Cost implications of adverse drug event-related emergency department visits – a multicenter study in South Korea

References

• Mello MM, Studdert DM, Thomas EJ, et al. Who pays for medical errors? An analysis of adverse event costs, the medical liability system, and incentives for patient safety improvement. J Empir Leg Stud. 2007;4(4):835–860.
   Google Scholar
• Becker ML, Kallewaard M, Caspers PW, et al. Hospitalisations and emergency department visits due to drug–drug interactions: a literature review. Pharmacoepidemiol Drug Saf. 2007;16(6):641–651.
   PubMed Web of Science ®Google Scholar
• Bayoumi I, Dolovich L, Hutchison B, et al. Medication-related emergency department visits and hospitalizations among older adults. Can Fam Physician. 2014;60(4):e217–e222.
   PubMed Web of Science ®Google Scholar
• Cohen AL, Jhung MA, Budnitz DS. Stimulant medications and attention deficit–hyperactivity disorder. N Engl J Med. 2006;354(21):2294–2295.
   PubMed Web of Science ®Google Scholar
• Budnitz DS, Lovegrove MC, Shehab N, et al. Emergency hospitalizations for adverse drug events in older Americans. N Engl J Med. 2011;365(21):2002–2012.
   PubMed Web of Science ®Google Scholar
• Schillie SF, Shehab N, Thomas KE, et al. Medication overdoses leading to emergency department visits among children. Am J Prev Med. 2009;37(3):181–187.
   PubMed Web of Science ®Google Scholar
• Shehab N, Patel PR, Srinivasan A, et al. Emergency department visits for antibiotic-associated adverse events. Clin Infect Dis. 2008;47(6):735–743.
   PubMed Web of Science ®Google Scholar
• Gertler SA, Coralic Z, López A, et al. Root cause analysis of ambulatory adverse drug events that present to the emergency department. J Patient Saf. 2016;12(3):119–124.
   PubMed Web of Science ®Google Scholar
• Chen Y-C, Fan J-S, Chen M-H, et al. Risk factors associated with adverse drug events among older adults in emergency department. Eur J Int Med. 2014;25(1):49–55.
   PubMed Web of Science ®Google Scholar
• Wasserfallen J-B, Livio F, Buclin T, et al. Rate, type, and cost of adverse drug reactions in emergency department admissions. Eur J Int Med. 2001;12(5):442–447.
   PubMedGoogle Scholar
• Queneau P, Bannwarth B, Carpentier F, et al. Emergency department visits caused by adverse drug events. Drug Saf. 2007;30(1):81–88.
   PubMed Web of Science ®Google Scholar
• Kessler ER, Shah M, Gruschkus SK, et al. Cost and quality implications of opioid‐based postsurgical pain control using administrative claims data from a large health system: opioid‐related adverse events and their impact on clinical and economic outcomes. Pharmacother. 2013;33(4):383–391.
   PubMed Web of Science ®Google Scholar
• Hassett MJ, O‘Malley AJ, Pakes JR, et al. Frequency and cost of chemotherapy-related serious adverse effects in a population sample of women with breast cancer. J Natl Cancer Inst. 2006;98(16):1108–1117.
   PubMedGoogle Scholar
• Lahue BJ, Pyenson B, Iwasaki K, et al. National burden of preventable adverse drug events associated with inpatient injectable medications: healthcare and medical professional liability costs. Am Health Drug Benefits. 2012;5(7):1.
   PubMedGoogle Scholar
• Borovicka JH, Calahan C, Gandhi M, et al. Economic burden of dermatologic adverse events induced by molecularly targeted cancer agents. Arch Dermat. 2011;147(12):1403–1409.
   PubMedGoogle Scholar
• Ruger JP, Richter CJ, Spitznagel EL, et al. Analysis of costs, length of stay, and utilization of emergency department services by frequent users: implications for health policy. Acad Emerg Med. 2004;11(12):1311–1317.
   PubMed Web of Science ®Google Scholar
• Solberg RG, Edwards BL, Chidester JP, et al. The prehospital and hospital costs of emergency care for frequent ED patients. Am J Emerg Med. 2016;34(3):459–463.
   PubMed Web of Science ®Google Scholar
• Wu C, Bell CM, Wodchis WP. Incidence and economic burden of adverse drug reactions among elderly patients in Ontario emergency departments. Drug Saf. 2012;35(9):769–781.
   PubMed Web of Science ®Google Scholar
• Ayani I, Aguirre C, Gutierrez G, et al. A cost‐analysis of suspected adverse drug reactions in a hospital emergency ward. Pharmacoepidemiol Drug Saf. 1999;8(7):529–534.
   PubMed Web of Science ®Google Scholar
• Pirmohamed M, James S, Meakin S, et al. Adverse drug reactions as cause of admission to hospital: prospective analysis of 18 820 patients. BMJ. 2004;329(7456):15–19.
   PubMed Web of Science ®Google Scholar
• Naranjo CA, Busto U, Sellers EM, et al. A method for estimating the probability of adverse drug reactions. Clin Pharmacol Ther. 1981;30(2):239–245.
   PubMed Web of Science ®Google Scholar
• Poudel DR, Acharya P, Ghimire S, et al. Burden of hospitalizations related to adverse drug events in the USA: a retrospective analysis from large inpatient database. Pharmacoepidemiol Drug Saf. 2017;26(6):635–641.
   PubMed Web of Science ®Google Scholar
• Schneeweiss S, Hasford J, Göttler M, et al. Admissions caused by adverse drug events to internal medicine and emergency departments in hospitals: a longitudinal population-based study. Eur J Clin Pharmacol. 2002;58(4):285–291.
   PubMed Web of Science ®Google Scholar
• Meier F, Maas R, Sonst A, et al. Adverse drug events in patients admitted to an emergency department: an analysis of direct costs. Pharmacoepidemiol Drug Saf. 2015;24(2):176–186.
   PubMed Web of Science ®Google Scholar
• Roh EJ, Won YK, Lee M-H, et al. Clinical characteristics of patients with acute bronchiolitis who visited 146 Emergency Department in Korea in 2012. Asthma Respir Dis. 2015;3(5):334–340.
   Web of Science ®Google Scholar
• Yang HJ, Kim GW, Kim H, et al. Epidemiology and outcomes in out-of-hospital cardiac arrest: a report from the NEDIS-based cardiac arrest registry in Korea. J Kor Med Sci. 2015;30(1):95–103.
   PubMed Web of Science ®Google Scholar
• Jung S, Lim H, Kwon J, et al. P077: the health inequalities among foreign patients visiting the emergency room with injury: a nationwide population-based study in South Korea, 2013-2015. Can J Emerg Med. 2018;20(S1):S84–S84.
   Google Scholar
• Parida S. Clinical causality assessment for adverse drug reactions. Ind J Anesthesia. 2013;57(3):325.
   PubMedGoogle Scholar
• Danan G, Teschke R. RUCAM in drug and herb induced liver injury: the update. Int J Mol Sci. 2015;17(1):14.
   PubMed Web of Science ®Google Scholar
• Suk KT, Kim DJ, Kim CH, et al. A prospective nationwide study of drug-induced liver injury in Korea. Am J Gastroenterol. 2012;107(9):1380.
   PubMed Web of Science ®Google Scholar
• Cho J-H, Oh D-S, Hong S-H, et al. A nationwide study of the incidence rate of herb-induced liver injury in Korea. Arch Toxicol. 2017;91(12):4009–4015.
   PubMed Web of Science ®Google Scholar
• Hartwig SC, Siegel J, Schneider PJ. Preventability and severity assessment in reporting adverse drug reactions. Am J Hosp Pharm. 1992;49(9):2229–2232.
   PubMedGoogle Scholar
• Schumock GT, Thornton JP. Focusing on the preventability of adverse drug reactions. Hosp Pharm. 1992;27(6):538.
   PubMedGoogle Scholar
• Blough DK, Ramsey SD. Using generalized linear models to assess medical care costs. Health Serv Outcomes Res Methodol. 2000;1(2):185–202.
   Google Scholar
• Chiatti C, Bustacchini S, Furneri G, et al. The economic burden of inappropriate drug prescribing, lack of adherence and compliance, adverse drug events in older people. Drug Saf. 2012;35(1):73–87.
   PubMedGoogle Scholar
• Dormann H, Neubert A, Criegee‐Rieck M, et al. Readmissions and adverse drug reactions in internal medicine: the economic impact. J Int Med. 2004;255(6):653–663.
   PubMed Web of Science ®Google Scholar
• Rottenkolber D, Schmiedl S, Rottenkolber M, et al. Adverse drug reactions in Germany: direct costs of internal medicine hospitalizations. Pharmacoepidemiol Drug Saf. 2011;20(6):626–634.
   PubMed Web of Science ®Google Scholar
• Myer PA, Mannalithara A, Singh G, et al. Clinical and economic burden of emergency department visits due to gastrointestinal diseases in the United States. Am J Gastroenterol. 2013;108(9):1496.
   PubMed Web of Science ®Google Scholar
• Patel K, Kedia M, Bajpai D, et al. Evaluation of the prevalence and economic burden of adverse drug reactions presenting to the medical emergency department of a tertiary referral centre: a prospective study. BMC Clin Pharmacol. 2007;7(1):8.
   PubMedGoogle Scholar
• Schurig AM, Böhme M, Just KS, et al. Adverse drug reactions (ADR) and emergencies: the prevalence of suspected ADR in four emergency departments in Germany. Dtsch Ärztebl Int. 2018;115(15):251.
   PubMed Web of Science ®Google Scholar
• Rottenkolber D, Hasford J, Stausberg J. Costs of adverse drug events in German hospitals – a microcosting study. Value Health. 2012;15(6):868–875.
   PubMed Web of Science ®Google Scholar
• Rydberg DM, Holm L, Engqvist I, et al. Adverse drug reactions in a tertiary care emergency medicine ward-prevalence, preventability and reporting. PloS One. 2016;11(9):e0162948.
   PubMed Web of Science ®Google Scholar
• Kim L, Kim J, Kim S. A guide for the utilization of health insurance review and assessment service national patient samples. Epidemiol Health. 2014;36:e2014008.
   PubMedGoogle Scholar
• Kanjanarat P, Winterstein AG, Johns TE, et al. Nature of preventable adverse drug events in hospitals: a literature review. Am J Health Syst Pharm. 2003;60(17):1750–1759.
   PubMed Web of Science ®Google Scholar
• Bates DW, Spell N, Cullen DJ, et al. The costs of adverse drug events in hospitalized patients. JAMA. 1997;277(4):307–311.
   PubMed Web of Science ®Google Scholar
• Belhekar MN, Taur SR, Munshi RP. A study of agreement between the Naranjo algorithm and WHO-UMC criteria for causality assessment of adverse drug reactions. Ind J Pharmacol. 2014;46(1):117-120.
   Google Scholar
• Zed PJ, Abu-Laban RB, Balen RM, et al. Incidence, severity and preventability of medication-related visits to the emergency department: a prospective study. Can Med Assoc J. 2008;178(12):1563–1569.
   PubMed Web of Science ®Google Scholar
• Yang M-S, Kim J-Y, Kang M-G, et al. Direct costs of severe cutaneous adverse reactions in a tertiary hospital in Korea. Kor J Int Med. 2019;34(1):195.
   PubMed Web of Science ®Google Scholar