant proteins. Biochim Biophys Acta. 2014;1844:866–873.
   PubMed Web of Science ®Google Scholar
• Mushkudiani NA, Hukkelhoven CW, Hernandez AV, et al. A systematic review finds methodological improvements necessary for prognostic models in determining traumatic brain injury outcomes. J Clin Epidemiol. 2008;61:331–343.
   PubMed Web of Science ®Google Scholar
• Babikian T, Alger JR, Ellis-Blied MU, et al. Whole brain magnetic resonance spectroscopic determinants of functional outcomes in pediatric moderate/severe traumatic brain injury. J Neurotrauma. 2018.
   PubMed Web of Science ®Google Scholar
• Ruet A, Joyeux F, Segobin S, et al. Severe TBI patients without focal lesion but with behavioral disorders: shrinkage of gray matter nuclei and thalamus revealed in a pilot voxel based MRI study. J Neurotrauma. 2018.
   PubMed Web of Science ®Google Scholar
• Bodien YG, Giacino JT, Edlow BL. Functional MRI motor imagery tasks to detect command following in traumatic disorders of consciousness. Front Neurol. 2017;8:688.
   PubMed Web of Science ®Google Scholar
• Woodcock T, Morganti-Kossmann MC. The role of markers of inflammation in traumatic brain injury. Front Neurol. 2013;4:18.
   PubMed Web of Science ®Google Scholar
• Giacino JT, Kalmar K, Whyte J. The JFK coma recovery scale-revised: measurement characteristics and diagnostic utility. Arch Phys Med Rehabil. 2004;85:2020–2029.
   PubMed Web of Science ®Google Scholar
• H J. Blood processing. ISBT Sci Ser. 2008;3:148–176.
   Google Scholar
• Pathan M, Keerthikumar S, Ang CS, et al. FunRich: an open access standalone functional enrichment and interaction network analysis tool. Proteomics. 2015;15:2597–2601.
   PubMed Web of Science ®Google Scholar
• Thelin EP, Just D, Frostell A, et al. Protein profiling in serum after traumatic brain injury in rats reveals potential injury markers. Behav Brain Res. 2018 Mar 15;340:71-80. doi: 10.1016/j.bbr.2016.08.058. Epub 2016 Aug 31.
   Web of Science ®Google Scholar
• Ricklin D, Hajishengallis G, Yang K, et al. Complement: a key system for immune surveillance and homeostasis. Nat Immunol. 2010;11:785–797.
   PubMed Web of Science ®Google Scholar
• Harboe M, Ulvund G, Vien L, et al. The quantitative role of alternative pathway amplification in classical pathway induced terminal complement activation. Clin Exp Immunol. 2004;138:439–446.
   PubMed Web of Science ®Google Scholar
• Brennan FH, Lee JD, Ruitenberg MJ, et al. Therapeutic targeting of complement to modify disease course and improve outcomes in neurological conditions. Semin Immunol. 2016;28:292–308.
   PubMed Web of Science ®Google Scholar
• Longhi L, Orsini F, De Blasio D, et al. Mannose-binding lectin is expressed after clinical and experimental traumatic brain injury and its deletion is protective. Crit Care Med. 2014;42:1910–1918.
   PubMed Web of Science ®Google Scholar
• Thelin EP, Just D, Frostell A, et al. Protein profiling in serum after traumatic brain injury in rats reveals potential injury markers. Behav Brain Res. 2018;340:71–80.
   PubMed Web of Science ®Google Scholar
• Fluiter K, Opperhuizen AL, Morgan BP, et al. Inhibition of the membrane attack complex of the complement system reduces secondary neuroaxonal loss and promotes neurologic recovery after traumatic brain injury in mice. J Immunol. 2014;192:2339–2348.
   PubMed Web of Science ®Google Scholar
• Brennan FH, Anderson AJ, Taylor SM, et al. Complement activation in the injured central nervous system: another dual-edged sword? J Neuroinflammation. 2012;9:137.
   PubMed Web of Science ®Google Scholar
• Shlosberg D, Benifla M, Kaufer D, et al. Blood-brain barrier breakdown as a therapeutic target in traumatic brain injury. Nat Rev Neurol. 2010;6:393–403.
   PubMed Web of Science ®Google Scholar
• Das M, Mohapatra S, Mohapatra SS. New perspectives on central and peripheral immune responses to acute traumatic brain injury. J Neuroinflammation. 2012;9:236.
   PubMed Web of Science ®Google Scholar
• Sahuquillo J, Poca MA, Amoros S. Current aspects of pathophysiology and cell dysfunction after severe head injury. Curr Pharm Des. 2001;7:1475–1503.
   PubMed Web of Science ®Google Scholar
• Osthoff M, Walder B, Delhumeau C, et al. Association of lectin pathway protein levels and genetic variants early after injury with outcomes after severe Traumatic brain injury: a prospective cohort study. J Neurotrauma. 2017;34:2560–2566.
   PubMed Web of Science ®Google Scholar
• Bramlett HM, Dietrich WD. Pathophysiology of cerebral ischemia and brain trauma: similarities and differences. J Cereb Blood Flow Metab. 2004;24:133–150.
   PubMed Web of Science ®Google Scholar
• Nguyen HX, Galvan MD, Anderson AJ. Characterization of early and terminal complement proteins associated with polymorphonuclear leukocytes in vitro and in vivo after spinal cord injury. J Neuroinflammation. 2008;5:26.
   PubMed Web of Science ®Google Scholar
• Bellander BM, Olafsson IH, Ghatan PH, et al. Secondary insults following traumatic brain injury enhance complement activation in the human brain and release of the tissue damage marker S100B. Acta Neurochir (Wien). 2011;153:90–100.
   PubMed Web of Science ®Google Scholar
• Hammad A, Westacott L, Zaben M. The role of the complement system in traumatic brain injury: a review. J Neuroinflammation. 2018;15:24.
   PubMed Web of Science ®Google Scholar