Advanced search
Publication Cover
Expert Opinion on Drug Safety Volume 19, 2020 - Issue 9
Submit an article Journal homepage
259
Views
2
CrossRef citations to date
0
Altmetric
Original research

The effects of atorvastatin and rosuvastatin on exercise tolerance in patients with coronary heart disease

Dan Liua Department of Cardiology, Peking University Third Hospital, NHC Key Laboratory of Cardiovascular Molecular Biology and Regulatory Peptides, Key Laboratory of Molecular Cardiovascular Science, Ministry of Education, Beijing, ChinaView further author information
,
Tao Shena Department of Cardiology, Peking University Third Hospital, NHC Key Laboratory of Cardiovascular Molecular Biology and Regulatory Peptides, Key Laboratory of Molecular Cardiovascular Science, Ministry of Education, Beijing, ChinaView further author information
,
Chuan Rena Department of Cardiology, Peking University Third Hospital, NHC Key Laboratory of Cardiovascular Molecular Biology and Regulatory Peptides, Key Laboratory of Molecular Cardiovascular Science, Ministry of Education, Beijing, ChinaView further author information
,
Shunlin Xua Department of Cardiology, Peking University Third Hospital, NHC Key Laboratory of Cardiovascular Molecular Biology and Regulatory Peptides, Key Laboratory of Molecular Cardiovascular Science, Ministry of Education, Beijing, ChinaView further author information
,
Lequn Zhoua Department of Cardiology, Peking University Third Hospital, NHC Key Laboratory of Cardiovascular Molecular Biology and Regulatory Peptides, Key Laboratory of Molecular Cardiovascular Science, Ministry of Education, Beijing, ChinaView further author information
,
Jin Baia Department of Cardiology, Peking University Third Hospital, NHC Key Laboratory of Cardiovascular Molecular Biology and Regulatory Peptides, Key Laboratory of Molecular Cardiovascular Science, Ministry of Education, Beijing, ChinaView further author information
,
Nan Lib Research Center of Clinical Epidemiology, Peking University Third Hospital, Beijing, ChinaView further author information
,
Wei Zhaoa Department of Cardiology, Peking University Third Hospital, NHC Key Laboratory of Cardiovascular Molecular Biology and Regulatory Peptides, Key Laboratory of Molecular Cardiovascular Science, Ministry of Education, Beijing, China;c Physical Examination Center, Peking University Third Hospital, Beijing, ChinaCorrespondence[email protected]
View further author information
&
Wei Gaoa Department of Cardiology, Peking University Third Hospital, NHC Key Laboratory of Cardiovascular Molecular Biology and Regulatory Peptides, Key Laboratory of Molecular Cardiovascular Science, Ministry of Education, Beijing, ChinaView further author information
 show all
Pages 1203-1208 | Received 19 Dec 2019, Accepted 19 Jun 2020, Published online: 02 Jul 2020

References

  • Vanhees L, Rauchet B, Piepolial M, et al. Importance of characteristics and modalities of physical activity and exercise in the management of cardiovascular health in individuals with cardiovascular disease (Part III). Eur J Prev Cardiol. 2012;19(6):1333–1356.
  • Simic I, Reiner Z. Adverse effects of statins - myths and reality. Curr Pharm Des. 2015;21(9):1220–1226.
  • Mezzani A. Cardiopulmonary exercise testing: basics of methodology and measurements. Ann Am Thorac Soc. 2017;14(Supplement_1):S3–S11. .
  • Guazzi M, Arena R, Halle M, et al. 2016 focused update: clinical recommendations for cardiopulmonary exercise testing data assessment in specific patient populations. Eur Heart J. 2018;39(14):1144–1161..
  • Parker BA, Capizzi JA, Grimaldi AS, et al., The effect of statins on skeletal muscle function. Circulation. 2013;127(1): 96–103.
  • Qureshi WT, Keteyian SJ, Brawner CA, et al. Impact of statin use on cardiorespiratory fitness in multi-racial men and women: the henry ford exercise testing (FIT) project. Int J Cardiol. 2015;197:76–77.
  • Robinson JG, Smith B, Maheshwari N, et al. Pleiotropic effects of statins: benefit beyond cholesterol reduction? A meta-regression analysis. J Am Coll Cardiol. 2005;46(10):1855–1862..
  • Reiner Z. Statins in the primary prevention of cardiovascular disease. Nat Rev Cardiol. 2013;10(8):453–464.
  • Taylor BA, Thompson PD. Statin-associated muscle disease: advances in diagnosis and management. Neurotherapeutics. 2018;15(4):1006–1017.
  • Thompson PD, Panza G, Zaleski A, et al., Statin-associated side effects. J Am Coll Cardiol. 2016;67(20): 2395–2410.
  • Ganga HV, Slim HB, Thompson PD. A systematic review of statin-induced muscle problems in clinical trials. Am Heart J. 2014;168(1):6–15.
  • Gupta A, Thompson D, Whitehouse A, et al., Adverse events associated with unblinded, but not with blinded, statin therapy in the Anglo-Scandinavian Cardiac Outcomes Trial-Lipid-Lowering Arm (ASCOT-LLA): a randomised double-blind placebo-controlled trial and its non-randomised non-blind extension phase. Lancet. 2017;389(10088): 2473–2481.
  • Pedro-Botet J, Climent E, Benaiges D. Muscle and statins: from toxicity to the nocebo effect. Expert Opin on Drug Saf. 2019;18(7):573–579.
  • Collaborative Group. SEARCH, Link E, Parish S, et al. SLCO1B1 variants and statin-induced myopathy–a genomewide study. N Engl J Med. 2008;359(8):789–799.
  • Knauer MJ, Urquhart BL, Meyer Zu Schwabedissen HE, et al. Human skeletal muscle drug transporters determine local exposure and toxicity of statins. Circ Res. 2010;106(2):297–306..
  • Bellosta S, Corsini A. Statin drug interactions and related adverse reactions. Expert Opin Drug Saf. 2012;11(6):933–946.
  • Mammen AL, Amato AA. Statin myopathy: a review of recent progress. Curr Opin Rheumatol. 2010;22(6):644–650.
  • Xing YY, Liu J, Hao YC, et al. Prehospital statin use and low-density lipoprotein cholesterol levels at admission in acute coronary syndrome patients with history of myocardial infarction or revascularization: findings from the improving care for cardiovascular disease in China (CCC) Project. Am Heart J. 2019;212:120–128.
  • Joint Committee for Developing Chinese guidelines on Prevention and Treatment of Dyslipidemia in Adults. Guidelines for prevention and treatment of dyslipidemia in Chinese adults (revised 2016). Chin Circul J. 2016;31:937–953.
  • Yamamoto S, Hotta K, Ota E. Effects of resistance training on muscle strength, exercise capacity, and mobility in middle-aged and elderly patients with coronary artery disease: A meta-analysis. J Cardiol. 2016;68(2):125–134.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.