143
Views
0
CrossRef citations to date
0
Altmetric
Meta-analysis

Superior treatment efficacy of neuromodulation rehabilitation for upper limb recovery after stroke: a meta-analysis

, , , , &
Pages 875-888 | Received 28 Jul 2022, Accepted 14 Oct 2022, Published online: 22 Oct 2022

References

  • Collaborators GBDN, Nichols E, Alam T. Global, regional, and national burden of neurological disorders, 1990-2016: a systematic analysis for the global burden of disease study 2016. Lancet Neurol. 2019;18(5):459–480.
  • Kelly-Hayes M, Beiser A, Kase CS, et al. The influence of gender and age on disability following ischemic stroke: the Framingham study. J Stroke Cerebrovasc Dis. 2003;12(3):119–126.
  • Wade DT, Langton-Hewer R, Wood VA, et al. The hemiplegic arm after stroke: measurement and recovery. J Neurol Neurosurg Psychiatry. 1983;46(6):521–524.
  • Stinear CM, Lang CE, Zeiler S, et al. Advances and challenges in stroke rehabilitation. Lancet Neurol. 2020;19(4):348–360.
  • Horsley S, Lannin NA, Hayward KS, et al. Additional early active repetitive motor training did not prevent contracture in adults receiving task-specific upper limb training after stroke: a randomised trial. J Physiother. 2019;65(2):88–94.
  • Harris JE, Eng JJ. Strength training improves upper-limb function in individuals with stroke: a meta-analysis. Stroke. 2010;41(1):136–140.
  • Mehrholz J, Pohl M, Platz T, et al. Electromechanical and robot-assisted arm training for improving activities of daily living, arm function, and arm muscle strength after stroke. Cochrane Database Syst Rev. 2018;9:CD006876.
  • Lannin NA, Ada L, English C, et al., Effect of additional rehabilitation after botulinum toxin-a on upper limb activity in chronic stroke: the inTENSE trial. Stroke. 2020. 51(2): 556–562.
  • Lefebvre S, Dricot L, Laloux P, et al. Neural substrates underlying stimulation-enhanced motor skill learning after stroke. Brain. 2015;138(1):149–163.
  • Allman C, Amadi U, Winkler AM, et al. Ipsilesional anodal tDCS enhances the functional benefits of rehabilitation in patients after stroke. Sci Transl Med. 2016;8(330):330re1.
  • Derakhshanfar M, Raji P, Bagheri H, et al. Sensory interventions on motor function, activities of daily living, and spasticity of the upper limb in people with stroke: a randomized clinical trial. J Hand Ther. 2021;34(4):515–520.
  • Stinear CM, Barber PA, Coxon JP, et al. Priming the motor system enhances the effects of upper limb therapy in chronic stroke. Brain. 2008;131(5):1381–1390.
  • Guyatt GH, Oxman AD, Vist GE, et al. GRADE: an emerging consensus on rating quality of evidence and strength of recommendations. BMJ. 2008;336(7650):924–926.
  • Fu J, Zeng M, Shen F, et al. Effects of action observation therapy on upper extremity function, daily activities and motion evoked potential in cerebral infarction patients. Medicine (Baltimore). 2017;96(42):e8080.
  • Liu KP, Balderi K, Leung TL, et al. A randomized controlled trial of self-regulated modified constraint-induced movement therapy in sub-acute stroke patients. Eur J Neurol. 2016;23(8):1351–1360.
  • Prange GB, Kottink AI, Buurke JH, et al. The effect of arm support combined with rehabilitation games on upper-extremity function in subacute stroke: a randomized controlled trial. Neurorehabil Neural Repair. 2015;29(2):174–182.
  • Yelnik AP, Quintaine V, Andriantsifanetra C, et al. AMOBES (Active Mobility Very Early After Stroke): a randomized controlled trial. Stroke. 2017;48(2):400–405.
  • Niama Natta DD, Lejeune T, Detrembleur C, et al. Effectiveness of a self-rehabilitation program to improve upper-extremity function after stroke in developing countries: a randomized controlled trial. Ann Phys Rehabil Med. 2021;64(1):101413.
  • Wu X, Guarino P, Lo AC, et al. Long-term effectiveness of intensive therapy in chronic stroke. Neurorehabil Neural Repair. 2016;30(6):583–590.
  • Jiang W, Wang S, Wu Q, et al. Effects of self-assisted shoulder elevation of the affected side combined with balance training on associated reactions of upper limb and walking function in chronic stroke patients: a randomized controlled trial. Med Sci Monit. 2021;27:e928549.
  • Rodgers H, Bosomworth H, Krebs HI, et al. Robot-assisted training compared with an enhanced upper limb therapy programme and with usual care for upper limb functional limitation after stroke: the RATULS three-group RCT. Health Technol Assess. 2020;24:1–232.
  • Wu Z, Xu J, Yue C, et al. Collaborative care model based telerehabilitation exercise training program for acute stroke patients in China: a randomized controlled trial. J Stroke Cerebrovasc Dis. 2020;29(12):105328.
  • Meng G, Meng X, Tan Y, et al. Short-term efficacy of hand-arm bimanual intensive training on upper arm function in acute stroke patients: a randomized controlled trial. Front Neurol. 2017;8(726).
  • Yadav RK, Sharma R, Borah D, et al. Efficacy of modified constraint induced movement therapy in the treatment of hemiparetic upper limb in stroke patients: a randomized controlled trial. J Clin Diagn Res. 2016;10(11):YC01–YC5.
  • Dido YM, Dulo OA. Dynamic of upper limb sensorimotor recovery assessed on the Fugl-Meyer scale in post-stroke patients with neglect syndrome receiving combined physical therapy and ergotherapy. Wiad Lek. 2021;74(4):849–855.
  • Cramer SC, Dodakian L, Le V, et al. Efficacy of home-based telerehabilitation vs in-clinic therapy for adults after stroke: a randomized clinical trial. JAMA Neurol. 2019;76(9):1079–1087.
  • Frolov AA, Mokienko O, Lyukmanov R, et al. Post-stroke rehabilitation training with a motor-imagery-based brain-computer interface (bci)-controlled hand exoskeleton: a randomized controlled multicenter trial. Front Neurosci. 2017;11:400.
  • Harvey RL, Edwards D, Dunning K, et al. Randomized sham-controlled trial of navigated repetitive transcranial magnetic stimulation for motor recovery in stroke. Stroke. 2018;49(9):2138–2146.
  • Kiper P, Szczudlik A, Agostini M, et al. Virtual reality for upper limb rehabilitation in subacute and chronic stroke: a randomized controlled trial. Arch Phys Med Rehabil. 2018;99(5):834–42 e4.
  • Li G, Yuan W, Liu G, et al. Effects of radial extracorporeal shockwave therapy on spasticity of upper-limb agonist/antagonist muscles in patients affected by stroke: a randomized, single-blind clinical trial. Age Ageing. 2020;49(2):246–252.
  • Aprile I, Germanotta M, Cruciani A, et al. Upper limb robotic rehabilitation after stroke: a multicenter, randomized clinical trial. J Neurol Phys Ther. 2020;44(1):3–14.
  • Long Y, Ouyang RG, Zhang JQ. Effects of virtual reality training on occupational performance and self-efficacy of patients with stroke: a randomized controlled trial. J Neuroeng Rehabil. 2020;17(1):150.
  • Ogun MN, Kurul R, Yasar MF, et al. Effect of leap motion-based 3D immersive virtual reality usage on upper extremity function in ischemic stroke patients. Arq Neuropsiquiatr. 2019;77(10):681–688.
  • Kim WS, Kwon BS, Seo HG, et al. Low-frequency repetitive transcranial magnetic stimulation over contralesional motor cortex for motor recovery in subacute ischemic stroke: a randomized sham-controlled trial. Neurorehabil Neural Repair. 2020;34(9):856–867.
  • Sharma H, Vishnu VY, Kumar N, et al. Efficacy of low-frequency repetitive transcranial magnetic stimulation in ischemic stroke: a double-blind randomized controlled trial. Arch Rehabil Res Clin Transl. 2020;2(1):100039.
  • Raglio A, Panigazzi M, Colombo R, et al. Hand rehabilitation with sonification techniques in the subacute stage of stroke. Sci Rep. 2021;11(1):7237.
  • Kong KH, Loh YJ, Thia E, et al. Efficacy of a virtual reality commercial gaming device in upper limb recovery after stroke: a randomized, controlled study. Top Stroke Rehabil. 2016;23(5):333–340.
  • Laffont I, Froger J, Jourdan C, et al. Rehabilitation of the upper arm early after stroke: video games versus conventional rehabilitation. A randomized controlled trial. Ann Phys Rehabil Med. 2020;63(3):173–180.
  • Wolf SL, Sahu K, Bay RC, et al. The HAAPI (Home Arm Assistance Progression Initiative) trial: a novel robotics delivery approach in stroke rehabilitation. Neurorehabil Neural Repair. 2015;29(10):958–968.
  • Chen J, Sun D, Zhang S, et al. Effects of home-based telerehabilitation in patients with stroke: a randomized controlled trial. Neurology. 2020;95(17):e2318–e30.
  • Takebayashi T, Takahashi K, Domen K, et al. Impact of initial flexor synergy pattern scores on improving upper extremity function in stroke patients treated with adjunct robotic rehabilitation: a randomized clinical trial. Top Stroke Rehabil. 2020;27(7):516–524.
  • Guo J, Qian S, Wang Y, et al. Clinical study of combined mirror and extracorporeal shock wave therapy on upper limb spasticity in poststroke patients. Int J Rehabil Res. 2019;42(1):31–35.
  • Ain QU, Khan S, Ilyas S, et al. Additional effects of xbox kinect training on upper limb function in chronic stroke patients: a randomized control trial. Healthcare (Basel). 2021;9(3):242.
  • Johnson L, Bird ML, Muthalib M, et al. An innovative stroke interactive virtual therapy (strive) online platform for community-dwelling stroke survivors: a randomized controlled trial. Arch Phys Med Rehabil. 2020;101(7):1131–1137.
  • Mao H, Li Y, Tang L, et al. Effects of mirror neuron system-based training on rehabilitation of stroke patients. Brain Behav. 2020;10(8):e01729.
  • Ding L, Wang X, Guo X, et al. Camera-based mirror visual feedback: potential to improve motor preparation in stroke patients. IEEE Trans Neural Syst Rehabil Eng. 2018;26(9):1897–1905.
  • Lokk J, Salman Roghani R, Delbari A. Effect of methylphenidate and/or levodopa coupled with physiotherapy on functional and motor recovery after stroke–a randomized, double-blind, placebo-controlled trial. Acta Neurol Scand. 2011;123(4):266–273.
  • Goldstein LB, Lennihan L, Rabadi MJ, et al. Effect of dextroamphetamine on poststroke motor recovery: a randomized clinical trial. JAMA Neurol. 2018;75(12):1494–1501.
  • Chang WH, Lee J, Shin YI, et al. Cerebrolysin combined with rehabilitation enhances motor recovery and prevents neural network degeneration in ischemic stroke patients with severe motor deficits. J Pers Med. 2021;11(6):545.
  • Yu M, Sun ZJ, Li LT, et al. The beneficial effects of the herbal medicine Di-huang-yin-zi (dhyz) on patients with ischemic stroke: a randomized, placebo controlled clinical study. Complement Ther Med. 2015;23(4):591–597.
  • Nasb M, Li Z, A SAY, et al. Comparison of the effects of modified constraint-induced movement therapy and intensive conventional therapy with a botulinum-a toxin injection on upper limb motor function recovery in patients with stroke. Libyan J Med. 2019;14(1):1609304.
  • Sun Z, Xu Q, Gao G, et al. Clinical observation in edaravone treatment for acute cerebral infarction. Niger J Clin Pract. 2019;22(10):1324–1327.
  • Asadollahi M, Ramezani M, Khanmoradi Z, et al. The efficacy comparison of citalopram, fluoxetine, and placebo on motor recovery after ischemic stroke: a double-blind placebo-controlled randomized controlled trial. Clin Rehabil. 2018;32(8):1069–1075.
  • Carrico C, Westgate PM, Salmon Powell E, et al. Nerve stimulation enhances task-oriented training for moderate-to-severe hemiparesis 3-12 months after stroke: a randomized trial. Am J Phys Med Rehabil. 2018;97(11):808–815.
  • Kwakkel G, Winters C, van Wegen EE, et al. Effects of unilateral upper limb training in two distinct prognostic groups early after stroke: the explicit-stroke randomized clinical trial. Neurorehabil Neural Repair. 2016;30(9):804–816.
  • Wang HQ, Hou M, Li H, et al. Effects of acupuncture treatment on motor function in patients with subacute hemorrhagic stroke: a randomized controlled study. Complement Ther Med. 2020;49:102296.
  • Zhou M, Li F, Lu W, et al. Efficiency of neuromuscular electrical stimulation and transcutaneous nerve stimulation on hemiplegic shoulder pain: a randomized controlled trial. Arch Phys Med Rehabil. 2018;99(9):1730–1739.
  • Wei YX, Zhao X, Zhang BC. Synergistic effect of moxibustion and rehabilitation training in functional recovery of post-stroke spastic hemiplegia. Complement Ther Med. 2016;26:55–60.
  • Long H, Wang H, Zhao C, et al. Effects of combining high- and low-frequency repetitive transcranial magnetic stimulation on upper limb hemiparesis in the early phase of stroke. Restor Neurol Neurosci. 2018;36(1):21–30.
  • Gong Y, Long XM, Xu Y, et al. Effects of repetitive transcranial magnetic stimulation combined with transcranial direct current stimulation on motor function and cortex excitability in subacute stroke patients: a randomized controlled trial. Clin Rehabil. 2021;35(5):718–727.
  • Lou G, Fu C, Du Q, et al. TheraSling therapy (tst) combined with neuromuscular facilitation technique on hemiplegic gait in patients with stroke. Med Sci Monit. 2019;25:4766–4772.
  • Khan F, Rathore C, Kate M, et al. The comparative efficacy of theta burst stimulation or functional electrical stimulation when combined with physical therapy after stroke: a randomized controlled trial. Clin Rehabil. 2019;33(4):693–703.
  • Levy RM, Harvey RL, Kissela BM, et al. Epidural electrical stimulation for stroke rehabilitation: results of the prospective, multicenter, randomized, single-blinded everest trial. Neurorehabil Neural Repair. 2016;30(2):107–119.
  • Dawson J, Liu CY, Francisco GE, et al. Vagus nerve stimulation paired with rehabilitation for upper limb motor function after ischaemic stroke (VNS-REHAB): a randomised, blinded, pivotal, device trial. Lancet. 2021;397(10284):1545–1553.
  • Chen L, Fang J, Ma R, et al. Additional effects of acupuncture on early comprehensive rehabilitation in patients with mild to moderate acute ischemic stroke: a multicenter randomized controlled trial. BMC Complement Altern Med. 2016;16(1):226.
  • Luo L, Yu Z, Yang Y, et al. Clinical observation on Wang Juyi’s applied channel theory in treating stroke-sequel patients. J Tradit Chin Med. 2018;38(4):593–600.
  • Xiong J, Zhang Z, Ma Y, et al. The effect of combined scalp acupuncture and cognitive training in patients with stroke on cognitive and motor functions. NeuroRehabilitation. 2020;46(1):75–82.
  • Zheng J, Wu Q, Wang L, et al. A clinical study on acupuncture in combination with routine rehabilitation therapy for early pain recovery of post-stroke shoulder-hand syndrome. Exp Ther Med. 2018;15(2):2049–2053.
  • Duval S, Tweedie R. Trim and fill: a simple funnel-plot-based method of testing and adjusting for publication bias in meta-analysis. Biometrics. 2000;56(2):455–463.
  • Koganemaru S, Mima T, Thabit MN, et al. Recovery of upper-limb function due to enhanced use-dependent plasticity in chronic stroke patients. Brain. 2010;133(11):3373–3384.
  • Barker RN, Brauer SG, Carson RG. Training of reaching in stroke survivors with severe and chronic upper limb paresis using a novel nonrobotic device: a randomized clinical trial. Stroke. 2008;39(6):1800–1807.
  • Joy MT, Carmichael ST. Encouraging an excitable brain state: mechanisms of brain repair in stroke. Nat Rev Neurosci. 2021;22(1):38–53.
  • Font MA, Arboix A, Krupinski J. Angiogenesis, neurogenesis and neuroplasticity in ischemic stroke. Curr Cardiol Rev. 2010;6(3):238–244.
  • Takahashi K, Domen K, Sakamoto T, et al. Efficacy of upper extremity robotic therapy in subacute poststroke hemiplegia: an exploratory randomized trial. Stroke. 2016;47(5):1385–1388.
  • Mekbib DB, Zhao Z, Wang J, et al. Proactive motor functional recovery following immersive virtual reality-based limb mirroring therapy in patients with subacute stroke. Neurotherapeutics. 2020;17(4):1919–1930.
  • Wagner TH, Lo AC, Peduzzi P, et al. An economic analysis of robot-assisted therapy for long-term upper-limb impairment after stroke. Stroke. 2011;42(9):2630–2632.
  • Collaboration AT, Hackett ML, Almeida OP. Safety and efficacy of fluoxetine on functional outcome after acute stroke (AFFINITY): a randomised, double-blind, placebo-controlled trial. Lancet Neurol. 2020;19(8):651–660.
  • Shaw LC, Price CI, van Wijck FM, et al. Botulinum Toxin for the Upper Limb after Stroke (BoTULS) trial: effect on impairment, activity limitation, and pain. Stroke. 2011;42(5):1371–1379.
  • Hussain N, Alt Murphy M, Sunnerhagen KS. Upper limb kinematics in stroke and healthy controls using target-to-target task in virtual reality. Front Neurol. 2018;9:300.
  • Lee HH, Kim DY, Sohn MK, et al., Revisiting the proportional recovery model in view of the ceiling effect of Fugl-Meyer assessment. Stroke. 2021. 52(10): 3167–3175.
  • Hernandez ED, Galeano CP, Barbosa NE, et al., Intra- and inter-rater reliability of Fugl-Meyer assessment of upper extremity in stroke. J Rehabil Med. 2019. 51(9): 652–659.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.