Noninvasive brain stimulation combined with exercise in chronic pain: a systematic review and meta-analysis

References

• Goldberg DS, McGee SJ. Pain as a global public health priority. BMC Public Health. 2011 Oct;6(11):770.
   Google Scholar
• SJaO C. Chronic pain: how to approach these 3 common conditions. J Fam Pract. 2017;66(3):145–157.
   PubMed Web of Science ®Google Scholar
• Torrance N, Ferguson JA, Afolabi E, et al. Neuropathic pain in the community: more under-treated than refractory?. Pain. 2013 May ;154(5):690–9.
   Google Scholar
• Lefaucheur JP, Antal A, Ayache SS, et al. Evidence-based guidelines on the therapeutic use of transcranial direct current stimulation (tDCS). Clin Neurophysiol. 2017 Jan;128(1):56–92.
   PubMed Web of Science ®Google Scholar
• Lefaucheur J-P, André-Obadia N, Antal A, et al. Evidence-based guidelines on the therapeutic use of repetitive transcranial magnetic stimulation (rTMS). Clin Neurophysiol. 2014 Jan 11;125(11):2150–2206.
   PubMed Web of Science ®Google Scholar
• DosSantos MF, Martikainen IK, Nascimento TD, et al. Building up analgesia in humans via the endogenous μ-opioid system by combining placebo and active tDCS: a preliminary report. Plos One. 2014;9(7):e102350.
   PubMed Web of Science ®Google Scholar
• DosSantos MF, Oliveira AT, Ferreira N, et al. The contribution of endogenous modulatory systems to TMS- and tDCS-induced analgesia: evidence from PET studies. Pain Res Manag. 2018;2018:14.
   Web of Science ®Google Scholar
• Garcia-Larrea L, Peyron R, Mertens P, et al. Positron emission tomography during motor cortex stimulation for pain control. Stereotact Funct Neurosurg. 1997;68(1–4 Pt 1):141–148.
   PubMed Web of Science ®Google Scholar
• Garcia-Larrea L, Peyron R, Mertens P, et al. Electrical stimulation of motor cortex for pain control: a combined PET-scan and electrophysiological study. Pain. 1999 Nov;83(2):259–273.
   PubMed Web of Science ®Google Scholar
• Gutmann B, Mierau A, Hulsdunker T, et al. Effects of physical exercise on individual resting state EEG alpha peak frequency. Neural Plast. 2015;2015:717312. .
   Google Scholar
• Sato G, Osumi M, Morioka S. Effects of wheelchair propulsion on neuropathic pain and resting electroencephalography after spinal cord injury. J Rehabil Med. 2017 Jan;49(2):136–143.
   PubMed Web of Science ®Google Scholar
• Walton KDLR. Central pain as a thalamocortical dysrhythmia: a thalamic efference disconnection? In: Kruger LLA, editor. Translational pain research: from mouse to man. Boca Raton (FL): CRC Press/Taylor & Francis; 2010. Chapter 13: 301–314.
   Google Scholar
• Stagg CJ, Antal A, Nitsche MA. Physiology of transcranial direct current stimulation. J Ect. 2018 Sep;34(3):144–152.
   PubMed Web of Science ®Google Scholar
• Bestmann S. The physiological basis of transcranial magnetic stimulation. Trends Cogn Sci. 2008 Mar;12(3):81–83.
   PubMed Web of Science ®Google Scholar
• Woods AJ, Antal A, Bikson M, et al. A technical guide to tDCS, and related non-invasive brain stimulation tools. Clin Neurophysiol. 2016 Feb;127(2):1031–1048.
   PubMed Web of Science ®Google Scholar
• Valero-Cabre A, Amengual JL, Stengel C, et al. Transcranial magnetic stimulation in basic and clinical neuroscience: A comprehensive review of fundamental principles and novel insights. Neurosci Biobehav Rev. 2017 Dec;83:381–404.
   PubMed Web of Science ®Google Scholar
• Neva JA-O, Brown KE, Mang CS, et al. An acute bout of exercise modulates both intracortical and interhemispheric excitability. Eur J Neurosci. 2017 May;45(10):1343–1355. .
   Google Scholar
• Tajerian M, Clark JD. Nonpharmacological Interventions in targeting pain-related brain plasticity. Neural Plast. 2017;2017:2038573.
   PubMed Web of Science ®Google Scholar
• Wakaizumi K, Kondo T, Hamada Y, et al. Involvement of mesolimbic dopaminergic network in neuropathic pain relief by treadmill exercise: A study for specific neural control with Gi-DREADD in mice. Mol Pain. 2016;12:1–11.
   Web of Science ®Google Scholar
• Geneen LJ, Moore RA, Clarke C, et al. Physical activity and exercise for chronic pain in adults: an overview of cochrane reviews. Cochrane Database Syst Rev. 2017 Jan;14(1):Cd011279.
   Google Scholar
• Brosseau L, Taki J, Desjardins B, et al. The Ottawa panel clinical practice guidelines for the management of knee osteoarthritis. Part two: strengthening exercise programs. Clin Rehabil. 2017 May;31(5):596–611.
   PubMed Web of Science ®Google Scholar
• Rice D, Nijs J, Kosek E, et al. Exercise-induced hypoalgesia in pain-free and chronic pain populations: state of the art and future directions. J Pain. 2019 Nov;20(11):1249–1266. .
   PubMed Web of Science ®Google Scholar
• Steinberg F, Pixa NH, Fregni F. A review of acute aerobic exercise and transcranial direct current stimulation effects on cognitive functions and their potential synergies [Review]. Front Hum Neurosci. 2019 January 11;12(534). DOI:10.3389/fnhum.2018.00534.
   PubMedGoogle Scholar
• Vaz PG, Salazar A, Stein C, et al. Noninvasive brain stimulation combined with other therapies improves gait speed after stroke: a systematic review and meta-analysis. Top Stroke Rehabil. 2019 Apr;26(3):201–213.
   PubMed Web of Science ®Google Scholar
• Rice D, Nijs J, Kosek E, et al. Exercise-induced hypoalgesia in pain-free and chronic pain populations: state of the art and future directions. J Pain. 2019;20(11):1249–1266.
   PubMed Web of Science ®Google Scholar
• Higgins JPT, Altman DG, Gøtzsche PC, et al. The cochrane collaboration’s tool for assessing risk of bias in randomised trials. BMJ. 2011;343:d5928.
   PubMed Web of Science ®Google Scholar
• Moher D, Liberati A, Tetzlaff J, et al. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. PLoS Med. 2009;6(7):e1000097.
   PubMed Web of Science ®Google Scholar
• Jadad AR, Moore RA, Carroll D, et al. Assessing the quality of reports of randomized clinical trials: is blinding necessary? Control Clin Trials. 1996 Feb;17(1):1–12.
   Google Scholar
• O’Connell NE, Marston L, Spencer S, et al. Non-invasive brain stimulation techniques for chronic pain. Cochrane Database Syst Rev. 2018 Apr;13(4):Cd008208.
   Google Scholar
• Lakens D. Calculating and reporting effect sizes to facilitate cumulative science: a practical primer for t-tests and ANOVAs. Front Psychol. 2013 Nov;26(4):863.
   Google Scholar
• Dworkin RH, Turk DC, Wyrwich KW, et al. Interpreting the clinical importance of treatment outcomes in chronic pain clinical trials: IMMPACT recommendations. J Pain. 2008 Feb;9(2):105–121.
   PubMed Web of Science ®Google Scholar
• DerSimonian R, Laird N. Meta-analysis in clinical trials. Control Clin Trials. 1986 Sep;7(3):177–88.
   Google Scholar
• Chang WJ, Bennell KL, Hodges PW, et al. Addition of transcranial direct current stimulation to quadriceps strengthening exercise in knee osteoarthritis: A pilot randomised controlled trial. PLoS One. 2017;12(6):e0180328.
   PubMed Web of Science ®Google Scholar
• Oliveira LB, Lopes TS, Soares C, et al. Transcranial direct current stimulation and exercises for treatment of chronic temporomandibular disorders: a blind randomised-controlled trial. J Oral Rehabil. 2015 Oct;42(10):723–732.
   PubMed Web of Science ®Google Scholar
• Sakrajai P, Janyacharoen T, Jensen MP, et al. Pain reduction in myofascial pain syndrome by anodal transcranial direct current stimulation combined with standard treatment: a randomized controlled study. Clin J Pain. 2014 Dec;30(12):1076–1083.
   PubMed Web of Science ®Google Scholar
• Straudi S, Buja S, Baroni A, et al. The effects of transcranial direct current stimulation (tDCS) combined with group exercise treatment in subjects with chronic low back pain: a pilot randomized control trial. Clin Rehabil. 2018 Oct;32(10):1348–1356.
   PubMed Web of Science ®Google Scholar
• Riberto M, Marcon Alfieri F, de Benedetto Pacheco KM, et al. Efficacy of transcranial direct current stimulation coupled with a multidisciplinary rehabilitation program for the treatment of fibromyalgia. Open Rheumatol J. 2011;5:45–50.
   PubMedGoogle Scholar
• Mendonca ME, Simis M, Grecco LC, et al. Transcranial direct current stimulation combined with aerobic exercise to optimize analgesic responses in fibromyalgia: a randomized placebo-controlled clinical trial. Front Hum Neurosci. 2016;10:68.
   PubMed Web of Science ®Google Scholar
• Picarelli H, Teixeira MJ, de Andrade DC, et al. Repetitive transcranial magnetic stimulation is efficacious as an add-on to pharmacological therapy in complex regional pain syndrome (CRPS) type I. J Pain. 2010 Nov;11(11):1203–1210.
   PubMed Web of Science ®Google Scholar
• Bradnam LV, McDonnell MN, Ridding MC. Cerebellar intermittent theta-burst stimulation and motor control training in individuals with cervical dystonia. Brain Sci. 2016 Nov 23;6(4):4.
   Web of Science ®Google Scholar
• Castelo-Branco L, Uygur Kucukseymen E, Duarte D, et al. Optimised transcranial direct current stimulation (tDCS) for fibromyalgia—targeting the endogenous pain control system: a randomised, double-blind, factorial clinical trial protocol. BMJ Open. 2019;9(10):e032710.
   PubMed Web of Science ®Google Scholar
• Portney LG, Watkins MP Foundations of clinical research: applications to practice. Pearson/Prentice Hall; 2009;3(10):193–222.
   Google Scholar
• Stagg CJ, Nitsche MA. Physiological basis of transcranial direct current stimulation. Neuroscientist. 2011 Feb;17(1):37–53.
   PubMed Web of Science ®Google Scholar
• Goh SL, Persson MSM, Stocks J, et al. Efficacy and potential determinants of exercise therapy in knee and hip osteoarthritis: A systematic review and meta-analysis. Ann Phys Rehabil Med. 2019 Sep;62(5):356–365.
   PubMed Web of Science ®Google Scholar
• Brunoni AR, Nitsche MA, Bolognini N, et al. Clinical research with transcranial direct current stimulation (tDCS): challenges and future directions. Brain Stimul. 2012 Jul;5(3):175–195.
   PubMed Web of Science ®Google Scholar
• Ambrose KR, Golightly YM. Physical exercise as non-pharmacological treatment of chronic pain: why and when. Best Pract Res Clin Rheumatol. 2015 Feb;29(1):120–130.
   PubMed Web of Science ®Google Scholar
• Busch AJ, Webber SC, Richards RS, et al. Resistance exercise training for fibromyalgia. Cochrane Database Syst Rev. 2013 Dec;20(12):Cd010884.
   Google Scholar
• Hooten WM, Qu W, Townsend CO, et al. Effects of strength vs aerobic exercise on pain severity in adults with fibromyalgia: a randomized equivalence trial. Pain. 2012 Apr;153(4):915–923.
   PubMed Web of Science ®Google Scholar
• Wang C-H, Moreau D, Yang C-T, et al. The influence of aerobic fitness on top-down and bottom-up mechanisms of interference control. Neuropsychology. 2019;33(2):245.
   PubMed Web of Science ®Google Scholar
• Hautasaari P, McLellan S, Koskio M, et al. Acute exercise modulates pain-induced response on sensorimotor cortex∼ 20 Hz oscillation. Neuroscience. 2020;429:46–55.
   PubMed Web of Science ®Google Scholar
• De Felice M, Ossipov MH. Cortical and subcortical modulation of pain. Pain Manag. 2016;6(2):111–120.
   PubMed Web of Science ®Google Scholar
• Scheef L, Jankowski J, Daamen M, et al. An fMRI study on the acute effects of exercise on pain processing in trained athletes. PAIN®. 2012;153(8):1702–1714.
   PubMed Web of Science ®Google Scholar
• Volz MS, Suarez-Contreras V, Mendonca ME, et al. Effects of sensory behavioral tasks on pain threshold and cortical excitability. PLoS One. 2013;8(1):e52968.
   PubMed Web of Science ®Google Scholar
• Bruehl S, Chung OY. Interactions between the cardiovascular and pain regulatory systems: an updated review of mechanisms and possible alterations in chronic pain. Neurosci Biobehav Rev. 2004 Jul;28(4):395–414.
   PubMed Web of Science ®Google Scholar
• Dworkin RH, Turk DC, Farrar JT, et al. Core outcome measures for chronic pain clinical trials: IMMPACT recommendations. Pain. 2005;113(1):9–19.
   PubMed Web of Science ®Google Scholar
• Menendez ME, Ring D. Factors associated with greater pain intensity. Hand Clin. 2016 Jan 02;32(1):27–31.
   PubMed Web of Science ®Google Scholar
• O’Connor PJ, Cook DB. Exercise and pain: the neurobiology, measurement, and laboratory study of pain in relation to exercise in humans. Exerc Sport Sci Rev. 1999;27:119–166.
   PubMedGoogle Scholar
• Schmitt A, Upadhyay N, Martin JA, et al. Modulation of distinct intrinsic resting state brain networks by acute exercise bouts of differing intensity. Brain Plast. 2019;5(1):39–55.
   PubMedGoogle Scholar
• Ossipov MH, Morimura K, Porreca F. Descending pain modulation and chronification of pain. Curr Opin Support Palliat Care. 2014 Jun;8(2):143–151.
   PubMed Web of Science ®Google Scholar
• Benarroch EE. Descending monoaminergic pain modulation: bidirectional control and clinical relevance. Neurology. 2008 Jul 15;71(3):217–221.
   PubMed Web of Science ®Google Scholar
• Bushnell MC, Ceko M, Low LA. Cognitive and emotional control of pain and its disruption in chronic pain. Nat Rev Neurosci. 2013;14(7):502–511.
   PubMed Web of Science ®Google Scholar
• Kosek E, Lundberg L. Segmental and plurisegmental modulation of pressure pain thresholds during static muscle contractions in healthy individuals. Eur J Pain. 2003;7(3):251–258.
   PubMed Web of Science ®Google Scholar
• Tsai C-L, Chen F-C, Pan C-Y, et al. Impact of acute aerobic exercise and cardiorespiratory fitness on visuospatial attention performance and serum BDNF levels. Psychoneuroendocrinology. 2014;41:121–131.
   PubMed Web of Science ®Google Scholar
• Du Rietz E, Barker AR, Michelini G, et al. Beneficial effects of acute high-intensity exercise on electrophysiological indices of attention processes in young adult men. Behav Brain Res. 2019;359:474–484.
   PubMed Web of Science ®Google Scholar
• Voigt J, Carpenter L, Leuchter A. Cost effectiveness analysis comparing repetitive transcranial magnetic stimulation to antidepressant medications after a first treatment failure for major depressive disorder in newly diagnosed patients - A lifetime analysis. PloS One. 2017;12(10):e0186950–e0186950.
   PubMed Web of Science ®Google Scholar
• Miyamoto GC, Lin C-WC, Cabral CMN, et al. Cost-effectiveness of exercise therapy in the treatment of non-specific neck pain and low back pain: a systematic review with meta-analysis. Br J Sports Med. 2019;53(3):172–181.
   PubMed Web of Science ®Google Scholar
• Rancic N, Mladenovic K, Ilic NV, et al. Patient-controlled intravenous morphine analgesia combined with transcranial direct current stimulation for post-thoracotomy pain: a cost-effectiveness study and a feasibility for its future implementation. Int J Environ Res Public Health. 2020;17(3):E816.
   PubMed Web of Science ®Google Scholar
• Services. USDoHaH. Physical activity and health: a report of the surgeon general. Atlanta (GA): U.S. Department of health and human services, centers for disease control and prevention, national center for chronic disease prevention and health promotion; 1996.
   Google Scholar