Medication-overuse headache. Despite the advances in understanding it, treatment evidence still lacks

References

• Kristoffersen ES, Lundqvist C. Medication-overuse headache: a review. J Pain Res. 2014;7:367–378.
   PubMed Web of Science ®Google Scholar
• Scher AI, Stewart WF, Liberman J, et al. Prevalence of frequent headache in a population sample. Headache. 2001;38:497–506.
   Web of Science ®Google Scholar
• Andrasik F, Grazzi L, Usai S, et al. Disability in chronic migraine with medication overuse: treatment effects through 5 years. Cephalalgia. 2010;30:610–614.
   PubMed Web of Science ®Google Scholar
• Lipton RB. Risk factors for and management of medication overuse headache. Continuum (Minneap Minn). 2015;21:1118–1131.
   PubMedGoogle Scholar
• Schwedt T, Chong C. Medication overuse headache: pathophysiological insights from structural and functional brain MRI research. Headache. 2017;57:1173–1178.
   PubMed Web of Science ®Google Scholar
• Russel MB, Lundqvist C. Prevention and management of medication overuse headache. Curr Opin Neurol. 2012;25:290–295.
   PubMed Web of Science ®Google Scholar
• Tassorelli C, Jensen R, Allena M, et al.; and the COMOESTAS Consortium. A consensus protocol for the management of medication-overuse headache: evaluation in a multicentric, multinational study. Cephalalgia. 2014;34:645–655.
   PubMed Web of Science ®Google Scholar
• Krymchantowski AV, Tepper SJ, Jevoux C, et al. Medication-overuse headache: differences between daily and near-daily headache patients. Brain Sci. 2016;6(4):30.
   PubMed Web of Science ®Google Scholar
• Lai TH, Chou KH, Fuh JL, et al. Gray matter changes related to medication overuse in patients with chronic migraine. Cephalalgia. 2016;36:1324–1333.
   PubMed Web of Science ®Google Scholar
• Riederer F, Marti M, Luechinger R, et al. Gray matter changes associated with medication-overuse headache: correlations with disease related disability and anxiety. World J Biol Psychiatry. 2012;13:517–525.
   PubMed Web of Science ®Google Scholar
• Chanraud S, Di Scala G, Dilharreguy B, et al. Brain functional connectivity and morphology changes in medication-overuse headache: clue for dependence-related processes? Cephalalgia. 2014;34:605–615.
   PubMed Web of Science ®Google Scholar
• Munksgaard SB, Bendtsen L, Jensen R. Treatment-resistant medication overuse headache can be cured. Headache. 2012;52:1120–1129.
   PubMed Web of Science ®Google Scholar
• Krymchantowski AV, Tepper SJ, Jevoux C, et al. Medication-overuse headache: protocols and outcomes in 149 consecutive patients in a tertiary Brazilian center. Headache. 2017;57:87–96.
   PubMed Web of Science ®Google Scholar
• Evers S, Jensen R. Treatment of medication overuse headache – guideline of the EFNS headache panel. Eur J Neurol. 2011;18:1115–1121.
   PubMed Web of Science ®Google Scholar
• Mei D, Ferraro D, Zelano G, et al. Topiramate and triptans revert chronic migraine with medication overuse to episodic migraine. Clin Neuropharmacol. 2006;29:269–275.
   PubMed Web of Science ®Google Scholar
• Sandrini G, Perrotta A, Tassorelli C, et al. Botulinum toxin type-A in the prophylactic treatment of medication-overuse headache: a multicenter, double-blind, randomized, placebo-controlled, parallel-group study. J Headache Pain. 2011;12:427–433.
   PubMed Web of Science ®Google Scholar
• Silberstein SD, Blumenfeld AM, Cady RK, et al. OnabotulinumtoxinA for treatment of chronic migraine: PREEMPT 24-week pooled subgroup analysis of patients who had acute headache medication overuse at baseline. J Neurol Sci. 2013;331:48–56.
   PubMed Web of Science ®Google Scholar
• Yang CP, Chang MH, Liu PE, et al. Acupuncture versus topiramate in chronic migraine prophylaxis: a randomized clinical trial. Cephalalgia. 2011;31:1510–1521.
   PubMed Web of Science ®Google Scholar
• Serra G, Marchioretto F. Occipital nerve stimulation for chronic migraine: a randomized trial. Pain Physician. 2012;15:245–253.
   PubMed Web of Science ®Google Scholar
• Proietti Cecchini A, Leone M, Manzoni GC, et al. Drug-resistant chronic migraine: the Italian GON project. Neurol Sci. 2012;33(suppl 1):33–35.
   PubMed Web of Science ®Google Scholar
• Tobin JA, Flitman SS. Occipital nerve blocks: effect of symptomatic medication: overuse and headache type on failure rate. Headache. 2009;29:1479–1485.
   Web of Science ®Google Scholar
• Grazzi L, D’Amico D, Raggi A, et al. Mindfulness and pharmacological prophylaxis have comparable effect on biomarkers of inflammation and clinical indexes in chronic migraine with medication overuse: results at 12 months after withdrawal. Neurol Sci. 2017;38(Suppl 1):173–175.
   PubMed Web of Science ®Google Scholar
• Tepper SJ, Ashina M, Reuter U, et al. Safety and efficacy or erenumab for preventive treatment of chronic migraine: a randomized, double-blind, placebo-controlled phase 2 trial. Lancet Neurol. 2017;16:425–434.
   PubMed Web of Science ®Google Scholar
• Levin M, Schulman E. Refractory migraine. Definition and classification. In: Schulman E, Levin M, Lake A III, et al., editors. Refractory migraine. Mechanisms and management. New York, NY: Oxford University Press; 2010. p. 19.
   Google Scholar
• Chiang CC, Schwedt T, Wang SJ, et al. Treatment of medication-overuse headache: a systematic review. Cephalalgia. 2016;36:371–386.
   PubMed Web of Science ®Google Scholar
• Krymchantowski AV, Jevoux C. The pharmacological treatment of migraine in Brazil. Headache. 2015;55(suppl 1):51–58.
   PubMed Web of Science ®Google Scholar
• Kristoffersen ES, Straand J, Benth JŠ, et al. Predictors of successful primary care detoxification treatment for medication-overuse headache. Acta Neurol Scand. 2017 Mar 28. doi: 10.1111/ane.12759. [Epub ahead of print].
   Google Scholar
• Oterino A, Ramon C, Pascual J. Experience with onabotulinumtoxinA (BOTOX) in chronic refractory migraine: focus on severe attacks. J Headache Pain. 2011;12:235–238.
   PubMed Web of Science ®Google Scholar