2,072
Views
1
CrossRef citations to date
0
Altmetric
Original Research

Villin expression in human tumors: a tissue microarray study on 14,398 tumors

, , , , , , , , , , , , , , , , , , , , , , , & show all
Pages 665-675 | Received 09 Nov 2021, Accepted 18 Jul 2022, Published online: 01 Aug 2022

References

  • Nakamura E, Iwakawa M, Furuta R, et al. Villin1, a novel diagnostic marker for cervical adenocarcinoma. Cancer Biol Ther. 2009;8(12):1146–1153.
  • George SP, Wang Y, Mathew S, et al. Dimerization and actin-bundling properties of villin and its role in the assembly of epithelial cell brush borders. J Biol Chem. 2007;282(36):26528–26541.
  • Bretscher A, Weber K. Villin is a major protein of the microvillus cytoskeleton which binds both G and F actin in a calcium-dependent manner. Cell. 1980;20(3):839–847.
  • Delacour D, Salomon J, Robine S, et al. Plasticity of the brush border - the yin and yang of intestinal homeostasis. Nat Rev Gastroenterol Hepatol. 2016;13(3):161–174.
  • Grone HJ, Weber K, Helmchen U, et al. Villin–a marker of brush border differentiation and cellular origin in human renal cell carcinoma. Am J Pathol. 1986;124(2):294–302.
  • Wang Y, George SP, Roy S, et al. Both the anti- and pro-apoptotic functions of villin regulate cell turnover and intestinal homeostasis. Sci Rep. 2016;6:35491.
  • Robine S, Huet C, Moll R, et al. Can villin be used to identify malignant and undifferentiated normal digestive epithelial cells? Proc Natl Acad Sci U S A. 1985;82(24):8488–8492.
  • Merchant SH, Amin MB, Tamboli P, et al. Primary signet-ring cell carcinoma of lung: immunohistochemical study and comparison with non-pulmonary signet-ring cell carcinomas. Am J Surg Pathol. 2001;25(12):1515–1519.
  • Moll R, Robine S, Dudouet B, et al. Villin: a cytoskeletal protein and a differentiation marker expressed in some human adenocarcinomas. Virchows Arch B Cell Pathol Incl Mol Pathol. 1987;54(3):155–169.
  • Droz D, Zachar D, Charbit L, et al. Expression of the human nephron differentiation molecules in renal cell carcinomas. Am J Pathol. 1990;137(4):895–905.
  • Lin F, Shi J, Zhu S, et al. Cadherin-17 and SATB2 are sensitive and specific immunomarkers for medullary carcinoma of the large intestine. Arch Pathol Lab Med. 2014;138(8):1015–1026.
  • Al-Maghrabi J, Gomaa W, Buhmeida A, et al. Loss of villin immunoexpression in colorectal carcinoma is associated with poor differentiation and survival. ISRN Gastroenterol. 2013;2013:679724.
  • Zhang MQ, Lin F, Hui P, et al. Expression of mucins, SIMA, villin, and CDX2 in small-intestinal adenocarcinoma. Am J Clin Pathol. 2007;128(5):808–816.
  • Mizoshita T, Tsukamoto T, Inada KI, et al. Loss of MUC2 expression correlates with progression along the adenoma-carcinoma sequence pathway as well as de novo carcinogenesis in the colon. Histol Histopathol. 2007;22(3):251–260.
  • Suh N, Yang XJ, Tretiakova MS, et al. Value of CDX2, villin, and alpha-methylacyl coenzyme A racemase immunostains in the distinction between primary adenocarcinoma of the bladder and secondary colorectal adenocarcinoma. Mod Pathol. 2005;18(9):1217–1222.
  • Nishizuka S, Chen S-T, Gwadry FG, et al. Diagnostic markers that distinguish colon and ovarian adenocarcinomas: identification by genomic, proteomic, and tissue array profiling. Cancer Res. 2003;63(17):5243–5250.
  • Cao HH, Zhang S-Y, Shen J-H, et al. A three-protein signature and clinical outcome in esophageal squamous cell carcinoma. Oncotarget. 2015;6(7):5435–5448.
  • Peng ZM, Yu W, Xie Y, et al. A four actin-binding protein signature model for poor prognosis of patients with esophageal squamous cell carcinoma. Int J Clin Exp Pathol. 2014;7(9):5950–5959.
  • Weimann A, Rieger A, Zimmermann M, et al. Comparison of six immunohistochemical markers for the histologic diagnosis of neoplasia in Barrett’s esophagus. Virchows Arch. 2010;457(5):537–545.
  • Pereira TC, Share SM, and Magalhães AV, et al. Can we tell the site of origin of metastatic squamous cell carcinoma? An immunohistochemical tissue microarray study of 194 cases. Appl Immunohistochem Mol Morphol. 2011;19(1):10–14.
  • Anders M, Sarbia M, Grotzinger C, et al. Expression of EpCam and villin in Barrett’s esophagus and in gastric cardia. Dis Markers. 2008;24(6):287–292.
  • Regalado SP, Nambu Y, and Iannettoni MD, et al. Abundant expression of the intestinal protein villin in Barrett’s metaplasia and esophageal adenocarcinomas. Mol Carcinog. 1998;22(3):182–189.
  • Seipel AH, Samaratunga H, Delahunt B, et al. Immunohistochemistry of ductal adenocarcinoma of the prostate and adenocarcinomas of non-prostatic origin: a comparative study. APMIS. 2016;124(4):263–270.
  • Gushima R, Yao T, Kurisaki-Arakawa A, et al. Expression of adipophilin in gastric epithelial neoplasia is associated with intestinal differentiation and discriminates between adenoma and adenocarcinoma. Virchows Arch. 2016;468(2):169–177.
  • Ran X, Xu X, and Yang Y, et al. A quantitative proteomics study on olfactomedin 4 in the development of gastric cancer. Int J Oncol. 2015;47(5):1932–1944.
  • Tian MM, Zhao AL, and Li ZW, et al. Phenotypic classification of gastric signet ring cell carcinoma and its relationship with clinicopathologic parameters and prognosis. World J Gastroenterol. 2007;13(23):3189–3198.
  • Yang Z. The utility of villin and mammaglobin in the differential diagnosis between intrahepatic cholangiocarcinoma and breast cancer. Appl Immunohistochem Mol Morphol. 2015;23(1):19–25.
  • Al-Muhannadi N, Ansari N, Brahmi U, et al. Differential diagnosis of malignant epithelial tumours in the liver: an immunohistochemical study on liver biopsy material. Ann Hepatol. 2011;10(4):508–515.
  • Lau SK, Prakash S, and Geller SA, et al. Comparative immunohistochemical profile of hepatocellular carcinoma, cholangiocarcinoma, and metastatic adenocarcinoma. Hum Pathol. 2002;33(12):1175–1181.
  • Nogales FF, Prat J, Schuldt M, et al. Germ cell tumour growth patterns originating from clear cell carcinomas of the ovary and endometrium: a comparative immunohistochemical study favouring their origin from somatic stem cells. Histopathol. 2018;72(4):634–647.
  • Roy S, Smith MA, Cieply KM, et al. Primary bladder adenocarcinoma versus metastatic colorectal adenocarcinoma: a persisting diagnostic challenge. Diagn Pathol. 2012;7:151.
  • Bian T, Zhao J, Feng J, et al. Combination of cadherin-17 and SATB homeobox 2 serves as potential optimal makers for the differential diagnosis of pulmonary enteric adenocarcinoma and metastatic colorectal adenocarcinoma. Oncotarget. 2017;8(38):63442–63452.
  • Calio A, Lever V, Rossi A, et al. Increased frequency of bronchiolar histotypes in lung carcinomas associated with idiopathic pulmonary fibrosis. Histopathol. 2017;71(5):725–735.
  • Wang CX, Liu B, Wang Y-F, et al. Pulmonary enteric adenocarcinoma: a study of the clinicopathologic and molecular status of nine cases. Int J Clin Exp Pathol. 2014;7(3):1266–1274.
  • Goldstein NS, Thomas M. Mucinous and nonmucinous bronchioloalveolar adenocarcinomas have distinct staining patterns with thyroid transcription factor and cytokeratin 20 antibodies. Am J Clin Pathol. 2001;116(3):319–325.
  • Nambu Y, Iannettoni MD, Orringer MB, et al. Unique expression patterns and alterations in the intestinal protein villin in primary and metastatic pulmonary adenocarcinomas. Mol Carcinog. 1998;23(4):234–242.
  • Tan J, Sidhu G, Greco MA, et al. Villin, cytokeratin 7, and cytokeratin 20 expression in pulmonary adenocarcinoma with ultrastructural evidence of microvilli with rootlets. Hum Pathol. 1998;29(4):390–396.
  • Nakamura E, Satoh T, Iwakawa M, et al. Villin1, a diagnostic marker for endometrial adenocarcinoma with high grade nuclear atypia. Cancer Biol Ther. 2011;12(3):181–190.
  • Dancau AM, Simon R, and Mirlacher M, et al. Tissue microarrays. Methods Mol Biol. 2016;1381:53–65.
  • Mirlacher M, Simon R. Recipient block TMA technique. Methods Mol Biol. 2010;664:37–44.
  • Kononen J, Bubendorf L, and Kallioniemie A, et al. Tissue microarrays for high-throughput molecular profiling of tumor specimens. Nat Med. 1998;4(7):844–847.
  • Uhlen M, Bandrowski A, Carr S, et al. A proposal for validation of antibodies. Nat Methods. 2016;13(10):823–827.
  • Uhlén M, Fagerbeg L, and Hallström BM , et al. Proteomics. Tissue-based map of the human proteome. Science. 2015;347(6220):1260419. DOI:10.1126/science.1260419.
  • Lizio M, Abugessaisa I, and Noguchi S , et al. Update of the FANTOM web resource: expansion to provide additional transcriptome atlases. Nucleic Acids Res. 2019;47(D1):D752–D758.
  • Lizio M, Harshbarger J, Shimoji H, et al. Gateways to the FANTOM5 promoter level mammalian expression atlas. Genome Biol. 2015;16:22.
  • Consortium GT. The Genotype-Tissue Expression (GTEx) project. Nat Genet. 2013;45(6):580–585.
  • Maunoury R, Robine S, Pringault E, et al. Villin expression in the visceral endoderm and in the gut anlage during early mouse embryogenesis. EMBO J. 1988;7(11):3321–3329.
  • Nogales FF, Quiñonez E, López-Marín L, et al. A diagnostic immunohistochemical panel for yolk sac (primitive endodermal) tumours based on an immunohistochemical comparison with the human yolk sac. Histopathol. 2014;65(1):51–59.
  • Nogales FF, Dulcey I. The secondary human yolk sac has an immunophenotype indicative of both hepatic and intestinal differentiation. Int J Dev Biol. 2012;56(9):755–760.
  • Sun L, Sakurai S, Sano T, et al. High-grade neuroendocrine carcinoma of the lung: comparative clinicopathological study of large cell neuroendocrine carcinoma and small cell lung carcinoma. Pathol Int. 2009;59(8):522–529.
  • Zhang PJ, Harris KR, and Alobeid B, et al. Immunoexpression of villin in neuroendocrine tumors and its diagnostic implications. Arch Pathol Lab Med. 1999;123(9):812–816.
  • Seidman JD, Yemelyanova A, and Zaino RJ, et al. The fallopian tube-peritoneal junction: a potential site of carcinogenesis. Int J Gynecol Pathol. 2011;30(1):4–11.
  • Arango D, Al-Obaidi S, and Williams DS, et al. Villin expression is frequently lost in poorly differentiated colon cancer. Am J Pathol. 2012;180(4):1509–1521.