216
Views
18
CrossRef citations to date
0
Altmetric
Research Article

Inhibition of Parasite Protein Kinase C by New Antileishmanial Imidazolidin-2-one Compounds

, , , , &
Pages 443-447 | Published online: 30 Sep 2008

  • Hofmann, J. (2001) "Modulation of protein kinase C in antitumor treatment", Review of Physiology and Biochemical Pharmacology 142, 1-96.
  • Epand, R.M. and Lester, D.S. (1990) "The role of membrane biophysical properties in the regulation of protein kinase C activity", Trends in Pharmacological Science 11, 317-320.
  • Clark, E.A., Leach, K.L., Trojanowski, J.Q. and Lee, V.M. (1991) "Characterization and differential distribution of the three major human protein kinase C isoenzymes (PKC alpha, PKC beta and PKC gamma) of the central nervous system in normal and Alzheimer's disease brains", Laboratory Investigation 64, 35-44.
  • Xiao, H., Goldthwait, D.A. and Mapstone, T. (1994) "Identification of four protein kinase C isoforms in human glioblastoma cell lines: PKC alpha, gamma, epsilon and zeta", Journal of Neurosurgy 81, 734-740.
  • Blair, K., Bennett, J.L. and Pax, R. (1988) "Schistosoma mansoni: evidence for protein kinase C-like modulation of muscle activity", Experimental Parasitology 66, 243-252.
  • Gomez, M.L., Erijman, L., Arauzo, S., Torres, H.N. and Tellez-Iñon, M.T. (1989) "Protein kinase C in Trypanosoma cruzi epimastigote forms: partial purification and characterization", Molecular and Biochemical Parasitology 36, 101-108.
  • Robert-Gagneaux, F., Creuzet, C., Dupouy-Camet, J. and Roisin, M.P. (2000) "Involvement of the mitogen-actived protein (MAP) kinase signalling pathway in host cell invasion by Toxoplasma gondii", Parasite 7, 95-101.
  • De Meester, F., Mirelman, D., Stolarsky, T. and Lester, D.S. (1990) "Identification of protein kinase C and its potential substrate in Entamoeba histolytica", Comparative Biochemistry and Physiology 97B, 707-711.
  • Keith, K., Hide, G. and Tait, A. (1990) "Characterization of protein kinase C like activities in Trypanosoma brucei", Molecular and Biochemical Parasitology 43, 107-116.
  • Bradshaw, D., Hill, C.H., Nixon, J.S. and Wilkinson, S.E. (1993) "Therapeutic potential of protein kinase inhibitors", Agents Actions 38, 135-147.
  • Ruegg, U.T. and Burgess, G.M (1989) "Staurosporine, K252 and UCN-0l potent but nonspecific inhibitors of protein kinases", Trends in Biochemistry Science 10, 218-220.
  • Alvarez, N.F. and Le Pape, P. (2001) "Leishmania protein kinase C: identification and participation in the invasion process", Parasite, (submitted).
  • Abdala, H., Robert, J.-M., Le Pape, P., Wielgosz, G., Robert-Piessard, S. and Le Baut, G. (2000) "Synthesis and antileishmanial activity of new l-(pyridin-2-yl) imidazolidin2-ones derived from 2-amino-4,6-dimethylpyridine", Arzneimittel-Forschung//Drug Research 50, 479-484.
  • Robert-Piessard, S., Le Baut, G., Courant, G., Brion, J., Sparfel, J.-D., Bouhayat, L, Petit, S., Sanchez, J.-Y, Jugé, R.-Y., Grimaud, M. and Welin, N. (1990) "Non-acidic antiinflammatory compounds: activity of N-(4,6-dimethyl-2-pyridinyl) benzamides and derivatives", European Journal of Medicinal Chemistry 25, 9-19.
  • Le Pape, P., Zidane, M., Abdala, H. and More, M.-T. (2000) "A glycoprotein isolated from the sponge Pachymatismine johnstonii has anti-leishmanial activity", Cell Biology International 24, 51-56.
  • Le Pape, P., Abdala, H., Pagniez, F., Robert, J.-M and Le Baut, G. (1999) "Activity of N-lutidinyl-arylcarboxamides against Leishmania donovani and Leishmania braziliensis", Acta Parasitologica 44, 156-159.
  • Pagniez, F. and Le Pape, P. (2001) "New fluorometric screening test for possible antifungal drugs", Journal de Mycologie Médicale 11, 73-78.
  • Berman, J.D. (1988) "Inhibition of Leishmania protein kinase by antileishmanial drugs", American Journal of Tropical Medicine and Hygiene 38, 298-303.
  • Khaw, M. and Panosian, C.B. (1995) "Human antiprotozoal therapy: past, present and future", Clinical and Microbiological Review 8, 427-439.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.