Speech and language therapy in primary progressive aphasia: a critical review of current practice

References

• Mesulam MM. Primary progressive aphasia and the left hemisphere language network. Dementia and Neurocognitive Disorders. 2016;15(4):93.
   PubMedGoogle Scholar
• Henry ML, Grasso SM. Assessment of individuals with primary progressive aphasia. Semin Speech Lang. 2018;39:231–241.
   PubMed Web of Science ®Google Scholar
• Taylor C, Kingma R, Croot K, et al. Speech pathology services for primary progressive aphasia: exploring an emerging area of practice. Aphasiology. 2009;23:161–174.
   Web of Science ®Google Scholar
• Volkmer A, Rogalski E, Henry M, et al. Speech and language approaches to managing primary progressive aphasia. Pract Neurol. 2020;20:154–161.
   PubMedGoogle Scholar
• Alzheimer’s Disease International. World Alzheimer report 2016: Improving healthcare for people living with dementia: coverage, quality and costs now and in the future. Alzheimer’s disease international (ADI), London, UK. Available at www.alzint.org. Accessed 2021Jan2.
   Google Scholar
• Jokel R, Metzel J, Jdr, et al. Group intervention for individuals with primary progressive aphasia and their spouses: who comes first? J Commun Disord. 2017;66:51–64.
   PubMed Web of Science ®Google Scholar
• Kortte KB, Rogalski EJ. Behavioural interventions for enhancing life participation in behavioural variant frontotemporal dementia and primary progressive aphasia. Int Rev Psychiatry. 2013;25:237–245.
   PubMed Web of Science ®Google Scholar
• Murray LL, Paek EJ. Behavioral/nonpharmacological approaches to addressing cognitive-linguistic symptoms in individuals with dementia. Perspect ASHA Spec Interest Groups. 2016;1:12–25.
   Google Scholar
• Gorno-Tempini ML, Hillis A, Weintraub S, et al. Classification of primary progressive aphasia and its variants. Neurology. 2011;76:1–9.
   Web of Science ®Google Scholar
• Seeley W, Crawford RK, Zhou J, et al. Neurodegenerative diseases target large-scale human brain networks. Neuron. 2009;62(1):45–52.
   Web of Science ®Google Scholar
• Hodges JR, Mitchell J, Dawson K. Semantic dementia: demography, familial factors and survival in a consecutive series of 100 cases. Brain. 2010;133(1):300–306.
   PubMed Web of Science ®Google Scholar
• Diehl-Schmid J, Pohl C, Perneczky R, et al. Initial symptoms, survival and causes of death in 115 patients with frontotemporal lobar degeneration. Fortschr Neurol Psychiatr [Advances in Neurology-Psychiatry]. 2007;75:708–713.
   PubMed Web of Science ®Google Scholar
• Beeson PM, King RM, Bonakdapur D, et al. Positive effects of language treatment for the logopenic variant of primary progressive aphasia. J Mol Neurosci 2011, 45: 724–736.
   PubMed Web of Science ®Google Scholar
• Croot K, Nickels L, Laurence F, et al. Impairment- and activity/participation-directed interventions in progressive language impairment: clinical and theoretical issues. Aphasiology. 2009;23:125–160.
   Web of Science ®Google Scholar
• Grossman M. Primary progressive aphasia: clinicopathological correlations. Neurology. 2010;6:88–97. Nature Reviews:.
   PubMed Web of Science ®Google Scholar
• Sebastian R, Thompson CB, Wang N-Y, et al. Patterns of decline in naming and semantic knowledge in primary progressive aphasia. Aphasiology. 2018;32:1010–1030.
   PubMed Web of Science ®Google Scholar
• Utianski RL, Botha H, Martin PR, et al. Clinical and neuroimaging characteristics of clinically unclassifiable primary progressive aphasia. Brain Lang. 2019:197. DOI: 10.1016/j.bandl.2019.104676
   Web of Science ®Google Scholar
• Marshall CR, Hardy CJ, Volkmer A, et al. Primary progressive aphasia: a clinical approach. J Neurol. 2018;265:1474–1490.
   PubMed Web of Science ®Google Scholar
• Rogalski E, Cobia D, Harrison TM, et al. Progression of language decline and cortical atrophy in subtypes of primary progressive aphasia. Neurology. 2011;76:1804–1810.
   PubMed Web of Science ®Google Scholar
• Sapolsky D, Domoto-Reilly K, Negreira A, et al. Monitoring progression of primary progressive aphasia: current approaches and future directions. Neurodegen Dis Manag. 2011;1:43–55.
   Google Scholar
• Rogalski E, Khayum B. A life participation approach to primary progressive aphasia intervention. Semin Speech Lang. 2018;39:284–296.
   PubMed Web of Science ®Google Scholar
• Kindell J, Sage K, Wilkinson R, et al. Living with semantic dementia: a case study of one family’s experience. Qual Health Res. 2014;24:401–411.
   PubMed Web of Science ®Google Scholar
• Harciarek M, Sitek EJ, Kertesz A. The patterns of progression in primary progressive aphasia-Implications for assessment and management. Aphasiology. 2014;28:964–980.
   Web of Science ®Google Scholar
• Mackenzie IRA, Neumann M, Baborie A, et al. A harmonized classification system for FTLD-TDP pathology. Acat Neuropathol. 2011;122(1):111–113.
   PubMed Web of Science ®Google Scholar
• Wilson SM, Henry ML, Besbris M, et al. Connected speech production in three variants of primary progressive aphasia. Brain. 2010;133:2069–2088.
   PubMed Web of Science ®Google Scholar
• Harris JM, Gall C, Thompson JC, et al. Classification and pathology of primary progressive aphasia. Neurology. 2013;81:1832–1839.
   PubMed Web of Science ®Google Scholar
• Harciarek M, Kertesz A. Primary progressive aphasias and their contribution to the contemporary knowledge about the brain-language relationship. Neuropsychol Rev. 2011;21:271–287.
   PubMed Web of Science ®Google Scholar
• Tsuchiya K, Ozawa E, Fukushima J, et al. Rapidly progressive aphasia and motor neurone disease: a clinical, radiological and pathological study of an autopsy case with circumscribed lobar atrophy. Acta Neuropathol. 2000;99:81–87.
   PubMed Web of Science ®Google Scholar
• Leyton CE, Britton AK, Hodges JR, et al. Distinctive pathological mechanisms involved in primary progressive aphasias. Neurobiol Aging. 2016;38:82–92.
   PubMed Web of Science ®Google Scholar
• Rohrer JD, Warren JD. Phenomenology and anatomy of abnormal behaviours in primary progressive aphasia. J Neurol Sci. 2010;293:35–38.
   PubMed Web of Science ®Google Scholar
• Pozzebon M, Douglas J, Ames D. Spousal recollections of early signs of primary progressive aphasia. Int J Lang Commun Disord. 2018;53:282–293.
   PubMed Web of Science ®Google Scholar
• Ahmed RM, Irish M, Kam J. Quantifying the eating abnormalities in frontotemporal dementia. JAMA Neurol. 2014;71:1540–1546.
   PubMed Web of Science ®Google Scholar
• Van Langenhove T, Leyton CE, Piguet O, et al. Comparing longitudinal behavior changes in the primary progressive aphasias. J Alzheimers Dis. 2016;53:1033–1042.
   PubMed Web of Science ®Google Scholar
• Rosen HJ, Allison SC, Ogar JM. Behavioral features in semantic dementia vs other forms of progressive aphasias. Neurology. 2006;67:1752–1756.
   PubMed Web of Science ®Google Scholar
• Ruggero L, Nickels L, Croot K. Quality of life in primary progressive aphasia: what do we know and what can we do next? Aphasiology. 2019;33:498–519.
   Web of Science ®Google Scholar
• Morhardt D, O’Hara M, Zachrich K, et al. Development of a psycho-educational support program for individuals with primary progressive aphasia and their care-partners. Dementia. 2017;18:1310–1327.
   PubMedGoogle Scholar
• Rutherford S. Our journey with primary progressive aphasia. Aphasiology. 2014;28:900–908.
   Web of Science ®Google Scholar
• Swaffer K. Dementia and prescribed disengagement. Dementia. 2015;14:3–6.
   PubMedGoogle Scholar
• Tagor A. Post-diagnostic support services should be included in new dementia targets. BMJ. 2013;347:15509.
   Google Scholar
• Medina J, Weintraub S. Depression in primary progressive aphasia. J Geriatr Psychiatry Neurol. 2007;20:153–160.
   PubMed Web of Science ®Google Scholar
• Mioshi E, Foxe D, Leslie F, et al. The impact of dementia severity on caregiver burden in frontotemporal dementia and Alzheimer disease. Alzheimer Dis Assoc Disord. 2013;27:68–73.
   PubMed Web of Science ®Google Scholar
• Kaiser S, Panegyres PK. The psychosocial impact of young onset dementia on spouses. Am J Alzheimers Dis Other Demen. 2007;21:398–402.
   Google Scholar
• Withall A, Draper B, Seeher K, et al. The prevalence and causes of younger onset dementia in eastern Sydney, Australia. Int Psychogeriatr. 2014;26:1955–1965.
   PubMed Web of Science ®Google Scholar
• Brooker D, LaFontaine J, Evans S, et al. Public health guidance to facilitate timely diagnosis of dementia: Alzheimer’s Cooperative Valuation in Europe recommendations. Int J Geriatr Psychiatry. 2014;29:682–693.
   PubMed Web of Science ®Google Scholar
• Phillipson L, Magee DC, Jones S, et al. Exploring dementia and stigma beliefs. Alzheimer’s Australia. Available at: www.dementia.org.au/files/20120712_US_28_Stigma_Report.pdf Accessed 15 Apr 2020
   Google Scholar
• Alzheimer’s Australia NSW. Addressing the stigma associated with dementia. Sydney, NSW: Alzheimer’s Australia NSW. Available at:www.dementia.org.au/sites/default/files/2010NSWAddressingStigmaDiscussionPaper2.pdf,June2020 Accessed 15 Apr 2020
   Google Scholar
• Research S. (2011). Dementia is everybody’s business. Canberra, Australia. Available at: www.dementia.org.au/sites/default/files/20110314_Nat_report_Pfizer-Health-Report-2011.pdf Accessed 2020May7
   Google Scholar
• Taylor C, Kingma R, Croot K & Nickels L, et al.. Speech pathology services for primary progressive aphasia: Exploring an emerging area of practice. Aphasiology 2009;23:161–174. doi:10.1080/02687030801943039
   Google Scholar
• Khayum B, Wieneke C, Rogalski E, et al. Thinking outside the stroke: treating primary progressive aphasia. Perspect Gerontol. 2012;17:37–49.
   PubMedGoogle Scholar
• Nickels L, Croot K. Understanding and living with primary progressive aphasia: current progress and challenges for the future. Aphasiology. 2014;28:885–889.
   Web of Science ®Google Scholar
• Henry ML, Grasso SM Progressive loss of language: what is PPA? Dialogue on Dementia. Available at: www.youtube.com/watch?v=8Y4ggIX8xa8 Accessed 3 Feb 2020
   Google Scholar
• Fried-Oken M. Augmentative and alternative communication treatment for persons with primary progressive aphasia. Perspect Augment Altern Commun. 2008;17:99–104.
   Google Scholar
• Rogalski EJ, Saxon M, McKenna H, et al. Communication bridge: a pilot feasibility study of Internet-based speech-language therapy for individuals with progressive aphasia. Alzheimers Dement. 2016;2:213–221.
   Google Scholar
• Gorno-Tempini ML, Dronkers NF, Rankin KP, et al. Cognition and anatomy in three variants of primary progressive aphasia. Ann Neurol. 2004;55:335–346.
   PubMed Web of Science ®Google Scholar
• Carthery-Goulart MT, Da Silveira A, Machado TH, et al. Nonpharmacological interventions for cognitive impairments following primary progressive aphasia. Dement Neuropsychol. 2013;7:122–131.
   PubMedGoogle Scholar
• Henry ML, Rising K, DeMarco AT, et al. Examining the value of lexical retrieval treatment in primary progressive aphasia: two positive cases. Brain Lang. 2013;127:145–156.
   PubMed Web of Science ®Google Scholar
• Tippett DC, Hillis AE, Tsapkini K. Treatment of primary progressive aphasia. Curr Treat Options Neurol. 2015;17:362.
   PubMed Web of Science ®Google Scholar
• Meyer AM, Tippett DC, Turner RS, et al. Long-Term maintenance of anomia treatment effects in primary progressive aphasia. Neuropsych Rehab. 2019;29(9):1439–1463.
   PubMed Web of Science ®Google Scholar
• Jokel R, Anderson ND. Quest for the best: effects of errorless and active decoding on word re-learning in semantic dementia. Neuropsychol Rehabil. 2012;22:187–214.
   PubMed Web of Science ®Google Scholar
• Jokel R, Rochon E, Anderson ND. Errorless learning of computer-generated words in a patient with semantic dementia. Neuropsychol Rehabil. 2010;20:16–41.
   PubMed Web of Science ®Google Scholar
• Coelho CA, McHugh RE, Boyle M. Semantic feature analysis as a treatment for aphasic dysnomia: a replication. Aphasiology. 2000;14:133–142.
   Web of Science ®Google Scholar
• Howard D. Cognitive neuropsychology and aphasia therapy: the case of word retrieval. In: Papathanasiou I, editor. Acquired Neurogenic Communication Disorders. London: Whurr); 2000. p. 76–99.
   Google Scholar
• Nickels L. Therapy for naming disorders: revisiting, revising, and reviewing. Aphasiology. 2000;16:935–979.
   Web of Science ®Google Scholar
• Suarez-Gonzalez A, Green Heredia C, Savage SA, et al. Restoration of conceptual knowledge in a case of semantic dementia. Neurocase. 2015;21:309–321.
   PubMed Web of Science ®Google Scholar
• Suarez-Gonzalez A, Savage SA, Caine D. Successful short-term re-learning and generalisation of concepts in semantic dementia. Neuropsychol Rehabil. 2018;28:1095–1109.
   PubMed Web of Science ®Google Scholar
• Tsapkini KK, Frangakis C, Gomez Y, et al. Augmentation of spelling therapy with transcranial direct current stimulation in primary progressive aphasia: preliminary results and challenges. Aphasiology. 2014;28:1112–1130.
   PubMed Web of Science ®Google Scholar
• Cadório I, Lousada M, Martins P, et al. Generalisation and maintenance of treatment gains in primary progressive aphasia (PPA): a systematic review. Int J Lang Commun Disord. 2017;52:543–560.
   PubMed Web of Science ®Google Scholar
• Jokel R, Graham NL, Rochon E, et al. Word retrieval therapies in primary progressive aphasia. Aphasiology. 2014;28:1038–1068.
   Web of Science ®Google Scholar
• Savage SA, Piguet O, Hodges JR. Giving words new life: generalization of word retraining outcomes in semantic dementia. J Alzheimers Dis. 2014;40:309–317.
   PubMed Web of Science ®Google Scholar
• Taylor-Rubin C, Nickels L, Croot K. Exploring the effects of verb and noun treatment on verb phrase production in primary progressive aphasia: a series of single case experimental design studies. Neuropsychol. Rehabil. 2021; DOI:10.1080/09602011.2021.1879174.
   Google Scholar
• Croot K, Raiser T, Taylor-Rubin C, et al. Lexical retrieval treatment in primary progressive aphasia: an investigation of treatment duration in a heterogeneous case series. Cortex. 2019;115:133–158.
   PubMed Web of Science ®Google Scholar
• Croot K. Treatment for lexical retrieval impairments in primary progressive aphasia: a research update with implications for clinical practice. Semin Speech Lang. 2018;39:242–256.
   PubMed Web of Science ®Google Scholar
• Taylor-Rubin C, Croot K, Nickels L. Adherence to lexical retrieval treatment in primary progressive aphasia and implications for candidacy. Aphasiology. 2019;33:1182–1201.
   Web of Science ®Google Scholar
• Henry ML, Hubbard HI, Grasso SM, et al. Retraining speech production and fluency in non-fluent/agrammatic primary progressive aphasia. Brain. 2018;141:1799–1814.
   PubMed Web of Science ®Google Scholar
• Cherney L, Halper A. Novel technology for treating individuals with aphasia and concomitant cognitive deficits. Top Stroke Rehabil. 2008;15:542–554.
   PubMed Web of Science ®Google Scholar
• Goldberg K, Haley K, Jacks A. Script training and generalization for people with aphasia. Am J Speech Lang Pathol. 2012;21:222–238.
   PubMed Web of Science ®Google Scholar
• Gibbons C, Fried-Oken M AAC clinical pathways for neurodegenerative disease. Available at: aacrerc.psu.edu/_userfiles/Gibbons_edit_OSHA_2009.pdf Accessed Aug 22 2020
   Google Scholar
• Fried-Oken M. Augmentative and alternative communication treatment for persons with primary Progressive Aphasia. Perspect Augment altern commun. 2008;17:99–104. doi:10.1080/02687030801943039
   Google Scholar
• Ho KM, Weiss SJ, Garrett KL, et al. The effect of remnant and pictographic books on the communicative interaction of individuals with global aphasia. Augment altern commun. 2005;21:218–232.
   Web of Science ®Google Scholar
• Fried-Oken M, Mooney A, Betts P. Supporting communication for patients with neurodegenerative disease. NeuroRehabilitation. 2015;37:69–87.
   PubMed Web of Science ®Google Scholar
• Sweaney E, Feel Like I I’m Fading to Grey. (Mixed media), Presented at the 11th International Conference on Frontotemporal Dementias, 4th December 2018, Sydney.
   Google Scholar
• Fried-Oken M, Rowland C, Gibbons C. Providing augmentative and alternative communication treatment to persons with progressive nonfluent aphasia. Perspect Neurophysiol Neurogenic Speech Lang Disord. 2010;20:21–25.
   Google Scholar
• Taylor-Rubin C, Croot K, Power E, et al. Communication behaviors associated with successful conversation in semantic variant primary progressive aphasia. Int Psychogeriatr. 2017;29:1619–1632.
   PubMed Web of Science ®Google Scholar
• Kindell J, Sage K, Cruice M. Supporting communication in semantic dementia: clinical consensus from expert practitioners. Qual Ageing. 2015;16:153–164.
   Google Scholar
• Volkmer A, Beeke S. How to help couples have better conversations. J Dement. 2015;23:22–24.
   Google Scholar
• Volkmer A, Spector A, Meitanis V, et al. Effects of functional communication interventions for people with primary progressive aphasia and their caregivers: a systematic review. Aging Ment Health. 2019;1–13. DOI:10.1080/13607863.2019.1617246
   Web of Science ®Google Scholar
• Beeke S, Sirman N, Beckley F, et al. Better conversations with aphasia: an e-learning resource. Available at: https://extend.ucl.ac.uk/ [ Last accessed 9 Aug 2020]
   Google Scholar
• Volkmer A, Spector A, Warren JD, et al. Better conversations with primary progressive aphasia (BCPPA): asking people with PPA and their families how speech and language therapists could support them to live well and maintain relationships. Aphasiology. 2018;32:239–240.
   Google Scholar
• Diehl J, Mayer T, Förstl H, et al. A support group for caregivers of patients with frontotemporal dementia. Dementia. 2003;2:151–161.
   Google Scholar
• Lanyon L, Rose M, Worrall L. The efficacy of outpatient and community-based aphasia group interventions: a systematic review. Int J Speech-Lang. 2013;15:359–374.
   PubMed Web of Science ®Google Scholar
• Hopper T, Cleary S, Donnelly M, et al. Serv ice delivery for older Canadians with dementia: a survey of speech-language pathologists. Can J Speech Language Pathol Audiol. 2007;31:114–126.
   Google Scholar
• Mooney A, Beale N, Fried-Oken M. Group communication treatment for individuals with PPA and their partners. Semin Speech Lang. 2018;39:257–269.
   PubMed Web of Science ®Google Scholar
• Taylor-Rubin C, Azizi L, Croot K, et al. Primary progressive aphasia education and support groups: a clinical evaluation. Am J Alzheimers Dis Other Demen. 2020;35:1–8.
   Web of Science ®Google Scholar
• Riedl L, Last D, Danek A, et al. Long-term follow-up in primary progressive aphasia: clinical course and health care utilisation. Aphasiology. 2014;28:981–992.
   Web of Science ®Google Scholar
• Davies K, Howe T. Experiences of living with primary progressive aphasia: a scoping review of qualitative studies. Am J Alzheimers Dis Other Demen. 2019. DOI:10.1177/1533317519886218
   PubMed Web of Science ®Google Scholar
• Beales A, Bates K, Cartwight J. Whitworth A Lost for words: perspectives and experiences of people with primary progressive aphasia and Alzheimer’s disease and their families of participation in a lexical retrieval intervention. Int J Speech-Lang. 2019;21:483–492.
   PubMed Web of Science ®Google Scholar
• Henry ML, Hubbard I, Grasso SM, et al. Treatment for word retrieval in semantic and logopenic variants of primary progressive aphasia: immediate and long-term outcomes. J Speech Lang Hear Res. 2019;62(8):2723–2749.
   PubMed Web of Science ®Google Scholar
• NHMRC Partnership Centre for Dealing with Cognitive and Related Functional Decline in Older People Australian Clinical Practice Guidelines and Principles of Care for People with Dementia. Available at: www.clinicalguidelines.gov.au/portal/2503/clinical-practice-guidelines-and-principles-care-people-dementia Accessed 1 Jul 2020
   Google Scholar
• Brooker D, Latham I. Person-centred dementia care, Second Edition: making Services Better with the VIPS Framework. London: Jessica Kingsley Publishers; 2016.
   Google Scholar
• O’Sullivan M, Brownsett S, Copland D. Language and language disorders: neuroscience to clinical practice. Pract Neurol. 2019;19(5):380–388.
   PubMedGoogle Scholar
• Croot K, Taylor C, Abel S, et al. Measuring gains in connected speech following treatment for word retrieval: a study with two participants with primary progressive aphasia. Aphasiology. 2015;29(11):1265–1288.
   Web of Science ®Google Scholar
• Webster J, Whitworth A. Treating verbs in aphasia: exploring the impact of therapy at the single word and sentence levels. Int J Language. 2012;47:619–636.
   Google Scholar
• Webster J, Whitworth A, Morris J. Is it time to stop “fishing”? A review of generalisation following aphasia intervention. Aphasiology. 2015;29(11):1240–1264.
   Web of Science ®Google Scholar
• Savage S, Newman C, Noad R, et al. MyWordTrainer: improving word retrieval using app-based therapy in semantic variant primary progressive aphasia. Front Hum Neurosci. 2019;13. Abstract. 10.3389/conf.fnhum.2019.01.00072
   Google Scholar
• Späth M, Digitale JH. Unterstützung in der Aphasie-und Sprechapraxietherapie am Beispiel des neolexon Therapiesystems [Digital support in aphasia and apraxia of speech therapy using the example of the Neolexon therapy system]. Neurol Und Rehabilitation. 2018;24:110–115.
   Google Scholar
• Sapolsky D, Domoto-Reilly K, Dickerson B. Use of the progressive aphasia severity scale (PASS) in monitoring speech and language status in PPA. Aphasiology. 2014;28(8–9):993–1003.
   PubMed Web of Science ®Google Scholar
• Ghany R, Tamariz L, Chen G, et al. High-touch care leads to better outcomes and lower costs in a senior population. The American Journal of Managed Care. 2018;24(9):e300–e304.
   PubMed Web of Science ®Google Scholar
• Hardy JD, Suarez-Gonzalez A, Stott J, et al. A new clinical staging system for primary progressive aphasia. Abstract. Front Hum Neurosci. 2018; 10.3389/conf.fnhum.2019.01.00052
   Google Scholar
• Giannini L, Irwin D, McMillan C, et al. Clinical marker for Alzheimer disease pathology in logopenic primary progressive aphasia. Neurology. 2017;88(24):2276–2284.
   PubMed Web of Science ®Google Scholar
• Hodges JR, Patterson K. Semantic dementia: a unique clinicopathological syndrome. Lancet Neurol. 2007;6(11):1004–1014.
   PubMed Web of Science ®Google Scholar
• Rohrer JD, Rossor MN, Warren JD. Syndromes of nonfluent primary progressive aphasia: a clinical and neurolinguistic analysis. Neurol. 2010;75(7):603–610.
   PubMed Web of Science ®Google Scholar
• Warren J, Hardy C, Fletcher P, et al. Binary reversals in primary progressive aphasia. Cortex. 2016;82:287–289.
   PubMed Web of Science ®Google Scholar
• Leyton CE, Savage S, Irish M, et al. Verbal repetition in primary progressive aphasia and Alzheimer’s disease. J Alzheimer’s Dis. 2014;41:575–585.
   PubMed Web of Science ®Google Scholar
• Butts AM, Machulda MM, Duffy JR, et al. Neuropsychological profiles differ among the three variants of primary progressive aphasia. J Int Neuropsychol Soc. 2015;21:429–435.
   PubMed Web of Science ®Google Scholar
• Piguet O, Leyton CE, Gleeson LD, et al. Memory and emotion processing performance contributes to the diagnosis of non-semantic primary. J Alzheimer’s Dis. 2015;44:541–547.
   PubMed Web of Science ®Google Scholar
• Solberger M, Neuhaus J, Ketelle R, et al. Interpersonal traits change as a function of disease type and severity in degenerative brain diseases. J Neurol Neurosurg and Ps. 2011;82(7):732–739.
   PubMed Web of Science ®Google Scholar
• Fox D, Irish M, Hu A, et al. Longitudinal cognitive and functional changes in primary progressive aphasia. Jour Neurol. 2020. 10.1007/s00415-020-10382-9
   Google Scholar
• Marczinski CA, Davidson WB, Kertesz A. A longitudinal study of behaviour in frontotemporal dementia and primary progressive aphasia. Cogn Behav Neurol. 2004;17(4):185–190.
   PubMedGoogle Scholar
• Hodges JR, Patterson K, Oxbury S, et al. Semantic dementia: progressive fluent aphasia with temporal lobe atrophy. Brain. 1992;115(6):1265–1270.
   Google Scholar
• Snowden JS, Goulding PJ, Neary D. Semantic dementia: a form of circumscribed cerebral atrophy. Behav Neurol. 1989;2(3):167e182.
   Google Scholar
• Meteyard L, Patterson K. The relation between content and structure in language production: an analysis of speech errors in semantic dementia. Brain Lang. 2009;110(3):121–134.
   PubMed Web of Science ®Google Scholar
• Bird H, Lambon Ralph MA, Patterson K, et al. The rise and fall of frequency and imageability: noun and verb production in semantic dementia. Brain Lang. 2000;73(1):17–49.
   PubMed Web of Science ®Google Scholar
• Fraser KC, Ben-David N, Hirst G, et al. Sentence segmentation of aphasic speech. In human language technologies: the 2015 annual conference of the North American chapter of the ACL. Denver: Colorado, Association for Computational Linguistics; 2015. p. 862–871.
   Google Scholar
• Ash S, Grossman M. Why study connected speech production? In: Williams RM, editor. Cognitive Neuroscience of Natural Language Use. Cambridge: Cambridge University Press; 2015. p. 29–38.
   Google Scholar
• Ash S, Moore P, Vesely L, et al. Grossman M Non-fluent speech in frontotemporal lobar degeneration. J Neurolinguistics. 2009;22(94):370–383.
   PubMedGoogle Scholar
• Josephs KA, Duffy JR, Strand EA, et al. Characterizing a neurodegenerative syndrome: primary progressive apraxia of speech. Brain. 2012;135(5):1522–1536.
   PubMed Web of Science ®Google Scholar
• Knibb JA, Woollams AM, Hodges JR, et al. Making sense of progressive non-fluent aphasia: an analysis of conversational speech. Brain. 2009;132(10):2734–2746.
   PubMedGoogle Scholar
• Irish M, Addis D, Hodges JR, et al. Considering the role of semantic memory in episodic future thinking: evidence from semantic dementia. Brain. 2012;135(7):2178–2191.
   PubMed Web of Science ®Google Scholar
• Caffarra P, Gardini S, Cappa S, et al. Degenerative jargon aphasia: unusual progression of logopenic/phonological progressive aphasia? Behav. Neurol. 2013;26:89–93.
   PubMed Web of Science ®Google Scholar
• Funyama M, Nakagawa Y, Yamaya Y, et al. Progression of logopenic variant primary progressive aphasia to apraxia and semantic memory deficits. BMC Neurol. 2013;13:158.
   PubMed Web of Science ®Google Scholar
• Boschi V, Catricala E, Consonni M, et al. Connected speech in neurodegenerative language disorders: a review. Front.Psychol. 2017;8:269.
   PubMed Web of Science ®Google Scholar