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Review

Antiepileptic drug therapy and recommendations for withdrawal in patients with seizures and epilepsy due to neurocysticercosis

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Pages 1079-1085 | Received 16 Mar 2016, Accepted 24 May 2016, Published online: 08 Jun 2016

References

  • Garcia HH, Nash TE, Del Brutto OH. Clinical symptoms, diagnosis, and treatment of neurocysticercosis. Lancet Neurol. 2014;13(12):1202–1215.
  • Escobar A. The pathology of neurocysticercosis. In: Palacios E, Rodriguez-Carbajal J, Taveras JM, editors. Cysticercosis of the central nervous system. Springfield (IL): Charles C. Thomas; 1983. p. 27–54.
  • Relationship between epilepsy and tropical diseases. Commission on tropical diseases of the international league against epilepsy. Epilepsia. 1994;35(1):89–93.
  • Roman G, Sotelo J, Del Brutto O, et al. A proposal to declare neurocysticercosis an international reportable disease. Bull WHO. 2000;78(3):399–406.
  • Del Brutto OH. Neurocysticercosis. Handb Clin Neurol. 2014;121:1445–1459.
  • Birbeck GL. Epilepsy care in developing countries: part I of II. Epilepsy Curr. 2010;10(4):75–79.
  • Bruno E, Bartoloni A, Zammarchi L, et al. Epilepsy and neurocysticercosis in Latin America: a systematic review and meta-analysis. PLoS Neglect Trop Dis. 2013;7(10):e2480.
  • Ndimubanzi PC, Carabin H, Budke CM, et al. A systematic review of the frequency of neurocyticercosis with a focus on people with epilepsy. PLoS Neglect Trop Dis. 2010;4(11):e870.
  • Croker C, Soriano J, Civen R, et al. Notes from the field: identification of a Taenia tapeworm carrier - Los Angeles County, 2014. MMWR Morb Mortal Wkly Rep. 2015;64(3):74.
  • Newton CR, Preux P-M, Singhi P. Parasitic disorders. Handb Clin Neurol. 2013;112:1139–1152.
  • O’Neal S, Noh J, Wilkins P, et al. Taenia solium tapeworm infection, Oregon, 2006-2009. Emerg Infect Dis. 2011;17(6):1030–1036.
  • O’Neal SE, Flecker RH. Hospitalization frequency and charges for neurocysticercosis, United States, 2003-2012. Emerg Infect Dis. 2015;21(6):969–976. 1983: 27-54.
  • Del Brutto OH. Clinical management of neurocysticercosis. Expert Rev Neurother. 2014;12(4):389–396.
  • Chopra JS, Kaur U, Mahajan RC. Cysticerciasis and epilepsy: a clinical and serological study. Trans R Soc Trop Med Hyg. 1981;75(4):518–520.
  • Garcia HH, Gilman R, Martinez M, et al. Cysticercosis as a major cause of epilepsy in Peru. The Cysticercosis Working Group in Peru (CWG). Lancet. 1993;341(8839):197–200.
  • Montano SM, Villaran MV, Ylquimiche L, et al. Neurocysticercosis: association between seizures, serology, and brain CT in rural Peru. Neurology. 2005;65(2):229–233.
  • Medina MT, Duron RM, Martinez L, et al. Prevalence, incidence, and etiology of epilepsies in rural Honduras: the Salama Study. Epilepsia. 2005;46(1):124–131.
  • Del Brutto OH, Santibanez R, Idrovo L, et al. Epilepsy and neurocysticercosis in Atahualpa: a door-to-door survey in rural coastal Ecuador. Epilepsia. 2005;46(4):583–587.
  • Moyano LM, Saito M, Montano SM, et al. Neurocysticercosis as a cause of epilepsy and seizures in two community-based studies in a cysticercosis-endemic region in Peru. PLoS Neglect Trop Dis. 2014;8(2):e2692.
  • Singh G, Bawa J, Chinna D, et al. Association between epilepsy and cysticercosis and toxocariasis: a population-based case-control study in a slum in India. Epilepsia. 2012;53(12):2203–2208.
  • Prasad KN, Verma A, Srivastava S, et al. An epidemiological study of asymptomatic neurocysticercosis in a pig farming community in northern India. Trans R Soc Trop Med Hyg. 2011;105(9):531–536.
  • Del Brutto OH, Santibanez R, Noboa CA, et al. Epilepsy due to neurocysticercosis: analysis of 203 patients. Neurology. 1992;42(2):389–392.
  • Trelles L. Neurocysticercosis and epilepsy in Peru. Clin Neurol Neurosurg. 1992;94(Suppl):S153–S154.
  • Garcia-Ramos G, Rubio-Donnadieu F. Neurocysticercosis in the adult. In: Palacios E, Rodriguez-Carbajal J, Taveras JM, editors. Cysticercosis of the central nervous system. Springfield (IL): Charles C Thomas; 1983.
  • Earnest MP, Reller LB, Filley CM, et al. Neurocysticercosis in the United States: 35 cases and a review. Rev Infect Dis. 1987;9(5):961–979.
  • Medina MT, Rosas E, Rubio-Donnadieu F, et al. Neurocysticercosis as the main cause of late-onset epilepsy in Mexico. Arch Intern Med. 1990;150(2):325–327.
  • Pradhan S, Kumar R, Gupta RK. Intermittent symptoms in neurocysticercosis: could they be epileptic? Acta Neurol Scand. 2003;107(4):260–266.
  • Alarcon T, Olivares L. [Cerebral cysticercosis. Clinical manifestations in a high prevalence milieu (author’s transl)]. Rev Invest Clin. 1975;27(3):209–215.
  • Mahanty S, Orrego MA, Mayta H, et al. Post-treatment vascular leakage and inflammatory responses around brain cysts in porcine neurocysticercosis. PLoS Neglec Trop Dis. 2015;9(3):e0003577.
  • Nash TE, Mahanty S, Loeb JA, et al. Neurocysticercosis: a natural human model of epileptogenesis. Epilepsia. 2015;56(2):177–183.
  • Garcia HH, Gonzalez AE, Gilman RH. Cysticercosis of the central nervous system: how should it be managed? Curr Opin Infect Dis. 2011;24(5):423–427.
  • Nash TE, Garcia HH. Diagnosis and treatment of neurocysticercosis. Nat Reviews Neurol. 2011;7(10):584–594.
  • Rajshekhar V, Chandy MJ. Validation of diagnostic criteria for solitary cerebral cysticercus granuloma in patients presenting with seizures. Acta Neurol Scand. 1997;96(2):76–81.
  • Del Brutto OH. Single parenchymal brain cysticercus in the acute encephalitic phase: definition of a distinct form of neurocysticercosis with a benign prognosis. J Neurol Neurosurg Psychiatry. 1995;58(2):247–249.
  • Del Brutto VJ, Del Brutto OH, Ochoa E, et al. Single parenchymal brain cysticercus: relationship between age of patients and evolutive stage of parasites. Neurol Res. 2012;34(10):967–970.
  • Grau E, Garrido F, Cañedo L. Calcification of the cysticerci of Taenia solium in the human brain. In: Flisser A, Willms K, Laclette JP, et al., editors. Cysticercosis present state of knowledge and perspectives. New York (NY): Academic Press; 1982. p. 499–516.
  • Ooi WW, Wijemanne S, Thomas CB, et al. Short report: A calcified Taenia solium granuloma associated with recurrent perilesional edema causing refractory seizures: histopathological features. Am J Trop Med Hyg. 2011;85(3):460–463.
  • Nash TE, Bartelt LA, Korpe PS, et al. Calcified neurocysticercus, perilesional edema, and histologic inflammation. Am J Trop Med Hyg. 2014;90(2):318–321.
  • Nash TE, Del Brutto OH, Butman JA, et al. Calcific neurocysticercosis and epileptogenesis. Neurology. 2004;62(11):1934–1938.
  • Nash TE, Pretell EJ, Lescano AG, et al. Perilesional brain oedema and seizure activity in patients with calcified neurocysticercosis: a prospective cohort and nested case-control study. Lancet Neurol. 2008;7(12):1099–1105.
  • Nash TE, Pretell J, Garcia HH. Calcified cysticerci provoke perilesional edema and seizures. Clin Infect Dis. 2001;33(10):1649–1653.
  • Nash TE, Mahanty S, Loeb JA, et al. In response: multifactorial basis of epilepsy in patients with neurocysticercosis. Epilepsia. 2015;56(6):975–976.
  • Sharma M, Singh T, Mathew A. Antiepileptic drugs for seizure control in people with neurocysticercosis. Cochrane Database Syst Rev. 2015;10:CD009027.
  • Nash TE, Gonzales I, Lescano AG, et al. Enhanced steroid dosing reduces seizures during antiparasitic treatment for cysticercosis and early after. Epilepsia. 2014;55(9):1452–1459.
  • Singhi P, Jain V, Khandelwal N. Corticosteroids versus albendazole for treatment of single small enhancing computed tomographic lesions in children with neurocysticercosis. J Child Neurol. 2004;19(5):323–327.
  • Bustos JA, Montoya E, Garcia HH. Cysticercosis working group in P. Residual brain calcifications in neurocysticercosis. Am J Trop Med Hyg. 2008;78(3):363.
  • Agarwal A, Raghav S, Husain M, et al. Epilepsy with focal cerebral calcification: role of magnetization transfer MR imaging. Neurol India. 2004;52(2):197–199.
  • de Souza A, Nalini A, Kovoor JM, et al. Perilesional gliosis around solitary cerebral parenchymal cysticerci and long-term seizure outcome: a prospective study using serial magnetization transfer imaging. Epilepsia. 2011;52(10):1918–1927.
  • Leite JP, Terra-Bustamante VC, Fernandes RM, et al. Calcified neurocysticercotic lesions and postsurgery seizure control in temporal lobe epilepsy. Neurology. 2000;55(10):1485–1491.
  • Bianchin MM, Velasco TR, Coimbra ER, et al. Cognitive and surgical outcome in mesial temporal lobe epilepsy associated with hippocampal sclerosis plus neurocysticercosis: a cohort study. PloS One. 2013;8(4):e60949.
  • Bianchin MM, Velasco TR, Wichert-Ana L, et al. Characteristics of mesial temporal lobe epilepsy associated with hippocampal sclerosis plus neurocysticercosis. Epilepsy Res. 2014;108(10):1889–1895.
  • Del Brutto OH, Engel J Jr., Eliashiv DS, et al. Update on cysticercosis epileptogenesis: the role of the hippocampus. Curr Neurol Neurosc Rep. 2016;16(1):1.
  • Del Brutto OH, Salgado P, Lama J, et al. Calcified neurocysticercosis associates with hippocampal atrophy: a population-based study. Am J Trop Med Hyg. 2015;92(1):64–68.
  • Singh G, Burneo JG, Sander JW. From seizures to epilepsy and its substrates: neurocysticercosis. Epilepsia. 2013;54(5):783–792.
  • Oliveira MC, Martin MG, Tsunemi MH, et al. Small calcified lesions suggestive of neurocysticercosis are associated with mesial temporal sclerosis. Arq Neuropsiquiat. 2014;72(7):510–516.
  • Bianchin MM, Velasco TR, Takayanagui OM, et al. Neurocysticercosis, mesial temporal lobe epilepsy, and hippocampal sclerosis: an association largely ignored. Lancet Neurol. 2006;5(1):20–21.
  • Kahn MS, Kranjac D, Alonzo CA, et al. Prolonged elevation in hippocampal Abeta and cognitive deficits following repeated endotoxin exposure in the mouse. Behav Brain Res. 2012;229(1):176–184.
  • Shimada T, Takemiya T, Sugiura H, et al. Role of inflammatory mediators in the pathogenesis of epilepsy. Med Inflamm. 2014;2014:901902.
  • Kaushal S, Rani A, Chopra SC, et al. Safety and efficacy of clobazam versus phenytoin-sodicum in the antiepileptic treatment of solitary cysticercus granulomas. Neurol India. 2006;54(2):157–160.
  • Vazquez V, Sotelo J. The course of seizures after treatment for cerebral cysticercosis. N Engl J Med. 1992;327(19):696–701.
  • Abou-Khalil B. Levetiracetam in the treatment of epilepsy. Neuropsychiatr Dis Treat. 2008;4(3):507–523.
  • Singh G, Kaushal S, Gupta M, et al. Cutaneous reactions in patients with solitary cysticercus granuloma on phenytoin sodium. J Neurol Neurosurg Psychiatry. 2004;75(2):331–333.
  • Romo ML, Carpio A, Kelvin EA. Routine drug and food interactions during antihelminthic treatment of neurocysticercosis: a reason for the variable efficacy of albendazole and praziquantel? J Clin Pharmacol. 2014;54(4):361–367.
  • Lanchote VL, Garcia FS, Dreossi SA, et al. Pharmacokinetic interaction between albendazole sulfoxide enantiomers and antiepileptic drugs in patients with neurocysticercosis. Ther Drug Monit. 2002;24(3):338–345.
  • Bittencourt PR, Gracia CM, Martins R, et al. Phenytoin and carbamazepine decreased oral bioavailability of praziquantel. Neurology. 1992;42(3 Pt 1):492–496.
  • Lossius MI, Hessen E, Mowinckel P, et al. Consequences of antiepileptic drug withdrawal: a randomized, double-blind study (Akershus Study). Epilepsia. 2008;49(3):455–463.
  • Jacoby A, Johnson A, Chadwick D. Psychosocial outcomes of antiepileptic drug discontinuation. The medical Research Council Antiepileptic Drug Withdrawal Study Group. Epilepsia. 1992;33(6):1123–1131.
  • Braun KP, Schmidt D. Stopping antiepileptic drugs in seizure-free patients. Curr Opin Neurol. 2014;27(2):219–226.
  • Del Brutto OH. Prognostic factors for seizure recurrence after withdrawal of antiepileptic drugs in patients with neurocysticercosis. Neurology. 1994;44(9):1706–1709.
  • Del Brutto OH, Campos X. Discontinuation of antiepileptic drugs in patients with calcified neurocysticercosis. J Epilepsy. 1996;9(4):231–233.
  • Kramer LD. Antihelmintic therapy for neurocysticercosis. Arch Neurol. 1990;47(10):1059.
  • Thussu A, Arora A, Prabhakar S, et al. Acute symptomatic seizures due to single CT lesions: how long to treat with antiepileptic drugs? Neurol India. 2002;50(2):141–144.
  • Gupta M, Agarwal P, Khwaja GA, et al. Randomized prospective study of outcome of short term antiepileptic treatment in small single enhancing CT lesion in brain. Neurol India. 2002;50(2):145–147.
  • Singhi PD, Dinakaran J, Khandelwal N, et al. One vs. two years of anti-epileptic therapy in children with single small enhancing CT lesions. J Trop Pediatr. 2003;49(5):274–278.
  • Rajshekhar V, Jeyaseelan L. Seizure outcome in patients with a solitary cerebral cysticercus granuloma. Neurology. 2004;62(12):2236–2240.
  • Verma A, Misra S. Outcome of short-term antiepileptic treatment in patients with solitary cerebral cysticercus granuloma. Acta Neurol Scand. 2006;113(3):174–177.

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