Optimal outcome measures for assessing exercise and rehabilitation approaches in chemotherapy-induced peripheral-neurotoxicity: Systematic review and consensus expert opinion

References

• Park SB, Goldstein D, Krishnan AV, et al. Chemotherapy-induced peripheral neurotoxicity: a critical analysis. CA Cancer J Clin. 2013;63(6):419–437.
   PubMed Web of Science ®Google Scholar
• Staff NP, Grisold A, Grisold W, et al. Chemotherapy-induced peripheral neuropathy: a current review. Ann Neurol. 2017;81(6):772–781.
   PubMed Web of Science ®Google Scholar
• Kanzawa-Lee GA, Larson JL, Resnicow K, et al., Exercise effects on chemotherapy-induced peripheral neuropathy: a comprehensive integrative review. Cancer Nurs. 43(3): E172–85. 2020.
   PubMedGoogle Scholar
• Kleckner IR, Park SB, Streckmann F, et al. Systematic review of exercise for prevention and management of chemotherapy-induced peripheral neuropathy. In: Lustberg MB, and Loprinzi CL, editors. Diagnosis, management and emerging strategies for chemotherapy induced neuropathy. Cham, Switzerland: Springer; 2021;183–241.
   Google Scholar
• Dorsey SG, Kleckner IR, Barton D, et al. The national cancer institute clinical trials planning meeting for prevention and treatment of chemotherapy-induced peripheral neuropathy. J Natl Cancer Inst. 2019;111(6):531–537.
   PubMedGoogle Scholar
• Tanay MAL, Armes J, Moss-Morris R, et al. A systematic review of behavioural and exercise interventions for the prevention and management of chemotherapy-induced peripheral neuropathy symptoms. J Cancer Surviv. 2021. DOI:https://doi.org/10.1007/s11764-021-00997-w.
   Google Scholar
• Jordan B, Margulies A, Cardoso F, et al., Systemic anticancer therapy-induced peripheral and central neurotoxicity: ESMO-EONS-EANO Clinical Practice Guidelines for diagnosis, prevention, treatment and follow-up. Ann Oncol. 31(10): 1306–1319. 2020.
   PubMed Web of Science ®Google Scholar
• Loprinzi CL, Lacchetti C, Bleeker J, et al., Prevention and management of chemotherapy-induced peripheral neuropathy in survivors of adult cancers: ASCO guideline update. J Clin Oncol. 38(28): 3325–3348. 2020.
   PubMed Web of Science ®Google Scholar
• Gewandter JS, Brell J, Cavaletti G, et al., Trial designs for chemotherapy-induced peripheral neuropathy prevention: ACTTION recommendations. Neurology. 91(9): 403–413. 2018.
   PubMed Web of Science ®Google Scholar
• Alberti P, Rossi E, Cornblath DR, et al. Physician-assessed and patient-reported outcome measures in chemotherapy-induced sensory peripheral neurotoxicity: two sides of the same coin. Ann Oncol. 2014;25(1):257–264.
   PubMed Web of Science ®Google Scholar
• Page MJ, McKenzie JE, Bossuyt PM, et al. The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. BMJ. 2021;372:n71.
   PubMed Web of Science ®Google Scholar
• Argyriou AA, Cavaletti G, Park SB. The toxic neuropathy consortium of the peripheral nerve society. J Peripher Nerv Syst. 2019;24 Suppl 2:S4–5.
   PubMed Web of Science ®Google Scholar
• Boers M, Beaton DE, Shea BJ, et al. OMERACT filter 2.1: elaboration of the conceptual framework for outcome measurement in health intervention studies. J Rheumatol. 2019;46(8):1021–1027.
   PubMed Web of Science ®Google Scholar
• Bland KA, Kirkham AA, Bovard J, et al. Effect of exercise on taxane chemotherapy-induced peripheral neuropathy in women with breast cancer: a randomized controlled trial. Clin Breast Cancer. 2019;19(6):411–422.
   PubMed Web of Science ®Google Scholar
• Chen SC, Huang HP, Huang WS, et al. Non-randomized preliminary study of an education and elastic-band resistance exercise program on severity of neuropathy, physical function, muscle strength and endurance & quality of life in colorectal cancer patients experiencing oxaliplatin-induced peripheral neuropathy. Eur J Oncol Nurs. 2020;49:101834.
   PubMed Web of Science ®Google Scholar
• Hatlevoll I, Oldervoll LM, Wibe A, et al. Physical exercise during adjuvant chemotherapy for colorectal cancer-a non-randomized feasibility study. Support Care Cancer. 2021;29(6):2993–3008.
   PubMed Web of Science ®Google Scholar
• Kneis S, Wehrle A, Müller J, et al. It’s never too late - balance and endurance training improves functional performance, quality of life, and alleviates neuropathic symptoms in cancer survivors suffering from chemotherapy-induced peripheral neuropathy: results of a randomized controlled trial. BMC Cancer. 2019;19(1):414.
   PubMedGoogle Scholar
• McCrary JM, Goldstein D, Sandler CX, et al. Exercise-based rehabilitation for cancer survivors with chemotherapy-induced peripheral neuropathy. Support Care Cancer. 2019;27(10):3849–3857.
   PubMed Web of Science ®Google Scholar
• Müller J, Weiler M, Schneeweiss A, et al., Preventive effect of sensorimotor exercise and resistance training on chemotherapy-induced peripheral neuropathy: a randomised-controlled trial. Br J Cancer. 125(7): 955–965. 2021.
   PubMed Web of Science ®Google Scholar
• Vollmers PL, Mundhenke C, Maass N, et al. Evaluation of the effects of sensorimotor exercise on physical and psychological parameters in breast cancer patients undergoing neurotoxic chemotherapy. J Cancer Res Clin Oncol. 2018;144(9):1785–1792.
   PubMed Web of Science ®Google Scholar
• Bao T, Zhi I, Baser R, et al. Yoga for chemotherapy-induced peripheral neuropathy and fall risk: a randomized controlled trial. 2020 JNCI Cancer Spectr;4(6):kaa048.
   Web of Science ®Google Scholar
• Clark PG, Cortese-Jimenez G, Cohen E. Effects of reiki, yoga, or meditation on the physical and psychological symptoms of chemotherapy-induced peripheral neuropathy: a randomized pilot study. J Evid Based Complement Alternat Med. 2012;17(3):161–171.
   Google Scholar
• Galantino ML, Tiger R, Brooks J, et al. Impact of somatic yoga and meditation on fall risk, function, and quality of life for chemotherapy-induced peripheral neuropathy syndrome in cancer survivors. Integr Cancer Ther. 2019;18:1534735419850627.
   Web of Science ®Google Scholar
• Gui Q, Li D, Zhuge Y, et al. Efficacy of exercise rehabilitation program in relieving oxaliplatin induced peripheral neurotoxicity. Asian Pac J Cancer Prev. 2021;22(3):705–709.
   PubMedGoogle Scholar
• Schönsteiner SS, Bauder Mißbach H, Benner A, et al. A randomized exploratory phase 2 study in patients with chemotherapy-related peripheral neuropathy evaluating whole-body vibration training as adjunct to an integrated program including massage, passive mobilization and physical exercises. Exp Hematol Oncol. 2017;6(1):5.
   PubMedGoogle Scholar
• Streckmann F, Lehmann HC, Balke M, et al. Sensorimotor training and whole-body vibration training have the potential to reduce motor and sensory symptoms of chemotherapy-induced peripheral neuropathy-a randomized controlled pilot trial. Support Care Cancer. 2019;27(7):2471–2478.
   PubMed Web of Science ®Google Scholar
• Zimmer P, Trebing S, Timmers-Trebing U, et al. Eight-week, multimodal exercise counteracts a progress of chemotherapy-induced peripheral neuropathy and improves balance and strength in metastasized colorectal cancer patients: a randomized controlled trial. Support Care Cancer. 2018;26(2):615–624.
   PubMed Web of Science ®Google Scholar
• Şimşek Ny, Demir A. Cold application and exercise on development of peripheral neuropathy during taxane chemotherapy in breast cancer patients: a randomized controlled trial. Asia Pac J Oncol Nurs. 2021;8(3):255–266.
   PubMed Web of Science ®Google Scholar
• Kleckner IR, Kamen C, Gewandter JS, et al., Effects of exercise during chemotherapy on chemotherapy-induced peripheral neuropathy: a multicenter, randomized controlled trial. Support Care Cancer. 26(4): 1019–1028. 2018.
   PubMed Web of Science ®Google Scholar
• Dhawan S, Andrews R, Kumar L, et al. A randomized controlled trial to assess the effectiveness of muscle strengthening and balancing exercises on chemotherapy-induced peripheral neuropathic pain and quality of life among cancer patients. Cancer Nurs. 2020;43(4):269–280.
   PubMed Web of Science ®Google Scholar
• Andersen Hammond E, Pitz M, Steinfeld K, et al. An exploratory randomized trial of physical therapy for the treatment of chemotherapy-induced peripheral neuropathy. Neurorehabil Neural Repair. 2020;34(3):235–246.
   PubMed Web of Science ®Google Scholar
• Wonders KY. The Effect of Supervised Exercise Training on Symptoms of Chemotherapy-Induced Peripheral Neuropathy. Int J Phys Med Rehabil. 2014;2(4):4.
   Google Scholar
• Bahar-Ozdemir Y, Akyuz G, Kalkandelen M, et al. The effect of therapeutic exercises on balance, quality of life, and pain in patients who were receiving neurotoxic chemotherapy. Am J Phys Med Rehabil. 2020;99(4):291–299.
   PubMed Web of Science ®Google Scholar
• Fernandes J, Kumar S. Effect of lower limb closed kinematic chain exercises on balance in patients with chemotherapy-induced peripheral neuropathy: a pilot study. Int J Rehabil Res. 2016;39(4):368–371.
   PubMed Web of Science ®Google Scholar
• Frigeni B, Piatti M, Lanzani F, et al. Chemotherapy-induced peripheral neurotoxicity can be misdiagnosed by the National Cancer Institute Common Toxicity scale. J Peripher Nerv Syst. 2011;16(3):228–236.
   PubMed Web of Science ®Google Scholar
• Tofthagen C, Visovsky C, Beckstead J, et al. Results of a strength and balance training pilot study for colorectal cancer survivors with peripheral neuropathy caused by Oxaliplatin. Rehabil Oncol. 2014;32(4):38–44.
   Google Scholar
• Griffith KA, Dorsey SG, Renn CL, et al. Correspondence between neurophysiological and clinical measurements of chemotherapy-induced peripheral neuropathy: secondary analysis of data from the CI-PeriNomS study. J Peripher Nerv Syst. 2014;19(2):127–135.
   PubMed Web of Science ®Google Scholar
• Streckmann F, Kneis S, Leifert JA, et al. Exercise program improves therapy-related side-effects and quality of life in lymphoma patients undergoing therapy. Ann Oncol. 2014;25(2):493–499.
   PubMed Web of Science ®Google Scholar
• Stuecher K, Bolling C, Vogt L, et al. Exercise improves functional capacity and lean body mass in patients with gastrointestinal cancer during chemotherapy: a single-blind RCT. Support Care Cancer. 2019;27(6):2159–2169.
   PubMed Web of Science ®Google Scholar
• Argyriou AA, Park SB, Islam B, et al., Neurophysiological, nerve imaging and other techniques to assess chemotherapy-induced peripheral neurotoxicity in the clinical and research settings. J Neurol Neurosurg Psychiatry. 90(12): 1361–1369. 2019.
   PubMed Web of Science ®Google Scholar
• Alberti P, Rossi E, Argyriou AA, et al. Risk stratification of oxaliplatin induced peripheral neurotoxicity applying electrophysiological testing of dorsal sural nerve. Support Care Cancer. 2018;26(9):3143–3151.
   PubMed Web of Science ®Google Scholar
• Velasco R, Bruna J, Briani C, et al. Early predictors of oxaliplatin-induced cumulative neuropathy in colorectal cancer patients. J Neurol Neurosurg Psychiatry. 2014;85(4):392–398.
   PubMed Web of Science ®Google Scholar
• Henke CC, Cabri J, Fricke L, et al. Strength and endurance training in the treatment of lung cancer patients in stages IIIA/IIIB/IV. Support Care Cancer. 2014;22(1):95–101.
   PubMed Web of Science ®Google Scholar
• Schwenk M, Grewal GS, Holloway D, et al. Interactive sensor-based balance training in older cancer patients with chemotherapy-induced peripheral neuropathy: a randomized controlled trial. Gerontology. 2016;62(5):553–563.
   PubMed Web of Science ®Google Scholar
• Crossnohere NL, Brundage M, Calvert MJ, et al. International guidance on the selection of patient-reported outcome measures in clinical trials: a review. Qual Life Res. 2021;30(1):21–40.
   PubMed Web of Science ®Google Scholar
• Timmins HC, Li T, Kiernan MC, et al. quantification of small fiber neuropathy in chemotherapy-treated patients. J Pain. 2020;21:44–58.
   PubMed Web of Science ®Google Scholar
• Cavaletti G, Frigeni B, Lanzani F, et al., The total neuropathy score as an assessment tool for grading the course of chemotherapy-induced peripheral neurotoxicity: comparison with the National cancer institute-common toxicity scale. J Peripher Nerv Syst. 12(3): 210–215. 2007.
   PubMed Web of Science ®Google Scholar
• Argyriou AA, Bruna J, Anastopoulou GG, et al. Assessing risk factors of falls in cancer patients with chemotherapy-induced peripheral neurotoxicity. Support Care Cancer. 2020;28(4):1991–1995.
   PubMed Web of Science ®Google Scholar
• Martinez ARM, Martins MP, Martins CR Jr., et al. Sensory ataxia rating scale: development and validation of a functional scale for patients with sensory neuronopathies. J Peripher Nerv Syst. 2019;24(3):242–246.
   PubMed Web of Science ®Google Scholar
• Patrizio E, Calvani R, Marzetti E, et al. Physical functional assessment in older adults. J Frailty Aging. 2021;10(2):141–149.
   PubMed Web of Science ®Google Scholar
• Agarwala P, Salzman SH. Six-minute walk test: clinical role, technique, coding, and reimbursement. Chest. 2020;157(3):603–611.
   PubMed Web of Science ®Google Scholar
• Aversa Z, Costelli P, Muscaritoli M. Cancer-induced muscle wasting: latest findings in prevention and treatment. Ther Adv Med Oncol. 2017;9(5):369–382.
   PubMed Web of Science ®Google Scholar
• Park SH. Tools for assessing fall risk in the elderly: a systematic review and meta-analysis. Aging Clin Exp Res. 2018;30(1):1–16.
   PubMed Web of Science ®Google Scholar
• Dixon CJ, Knight T, Binns E, et al. Clinical measures of balance in people with type two diabetes: a systematic literature review. Gait Posture. 2017;58:325–332.
   PubMed Web of Science ®Google Scholar
• Sherman KJ. The trials and tribulations of selecting comparison groups in randomized trials of nonpharmacological complementary and integrative health interventions. J Altern Complement Med. 2020;26(6):449–455.
   PubMed Web of Science ®Google Scholar