Trends and concerns of potentially inappropriate medication use in patients with cardiovascular diseases

References

• Brinker LM, Konerman MC, Navid P, et al. Complex and Potentially Harmful Medication Patterns in Heart Failure with Preserved Ejection Fraction. S0002-9343(20)30700-2 Am J Med. 2021;1343:374–382.
   PubMed Web of Science ®Google Scholar
• Roux B, Sirois C, Simard M, et al. One-year persistence of potentially inappropriate medication use in older adults: a population-based study. Br J Clin Pharmacol. 2020;86(6):1062–1080.
   PubMed Web of Science ®Google Scholar
• Beers MH, Ouslander JG, Rollingher I, et al. Explicit criteria for determining inappropriate medication use in nursing home residents. UCLA Division of Geriatric Medicine. Arch Intern Med. 1991;151(9):1825–1832.
   PubMedGoogle Scholar
• Bouterige A, Mercier J, Makaroff Z, et al. Medication management of hypertension and heart failure in older patients: what happens to therapeutic changes after hospitalization? Ann Cardiol Angeiol (Paris). 2020;69(2):60–66.
   PubMedGoogle Scholar
• Dornquast C, Dombrowski M, Zabel M, et al. Potential drug-drug interactions in patients with indication for prophylactic implantation of a cardioverter defibrillator: a cross-sectional analysis. BMC Health Serv Res. 2020;20(1):271.
   PubMed Web of Science ®Google Scholar
• Aguiar JP, Brito AM, Martins AP, et al. Alves da Costa F. Potentially inappropriate medications with risk of cardiovascular adverse events in the elderly: a systematic review of tools addressing inappropriate prescribing. J Clin Pharm Ther. 2019;44(3):349–360.
   PubMed Web of Science ®Google Scholar
• Aguiar JP, Heitor Costa L, Alves Da CF, et al. Identification of potentially inappropriate medications with risk of major adverse cardiac and cerebrovascular events among elderly patients in ambulatory setting and long-term care facilities. Clin Interv Aging. 2019;14:535–547.
   PubMed Web of Science ®Google Scholar
• Muhlack DC, Hoppe LK, Weberpals J, et al. Association of Potentially Inappropriate Medication at Older Age With Cardiovascular Events and Overall Mortality: a Systematic Review and Meta-Analysis of Cohort Studies. J Am Med Dir Assoc. 2017 Mar 1;18(3):211–220.
   PubMed Web of Science ®Google Scholar
• Storms H, Marquet K, Aertgeerts B, et al. Prevalence of inappropriate medication use in residential long-term care facilities for the elderly: a systematic review. Eur J Gen Pract. 2017;23(1):69–77.
   PubMed Web of Science ®Google Scholar
• Redston MR, Hilmer SN, McLachlan AJ, et al. Prevalence of Potentially Inappropriate Medication Use in Older Inpatients with and without Cognitive Impairment: a Systematic Review. J Alzheimers Dis. 2018;61(4):1639–1652.
   PubMed Web of Science ®Google Scholar
• Nothelle SK, Sharma R, Oakes AH, et al. Determinants of Potentially Inappropriate Medication Use in Long-Term and Acute Care Settings: a Systematic Review. J Am Med Dir Assoc. 2017;18(9):806.e1–806.e17.
   PubMed Web of Science ®Google Scholar
• Lohman MC, Cotton BP, Zagaria AB, Bao Y, Greenberg RL, Fortuna KL, Bruce ML. Hospitalization Risk and. Potentially Inappropriate Medications among Medicare Home Health Nursing Patients. J Gen Intern Med. 2017;32(12): 1301–1308.
   PubMed Web of Science ®Google Scholar
• Lopes LM, Figueiredo TP, Costa SC, et al. Use of potentially inappropriate medications by the elderly at home. Cien Saude Colet. 2016;21(11):3429–3438.
   PubMed Web of Science ®Google Scholar
• Ivanova I, Elseviers M, Wettermark B, et al. Electronic assessment of cardiovascular potentially inappropriate medications in an administrative population database. Basic Clin Pharmacol Toxicol. 2019;124(1):62–73.
   PubMed Web of Science ®Google Scholar
• Alosaimy S, Vaidya A, Day K, et al. Effect of a Pharmacist-Driven Medication Management Intervention Among Older Adults in an Inpatient Setting. Drugs Aging. 2019;36(4):371–378.
   PubMed Web of Science ®Google Scholar
• Price M, Davies I, Rusk R, et al. STOPP Guidelines in Primary Care Through Electronic Medical Record Decision Support: randomized Control Trial Highlighting the Importance of Data Quality. JMIR Med Inform. 2017;5(2):e15.
   PubMed Web of Science ®Google Scholar
• Lou MF. [Current State of Appropriate Medication Use in Older Adults and Future Prospects]. Chinese Hu Li Za Zhi. 2019;664:4–6.
   PubMedGoogle Scholar
• Topinková E, Baeyens JP, Michel JP, et al. Evidence-based strategies for the optimization of pharmacotherapy in older people. Drugs Aging. 2012;29(6):477–494.
   PubMed Web of Science ®Google Scholar
• Alagiakrishnan K, Mah D, Padwal R. Classic challenges and emerging approaches to medication therapy in older adults. Discov Med. 2018;26(143):137–146.
   PubMed Web of Science ®Google Scholar
• Kondo N, Nakamura F, Yamazaki S, et al. Prescription of potentially inappropriate medications to elderly hemodialysis patients: prevalence and predictors. Nephrol Dial Transplant. 2015;30(3):498–505.
   PubMed Web of Science ®Google Scholar
• Fialová D, Laffon B, Marinković V, et al. EUROAGEISM H2020 project and WG1b group “Healthy clinical strategies for healthy aging” of the EU COST Action IS 1402. Medication use in older patients and age-blind approach: narrative literature review (insufficient evidence on the efficacy and safety of drugs in older age, frequent use of PIMs and polypharmacy, and underuse of highly beneficial nonpharmacological strategies). Eur J Clin Pharmacol. 2019;75(4):451–466.
   PubMed Web of Science ®Google Scholar
• Grina D, Briedis V. The use of potentially inappropriate medications among the Lithuanian elderly according to Beers and EU(7)-PIM list - a nationwide cross-sectional study on reimbursement claims data. J Clin Pharm Ther. 2017 2;42:195–200. Epub 2017 Feb 2. PMID: 28155237.
   PubMed Web of Science ®Google Scholar
• Beers MH. Explicit criteria for determining potentially inappropriate medication use by the elderly. Arch Intern Med. 1997;157(14):1531–1536.
   PubMed Web of Science ®Google Scholar
• Stolar MH. Drug use review: operational definitions. Am J Hosp Pharm. 1978;35(1):76–78.
   PubMedGoogle Scholar
• Fastbom J, Johnell K. National indicators for quality of drug therapy in older persons: the Swedish experience from the first 10 years. Drugs Aging. 2015;32(3):189–199.
   PubMed Web of Science ®Google Scholar
• Fick DM, Cooper JW, Wade WE, et al. Updating the Beers criteria for potentially inappropriate medication use in older adults: results of a US consensus panel of experts. Arch Intern Med. 2003 Dec 8-22;163(22):2716–2724. 2004;164(3):298.
   PubMed Web of Science ®Google Scholar
• By the American Geriatrics Society. Beers Criteria Update Expert Panel. American Geriatrics Society 2015 Updated Beers Criteria for Potentially Inappropriate Medication Use in Older Adults. J Am Geriatr Soc. 2015;63(11):2227–2246.
   PubMed Web of Science ®Google Scholar
• McLeod PJ, Huang AR, Tamblyn RM, et al. Defining inappropriate practices in prescribing for elderly people: a national consensus panel. CMAJ. 1997;156(3):385–391.
   PubMed Web of Science ®Google Scholar
• Roughead EE, Anderson B, Gilbert AL. Potentially inappropriate prescribing among Australian veterans and war widows/widowers. Intern Med J. 2007;37(6):402–405.
   PubMed Web of Science ®Google Scholar
• Jungo KT, Mantelli S, Rozsnyai Z, et al. General practitioners’ deprescribing decisions in older adults with polypharmacy: a case vignette study in 31 countries. BMC Geriatr. 2021;21(1):19.
   PubMed Web of Science ®Google Scholar
• Dа S, Danilina KS, Golovina ОV. [The frequency of potentially inappropriate medication use according to the Beers’ criteria in elderly people at the therapy departments of a multidisciplinary hospital]. Russian Ter Arkh. 2015;871:27–30.
   Web of Science ®Google Scholar
• Renom-Guiteras A, Meyer G, Thürmann PA. The EU(7)-PIM list: a list of potentially inappropriate medications for older people consented by experts from seven European countries. Eur J Clin Pharmacol. 2015;71(7):861–875.
   PubMed Web of Science ®Google Scholar
• Kimura T, Ogura F, Kukita Y, et al. Efficacy of pharmacists’ assessment and intervention based on Screening Tool for Older Persons’ Appropriate Prescriptions for Japanese compared with Screening Tool of Older Persons’ potentially inappropriate Prescriptions criteria version 2 in older patients with cardiovascular disease. 2020 Jan;20(1):91 Geriatr Gerontol Int. 2019;1911:1101–1107.
   PubMed Web of Science ®Google Scholar
• Denholm R, Morris R, Payne R. Polypharmacy patterns in the last year of life in patients with dementia. Eur J Clin Pharmacol. 2019;75(11):1583–1591.
   PubMed Web of Science ®Google Scholar
• Oliveira HSB, Michels AC, Nahime M, et al. Risk factors associated with potential cardiovascular and cerebrovascular adverse events in elderly individuals assisted at secondary level. Rev Assoc Med Bras (1992). 2020;66(8):1087–1092.
   PubMed Web of Science ®Google Scholar
• Varallo FR, Capucho HC, Planeta CS, et al. Safety assessment of potentially inappropriate medications use in older people and the factors associated with hospital admission. J Pharm Pharm Sci. 2011;14(2):283–290.
   PubMed Web of Science ®Google Scholar
• Al-Omar HA, Al-Sultan MS, Abu-Auda HS. Prescribing of potentially inappropriate medications among the elderly population in an ambulatory care setting in a Saudi military hospital: trend and cost. Geriatr Gerontol Int. 2013;13(3):616–621.
   PubMed Web of Science ®Google Scholar
• Harugeri A, Joseph J, Parthasarathi G, et al. Potentially inappropriate medication use in elderly patients: a study of prevalence and predictors in two teaching hospitals. J Postgrad Med. 2010;56(3):186–191.
   PubMed Web of Science ®Google Scholar
• Puchon E, Goboova M, Vano I, et al. Medication-related factors associated with proton pump inhibitor prescription beyond official guidelines in older adults. Eur Geriatr Med. 2020;11(6):1051–1061.
   PubMed Web of Science ®Google Scholar
• Piccoliori G, Mahlknecht A, Sandri M, et al. Epidemiology and associated factors of polypharmacy in older patients in primary care: a northern Italian cross-sectional study. BMC Geriatr. 2021;21(1):197.
   PubMed Web of Science ®Google Scholar
• Lavan AH, Gallagher P, Parsons C, et al. STOPPFrail (Screening Tool of Older Persons Prescriptions in Frail adults with limited life expectancy): consensus validation. Age Ageing. 2017;46(4):600–607.
   PubMed Web of Science ®Google Scholar
• Ryan C, O’Mahony D, Dó O, et al. A comparison of the application of STOPP/START to patients’ drug lists with and without clinical information. Int J Clin Pharm. 2013;35(2):230–235.
   PubMed Web of Science ®Google Scholar
• Al-Dahshan A, Prevalence KV. Predictors of Potentially Inappropriate Medication Prescription Among Older Adults: a Cross-Sectional Study in the State of Qatar. Drugs Real World Outcomes. 2021;8(1):95–103.
   PubMedGoogle Scholar
• Mori AL, Carvalho RC, Aguiar PM, et al. Potentially inappropriate prescribing and associated factors in elderly patients at hospital discharge in Brazil: a cross-sectional study. Int J Clin Pharm. 2017;39(2):386–393.
   PubMed Web of Science ®Google Scholar
• Ö K, Arık G, Kızılarslanoglu MC, et al. Potentially inappropriate prescribing according to the STOPP/START criteria for older adults. Aging Clin Exp Res. 2016;28(4):761–768.
   PubMed Web of Science ®Google Scholar
• Fahrni Essebag V, AlTurki A, Proietti R, et al. Concomitant anti-platelet therapy in warfarin-treated patients undergoing cardiac rhythm device implantation: a secondary analysis of the BRUISE CONTROL trial. Int J Cardiol. 2019;288:87–93.
   PubMed Web of Science ®Google Scholar
• Bo M, Gibello M, Brunetti E, et al. Prevalence and predictors of inappropriate prescribing according to the Screening Tool of Older People’s Prescriptions and Screening Tool to Alert to Right Treatment version 2 criteria in older patients discharged from geriatric and internal medicine wards: a prospective observational multicenter study. Geriatr Gerontol Int. 2019;19(1):5–11.
   PubMed Web of Science ®Google Scholar
• Lavan AH, O’Mahony D, Gallagher P. STOPPFrail (Screening Tool of Older Persons’ Prescriptions in Frail adults with a limited life expectancy) criteria: application to a representative population awaiting long-term nursing care. Eur J Clin Pharmacol. 2019;75(5):723–731.
   PubMed Web of Science ®Google Scholar
• Gavilán Moral E, Morales Suárez-Varela MT, Hoyos Esteban JA, et al. Polimedicación y prescripción de fármacos inadecuados en pacientes ancianos inmovilizados que viven en la comunidad [Inappropriate multiple medication and prescribing of drugs immobile elderly patients living in the community]. Spanish Aten Primaria. 2006;389:476–480.
   PubMedGoogle Scholar
• Lavan AH, O’Mahony D, O’Mahony D, et al. Potentially inappropriate medication (PIM) use and severe drug interactions (SDIs) in older adults with cancer. J Geriatr Oncol. 2021. S1879-4068(21)00045-X. DOI:https://doi.org/10.1016/j.jgo.2021.02.021
   Google Scholar
• Liu CL, Peng LN, Chen YT, et al. Potentially inappropriate prescribing (IP) for elderly medical inpatients in Taiwan: a hospital-based study. Arch Gerontol Geriatr. 2012;55(1):148–151.
   PubMed Web of Science ®Google Scholar
• Mancia G, De Backer G, Dominiczak A, et al. 2007 Guidelines for the Management of Arterial Hypertension. J Hypertens. 2007;25(6):1105–1187.
   PubMed Web of Science ®Google Scholar
• Lochner S, Kirch W, Schindler C. Managing hypertension among nursing-home residents and community-dwelling elderly in Germany: a comparative pharmacoepidemiological study. Eur J Clin Pharmacol. 2012;68(5):867–875.
   PubMed Web of Science ®Google Scholar
• Buda V, Prelipcean A, Andor M, et al. Potentially Inappropriate Prescriptions in Ambulatory Elderly Patients Living in Rural Areas of Romania Using STOPP/START (Version 2) Criteria. Clin Interv Aging. 2020;15:407–417.
   PubMed Web of Science ®Google Scholar
• Mielke N, Huscher D, Douros A, et al. Self-reported medication in community-dwelling older adults in Germany: results from the Berlin Initiative Study. BMC Geriatr. 2020;20(1):22.
   PubMed Web of Science ®Google Scholar
• Fahrni ML, Azmy MT, Usir E, et al. Inappropriate prescribing defined by STOPP and START criteria and its association with adverse drug events among hospitalized older patients: a multicentre, prospective study. PLoS One. 2019;14(7):e0219898.
   PubMed Web of Science ®Google Scholar
• Halvorsen KH, Selbaek G, Ruths S. Trends in potentially inappropriate medication prescribing to nursing home patients: comparison of three cross-sectional studies. Pharmacoepidemiol Drug Saf. 2017;26(2):192–200.
   PubMed Web of Science ®Google Scholar
• Butool I, Nazir S, Afridi M, et al. Evaluation and assessment of prescribing patterns in elderly patients using two explicit criteria based screening tools: (The PRISCUS list and STOPP/START criteria). Pak J Med Sci. 2018;34(6):1357–1362.
   PubMed Web of Science ®Google Scholar
• Motallebzadeh N, Jayaprakash G, Mohammadi E. Evaluation of Rationality of Geriatric Patients’ Prescription Based On Beers Criteria in a Tertiary Care Hospital in India. Open Access Maced J Med Sci. 2019;7(6):987–991.
   PubMedGoogle Scholar
• Sönnerstam E, Sjölander M, Gustafsson M. An evaluation of the prevalence of potentially inappropriate medications in older people with cognitive impairment living in Northern Sweden using the EU(7)-PIM list. Eur J Clin Pharmacol. 2017;73(6):735–742.
   PubMed Web of Science ®Google Scholar
• Wang Y, Singh S, Bajorek B. Old age, high risk medication, polypharmacy: a ‘trilogy’ of risks in older patients with atrial fibrillation. Pharm Pract (Granada). 2016;14(2):706.
   PubMedGoogle Scholar
• Momin TG, Pandya RN, Rana DA, et al. Use of potentially inappropriate medications in hospitalized elderly at a teaching hospital: a comparison between Beers 2003 and 2012 criteria. Indian J Pharmacol. 2013;45(6):603–607.
   PubMed Web of Science ®Google Scholar
• Onda M, Imai H, Takada Y, et al. Identification and prevalence of adverse drug events caused by potentially inappropriate medication in homebound elderly patients: a retrospective study using a nationwide survey in Japan. BMJ Open. 2015;5(8):e007581.
   PubMed Web of Science ®Google Scholar
• Montastruc F, Duguet C, Rousseau V, et al. Potentially inappropriate medications and adverse drug reactions in the elderly: a study in a PharmacoVigilance database. Eur J Clin Pharmacol. 2014;70(9):1123–1127.
   PubMed Web of Science ®Google Scholar
• Price SD, Holman CD, Sanfilippo FM, et al. Association between potentially inappropriate medications from the Beers criteria and the risk of unplanned hospitalization in elderly patients. Ann Pharmacother. 2014;48(1):6–16.
   PubMed Web of Science ®Google Scholar
• Keith SW, Maio V, Dudash K, et al. A physician-focused intervention to reduce potentially inappropriate medication prescribing in older people: a 3-year, Italian, prospective, proof-of-concept study. Drugs Aging. 2013;30(2):119–127.
   PubMed Web of Science ®Google Scholar
• Zahwe M, Skouri H, Rachidi S, et al. Potentially inappropriate medications in elderly patients with heart failure: beers Criteria-based study. Int J Pharm Pract. 2020;28(6):652–659.
   PubMed Web of Science ®Google Scholar
• Wang F, Ma Z, Liu M, et al. Potentially inappropriate medications at admission and discharge in older adults: a comparison of the Beers 2019 and 2015 criteria. Int J Clin Pharmacol Ther. 2020;58(6):299–309.
   PubMed Web of Science ®Google Scholar
• Alturki A, Alaama T, Alomran Y, et al. Potentially inappropriate medications in older patients based on Beers criteria: a cross-sectional study of a family medicine practice in. Arabia S. BJGP Open. 2020. 4(1): bjgpopen20X101009. DOI:https://doi.org/10.3399/bjgpopen20X101009
   Google Scholar
• Schnegg D, Senn N, Bugnon O, et al. Drug Prescription in Older Swiss Men and Women Followed in Family Medicine. Drugs Real World Outcomes. 2020;7(1):87–95.
   PubMedGoogle Scholar
• Huang CH, Umegaki H, Watanabe Y, et al. Potentially inappropriate medications according to STOPP-J criteria and risks of hospitalization and mortality in elderly patients receiving home-based medical services. PLoS One. 2019;14(2):e0211947.
   PubMed Web of Science ®Google Scholar
• Sato I, Yamamoto Y, Kato G, et al. Potentially Inappropriate Medication Prescribing and Risk of Unplanned Hospitalization among the Elderly: a Self-Matched, Case-Crossover Study. Drug Saf. 2018;41(10):959–968.
   PubMed Web of Science ®Google Scholar
• Jastaniah NA, Almaqati AS, Alsuraihi AK, et al. Inappropriate Prescribing in Elderly Inpatients at a University Hospital in Saudi Arabia. Drugs Real World Outcomes. 2018;5(4):211–216.
   PubMedGoogle Scholar
• Montastruc F, Gardette V, Cantet C, Piau A, Lapeyre-Mestre M, Vellas B, Montastruc JL, Andrieu S; REAL.FR Group. Potentially inappropriate medication use among patients with Alzheimer disease in the REAL.FR cohort: be aware of atropinic and benzodiazepine drugs! Eur J Clin Pharmacol. 2013;69(8): 1589–1597.
   PubMed Web of Science ®Google Scholar
• Bongue B, Laroche ML, Gutton S, et al. Potentially inappropriate drug prescription in the elderly in France: a population-based study from the French National Insurance Healthcare system. Eur J Clin Pharmacol. 2011;67(12):1291–1299.
   PubMed Web of Science ®Google Scholar
• Maggiore RJ, Dale W, Gross CP, et al., Cancer and Aging Research Group. Polypharmacy and potentially inappropriate medication use in older adults with cancer undergoing chemotherapy: effect on chemotherapy-related toxicity and hospitalization during treatment. J Am Geriatr Soc. 2014;62(8):1505–1512.
   PubMed Web of Science ®Google Scholar
• Schubert I, Küpper-Nybelen J, Ihle P, et al. Prescribing potentially inappropriate medication (PIM) in Germany’s elderly as indicated by the PRISCUS list. An analysis based on regional claims data. Pharmacoepidemiol Drug Saf. 2013;22(7):719–727.
   PubMed Web of Science ®Google Scholar
• Woelfel JA, Patel RA, Walberg MP, et al. Use of potentially inappropriate medications in an ambulatory Medicare population. Consult Pharm. 2011;26(12):913–919.
   PubMedGoogle Scholar
• Masuda E, Ozsvath K, Vossler J, et al. appropriate use criteria for chronic lower extremity venous disease of the American Venous Forum, the Society for Vascular Surgery, the American Vein and Lymphatic Society, and the Society of Interventional Radiology. J Vasc Surg Venous Lymphat Disord. 2020;8(4):505–525.e4.
   PubMedGoogle Scholar
• Teressa G, Manjur J, Ciuffo M, et al. Validation of Appropriate Use Criteria for Coronary Computed Tomographic Angiography for Chest Pain Evaluation in a Tertiary Care Emergency Room. J Thorac Imaging. 2020;35(3):193–197.
   PubMed Web of Science ®Google Scholar
• Petersen SE, Friebel R, Ferrari V, et al. and Potential Drivers of Non-invasive Cardiovascular Imaging Use in the United States of America and England. Front Cardiovasc Med. 2021;7:617771.
   PubMed Web of Science ®Google Scholar
• Pontone G, Di Cesare E, Castelletti S, et al. Appropriate use criteria for cardiovascular magnetic resonance imaging (CMR): SIC-SIRM position paper part 1 (ischemic and congenital heart diseases, cardio-oncology, cardiac masses and heart transplant). Radiol Med. 2021;126(3):365–379.
   PubMed Web of Science ®Google Scholar
• Roifman I, Paterson DI, Jimenez-Juan L, et al. The State of Cardiovascular Magnetic Resonance Imaging in Canada: results from the CanSCMR Pan-Canadian Survey. Can J Cardiol. 2018;34(3):333–336.
   PubMed Web of Science ®Google Scholar
• Erthal F, Premaratne M, Yam Y, et al. Appropriate Use Criteria for Cardiac Computed Tomography: does Computed Tomography Have Incremental Value in All Appropriate Use Criteria Categories? J Thorac Imaging. 2018;33(2):132–137.
   PubMed Web of Science ®Google Scholar
• Cho MS, Roh JH, Park H, Cho SC, Kang DY, Lee PH, Ahn JM, Koo HJ, Yang DH, Kang JW, Park SJ, Patel MR, Park DW. Practice Pattern, Diagnostic Yield, and. Long-Term Prognostic Impact of Coronary Computed Tomographic Angiography. J Am Heart Assoc. 2020;9(18): e016620.
   PubMed Web of Science ®Google Scholar
• Kauppi JM, Airaksinen KEJ, Saha J, et al. Adherence to risk-assessment protocols to guide computed tomography pulmonary angiography in patients with suspected pulmonary embolism. Eur Heart J Qual Care Clin Outcomes. 2021 Mar 16. qcab020. DOI:https://doi.org/10.1093/ehjqcco/qcab020
   Google Scholar
• Charles A, Ingolf C. Meta-analysis on outcome-worsening comorbidities of COVID-19 and related potential drug-drug interactions. Pharmacol Res. 2020;105250. DOI:https://doi.org/10.1016/j.phrs.2020.105250
   Google Scholar
• Frattini S, Maccagni G, Italia L, et al. Coronavirus disease 2019 and cardiovascular implications. J Cardiovasc Med (Hagerstown). 2020;21(10):725–732.
   PubMed Web of Science ®Google Scholar
• Mai F, Del Pinto R, Ferri CCOVID-19. and cardiovascular diseases. J Cardiol. 2020;76(5):453–458.
   PubMed Web of Science ®Google Scholar
• Phelps M, Christensen DM, Gerds T, et al. Cardiovascular comorbidities as predictors for severe COVID-19 infection or death. Eur Heart J Qual Care Clin Outcomes. 2020 Oct 27. qcaa081. DOI:https://doi.org/10.1093/ehjqcco/qcaa081
   Google Scholar
• Quagliariello V, Bonelli A, Caronna A, et al. SARS-CoV-2 Infection and Cardioncology: from Cardiometabolic Risk Factors to Outcomes in Cancer Patients. Cancers (Basel). 2020;12(11):E3316.
   PubMed Web of Science ®Google Scholar
• Huang B, Xu C, Liu H, et al. Outcomes of Acute Myocardial Infarction Before and During the Coronavirus Disease 2019 Pandemic. J Cardiovasc Pharmacol. 2020;76(5):540–548.
   PubMed Web of Science ®Google Scholar
• Festa M, Sansone C, Brunet C, et al. Cardiovascular Active Peptides of Marine Origin with ACE Inhibitory Activities: potential Role as Anti-Hypertensive Drugs and in Prevention of SARS-CoV-2 Infection. Int J Mol Sci. 2020;21(21):8364.
   Web of Science ®Google Scholar
• Gubitosa JC, Kakar P, Gerula C, et al. Marked Sinus Bradycardia Associated With Remdesivir in COVID-19: a Case and Literature Review. JACC Case Rep. 2020;2(14):2260–2264.
   PubMedGoogle Scholar
• Stevenson A, Kirresh A, Conway S, et al. Hydroxychloroquine use in COVID-19: is the risk of cardiovascular toxicity justified? Open Heart. 2020 Aug;7(2):e001362.
   PubMed Web of Science ®Google Scholar
• Ren L, Xu W, Overton JL, et al. Assessment of Chloroquine and Hydroxychloroquine Safety Profiles: a Systematic Review and Meta-Analysis. Front Pharmacol. 2020;11:562777.
   PubMed Web of Science ®Google Scholar
• Koronkowski M, Eisenhower C, Marcum Z. An Update on Geriatric Medication Safety and Challenges Specific to the Care of Older Adults. 2016;24(3):37–40. Ann Longterm Care.
   PubMedGoogle Scholar
• Charlesworth CJ, Smit E, Lee DS, et al. Polypharmacy Among Adults Aged 65 Years and Older in the United States: 1988-2010. J Gerontol A Biol Sci Med Sci. 2015;70(8):989–995.
   PubMed Web of Science ®Google Scholar
• Abegaz TM, Birru EM, Mekonnen GB. Potentially inappropriate prescribing in Ethiopian geriatric patients hospitalized with cardiovascular disorders using START/STOPP criteria. PLoS One. 2018;13(5):e0195949.
   PubMed Web of Science ®Google Scholar
• Caughey GE, Hillen JB, Bacon S, et al. Implementation of medication-related indicators of potentially preventable hospitalizations in a national chronic disease management program for older patients with multimorbidity. Int J Qual Health Care. 2019;31(2):133–139.
   PubMed Web of Science ®Google Scholar
• Houlind MB, Andersen AL, Treldal C, et al. Review Including Deprescribing for Older Patients in an Emergency Department: a Longitudinal Feasibility Study. J Clin Med. 2020;9(2):348.
   Web of Science ®Google Scholar
• Da Costa FA, Periquito C, Carneiro MC, et al. Potentially inappropriate medications in a sample of Portuguese nursing home residents: does the choice of screening tools matter? Int J Clin Pharm. 2016;38(5):1103–1111.
   PubMed Web of Science ®Google Scholar
• Mecca MC, Thomas JM, Niehoff KM, et al. Assessing an Interprofessional Polypharmacy and Deprescribing Educational Intervention for Primary Care Post-graduate Trainees: a Quantitative and Qualitative Evaluation. J Gen Intern Med. 2019;34(7):1220–1227.
   PubMed Web of Science ®Google Scholar
• Pasina L, Brignolo Ottolini B, Cortesi L, et al. Need for deprescribing in hospital elderly patients discharged with a limited life expectancy: the REPOSI study. Med Princ Pract. 2019;28(6):501–508.
   PubMed Web of Science ®Google Scholar
• Farrell B, Tsang C, Raman-Wilms L, et al. What are priorities for deprescribing for elderly patients? Capturing the voice of practitioners: a modified delphi process. PLoS One. 2015;10(4):e0122246.
   PubMed Web of Science ®Google Scholar
• Franken PR, Woltersdorf R. Belastung der Nieren bei älterer Patientin mit Herzinsuffizienz [Risk of renal dysfunction in an elderly patient with chronic heart failure]. Med Monatsschr Pharm. 2016;39(10):421–426. German.
   PubMedGoogle Scholar
• Salgueiro E, Elizarde BC, Elola AI, et al. The most common STOPP/START criteria in Spain. A review of the literature. Rev Esp Geriatr Gerontol. 2018;53(5):274–278.
   PubMedGoogle Scholar
• Qi K, Reeve E, Hilmer SN, et al. Older peoples’ attitudes regarding polypharmacy, statin use and willingness to have statins deprescribed in Australia. Int J Clin Pharm. 2015;37(5):949–957.
   PubMed Web of Science ®Google Scholar
• Galli TB, Reis WC, Andrzejevski VM. Potentially inappropriate prescribing and the risk of adverse drug reactions in critically ill older adults. Pharm Pract (Granada). 2016;14(4):818.
   PubMedGoogle Scholar
• Holton A, Boland F, Gallagher P, et al. Longitudinal prevalence of potentially serious alcohol-medication interactions in community-dwelling older adults: a prospective cohort study. Eur J Clin Pharmacol. 2019;75(4):569–575.
   PubMed Web of Science ®Google Scholar
• Victor K, Skelly M, Mulcahy K, et al. A review and study of aspirin utilization for the primary prevention of cardiovascular events in a psychiatric population. Int Clin Psychopharmacol. 2018;33(5):274–281.
   PubMed Web of Science ®Google Scholar
• Green AR, Reifler LM, Boyd CM, et al. Medication Profiles of Patients with Cognitive Impairment and High Anticholinergic Burden. Drugs Aging. 2018;35(3):223–232.
   PubMed Web of Science ®Google Scholar
• Marzi MM, Pires MS, Quaglia NB. Ingredientes Farmacéuticos Activos Potencialmente Inapropiados en Adultos Mayores: lista IFAsPIAM: panel de Consenso Argentino. Value Health Reg Issues. 2018;17:38–55.
   PubMedGoogle Scholar
• Pandraud-Riguet I, Bonnet-Zamponi D, Bourcier E, et al. Monitoring of Potentially Inappropriate Prescriptions in Older Inpatients: a French Multicenter Study. J Am Geriatr Soc. 2017;65(12):2713–2719.
   PubMed Web of Science ®Google Scholar
• Hwang HJ, Kim SH, Lee KS. Potentially Inappropriate Medications in the Elderly in Korean Long-Term Care Facilities. Drugs Real World Outcomes. 2015;2(4):355–361.
   PubMedGoogle Scholar
• Heppenstall CP, Broad JB, Boyd M, et al. Medication use and potentially inappropriate medications in those with limited prognosis living in residential aged care. Australas J Ageing. 2016;35(2):E18–24.
   PubMed Web of Science ®Google Scholar
• Dills H, Shah K, Messinger-Rapport B, et al. Deprescribing Medications for Chronic Diseases Management in Primary Care Settings: a Systematic Review of Randomized Controlled Trials. J Am Med Dir Assoc. 2018;19(11):923–935.e2.
   PubMed Web of Science ®Google Scholar
• Luymes CH, Van Der Kleij RM, Poortvliet RK, et al. Deprescribing Potentially Inappropriate Preventive Cardiovascular Medication: barriers and Enablers for Patients and General Practitioners. Ann Pharmacother. 2016;50(6):446–454.
   PubMed Web of Science ®Google Scholar
• Luymes CH, Boelhouwer NJ, Poortvliet RK, et al. Understanding deprescribing of preventive cardiovascular medication: a Q-methodology study in patients. Patient Prefer Adherence. 2017;11:975–984.
   PubMed Web of Science ®Google Scholar
• Luymes CH, Poortvliet RKE, Van Geloven N, et al. Deprescribing preventive cardiovascular medication in patients with predicted low cardiovascular disease risk in general practice - the ECSTATIC study: a cluster randomised non-inferiority trial. BMC Med. 2018;16(1):5.
   PubMed Web of Science ®Google Scholar
• Nuñez-Montenegro A, Montiel-Luque A, Martin-Aurioles E, Garcia-Dillana F, Krag-Jiménez M, González-Correa JA. Evaluation of Inappropriate Prescribing in Patients Older than 65 Years in Primary Health Care. J Clin Med. 2019;8(3): 305.
   Web of Science ®Google Scholar
• Chiapella LC, Menna JM, Mamprin ME. Potentially Inappropriate Medications in Elderly Ambulatory Patients: a Comparative Study between a Primary Health Care Center and a Community Pharmacy. Value Health Reg Issues. 2018;17:119–125.
   PubMedGoogle Scholar
• Saqlain M, Ali H, Kamran S, et al. Potentially inappropriate medications use and its association with health-related quality of life among elderly cardiac patients. Qual Life Res. 2020;29(10):2715–2724.
   PubMed Web of Science ®Google Scholar
• Primejdie DP, Bojita MT, Popa A. Potentially inappropriate medications in elderly ambulatory and institutionalized patients: an observational study. BMC Pharmacol Toxicol. 2016;17(1):38.
   PubMed Web of Science ®Google Scholar
• Thevelin S, Mounaouar LE, Marien S, et al. Potentially Inappropriate Prescribing and Related Hospital Admissions in Geriatric Patients: a Comparative Analysis between the STOPP and START Criteria Versions 1 and 2. Drugs Aging. 2019;36(5):453–459.
   PubMed Web of Science ®Google Scholar
• É G, Hertzog M, Vogel T, et al. Potentially inappropriate prescribing cardiovascular medications in the aged population: prospective study in a district hospital centre (France). Presse Med. 2015;44(2):e41–50.
   PubMedGoogle Scholar
• Blanco-Reina E, García-Merino MR, Ocaña-Riola R, et al. Inappropriate Prescribing in Community-Dwelling Older Patients Using the Updated Version of STOPP-START Criteria: a Comparison of Profiles and Prevalences with Respect to the Original Version. PLoS One. 2016;11(12):e0167586.
   PubMed Web of Science ®Google Scholar
• Parodi López N, Villán Villán YF, Granados Menéndez MI, et al. Potentially inappropriate prescribing in patients over 65 years-old in a primary care health centre. Aten Primaria. 2014;46(6):290–297.
   PubMed Web of Science ®Google Scholar
• Machado-Alba JE, Giraldo-Giraldo C, Aguirre Novoa A. Results of an intervention to reduce potentially inappropriate prescriptions of beta blockers and calcium channel blockers. Rev Calid Asist. 2016;31(3):134–140.
   PubMed Web of Science ®Google Scholar