1,140
Views
0
CrossRef citations to date
0
Altmetric
Original Research

Health resource utilization and costs of care for adult patients with relapsed or refractory mantle cell lymphoma in the United States: a retrospective claims analysis

, , , , , , ORCID Icon & show all
Pages 773-787 | Received 24 Mar 2023, Accepted 05 May 2023, Published online: 06 Jun 2023

References

  • Cheah CY, Seymour JF, Wang ML. Mantle cell lymphoma. JCO. 2016;34(11):1256–1269. DOI:10.1200/JCO.2015.63.5904
  • Fu S, Wang M, Lairson DR, et al. Trends and variations in mantle cell lymphoma incidence from 1995 to 2013: a comparative study between Texas and National SEER areas. Oncotarget. 2017;8(68):112516–112529.
  • Fakhri B, Kahl B. Current and emerging treatment options for mantle cell lymphoma. Ther Adv Hematol. 2017;8(8):223–234.
  • Yang KK, Lucas E, Lesher B, et al. A systematic review of the epidemiology and economic burden of mantle cell lymphoma (MCL). Blood. 2019;134(Supplement_1):5831.
  • Zhou Y, Wang H, Fang W, et al. Incidence trends of mantle cell lymphoma in the United States between 1992 and 2004. Cancer. 2008;113(4):791.
  • Arcaini L, Lamy T, Walewski J, et al. Prospective subgroup analyses of the randomized MCL-002 (SPRINT) study: lenalidomide versus investigator’s choice in relapsed or refractory mantle cell lymphoma. Br J Haematol. 2018;180(2):224–235. DOI:10.1111/bjh.15025
  • Cheah CY, Chihara D, Romaguera JE, et al. Patients with mantle cell lymphoma failing ibrutinib are unlikely to respond to salvage chemotherapy and have poor outcomes. Ann Oncol. 2015;26(6):1175–1179. DOI:10.1093/annonc/mdv111
  • Bond DA, Switchenko JM, Villa D, et al. Early relapse identifies MCL patients with inferior survival after intensive or less intensive frontline therapy. Blood Adv. 2015;5(23):5179–5189. DOI:10.1182/bloodadvances.2021004765
  • Vose JM. Mantle cell lymphoma: 2017 update on diagnosis, risk‐stratification, and clinical management. Am J Hematol. 2017;92(8):806–813.
  • Hess G, Dreyling M, Oberic L, et al. Real-world experience among patients with relapsed/refractory mantle cell lymphoma after Bruton tyrosine kinase inhibitor failure in Europe: the SCHOLAR-2 retrospective chart review study. Br J Haematol. 2022;00:1–11.
  • Dreyling M, Shah B, Wu JJ, et al. Efficacy outcomes following treatment with Bruton tyrosine kinase inhibitors (BTKi) for relapsed/refractory mantle cell lymphoma (R/R MCL): a literature-based meta-analysis. Poster presented at ISPOR; May 2022; Washington, DC.
  • National Comprehensive Cancer Network (NCCN). Clinical practice guidelines in oncology: b-cell lymphomas. Version 5.2021. Sep 22, 2021.
  • Flinn IW, van der Jagt R, Kahl BS, et al. Randomized trial of bendamustine-rituximab or R-CHOP/R-CVP in first-line treatment of indolent NHL or MCL: the BRIGHT study. Blood. 2014;123(19):2944–2952. DOI:10.1182/blood-2013-11-531327
  • Kluin-Nelemans HC, Hoster E, Hermine O, et al. Treatment of older patients with mantle-cell lymphoma. N Engl J Med. 2012;367(6):520–531. DOI:10.1056/NEJMoa1200920
  • Lenz G, Dreyling M, Hoster E, et al. Immunochemotherapy with rituximab and cyclophosphamide, doxorubicin, vincristine, and prednisone significantly improves response and time to treatment failure, but not long-term outcome in patients with previously untreated mantle cell lymphoma: results of a prospective randomized trial of the German low grade lymphoma study group (GLSG). JCO. 2005;23:1984–1992.
  • Maddocks K. Update on mantle cell lymphoma. Blood. 2018;132(16):1647–1656.
  • Dreyling M, Jurczak W, Jerkeman M, et al. Ibrutinib versus temsirolimus in patients with relapsed or refractory mantle-cell lymphoma: an international, randomised, open-label, phase 3 study. Lancet. 2016;387(10020):770–778. DOI:10.1016/S0140-6736(15)00667-4
  • Tam CS, Anderson MA, Pott C, et al. Ibrutinib plus venetoclax for the treatment of mantle-cell lymphoma. N Engl J Med. 2018;378(13):1211–1223. DOI:10.1056/NEJMoa1715519
  • Goy A, Sinha R, Williams ME, et al. Single-agent lenalidomide in patients with mantle-cell lymphoma who relapsed or progressed after or were refractory to bortezomib: phase II MCL-001 (EMERGE) study. J Clin Oncol. 2013;31(29):3688–3695. DOI:10.1200/JCO.2013.49.2835
  • Fisher RI, Bernstein SH, Kahl BS, et al. Multicenter phase II study of bortezomib in patients with relapsed or refractory mantle cell lymphoma. J Clin Oncol. 2006;24(30):4867–4874. DOI:10.1200/JCO.2006.07.9665
  • Wang M, Rule S, Zinzani PL, et al. Acalabrutinib in relapsed or refractory mantle cell lymphoma (ACE-LY-004): a single-arm, multicentre, phase 2 trial. Lancet. 2018;391(10121):659–667. DOI:10.1016/S0140-6736(17)33108-2
  • Monga N, Tam C, Garside J. Clinical efficacy and safety of first-line treatments in patients with mantle cell lymphoma: a systematic literature review. Crit Rev In Oncol/Hematol. 2021;158:103212.
  • TECARTUS [package insert]. Santa Monica CA: Kite, A Gilead Company; 2021.
  • JAYPIRCA [package insert]. (IN)polis IN: Lilly USA, LLC; 2023.
  • Kabadi SM, Near A, Wada K, et al. Treatment patterns, adverse events, healthcare resource use and costs among commercially insured patients with mantle cell lymphoma in the United States. Cancer Med. 2019;8(17):7174–7185.
  • Goyal RK, Nagar SP, Kabadi SM, et al. Adverse events, resource use and economic burden associated with mantle cell lymphoma: a real-world assessment of privately insured patients in the US. Leukemia & Lymphoma. Leukemia & Lymphoma. 2018;60(4):955–963. DOI:10.1080/10428194.2018.1509320
  • Quan H, Sundararajan V, Halfon P, et al. Coding algorithms for defining comorbidities in ICD-9-CM and ICD-10 administrative data. Med care. 2005;43(11):1130–1139. DOI:10.1097/01.mlr.0000182534.19832.83
  • Agency for Healthcare Research and Quality. HCUP Chronic Condition Indicator. Healthcare Cost and Utilization Project (HCUP). [Accessed 2022 Oct 6]. Available at. https://www.hcup-us.ahrq.gov/toolssoftware/chronic_icd10/chronic_icd10.jsp
  • Wade RL, Hu HX, Chen JY, et al. Increased treatment cost associated with mantle cell lymphoma disease progression. Haematologica. 2015;100:149.
  • Owen C, Berinstein NL, Chistofiedes A, et al. Review of Bruton tyrosine kinase inhibitors for the treatment of relapsed or refractory mantle cell lymphoma. Curr Oncol. 2019;26(2):e233–240.
  • O’Brien SM, Brown JR, Byrd JC, et al. Monitoring and managing BTK inhibitor treatment-related adverse events in clinical practice. Front Oncol. 2021;11. doi:10.3389/fonc.2021.720704.
  • Wang M, Munoz J, Goy A, et al. KTE-X19 CAR T-cell therapy in relapsed or refractory mantle-cell lymphoma. N Engl J Med. 2020;382(14):1331–1342. DOI:10.1056/NEJMoa1914347
  • Kumar A, Eyre TA, Lewis KL, et al. New Directions for Mantle Cell Lymphoma in 2022. Am Soc Clin Oncol Educ Book. 2022;42(42):614–628. DOI:10.1200/EDBK_349509
  • National Cancer Institute. Financial burden of cancer care. Updated April 2022. Accessed May 2, 2022. https://www.progressreport.cancer.gov/after/economic_burden.