Managing bipolar disorder during pregnancy and the postpartum period: a critical review of current practice

References

• Merikangas KR, Jin R, He J-P, et al. Prevalence and correlates of bipolar spectrum disorder in the world mental health survey initiative. Arch Gen Psychiatry. 2011;68(3):241. .
   PubMed Web of Science ®Google Scholar
• Baldessarini RJ, Tondo L, Hennen J, et al. Treatment delays in bipolar disorders [20] (multiple letters). Am J Psychiatry. 1999;156(5):811–812. .
   PubMed Web of Science ®Google Scholar
• Freeman MP, Smith KW, Freeman SA, et al. The impact of reproductive events on the course of bipolar disorder in women. J Clin Psychiatry. 2002;63(4):284–287. .
   PubMed Web of Science ®Google Scholar
• Teatero ML, Mazmanian D, Sharma V. Effects of the menstrual cycle on bipolar disorder. Bipolar Disord. 2014;16:22–36.
   PubMed Web of Science ®Google Scholar
• Yatham LN, Kennedy SH, Parikh SV, et al. Canadian network for mood and anxiety treatments (CANMAT) and international society for bipolar disorders (ISBD) 2018 guidelines for the management of patients with bipolar disorder. Bipolar Disord. 2018;20:97–170.
   PubMed Web of Science ®Google Scholar
• Viguera AC, Tondo L, Koukopoulos AE, et al. Episodes of mood disorders in 2,252 pregnancies and postpartum periods. Am J Psychiatry. 2011;168:1179–1185.
   PubMed Web of Science ®Google Scholar
• Viguera AC. Risk of recurrence of bipolar disorder in pregnant and nonpregnant women after discontinuing lithium maintenance. Am J Psychiatry. 2000;157:179–184.
   PubMed Web of Science ®Google Scholar
• Di Florio A, Forty L, Gordon-Smith K, et al. Perinatal episodes across the mood disorder spectrum. JAMA Psychiatry. 2013;70:168–175.
   PubMed Web of Science ®Google Scholar
• Vesga-López O, Blanco C, Keyes K, et al. Psychiatric disorders in pregnant and postpartum women in the United States. Arch Gen Psychiatry. 2008;65:805–815.
   PubMed Web of Science ®Google Scholar
• Hirschfeld RMA, Williams JBW, Spitzer RL, et al. Development and validation of a screening instrument for bipolar spectrum disorder: the mood disorder questionnaire. Am J Psychiatry. 2000;157:1873–1875.
   PubMed Web of Science ®Google Scholar
• Clark CT, Sit DKY, Driscoll K, et al. Does screening with the MDQ and EPDS improve identification of bipolar disorder in an obstetrical sample? Depress. Anxiety. 2015;32:518–526.
   PubMedGoogle Scholar
• Frey BN, Simpson W, Wright L, et al. Sensitivity and specificity of the mood disorder questionnaire as a screening tool for bipolar disorder during pregnancy and the postpartum period. J Clin Psychiatry. 2012;73:1456–1461.
   PubMed Web of Science ®Google Scholar
• Masters GA, Brenckle L, Sankaran P, et al. Positive screening rates for bipolar disorder in pregnant and postpartum women and associated risk factors. Gen Hosp Psychiatry. 2019;61:53–59.
   PubMed Web of Science ®Google Scholar
• Merrill L, Mittal L, Nicoloro J, et al. Screening for bipolar disorder during pregnancy. Arch Womens Ment Health. 2015;18:579–583.
   PubMed Web of Science ®Google Scholar
• Wisner KL, Sit DKY, McShea MC, et al. Onset timing, thoughts of self-harm, and diagnoses in postpartum women with screen-positive depression findings. JAMA Psychiatry. 2013;70:490–498.
   PubMed Web of Science ®Google Scholar
• Sharma V, Khan M, Corpse C, et al. Missed bipolarity and psychiatric comorbidity in women with postpartum depression. Bipolar Disord. 2008;10:742–747.
   PubMed Web of Science ®Google Scholar
• Sharma V, Doobay M, Baczynski C. Bipolar postpartum depression : an update and recommendations. J Affect Disord. 2017;219:105–111.
   PubMed Web of Science ®Google Scholar
• Sharma V, Baczynski C. Is bipolar post-partum depression overlooked? Lancet Psychiatry. 2019;6:891–892.
   PubMed Web of Science ®Google Scholar
• Sharma V, Pope CJ. Pregnancy and bipolar disorder: a systematic review. J Clin Psychiatry. 2012;73:1447–1455.
   PubMed Web of Science ®Google Scholar
• Viguera AC, Cohen LS, Bouffard S, et al. Reproductive decisions by women with bipolar disorder after prepregnancy psychiatric consultation. Am J Psychiatry. 2002;159:2102–2104.
   PubMed Web of Science ®Google Scholar
• Salim M, Sharma V, Anderson KK. Recurrence of bipolar disorder during pregnancy: a systematic review. Arch Womens Ment Health. 2018;21:475–479.
   PubMed Web of Science ®Google Scholar
• Viguera AC, Whitfield T, Baldessarini RJ, et al. Risk of recurrence in women with bipolar disorder during pregnancy: prospective study of mood stabilizer discontinuation. Am J Psychiatry. 2007;164:1817–1824.
   PubMed Web of Science ®Google Scholar
• Newport DJ, Stowe ZN, Viguera AC, et al. Lamotrigine in bipolar disorder: efficacy during pregnancy. Bipolar Disord. 2008;10:432–436.
   PubMed Web of Science ®Google Scholar
• Gabriel M, Sharma V. Antidepressant discontinuation syndrome. CMAJ. 2017;189:E747.
   PubMed Web of Science ®Google Scholar
• Veroniki AA, Rios P, Cogo E, et al. Comparative safety of antiepileptic drugs for neurological development in children exposed during pregnancy and breast feeding: A systematic review and network meta-analysis. BMJ Open. 2017;7:1-11.
   Web of Science ®Google Scholar
• Marengo E, Martino DJ, Igoa A, et al. Unplanned pregnancies and reproductive health among women with bipolar disorder. J Affect Disord. 2015;178:201–205.
   PubMed Web of Science ®Google Scholar
• Patel N, Viguera AC, Baldessarini RJ. Mood-stabilizing anticonvulsants, spina bifida, and folate supplementation. J Clin Psychopharmacol. 2017;1:7-10.
   Google Scholar
• Williams J, Ryan D, Thomas-Peter K, et al. Best practice guidelines for mental health disorders in the perinatal period. [Internet]. 2014 [cited 2020 Jan 15]. Available from: http://bookstore.cw.bc.ca.
   Google Scholar
• National Institute for Health and Care Excellence. Antenatal and postnatal mental health: Clinical management and service guidance. 2014;1-53.
   Google Scholar
• Fornaro M, Maritan E, Ferranti R, et al. Lithium exposure during pregnancy and the postpartum period: a systematic review and meta-analysis of safety and efficacy outcomes. Am J Psychiatry. 2020;177:76–92.
   PubMed Web of Science ®Google Scholar
• Boden R, Lundgren M, Brandt L, et al. Risks of adverse pregnancy and birth outcomes in women treated or not treated with mood stabilisers for bipolar disorder: population based cohort study. BMJ. 2012;345:e7085–e7085.
   PubMed Web of Science ®Google Scholar
• Kim J-H, Choi SS, Ha K. A closer look at depression in mothers who kill their children: is it unipolar or bipolar depression? J.Clin Psychiatry. 2008;69:1625–1631.
   PubMed Web of Science ®Google Scholar
• Wesseloo R, Wierdsma AI, Van Kamp IL, et al. Lithium dosing strategies during pregnancy and the postpartum period. Br J Psychiatry. 2017;211:31–36.
   PubMed Web of Science ®Google Scholar
• Berber MJ. FINISH: remembering the discontinuation syndrome. Flu-like symptoms, insomnia, nausea, imbalance, sensory disturbances, and hyperarousal (anxiety/agitation). J Clin Psychiatry. 1998;59:255.
   PubMedGoogle Scholar
• Hudak R, Wisner KL. Diagnosis and treatment of postpartum obsessions and compulsions that involve infant harm. Am J Psychiatry. 2012;169:360–363.
   PubMed Web of Science ®Google Scholar
• Sharma V. Pharmacotherapy of postpartum obsessive–compulsive disorder: a systematic review. Expert Rev Neurother. 2018;18:925–931.
   PubMed Web of Science ®Google Scholar
• Wesseloo R, Liu X, Clark CT, et al. Risk of postpartum episodes in women with bipolar disorder after lamotrigine or lithium use during pregnancy: a population-based cohort study. J Affect Disord. 2017;218:394–397.
   PubMed Web of Science ®Google Scholar
• Clark CT, Klein AM, Perel JM, et al. Lamotrigine dosing for pregnant patients with bipolar disorder. Am J Psychiatry. 2013;170:1240–1247.
   PubMed Web of Science ®Google Scholar
• Sharma V, Sommerdyk C, Xie B, et al. Pharmacotherapy of bipolar II disorder during and after pregnancy. Curr Drug Saf. 2013;8:246–252.
   PubMedGoogle Scholar
• U.S. Food & Drug Administration. Pregnancy, lactation, and reproductive potential: labeling for human prescription drug and biological products-content and format | FDA. [Internet]. [ cited 2020 Jan 15]. Available from: https://www.fda.gov/regulatory-information/search-fda-guidance-documents/pregnancy-lactation-and-reproductive-potential-labeling-human-prescription-drug-and-biological.
   Google Scholar
• Leiknes KA, Cooke MJ, Jarosch-von Schweder L, et al. Electroconvulsive therapy during pregnancy: a systematic review of case studies. Arch Womens Ment Health. 2015;18:1–39.
   PubMed Web of Science ®Google Scholar
• Ward HB, Fromson JA, Cooper JJ, et al. Recommendations for the use of ECT in pregnancy: literature review and proposed clinical protocol.[erratum appears in arch womens ment health. 2018 Jun 23; PMID: 29934883]. Arch Womens Ment Health. 2018;21:715–722.
   PubMed Web of Science ®Google Scholar
• Cohen RB, Ferreira MS, Ferreira MJL, et al. Use of repetitive transcranial magnetic stimulation for the management of bipolar disorder during the postpartum period. Brain Stimul. 2008;1:224–226.
   PubMed Web of Science ®Google Scholar
• Xiong W, Lopez R, Cristancho P. Transcranial magnetic stimulation in the treatment of peripartum bipolar depression: A case report. Rev Bras Psiquiatr. 2018;40:344–345.
   PubMed Web of Science ®Google Scholar
• Sharma V, Singh P, Baczynski C, et al. A closer look at the nosological status of the highs (hypomanic symptoms) in the postpartum period. Arch Womens Ment Health. 2020. DOI:10.1007/s00737-020-01023-1.
   PubMed Web of Science ®Google Scholar
• Wang -Y-Y, Li X, Duan Z, et al. Screening for postpartum hypomania among Chinese women after childbirth. Psychiatry Res. 2019;282:112591.
   PubMed Web of Science ®Google Scholar
• Glover V, Liddle P, Taylor A, et al. Mild hypomania (the highs) can be a feature of the first postpartum week. Association with later depression. Br J Psychiatry. 1994;164:517–521.
   PubMed Web of Science ®Google Scholar
• Lane A, Keville R, Morris M, et al. Postnatal depression and elation among mothers and their partners: prevalence and predictors. Br J Psychiatry. 1997;171:550–555.
   PubMed Web of Science ®Google Scholar
• Hasegawa M. Mild hypomania phenomenon in Japanese puerperal women. Nurs Heal Sci. 2000;2:231–235.
   Google Scholar
• Webster J, Pritchard MA, Creedy D, et al. A simplified predictive index for the detection of women at risk for postnatal depression. Birth. 2003;30:101–108.
   PubMed Web of Science ®Google Scholar
• Heron J, Haque S, Oyebode F, et al. A longitudinal study of hypomania and depression symptoms in pregnancy and the postpartum period. Bipolar Disord. 2009;11:410–417.
   PubMed Web of Science ®Google Scholar
• Smith S, Heron J, Haque S, et al. Measuring hypomania in the postpartum: a comparison of the highs scale and the altman mania rating scale. Arch Womens Ment Health. 2009;12:323–327.
   PubMed Web of Science ®Google Scholar
• Pingo J, van den Heuvel LL, Vythylingum B, et al. Probable postpartum hypomania and depression in a South African cohort. Arch Womens Ment Health. 2017;20:427–437.
   PubMed Web of Science ®Google Scholar
• Sharma V, Xie B, Campbell MK, et al. A prospective study of diagnostic conversion of major depressive disorder to bipolar disorder in pregnancy and postpartum. Bipolar Disord. 2014;16:16–21.
   PubMed Web of Science ®Google Scholar
• Inglis AJ, Hippman CL, Carrion PB, et al. Mania and depression in the perinatal period among women with a history of major depressive disorders. Arch Womens Ment Health. 2014;17:137–143.
   PubMed Web of Science ®Google Scholar
• Azorin J-M, Angst J, Gamma A, et al. Identifying features of bipolarity in patients with first-episode postpartum depression: findings from the international BRIDGE study. J Affect Disord. 2012;136:710–715.
   PubMed Web of Science ®Google Scholar
• Munk-Olsen T, Laursen TM, Meltzer-brody S, et al. Psychiatric disorders with postpartum onset: possible early manifestations of bipolar affective disorders. Arch Gen Psychiatry. 2012;69:428–434.
   PubMed Web of Science ®Google Scholar
• Sharma V. A cautionary note on the use of antidepressants in postpartum depression. Bipolar Disord. 2006;8:411–414.
   PubMed Web of Science ®Google Scholar
• Çelik SB, Bucaktepe GE, Uludağ A, et al. Screening mixed depression and bipolarity in the postpartum period at a primary health care center. Compr Psychiatry. 2016;71:57–62.
   PubMed Web of Science ®Google Scholar
• Koukopoulos AE, Angeletti G, Sani G, et al. Perinatal mixed affective state: wherefore art thou?. Psychiatr Clin North Am. 2020;43:113–126.
   PubMed Web of Science ®Google Scholar
• American Psychiatric Association. Diagnostic and statistical manual of mental disorders. 5th ed. Washington: American Psychiatric Association; 2013.
   Google Scholar
• Sharma V, Xie B. Screening for postpartum bipolar disorder: validation of the mood disorder questionnaire. J Affect Disord. 2011;131:408–411.
   PubMed Web of Science ®Google Scholar
• Sharma V. Relationship of bipolar disorder with psychiatric comorbidity in the postpartum period — a scoping review. Arch Womens Ment Heal. 2018;21:141–147.
   PubMed Web of Science ®Google Scholar
• Sharma V, Smith A, Mazmanian D. Olanzapine in the prevention of postpartum psychosis and mood episodes in bipolar disorder. Bipolar Disord. 2006;8:400–404.
   PubMed Web of Science ®Google Scholar
• Wisner KL, Hanusa BH, Peindl KS, et al. Prevention of postpartum episodes in women with bipolar disorder. Biol Psychiatry. 2004;56:592–596.
   PubMed Web of Science ®Google Scholar
• Wesseloo R, Kamperman AM, Munk-Olsen T, et al. Risk of postpartum relapse in bipolar disorder and postpartum psychosis: a systematic review and meta-analysis. Am J Psychiatry. 2016;173:117–127.
   PubMed Web of Science ®Google Scholar
• Sharma V, Bergink V, Berk M, et al. Childbirth and prevention of bipolar disorder: an opportunity for change. Lancet Psychiatry. 2019;6:786–792.
   PubMed Web of Science ®Google Scholar
• Sharma V, Khan M, Sommerdyk C. Quetiapine in the acute treatment of bipolar postpartum depression: a chart review. J Clin Psychopharmacol. 2015;35:733–735.
   PubMed Web of Science ®Google Scholar
• Misri S, Abizadeh J, B. Eng A, et al. an open-label study of quetiapine extended-release in a sample of postpartum women with bipolar II depressive episode. Curr Psychopharmacol. 2015;4:17–26.
   Google Scholar
• Rybakowski J, Jerzy CW, Ałeck PG, et al. Recommendations of the polish psychiatric association regarding the treatment of affective disorders in women of childbearing age. Part II: bipolar disorder. Psychiatr Pol. 2019;53:263–276.
   PubMed Web of Science ®Google Scholar
• Jones I, Smith S. Puerperal psychosis: identifying and caring for women at risk. Adv Psychiatr Treat. 2009;15:411–418.
   Google Scholar
• VanderKruik R, Barreix M, Chou D, et al. The global prevalence of postpartum psychosis: a systematic review. BMC Psychiatry. 2017;17:272.
   PubMed Web of Science ®Google Scholar
• Jones I, Craddock N. Familiality of the puerperal trigger in bipolar disorder: results of a family study. Am J Psychiatry. 2001;158:913–917.
   PubMed Web of Science ®Google Scholar
• Sharma V, Mazmanian D. Sleep loss and postpartum psychosis. Bipolar Disord. 2003;5:98–105.
   PubMed Web of Science ®Google Scholar
• Lewis KJS, Foster RG, Jones IR. Is sleep disruption a trigger for postpartum psychosis?. Br J Psychiatry. 2016;208:409–411.
   PubMed Web of Science ®Google Scholar
• Blackmore ER, Jones I, Doshi M, et al. Obstetric variables associated with bipolar affective puerperal psychosis. Br J Psychiatry. 2006;188:32–36.
   PubMed Web of Science ®Google Scholar
• Sharma V, Sommerdyk C. Postpartum psychosis: what is in a name?. Aust New Zeal J Psychiatry. 2014;48:1081–1082.
   PubMed Web of Science ®Google Scholar
• Kamperman AM, Veldman-Hoek MJ, Wesseloo R, et al. Phenotypical characteristics of postpartum psychosis: A clinical cohort study. Bipolar Disord. 2017;19:450–457.
   PubMed Web of Science ®Google Scholar
• Cantwell R, Clutton-Brock T, Cooper G, et al. Saving mothers’ lives: reviewing maternal deaths to make motherhood safer: 2006-2008. BJOG An Int J Obstet Gynaecol. 2011;118:1–203.
   PubMed Web of Science ®Google Scholar
• Spinelli MG. Postpartum psychosis: detection of risk and management. Am J Psychiatry. 2009;166:405–408.
   PubMed Web of Science ®Google Scholar
• Osborne LM. Recognizing and managing postpartum psychosis: a clinical guide for obstetric providers. Obstet Gynecol Clin North Am. 2018;45:455–468.
   PubMed Web of Science ®Google Scholar
• Bergink V, Burgerhout KM, Koorengevel KM, et al. Treatment of psychosis and mania in the postpartum period. Am J Psychiatry. 2015;172:115–123.
   PubMed Web of Science ®Google Scholar
• Rönnqvist I, Brus O, Hammar Å, et al. Rehospitalization of postpartum depression and psychosis after electroconvulsive therapy. J Ect. 2019;35:264–271.
   PubMed Web of Science ®Google Scholar
• Uguz F, Sharma V. Mood stabilizers during breastfeeding: a systematic review of the recent literature. Bipolar Disord. 2016;18:325–333.
   PubMed Web of Science ®Google Scholar
• Uguz F. Second-generation antipsychotics during the lactation period a comparative systematic review on infant safety. J Clin Psychopharmacol. 2016;36:244–252.
   PubMed Web of Science ®Google Scholar
• Pacchiarotti I, León-Caballero J, Murru A, et al. Mood stabilizers and antipsychotics during breastfeeding: focus on bipolar disorder. Eur Neuropsychopharmacol. 2016;26:1562–1578.
   PubMed Web of Science ®Google Scholar
• Viguera AC, Newport DJ, Ritchie J, et al. Lithium in breast milk and nursing infants: clinical implications. Am J Psychiatry. 2007;164:342–345.
   PubMed Web of Science ®Google Scholar
• Rasmussen MLH, Strøm M, Wohlfahrt J, et al. Risk, treatment duration, and recurrence risk of postpartum affective disorder in women with no prior psychiatric history: A population-based cohort study. PLoS Med. 2017;14:e1002392.
   PubMed Web of Science ®Google Scholar
• Yatham LN, Kennedy SH, Parikh SV, et al. Canadian network for mood and anxiety treatments (CANMAT) and international society for bipolar disorders (ISBD) collaborative update of CANMAT guidelines for the management of patients with bipolar disorder: update 2013. Bipolar Disord. 2013;15:1–44.
   PubMed Web of Science ®Google Scholar
• Grof P, Robbins W, Alda M, et al. Protective effect of pregnancy in women with lithium-responsive bipolar disorder. J Affect Disord. 2000;61:31–39.
   PubMed Web of Science ®Google Scholar
• Pariente G, Leibson T, Shulman T, et al. Pregnancy outcomes following in utero exposure to lamotrigine: a systematic review and meta-analysis. CNS Drugs. 2017;31:439–450.
   Web of Science ®Google Scholar
• Coughlin CG, Blackwell KA, Bartley C, et al. Obstetric and neonatal outcomes after antipsychotic medication exposure in pregnancy. Obstet Gynecol. 2015;125:1224–1235.
   PubMed Web of Science ®Google Scholar