Association between CDH1 methylation and esophageal cancer risk: a meta-analysis and bioinformatics study

References

• Sung H, Ferlay J, Siegel RL, et al., Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA Cancer J Clin. 2021;71(3): 209–249
   PubMed Web of Science ®Google Scholar
• Ferlay J, Ervik M, Lam F, et al. Global Cancer Observatory: cancer Today. Lyon, France: international Agency for Research on Cancer 2020. https://gco.iarc.fr/today [Accessed 2022 May 5
   Google Scholar
• Abnet CC, Arnold M, Wei WQ. Epidemiology of esophageal squamous cell carcinoma. Gastroenterology. 2018;154(2):360–373.
   PubMed Web of Science ®Google Scholar
• Melhado RE, Alderson D, Tucker O. The changing face of esophageal cancer. Cancers (Basel). 2010;2(3):1379–1404.
   PubMedGoogle Scholar
• Qin Y, Taylor W, Bamlet WR, et al. Methylated DNA markers of esophageal squamous cancer and dysplasia: an international study. Cancer Epidemiol Biomarkers Prev. 2020;29(12):2642–2650.
   PubMed Web of Science ®Google Scholar
• Siegel RL, Miller KD, Fuchs HE, et al. Cancer statistics. CA Cancer J Clin. 2022;72(1):7–33.
   PubMed Web of Science ®Google Scholar
• Gronnier C, Collet D. New Trends in Esophageal Cancer Management. Cancers (Basel). 2021;13(12):3030.
   PubMed Web of Science ®Google Scholar
• Chen R, Liu Y, Song G, et al. Effectiveness of one-time endoscopic screening programme in prevention of upper gastrointestinal cancer in China: a multicentre population- based cohort study. Gut. 2021;70(2):251–260.
   PubMed Web of Science ®Google Scholar
• Wang GQ, Jiao GG, Chang FB, et al., Long-term results of operation for 420 patients with early squamous cell esophageal carcinoma discovered by screening. Ann Thorac Surg. 2004;77(5): 1740–1744.
   PubMed Web of Science ®Google Scholar
• Katz-Summercorn AC, Jammula S, Frangou A, et al. Multi-omic cross-sectional cohort study of pre-malignant Barrett’s esophagus reveals early structural variation and retrotransposon activity. Nat Commun. 2022;13(1):1407.
   PubMed Web of Science ®Google Scholar
• Feng C, Dong J, Chang W, et al. The progress of methylation regulation in gene expression of cervical cancer. Int J Genomics. 2018;2018:8260652.
   PubMed Web of Science ®Google Scholar
• Talukdar FR, Soares Lima SC, Khoueiry R, et al. Genome-wide DNA methylation profiling of esophageal squamous cell carcinoma from global high-incidence regions identifies crucial genes and potential cancer markers. Cancer Res. 2021;81(10):2612–2624.
   PubMed Web of Science ®Google Scholar
• Ma K, Cao B, Guo M. The detective, prognostic, and predictive value of DNA methylation in human esophageal squamous cell carcinoma. Clin Epigenetics. 2016;8(1):43.
   PubMedGoogle Scholar
• Kim SA, Inamura K, Yamauchi M, et al. Loss of CDH1 (E-cadherin) expression is associated with infiltrative tumour growth and lymph node metastasis. Br J Cancer. 2016;114(2):199–206.
   PubMed Web of Science ®Google Scholar
• Wong SHM, Fang CM, Chuah LH, et al. E-cadherin: its dysregulation in carcinogenesis and clinical implications. Crit Rev Oncol Hematol. 2018;121:11–22.
   PubMed Web of Science ®Google Scholar
• Li W, Wu D, Niu Z, et al. 5-Azacytidine suppresses EC9706 cell proliferation and metastasis by upregulating the expression of SOX17 and CDH1. Int J Mol Med. 2016;38(4):1047–1054.
   PubMedGoogle Scholar
• Arimura N, Okada M, Taya S, et al. DSCAM regulates delamination of neurons in the developing midbrain. Sci Adv. 2020;6(36):1693.
   Web of Science ®Google Scholar
• Gupta S, Maitra A. EMT: matter of life or death? Cell. 2016;164(5):840–842.
   PubMed Web of Science ®Google Scholar
• Corn PG, Heath EI, Heitmiller R, et al. Frequent hypermethylation of the 5‘ CpG island of E-cadherin in esophageal adenocarcinoma. Clin Cancer Res. 2001;7(9):2765–2769.
   PubMed Web of Science ®Google Scholar
• Moher D, Liberati A, Tetzlaff J, et al. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. BMJ. 2009;339(jul21 1):b2535.
   PubMed Web of Science ®Google Scholar
• Nie Y, Liao J, Zhao X, et al. Detection of multiple gene hypermethylation in the development of esophageal squamous cell carcinoma. Carcinogenesis. 2002;23(10):1713–1720.
   PubMed Web of Science ®Google Scholar
• Brock MV, Gou M, Akiyama Y, et al. Prognostic importance of promoter hypermethylation of multiple genes in esophageal adenocarcinoma. Clin Cancer Res. 2003;9(8):2912–2919.
   PubMed Web of Science ®Google Scholar
• Schildhaus HU, Kröckel I, Lippert H, et al. Promoter hypermethylation of p16INK4a, E-cadherin, O6-MGMT, DAPK and FHIT in adenocarcinomas of the esophagus, esophagogastric junction and proximal stomach. Int J Oncol. 2005;26(6):1493–1500.
   PubMed Web of Science ®Google Scholar
• Guo M, Ren J, House MG, et al., Accumulation of promoter methylation suggests epigenetic progression in squamous cell carcinoma of the esophagus. Clin Cancer Res. 2006;12(15): 4515–4522.
   PubMed Web of Science ®Google Scholar
• Ikoma D, Ichikawa D, Ueda Y, et al. Circulating tumor cells and aberrant methylation as tumor markers in patients with esophageal cancer. Anticancer Res. 2007;27(1B):535–539.
   PubMed Web of Science ®Google Scholar
• Miao LS, Xiang JQ, Zhang YW, et al. Promoter methylation and its significance of hMLH1, E-cadherin and p16 INK4a gene in esophageal squamous cell carcinoma. China Oncology. 2009;19(5): 340–346
   Google Scholar
• Guo YL, Guo W, Yang ZB, et al. Promoter hypermethylation of CDH1 gene and ectopic expression of β-catenin in esophageal squamous cell cancer. Chinese Journal of Clinical Oncology. 2011;38(1): 5–9
   Google Scholar
• Li B, Wang B, Niu LJ, et al. Hypermethylation of multiple tumor-related genes associated with DNMT3b up-regulation served as a biomarker for early diagnosis of esophageal squamous cell carcinoma. Epigenetics. 2011;6(3):307–316.
   PubMed Web of Science ®Google Scholar
• Ling ZQ, Li P, Ge MH, et al. Hypermethylation-modulated down-regulation of CDH1 expression contributes to the progression of esophageal cancer. Int J Mol Med. 2011;27(5):625–635.
   PubMed Web of Science ®Google Scholar
• Wang CC, Mao WM, Ling ZQ. Methylation of tumor suppressor genes and clinical significance in esophageal squamous cell carcinoma. Chin J Gastroenter 2012; 17(1): 19–22
   Google Scholar
• Ganji S, Samei E, Rastgar-Jazii F, et al. E-cadherin Promoter Methylation Comparison and Correlation with the Pathological Features of the Squamous Cell Carcinoma of Esophagus in the High Risk Region. Journal of Sciences Islamic Republic of Iran. 2014;25(1): 19–26
   Google Scholar
• Guilleret I, Losi L, Chelbi ST, et al. DNA methylation profiling of esophageal adenocarcinoma using Methylation Ligation-dependent Macroarray (MLM). Biochem Biophys Res Commun. 2016;479(2):231–237.
   PubMed Web of Science ®Google Scholar
• Atakpo P, Vassar M. Publication bias in dermatology systematic reviews and meta-analyses. J Dermatol Sci. 2016;82(2):69–74.
   PubMed Web of Science ®Google Scholar
• Onishi A, Furukawa TA. Publication bias is underreported in systematic reviews published in high-impact-factor journals: metaepidemiologic study. J Clin Epidemiol. 2014;67(12):1320–1326.
   PubMed Web of Science ®Google Scholar
• Lin L, Chu H. Quantifying publication bias in meta-analysis. Biometrics. 2018;74(3):785–794.
   PubMed Web of Science ®Google Scholar
• Liu K, Zhao T, Wang J, et al. Etiology, cancer stem cells and potential diagnostic biomarkers for esophageal cancer. Cancer Lett. 2019;458:21–28.
   PubMed Web of Science ®Google Scholar
• Dong Z, Liang X, Wu X, et al. Promoter hypermethylation-mediated downregulation of tumor suppressor gene SEMA3B and lncRNA SEMA3B-AS1 correlates with progression and prognosis of esophageal squamous cell carcinoma. Clin Exp Metastasis. 2019;36(3):225–241.
   PubMed Web of Science ®Google Scholar
• Fan Z, Qin Y, Zhou J, et al. Feasibility of using P16 methylation as a cytologic marker for esophageal squamous cell carcinoma screening: a pilot study. Cancer Med. 2022. 10.1002/cam4.4718.
   Web of Science ®Google Scholar
• Moriichi K, Watari J, Das KM, et al. Effects of Helicobacter pylori infection on genetic instability, the aberrant CpG island methylation status and the cellular phenotype in Barrett’s esophagus in a Japanese population. Int J Cancer. 2009;124(6):1263–1269.
   PubMed Web of Science ®Google Scholar
• Eads CA, Lord RV, Wickramasinghe K, et al. Epigenetic patterns in the progression of esophageal adenocarcinoma. Cancer Res. 2001;61(8):3410–3418.
   PubMed Web of Science ®Google Scholar
• Hlady RA, Tiedemann RL, Puszyk W, et al. Epigenetic signatures of alcohol abuse and hepatitis infection during human hepatocarcinogenesis. Oncotarget. 2014;5(19):9425–9443.
   PubMedGoogle Scholar
• Qin Y, Wu CW, Taylor WR, et al., Discovery, validation, and application of novel methylated DNA markers for detection of esophageal cancer in plasma. Clin Cancer Res. 2019;25(24): 7396–7404.
   PubMed Web of Science ®Google Scholar
• Dvorská D, Braný D, Nagy B, et al. aberrant methylation status of tumour suppressor genes in ovarian cancer tissue and paired plasma samples. Int J Mol Sci. 2019;20(17):4119.
   Web of Science ®Google Scholar
• Zeng W, Zhu J, Shan L, et al. The clinicopathological significance of CDH1 in gastric cancer: a meta-analysis and systematic review. Drug Des Devel Ther. 2015;9:2149–2157.
   PubMed Web of Science ®Google Scholar
• Zhao XJ, Li H, Chen H, et al. Expression of e-cadherin and beta-catenin in human esophageal squamous cell carcinoma: relationships with prognosis. World J Gastroenterol. 2003;9(2):225–232.
   PubMed Web of Science ®Google Scholar
• Lin Y, Shen LY, Fu H, et al. P21, COX-2, and E-cadherin are potential prognostic factors for esophageal squamous cell carcinoma. Dis Esophagus. 2017;30(2):1–10.
   Web of Science ®Google Scholar
• Ishiguro H, Wakasugi T, Terashita Y, et al. Decreased expression of CDH1 or CTNNB1 affects poor prognosis of patients with esophageal cancer. World J Surg Oncol. 2016;14(1):240.
   PubMedGoogle Scholar
• Xu XL, Ling ZQ, Chen SZ, et al. The impact of E-cadherin expression on the prognosis of esophageal cancer: a meta-analysis. Dis Esophagus. 2014;27(1):79–86.
   PubMed Web of Science ®Google Scholar