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Original Research

Cost-effectiveness analysis of second-line pharmacological treatment of acromegaly in Spain

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Pages 105-114 | Received 05 Feb 2019, Accepted 18 Apr 2019, Published online: 06 May 2019

References

  • Lavrentaki A, Paluzzi A, Wass JA, et al. Epidemiology of acromegaly: review of population studies. Pituitary. 2017;20(1):4–9.
  • Mestron A, Webb SM, Astorga R, et al. Epidemiology, clinical characteristics, outcome, morbidity and mortality in acromegaly based on the Spanish Acromegaly Registry (Registro Espanol de Acromegalia, REA). Eur J Endocrinol. 2004;151(4):439–446.
  • Sesmilo G, Gaztambide S, Venegas E, et al. REA investigators. Changes in acromegaly treatment over four decades in Spain: analysis of the Spanish Acromegaly Registry (REA). Pituitary. 2013;16(1):115–121.
  • Cordido F, García Arnés JA, Marazuela Aspiroz M, et al. grupo de Neuroendocrinología de la Sociedad Española de Endocrinología y Nutrición. [Practical guidelines for diagnosis and treatment of acromegaly. Grupo de Neuroendocrinología de la Sociedad Española de Endocrinología y Nutrición]. Endocrinol Nutr. 2013;60(8):457.e1–457.e15.
  • Katznelson L, Laws ER Jr, Melmed S, et al. Endocrine society. Acromegaly: an endocrine society clinical practice guideline. J Clin Endocrinol Metab. 2014;99(11):3933–3951.
  • Sesmilo G, Webb SM. Neuroendocrinology group of the spanish society of endocrinology and nutrition. Twelve years of the Spanish acromegaly registry: a historical view of acromegaly management in Spain. Endocrinol Nutr. 2010;57(2):39–42.
  • EMA. Ficha Técnica Somavert (Pegvisomant). 2016. [Cited 2018 Jun]. [ Available from: http://www.ema.europa.eu/docs/es_ES/document_library/EPAR_-_Product_Information/human/000409/WC500054629.pdf
  • EMA. Ficha Técnica Signifor Pasireotida). 2016. [Cited 2018 Jun]. Available from: http://www.ema.europa.eu/docs/es_ES/document_library/EPAR_-_Product_Information/human/002052/WC500128056.pdf.
  • Melmed S, Bronstein MD, Chanson P, et al. A consensus statement on acromegaly therapeutic outcomes. Nat Rev Endocrinol. 2018;14(9):552–561.
  • Gadelha MR, Bronstein MD, Brue T, et al. Pasireotide C2402 study group. Pasireotide versus continued treatment with octreotide or lanreotide in patients with inadequately controlled acromegaly (PAOLA): a randomised, phase 3 trial. Lancet Diabetes Endocrinol. 2014;2(11):875–884. .
  • Trainer PJ, Drake WM, Katznelson L, et al. Treatment of acromegaly with the growth hormone-receptor antagonist pegvisomant. N Engl J Med. 2000;342(16):1171–1177.
  • López Bastida J, Oliva J, Antoñanzas F, et al. [A proposed guideline for economic evaluation of health technologies]. Gac Sanit. 2010;24(2):154–170.
  • INE. Defunciones por edad, mes y sexo. Datos provisionales Año 2015 2016. 2015. [Cited 2018 Jun]. Available from: http://www.ine.es.
  • Holdaway IM, Bolland MJ, Gamble GD. A meta-analysis of the effect of lowering serum levels of GH and IGF-I on mortality in acromegaly. Eur J Endocrinol. 2008;159(2):89–95.
  • Bernabeu I, Pico A, Venegas E, et al. Spanish ACROSTUDY group. Safety of long-term treatment with Pegvisomant: analysis of Spanish patients included in global ACROSTUDY. Pituitary. 2016;19(2):127–137. .
  • van der Lely AJ, Hutson RK, Trainer PJ, et al. Long-term treatment of acromegaly with pegvisomant, a growth hormone receptor antagonist. Lancet. 2001;358(9295):1754–1759.
  • Brazzelli M, Cruickshank M, Kilonzo M, et al. Clinical effectiveness and cost-effectiveness of cholecystectomy compared with observation/conservative management for preventing recurrent symptoms and complications in adults presenting with uncomplicated symptomatic gallstones or cholecystitis: a systematic review and economic evaluation. Health Technol Assess. 2014;18(55):1–101.
  • García-Soidán FJ, Villoro R, Merino M, et al. Estado de salud, calidad de vida y utilización de recursos sanitarios de los pacientes con diabetes mellitus en España. Medic Fam. 2017;43(6):416–424.
  • Rowles SV, Prieto L, Badia X, et al. Quality of life (QOL) in patients with acromegaly is severely impaired: use of a novel measure of QOL: acromegaly quality of life questionnaire. J Clin Endocrinol Metab. 2005;90(6):3337–3341.
  • Salomon JA, Vos T, Hogan DR, et al. Common values in assessing health outcomes from disease and injury: disability weights measurement study for the global burden of disease study 2010. Lancet. 2012;380(9859):2129–2143.
  • Ferreira CNRC, Santana CF Acromegaly patients with inadequate response to maximum dose octreotide-lar who progress to treatment with pegvisomant: economic evaluation and incremental budget impact analysis from the public perspective to são paulo state. ISPOR 5th Latin America conference; September 2015; Santiago de Chile: ISPOR; 2015.
  • Llibre-Codina JM, Casado-Gómez MA, Sánchez-de la Rosa R, et al. [Cost of nucleoside analogue reverse transcriptase inhibitor-related toxicity in HIV-1-infected patients]. Enferm Infecc Microbiol Clin. 2007;25(2):98–107.
  • Registro de altas. CIE9 MC CMBD 2013 [Internet]. 2013. [Cited 2018 Nov 04]. Available from: http://pestadistico.inteligenciadegestion.msssi.es
  • Colao A, Ferone D, Marzullo P, et al. Systemic complications of acromegaly: epidemiology, pathogenesis, and management. Endocr Rev. 2004;25(1):102–152.
  • Colao A, Pivonello R, Grasso LF, et al. Determinants of cardiac disease in newly diagnosed patients with acromegaly: results of a 10 year survey study. Eur J Endocrinol. 2011;165(5):713–721.
  • Davi‘ MV, Dalle Carbonare L, Giustina A, et al. Sleep apnoea syndrome is highly prevalent in acromegaly and only partially reversible after biochemical control of the disease. Eur J Endocrinol. 2008;159(5):533–540.
  • Andreu AL, Chiner E, Sancho-Chust JN, et al. Effect of an ambulatory diagnostic and treatment programme in patients with sleep apnoea. Eur Respir J. 2012;39(2):305–312.
  • Ballesta M, Carral F, Olveira G, et al. Economic cost associated with type II diabetes in Spanish patients. Eur J Health Econ. 2006;7(4):270–275.
  • Delgado JF, Oliva J, Llano M, et al. Health care and nonhealth care costs in the treatment of patients with symptomatic chronic heart failure in Spain. Rev Esp Cardiol. 2014;67(8):643–650.
  • Montes-Santiago J, Rodil V, Formiga F, et al. Working group on heart failure and atrial fibrillation of the Spanish Society of Internal Medicine (SEMI). Features and costs of patients admitted for cardiac arrhythmias in Spain. Rev Clin Esp. 2013;213(5):235–239.
  • Sicras-Mainar A, Navarro-Artieda R. [Cost of arterial hypertension according to levels of morbidity in primary care setting]. Med Clin. 2009;133(8):290–295.
  • Freda PU, Gordon MB, Kelepouris N, et al. Long-term treatment with pegvisomant as monotherapy in patients with acromegaly: experience from ACROSTUDY. Endocr Pract. 2015;21(3):264–274. .
  • Eckhardt R, Ulam S, von Neumann J, and the Monte Carlo method. Los Alamos Sci. 1987;15(6):131-146.
  • Muhammad A, van der Lely AJ, Delhanty PJD, et al. Efficacy and safety of switching to pasireotide in patients with acromegaly controlled with pegvisomant and first-generation somatostatin analogues (PAPE study). J Clin Endocrinol Metab. 2018;103(2):586–595.
  • Feola T, Cozzolino A, Simonelli I, et al. Pegvisomant improves glucose metabolism in acromegaly: a meta-analysis of prospective interventional studies. J Clin Endocrinol Metab. 2019. DOI:10.1210/jc.2018-02281
  • Vallejo-Torres L, García-Lorenzo B, Castilla I, et al. Valor Monetario de un Año de Vida Ajustado por Calidad: estimación empírica del coste de oportunidad en el Sistema Nacional de Salud.: ministerio de Sanidad, Servicios Sociales e Igualdad. Servicio de Evaluacio´n del Servicio Canario de la Salud. 2015.
  • Drummond MF, Wilson DA, Kanavos P, et al. Assessing the economic challenges posed by orphan drugs. Int J Technol Assess Health Care. 2007;23(1):36–42.
  • Hughes DA, Tunnage B, Yeo ST. Drugs for exceptionally rare diseases: do they deserve special status for funding? Qjm. 2005;98(11):829–836.
  • Picavet E, Dooms M, Cassiman D, et al. Drugs for rare diseases: influence of orphan designation status on price. Appl Health Econ Health Policy. 2011;9(4):275–279.
  • Maione L, Brue T, Beckers A, et al. French acromegaly registry group. Changes in the management and comorbidities of acromegaly over three decades: the French Acromegaly Registry. Eur J Endocrinol. 2017;176(5):645–655.
  • Margusino-Framiñán L, Pertega-Diaz S, Pena-Bello L, et al. Cost-effectiveness analysis of preoperative treatment of acromegaly with somatostatin analogue on surgical outcome. Eur J Intern Med. 2015;26(9):736–741.
  • Didoni G, Grottol S, Gasco V, et al. Cost-of-illness study in acromegalic patients in Italy. J Endocrinol Invest. 2004;27(11):1034–1039.
  • Luque-Ramírez M, Paramo C. Varela da Costa C, García-Mayor RV. Cost of management of invasive growth hormone-secreting macroadenoma. J Endocrinol Invest. 2007;30(7):541–545.
  • Wilson LS, Shin JL, Ezzat S. Longitudinal assessment of economic burden and clinical outcomes in acromegaly. Endocr Pract. 2001;7(3):170–180.
  • Valentim J, Passos V, Mataveli F, et al. Cost-effectiveness analysis of somatostatin analogues in the treatment of acromegaly in Brazil. Arq Bras Endocrinol Metabol. 2008;52(9):1452–1460.
  • Roset M, Merino-Montero S, Luque-Ramírez M, et al. Spanish group of the OASIS study. Cost of clinical management of acromegaly in Spain. Clin Drug Investig. 2012;32(4):235–245.
  • Leonart LP, Borba HHL, Ferreira VL, et al. Cost-effectiveness of acromegaly treatments: a systematic review. Pituitary. 2018;21(6):642–652.
  • Orlewska E, Stępień R, Orlewska K. Cost-effectiveness of somatostatin analogues in the treatment of acromegaly. Expert Rev Pharmacoecon Outcomes Res. 2019;19(1):15–25.
  • Biermasz NR, Roelfsema F, Pereira AM, et al. Cost-effectiveness of lanreotide Autogel in treatment algorithms of acromegaly. Expert Rev Pharmacoecon Outcomes Res. 2009;9(3):223–234.
  • Shimon I, Adnan Z, Gorshtein A, et al. Efficacy and safety of long-acting pasireotide in patients with somatostatin-resistant acromegaly: a multicenter study. Endocrine. 2018 Nov;62(2):448–455.
  • Duan L, Huang M, Yan H, et al. Cost-effectiveness analysis of two therapeutic schemes in the treatment of acromegaly: a retrospective study of 168 cases. J Endocrinol Invest. 2015;38(7):717–723.