1,109
Views
20
CrossRef citations to date
0
Altmetric
Review

Management of post-stroke mood and emotional disturbances

Pages 1179-1188 | Received 02 Aug 2017, Accepted 18 Oct 2017, Published online: 26 Oct 2017

References

  • Hackett ML, Kohler S, O’Brien JT, et al. Neuropsychiatric outcomes of stroke. Lancet Neurol. 2014;13:525–534.
  • Ayerbe L, Ayis S, Crichton S, et al. The long-term outcomes of depression up to 10 years after stroke; the South London Stroke Register. J Neurol Neurosurg Psychiatry. 2014;85:514–521.
  • Hinkle JL, Becker KJ, Kim JS, et al. Poststroke fatigue: emerging evidence and approaches to management: a scientific statement for healthcare professionals from the American Heart Association. Stroke. 2017;48:e159–e170.
  • Noh SM, Chung SJ, Kim KK, et al. Emotional disturbance in cadasil: its impact on quality of life and caregiver burden. Cerebrovasc Dis. 2014;37:188–194.
  • Ferro JM, Caeiro L, Santos C. Poststroke emotional and behavior impairment: a narrative review. Cerebrovasc Dis. 2009;27(Suppl 1):197–203.
  • Towfighi A, Ovbiagele B, El Husseini N, et al. Poststroke depression: a scientific statement for healthcare professionals from the American Heart Association/American Stroke Association. Stroke. 2017;48:e30–e43.
  • van Dijk MJ, de Man-van Ginkel JM, Hafsteinsdóttir TB, et al. Identifying depression post-stroke in patients with aphasia: a systematic review of the reliability, validity and feasibility of available instruments. Clin Rehabil. 2016;30:795–810.
  • Hackett ML, Pickles K. Part I: frequency of depression after stroke: an updated systematic review and meta-analysis of observational studies. Int J Stroke. 2014;9:1017–1025.
  • Kim JS, Lee EJ, Chang DI, et al. Efficacy of early administration of escitalopram on depressive and emotional symptoms and neurological dysfunction after stroke: a multicentre, double-blind, randomised, placebo-controlled study. Lancet Psychiatry. 2017;4:33–41.
  • Robinson RG, Jorge RE. Post-stroke depression: a review. Am J Psychiatry. 2016;173:221–231.
  • Wei N, Yong W, Li X, et al. Post-stroke depression and lesion location: a systematic review. J Neurol. 2015;262:81–90.
  • Gainotti G, Marra C. Determinants and consequences of post-stroke depression. Curr Opin Neurol. 2002;15:85–89.
  • Mak KK, Kong WY, Mak A, et al. Polymorphisms of the serotonin transporter gene and post-stroke depression: a meta-analysis. J Neurol Neurosurg Psychiatry. 2013;84:322–328.
  • Hackett ML, Anderson CS, House A, et al. Interventions for treating depression after stroke. Cochrane Database Syst Rev. 2008;CD003437.
  • Sanchez C, Reines EH, Montgomery SA. A comparative review of escitalopram, paroxetine, and sertraline: are they all alike? Int Clin Psychopharmacol. 2014;29:185–196.
  • Mandrioli R, Protti M, Mercolini L. New-generation, non-SSRI antidepressants: therapeutic drug monitoring and pharmacological interactions. Part 1: SNRIS,SMSS,SARIS. Curr Med Chem. 2017 Jul 12. [Epub ahead of print. DOI:10.2174/0929867324666170712165042
  • Miller EL, Murray L, Richards L, et al. Comprehensive overview of nursing and interdisciplinary rehabilitation care of the stroke patient: a scientific statement from the American Heart Association. Stroke. 2010;41:2402–2448.
  • Quinn TJ, Paolucci S, Sunnerhagen KS, et al.; European Stroke Organisation Executive C, Committee ESOW. Evidence-based stroke r-ehabilitation: an expanded guidance document from the European Stroke Organisation (eso) guidelines for management of ischaemic stroke and transient ischaemic attack 2008. J Rehabil Med. 2009;41:99–111.
  • Hackett ML, Anderson CS, House A, et al. Interventions for preventing depression after stroke. Cochrane Database Syst Rev. 2008:Cd003689.
  • Robinson RG, Jorge RE, Moser DJ, et al. Escitalopram and problem-solving therapy for prevention of poststroke depression: a randomized controlled trial. JAMA. 2008;299:2391–2400.
  • Tsai CS, Wu CL, Chou SY, et al. Prevention of poststroke depression with milnacipran in patients with acute ischemic stroke: a double-blind randomized placebo-controlled trial. Int Clin Psychopharmacol. 2011;26:263–267.
  • Uher R, Maier W, Hauser J, et al. Differential efficacy of escitalopram and nortriptyline on dimensional measures of depression. Br J Psychiatry. 2009;194:252–259.
  • Mitchell PH, Veith RC, Becker KJ, et al. Brief psychosocial-behavioral intervention with antidepressant reduces poststroke depression significantly more than usual care with antidepressant: living well with stroke: randomized, controlled trial. Stroke. 2009;40:3073–3078.
  • Thomas SA, Walker MF, Macniven JA, et al. Communication and Low Mood (CALM): a randomized controlled trial of behavioural therapy for stroke patients with aphasia Clin Rehabil. 2013;27:398–408.
  • Kohen R, Cain KC, Buzaitis A, et al. Response to psychosocial treatment in poststroke depression is associated with serotonin transporter polymorphisms. Stroke. 2011;42:2068–2070.
  • Jorge RE, Moser DJ, Acion L, Robinson RG. Treatment of vascular depression using repetitive transcranial magnetic stimulation. Arch Gen Psychiatry. 2008;65:268–276.
  • Rumi DO, Gattaz WF, Rigonatti SP, et al. Transcranial magnetic stimulation accelerates the antidepressant effect of amitriptyline in severe depression: a double-blind placebo-controlled study. Biol Psychiatry. 2005;57:162–166.
  • Kalra L, Evans A, Perez I, et al. Training carers of stroke patients: randomised controlled trial. BMJ (Clinical Research Ed). 2004;328:1–5.
  • Sagen U, Vik TG, Moum T, et al. Screening for anxiety and depression after stroke: comparison of the hospital anxiety and depression scale and the Montgomery and Asberg depression rating scale. J Psychosom Res. 2009;67:325–332.
  • Burvill PW, Johnson GA, Jamrozik KD, et al. Anxiety disorders after stroke: results from the Perth community stroke study. Br J Psychiatry. 1995;166:328–332.
  • Astrom M. Generalized anxiety disorder in stroke patients. A 3-year longitudinal study. Stroke. 1996;27:270–275.
  • Fure B, Wyller TB, Engedal K, et al. Emotional symptoms in acute ischemic stroke. Int J Geriatr Psychiatry. 2006;21:382–387.
  • De Wit L, Putman K, Baert I, et al. Anxiety and depression in the first six months after stroke. A longitudinal multicentre study. Disabil Rehabil. 2008;30:1858–1866.
  • Lincoln NB, Brinkmann N, Cunningham S, et al. Anxiety and depression after stroke: a 5 year follow-up. Disabil Rehabil. 2013;35:140–145.
  • Ayerbe L, Ayis SA, Crichton S, et al. Natural history, predictors and associated outcomes of anxiety up to 10 years after stroke: the South London Stroke Register. Age Ageing. 2014;43:542–547.
  • Menlove L, Crayton E, Kneebone I, et al. Predictors of anxiety after stroke: a systematic review of observational studies. J Stroke Cerebrovasc Dis. 2015;24:1107–1117.
  • Starkstein SE, Cohen BS, Fedoroff P, et al. Relationship between anxiety disorders and depressive disorders in patients with cerebrovascular injury. Arch Gen Psychiatry. 1990;47:246–251.
  • Campbell Burton CA, Murray J, Holmes J, et al. Frequency of anxiety after stroke: a systematic review and meta-analysis of observational studies. Int J Stroke. 2013;8:545–559.
  • de Weerd L, Rutgers WA, Groenier KH, et al. Perceived wellbeing of patients one year post stroke in general practice–recommendations for quality aftercare. BMC Neurol. 2011;11:2–10.
  • Greenwood N, Mackenzie A. An exploratory study of anxiety in carers of stroke survivors. J Clin Nurs. 2010;19:2032–2038.
  • Knapp P, Campbell Burton CA, Holmes J, et al. Interventions for treating anxiety after stroke. Cochrane Database Syst Rev. 2017;5:Cd008860.
  • Kim JS, Bashford G, Murphy TK, et al. Safety and efficacy of pregabalin in patients with central post-stroke pain. Pain. 2011;152:1018–1023.
  • Kneebone II, Jeffries FW. Treating anxiety after stroke using cognitive-behaviour therapy: two cases. Neuropsychol Rehabil. 2013;23:798–810.
  • Golding K, Kneebone I, Fife-Schaw C. Self-help relaxation for post-stroke anxiety: a randomised, controlled pilot study. Clinical Rehabilitation. 2016;30:174–180.
  • Boyd JE, Lanius RA, Mckinnon MC. Mindfulness-based treatments for posttraumatic stress disorder: a review of the treatment literature and neurobiological evidence. J Psychiatry Neurosci. 2017;426:170021. [Epub ahead of print]. DOI:10.1503/jpn.170021
  • Kim JS, Choi-Kwon S. Disturbances in the voluntary control of emotional expression afer stroke. In: Ferro JM, editor. Neuropsychiatric symptoms of cerebrovascular diseases. Springer; 2013. p. 131–160.
  • House A, Dennis M, Molyneux A, et al. Emotionalism after stroke. BMJ (Clinical Research Ed). 1989;298:991–994.
  • Kim JS, Choi-Kwon S. Poststroke depression and emotional incontinence: correlation with lesion location. Neurology. 2000;54:1805–1810.
  • Kim JS. Pathologic laughter after unilateral stroke. J Neurol Sci. 1997;148:121–125.
  • Andersen G, Vestergaard K, Riis JO. Citalopram for post-stroke pathological crying. Lancet. 1993;342:837–839.
  • Brown KW, Sloan RL, Pentland B. Fluoxetine as a treatment for post-stroke emotionalism. Acta Psychiatr Scand. 1998;98:455–458.
  • Burns A, Russell E, Stratton-Powell H, et al. Sertraline in stroke-associated lability of mood. Int J Geriatr Psychiatry. 1999;14:681–685.
  • Murray V, von Arbin M, Bartfai A, et al. Double-blind comparison of sertraline and placebo in stroke patients with minor depression and less severe major depression. J Clin Psychiatry. 2005;66:708–716.
  • Choi-Kwon S, Han SW, Kwon SU, et al. Fluoxetine treatment in poststroke depression, emotional incontinence, and anger proneness: a double-blind, placebo-controlled study. Stroke. 2006;37:156–161.
  • Ohkawa S, Mori E, Yamadori A. [Treatment of pathological laughing with amitriptyline]. Rinsho Shinkeigaku. 1989;29:1183–1185.
  • Robinson RG, Parikh RM, Lipsey JR, et al. Pathological laughing and crying following stroke: validation of a measurement scale and a double-blind treatment study. Am J Psychiatry. 1993;150:286–293.
  • Hackett ML, Yang M, Anderson CS, et al. Pharmaceutical interventions for emotionalism after stroke. Cochrane Database Syst Rev. 2010;CD003690.
  • Moller M, Andersen G. Inhibition of selective noradrenergic reuptake as treatment of pathological laughter. J Clin Psychopharmacol. 2007;27:108–110.
  • Smith AG, Montealegre-Orjuela M, Douglas JE, et al. Venlafaxine for pathological crying after stroke. J Clin Psychiatry. 2003;64:731–732.
  • Kim SW, Shin IS, Kim JM, et al. Mirtazapine treatment for pathological laughing and crying after stroke. Clin Neuropharmacol. 2005;28:249–251.
  • Ramasubbu R. Lamotrigine treatment for post-stroke pathological laughing and crying. Clin Neuropharmacol. 2003;26:233–235.
  • Udaka F, Yamao S, Nagata H, et al. Pathologic laughing and crying treated with levodopa. Arch Neurol. 1984;41:1095–1096.
  • Wolf JK, Santana HB, Thorpy M. Treatment of “emotional incontinence” with levodopa. Neurology. 1979;29:1435–1436.
  • Peeters M, Maloteaux JM, Hermans E. Distinct effects of amantadine and memantine on dopaminergic transmission in the rat striatum. Neurosci Lett. 2003;343:205–209.
  • Peeters M, Romieu P, Maurice T, et al. Involvement of the sigma 1 receptor in the modulation of dopaminergic transmission by amantadine. Eur J Neurosci. 2004;19:2212–2220.
  • Brooks BR, Thisted RA, Appel SH, et al. Treatment of pseudobulbar affect in ALS with dextromethorphan/quinidine: a randomized trial. Neurology. 2004;63:1364–1370.
  • Panitch HS, Thisted RA, Smith RA, et al. Randomized, controlled trial of dextromethorphan/quinidine for pseudobulbar affect in multiple sclerosis. Ann Neurol. 2006;59:780–787.
  • Patatanian E, Casselman J. Dextromethorphan/quinidine for the treatment of pseudobulbar affect. Consult Pharm. 2014;29:264–269.
  • Pioro EP, Brooks BR, Cummings J, et al. Dextromethorphan plus ultra low-dose quinidine reduces pseudobulbar affect. Ann Neurol. 2010;68:693–702.
  • Kim JS, Choi S, Kwon SU, et al. inability to control anger or aggression after stroke. Neurology. 2002;58:1106–1108.
  • Aybek S, Carota A, Ghika-Schmid F, et al. Emotional behavior in acute stroke: the lausanne emotion in stroke study. Cogn Behav Neurol. 2005;18:37–44.
  • Chan KL, Campayo A, Moser DJ, et al. Aggressive behavior in patients with stroke: association with psychopathology and results of antidepressant treatment on aggression. Arch Phys Med Rehabil. 2006;87:793–798.
  • Greenop KR, Almeida OP, Hankey GJ, et al. Premorbid personality traits are associated with post-stroke behavioral and psychological symptoms: a three-month follow-up study in perth, western australia. Int psychogeriatrics/IPA. 2009;21:1063–1071.
  • Santos CO, Caeiro L, Ferro JM, et al. Anger, hostility and aggression in the first days of acute stroke. Eur J Neurol. 2006;13:351–358.
  • Choi-Kwon S, Han K, Cho KH, et al. Factors associated with post-stroke anger proneness in ischaemic stroke patients. Eur J Neurol. 2013;20:1305–1310.
  • Rosa PB, Orquiza B, Rocha FB, et al. Anger and stroke: a potential association that deserves serious consideration. Acta Neuropsychiatrica. 2016;28:346–351.
  • Toscano M, Vigano A, Puledda F, et al. Serotonergic correlation with anger and aggressive behavior in acute stroke patients: an intensity dependence of auditory evoked potentials (idap) study. Eur Neurol. 2014;72:186–192.
  • Fleminger S, Greenwood RJ, Oliver DL. Pharmacological management for agitation and aggression in people with acquired brain injury. Cochrane Database Syst Rev. 2006;Cd003299.
  • Glenn MB, Wroblewski B, Parziale J, et al. Lithium carbonate for aggressive behavior or affective instability in ten brain-injured patients. Am J Phys Med Rehabil. 1989;68:221–226.
  • Chang K, Zhang H, Xia Y, et al. Testing the effectiveness of knowledge and behavior therapy in patients of hemiplegic stroke. Top Stroke Rehabil. 2011;18:525–535.
  • Choi-Kwon S, Kim JS. Poststroke fatigue: an emerging, critical issue in stroke medicine. Int J Stroke. 2011;6:328–336.
  • Ponchel A, Bombois S, Bordet R, et al. Factors associated with poststroke fatigue: a systematic review. Stroke Res Treat. 2015;2015:347920.
  • Drummond A, Hawkins L, Sprigg N, et al. The Nottingham Fatigue after Stroke (NotFAST) study: factors associated with severity of fatigue in stroke patients without depression. Clinical Rehabilitation. 2017;1–10.
  • Tseng BY, Billinger SA, Gajewski BJ, et al. Exertion fatigue and chronic fatigue are two distinct constructs in people post-stroke. Stroke. 2010;41:2908–2912.
  • Kim JS. Post-stroke mood and emotional disturbances: pharmacological therapy based on mechanisms. J Stroke. 2016;18:244–255.
  • Choi-Kwon S, Han SW, Kwon SU, et al. Poststroke fatigue: characteristics and related factors. Cerebrovasc Dis. 2005;19:84–90.
  • Christensen D, Johnsen SP, Watt T, et al. Dimensions of post-stroke fatigue: a two-year follow-up study. Cerebrovasc Dis. 2008;26:134–141.
  • Ormstad H, Aass HC, Amthor KF, et al. Serum cytokine and glucose levels as predictors of poststroke fatigue in acute ischemic stroke patients. J Neurol. 2011;258:670–676.
  • Choi-Kwon S, Ko M, Jun SE, et al. Post-stroke fatigue may be associated with the promoter region of a monoamine oxidase a gene polymorphism. Cerebrovasc Dis. 2017;43:54–58.
  • Choi-Kwon S, Choi J, Kwon SU, et al. Fluoxetine is not effective in the treatment of post-stroke fatigue: a double-blind, placebo-controlled study. Cerebrovasc Dis. 2007;23:103–108.
  • Karaiskos D, Tzavellas E, Spengos K, et al. Duloxetine versus citalopram and sertraline in the treatment of poststroke depression, anxiety, and fatigue. J Neuropsychiatry Clin Neurosci. 2012;24:349–353.
  • Costantini A, Pala MI, Catalano ML, et al. High-dose thiamine improves fatigue after stroke: a report of three cases. J Altern complement Med (New York, NY) 2014;20:683–685.
  • Boiko AN, Lebedeva AV, Shchukin IA, et al. Emotional disorders and quality of life in patients with post stroke asthenia. Zhurnal nevrologii i psikhiatrii imeni SS Korsakova. 2013;113:27–33.
  • Wu S, Kutlubaev MA, Chun HY, et al. Interventions for post-stroke fatigue. Cochrane Database Syst Rev. 2015;Cd007030.
  • Brioschi A, Gramigna S, Werth E, et al. Effect of modafinil on subjective fatigue in multiple sclerosis and stroke patients. Eur Neurol. 2009;62:243–249.
  • Poulsen MB, Damgaard B, Zerahn B, et al. Modafinil may alleviate poststroke fatigue: a randomized, placebo-controlled, double-blinded trial. Stroke. 2015;46:3470–3477.
  • Bivard A, Lillicrap T, Krishnamurthy V, et al. MIDAS (modafinil in debilitating fatigue after stroke): a randomized, double-blind, placebo-controlled, cross-over trial. Stroke. 2017;48:1293–1298.
  • Billinger SA, Arena R, Bernhardt J, et al. Physical activity and exercise recommendations for stroke survivors: a statement for healthcare professionals from the american heart association/american stroke association. Stroke. 2014;45:2532–2553.
  • Johansson B, Biuhr H, Ronnback L. Mindfulness-based stress reduction (MBSR) improves long-term mental fatigue after stroke or traumatic brain injury. Brain Inj. 2012;26:1621–1628.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.