195
Views
7
CrossRef citations to date
0
Altmetric
Original Research

Cost-effectiveness of Intrathecal Baclofen Therapy in severe refractory non-focal disabling spasticity: a Spanish hospital perspective

, , , , &
Pages 67-76 | Received 15 Feb 2016, Accepted 15 Apr 2016, Published online: 03 May 2016

References

  • Nair KPS, Marsden J. The management of spasticity in adults. BMJ. 2014;349:g4737.
  • Sampson FC, Hayward A, Evans G, et al. Functional benefits and cost/benefit analysis of continuous intrathecal baclofen infusion for the management of severe spasticity. J Neurosurg. 2002;96:1052–1057.
  • Vivancos-matellano F, Pascual-pascual SI, Nardi-vilardaga J, et al. [Guide to the comprehensive treatment of spasticity]. Rev Neurol. 2007;45:365–375.
  • Bavikatte G, Gaber T. Approach to spasticity in general practice. Br J Med Pract. 2009;2:29–34.
  • Ward AB. A summary of spasticity management–a treatment algorithm. Eur J Neurol. 2002;9:48–52.
  • Hsieh JC, Penn RD. Intrathecal baclofen in the treatment of adult spasticity. Neurosurg Focus. 2006;21:e5.
  • McIntyre A, Mays R, Mehta S, et al. Examining the effectiveness of intrathecal baclofen on spasticity in individuals with chronic spinal cord injury: a systematic review. J Spinal Cord Med. 2014;37:11–18.
  • Medical Advisory Secretariat. Intrathecal baclofen pump for spasticity: an evidence-based analysis. Ont Health Technol Assess Ser. 2005;5:1–93.
  • Vidal J, Fenollosa P, Martin E, et al. Safety and efficacy of intrathecal baclofen infusion by implantable pump for the treatment of severe spinal spasticity: a Spanish multicenter study. Neuromodulation. 2000;3:175–182.
  • Motta F, Antonello CE. Analysis of complications in 430 consecutive pediatric patients treated with intrathecal baclofen therapy: 14-year experience. J Neurosurg Pediatr. 2014;13:301–306.
  • Zahavi A, Geertzen JHB, Middel B, et al. Long term effect (more than five years) of intrathecal baclofen on impairment, disability, and quality of life in patients with severe spasticity of spinal origin. J Neurol Neurosurg Psychiatry. 2004;75:1553–1557.
  • Saulino M, Guillemette S, Leier J, et al. Medical cost impact of intrathecal baclofen therapy for severe spasticity. Neuromodulation. 2015;18:141–149.
  • Hoving MA, Evers SMAA, Ament AJHA, et al. Intrathecal baclofen therapy in children with intractable spastic cerebral palsy: a cost-effectiveness analysis. Dev Med Child Neurol. 2008;50:450–455.
  • de Lissovoy G, Matza LS, Green H, et al. Cost-effectiveness of intrathecal baclofen therapy for the treatment of severe spasticity associated with cerebral palsy. J Child Neurol. 2007;22:49–59.
  • Bensmail D, Ward AB, Wissel J, et al. Cost-effectiveness modeling of intrathecal baclofen therapy versus other interventions for disabling spasticity. Neurorehabil Neural Repair. 2009;23:546–552.
  • Hattori N, Hirayama T, Katayama Y. Cost-effectiveness analysis of intrathecal baclofen therapy in Japan. Neurol Med Chir (Tokyo). 2012;52:482–487.
  • Mathur SN, Chu SK, McCormick Z, et al. Long-term intrathecal baclofen: outcomes after more than 10 years of treatment. PM R. 2014;6:506–513.e1.
  • Natale M, Mirone G, Rotondo M, et al. Intrathecal baclofen therapy for severe spasticity: analysis on a series of 112 consecutive patients and future prospectives. Clin Neurol Neurosurg. 2012;114:321–325.
  • Draulans N, Vermeersch K, Degraeuwe B, et al. Intrathecal baclofen in multiple sclerosis and spinal cord injury: complications and long-term dosage evolution. Clin Rehabil. 2013;27:1137–1143.
  • Borrini L, Bensmail D, Thiebaut JB, et al. Occurrence of adverse events in long-term intrathecal baclofen infusion: a 1-year follow-up study of 158 adults. Arch Phys Med Rehabil. 2014;95:1032–1038.
  • Heetla HW, Staal MJ, Kliphuis C, et al. The incidence and management of tolerance in intrathecal baclofen therapy. Spinal Cord. 2009;47:751–756.
  • Flückiger B, Knecht H, Grossmann S, et al. Device-related complications of long-term intrathecal drug therapy via implanted pumps. Spinal Cord. 2008;46:639–643.
  • Vidal J, Gregori P, Guevara D, et al. Efficacy of intrathecal morphine in the treatment of baclofen tolerance in a patient on intrathecal baclofen therapy (ITB). Spinal Cord. 2004;42:50–51.
  • Ordia JI, Fischer E, Adamski E, et al. Continuous intrathecal baclofen infusion by a programmable pump in 131 consecutive patients with severe spasticity of spinal origin. Neuromodulation. 2002;5:16–24.
  • Spanish National Statistics Institute. INEbase [ cited 2015 Mar 15]. Available from: http://www.ine.es
  • López Bastida J, Oliva J, Antoñanzas F, et al. A proposed guideline for economic evaluation of health technologies. Gac Sanit. 2010;24:154–170.
  • Delhaas EM, Beersen N, Redekop WK, et al. Long-term outcomes of continuous intrathecal baclofen infusion for treatment of spasticity: a prospective multicenter follow-up study. Neuromodulation. 2008;11:227–236.
  • Medtronic Inc. Medtronic product performance report 2014 [ cited 2015 Nov 20]. Available from: http://professional.medtronic.com/ppr/intrathecal-drug-delivery-systems/index.htm
  • Saval A, Chiodo AE. Intrathecal baclofen for spasticity management: a comparative analysis of spasticity of spinal vs cortical origin. J Spinal Cord Med. 2010;33:16–21.
  • De Cock E, Miravitlles M, González-Juanatey JR, et al. Valor umbral del coste por año de vida ganado para recomendar la adopción de tecnologías sanitarias en España: evidencias procedentes de una revisión de la literatura. PharmacoEconomics Spanish Res Artic. 2007;4:97–107.
  • Rodriguez JM, Paz S, Lizan L, et al. The use of quality-adjusted life-years in the economic evaluation of health technologies in Spain: a review of the 1990–2009 literature. Value Health. 2011;14:458–464.
  • Sacristán JA, Oliva J, Del Llano J, et al. [What is an efficient health technology in Spain?]. Gac Sanit. 2002;16:334–343.
  • Guillaume D, Van Havenbergh A, Vloeberghs M, et al. A clinical study of intrathecal baclofen using a programmable pump for intractable spasticity. Arch Phys Med Rehabil. 2005;86:2165–2171.
  • Staal C, Arends A, Ho S. A self-report of quality of life of patients receiving intrathecal baclofen therapy. Rehabil Nurs. 2003;28:159–163.
  • Vender JR, Hughes M, Hughes BD, et al. Intrathecal baclofen therapy and multiple sclerosis: outcomes and patient satisfaction. Neurosurg Focus. 2006;21:e6.
  • Gunnarsson S, Samuelsson K. Patient experiences with intrathecal baclofen as a treatment for spasticity – a pilot study. Disabi Rehabil. 2015;37:834–841.
  • Sadiq SA, Wang GC. Long-term intrathecal baclofen therapy in ambulatory patients with spasticity. J Neurol. 2006;253:563–569.
  • Dones I, Marchetti M, Sinisi M, et al. Cautious use of intrathecal baclofen in severely spastic walking patients. Mov Disord. 2002;17:S337–S337.
  • Schiess MC, Oh IJ, Stimming EF, et al. Prospective 12-month study of intrathecal baclofen therapy for poststroke spastic upper and lower extremity motor control and functional improvement. Neuromodulation. 2011;14:38–45.
  • Arroyo R, Vila C, Clissold S. Retrospective observational study of the management of multiple sclerosis patients with resistant spasticity in Spain: the “5E” study. Expert Rev Pharmacoecon Outcomes Res. 2011;11:205–213.
  • Arroyo R, Massana M, Vila C. Correlation between spasticity and quality of life in patients with multiple sclerosis: the CANDLE study. Int J Neurosci. 2013;123:850–858.
  • Slof J, Gras A. Sativex® in multiple sclerosis spasticity: a cost–effectiveness model. Expert Rev Pharmacoecon Outcomes Res. 2012;12:439–441.
  • Svensson J, Borg S, Nilsson P. Costs and quality of life in multiple sclerosis patients with spasticity. Acta Neurol Scand. 2014;129:13–20.
  • Slof J, Serrano D, Álvarez López-Dóriga M, et al. Clinical outcomes and health care resource utilization in a 1-year observational study of patients with non-focal disabling spasticity who are resistant or intolerant to oral therapy treated with intrathecal baclofen therapy at the Institut Guttmann (Spain). Epice study. Value Health. 2014;17:A396.
  • General Council of Spanish Pharmacists. Official medicines catalog [ cited 2014 Feb 27]. Available from: https://botplusweb.portalfarma.com/

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.