Advanced search
Publication Cover
Journal of Enzyme Inhibition and Medicinal Chemistry Volume 17, 2002 - Issue 1
Submit an article Journal homepage
295
Views
14
CrossRef citations to date
0
Altmetric
Research Article

Carbonic Anhydrase Inhibitors With Strong Topical Antiglaucoma Properties Incorporating a 4-(2-amino-pyrimidin-4-yl-amino)-benzenesulfonamide Scaffold

Angela Casini Università degli Studi di Firenze, Polo Scientifico, Laboratorio di Chimica Bioinorganica, Rm. 188, Via della Lastruccia, 3, I-50019 Sesto Fiorentino Firenze, Italy
,
Francesco Mincione Università degli Studi, Istituto Oculistico, Viale Morgagni 85, I-50134 Firenze, and U.O. Oculistica Az. USL 3, Val di Nievole, Ospedale di Pescia, Pescia, Italy
,
Daniela Vullo Università degli Studi di Firenze, Polo Scientifico, Laboratorio di Chimica Bioinorganica, Rm. 188, Via della Lastruccia, 3, I-50019 Sesto Fiorentino Firenze, Italy
,
Luca Menabuoni Ospedale San Giovanni di Dio, U.O. Oculistica, Via Torregalli 3, I-50123, Firenze, Italy
,
Andrea Scozzafava CSGI, c/o Università degli Studi di Firenze, Via Gino Capponi 7, I-50121, Firenze, Italy
&
Claudiu T. Supuran Università degli Studi di Firenze, Polo Scientifico, Laboratorio di Chimica Bioinorganica, Rm. 188, Via della Lastruccia, 3, I-50019 Sesto Fiorentino Firenze, Italy
Pages 9-18 | Published online: 30 Sep 2008

  • Supuran, C.T. and Scozzafava, A. (2001), Curr. Med. Chem. Imm., Endoc., Metab. Agents 1, 61-97.
  • Supuran, C.T. and Scozzafava, A. (2000), Exp. Opin. Ther.Patents 10, 575-600.
  • Supuran, C.T. (1994) "Carbonic anhydrase inhibitors", In: Puscas, I., eds, Carbonic Anhydrase and Modulation of Physiologic and Pathologic Processes in the Organism (Helicon, Timisoara, Roumania), pp 29-111.
  • Maren, T.H. (2000) "Carbonic anhydrase inhibition in ophthalmology: aqueous humor secretion and development of sulphonamide inhibitors", The Carbonic Anhydrases--New Horizons (Birkhäuser, Basel), pp 425-436.
  • Maren, T.H., Jankowska, L., Sanyal, G. and Edelhauser, G.F. (1983), Exp. Eye Res. 36, 457-480.
  • Sugrue, M.F. (2000), Progr. Ret. Eye Res. 19, 87-112.
  • Silver, L.H. (2000), Surv. Ophthalmol. 44(Suppl. 2), 147-153.
  • Konowal, A., Morrison, J.C., Brown, S.V., Cooke, D.L., Maguire, L.J., Verdier, D.V., Fraunfelder, F.T., Dennis, R.F., Epstein, R.J. and Am (1999), J. Ophthalmol. 127, 403-406.
  • Aalto-Korte, K. (1998), Contact Dermatitis 39, 206.
  • Carlsen, J., Durcan, J., Swartz, M. and Crandall, A. (1999), Arch. Ophthalmol. 117, 1087-1088.
  • Thoe Schwartzenberg, G.W. and Trope, G.E. (1999), Can. J. Ophthalmol. 34, 93-94.
  • Mansoor, U.F., Zhang, YR. and Blackburn, G.M. (2000) "The design of new carbonic anhydrase inhibitors", In: Chegwidden, W.R., Edwards, Y. and Carter, N., eds, The Carbonic Anhydrases--New Horizons (Birkhäuser, Basel), pp 437-460.
  • Scozzafava, A., Menabuoni, L., Mincione, F., Briganti, F., Mincione, G. and Supuran, C.T. (2000), J. Med. Chem. 43, 4542-4551.
  • Casini, A., Scozzafava, A., Mincione, F., Menabuoni, L., Hies, M.A. and Supuran, C.T. (2000), J. Med. Chem. 43, 4884-4892.
  • Chen, H.H., Gross, S., Liao, J., McLaughlin, M., Dean, T., Sly, W.S. and May, J.A. (2000), Bioorg. Med. Chem. 8, 957-975.
  • Scozzafava, A., Menabuoni, L., Mincione, F., Briganti, F., Mincione, G. and Supuran, C.T. (1999), J. Med. Chem. 42, 2641-2650.
  • Scozzafava, A., Briganti, F., Mincione, G., Menabuoni, L., Mincione, F. and Supuran, C.T. (1999), J. Med. Chem. 42, 3690-3700.
  • Borras, J., Scozzafava, A., Menabuoni, L., Mincione, F., Briganti, F., Mincione, G. and Supuran, CT (1999), Bioorg. Med. Chem. 7, 2397-2406.
  • Supuran, CT., Briganti, F., Tilli, S., Chegwidden, W.R. and Scozzafava, A. (2001), Bioorg. Med. Chem. 9, 703-714.
  • Ilies, M., Supuran, C.T., Scozzafava, A., Casini, A., Mincione, F., Menabuoni, L., Caproiu, M.T., Maganu, M. and Banciu, M.D. (2000), Bioorg. Med. Chem. 8, 2145-2155.
  • Scozzafava, A., Menabuoni, L., Mincione, F., Mincione, G. and Supuran, CT. (2001), Bioorg. Med. Chem. Lett. 11, 575-582.
  • Supuran, CT and Clare, B.W. (1999), Eur. J. Med. Chem. 34, 41-50.
  • Clare, B.W. and Supuran, CT (1999), Eur. J. Med. Chem. 34, 463-474.
  • Clare, B.W. and Supuran, CT. (2000), Eur. J. Med. Chem. 35, 859-865.
  • Scozzafava, A. and Supuran, CT. (1999), J. Enz. Inhib. 14, 343-363.
  • Lindskog, S., Behravan, G., Engstrand, C., Foreman, C., Jonsson, B.H., Liang, Z., Ren, X. and Xue, Y. (1991) In: Botrè, F., Gros, G. and Storey, B.T., eds, Carbonic Anhydrase-From Biochemistry and Genetics to Physiology and Clinical Medicine (VCH, Weinheim), pp 1-13.
  • Behravan, G., Jonsson, B.H. and Lindskog, S. (1990), Eur. J. Biochem. 190, 351-357.
  • Khalifah, R.G., Strader, D.J., Bryant, S.H. and Gibson, S.M. (1977), Biochemistry 16, 2241-2247.
  • Lindskog, S. and Coleman, J.E. (1964), Proc. Natl. Acad Sci. USA 70, 2505-2508.
  • Steiner, H., Jonsson, B.H., Lindskog, S. and Eur (1975), J. Biochem. 59, 253-259.
  • Maren, T.H., Wynns, G.G. and Wistrand, R.J. (1993), Mol. Pharmacol. 44, 901-906.
  • Pocker, Y. and Stone, J.T. (1967), Biochemistry 6, 668-678.
  • Baird, T.T., Waheed, A., Okuyama, T., Sly, W.S. and Fierke, C.A. (1997), Biochemistry 36, 2669-2678.
  • Maren, T.H., Brechue, W.F. and Bar-Ilan, A. (1992), Exp. Eye Res. 55, 73-79.
  • Brechue, W.F. and Maren, T.H. (1993), Invest. Ophthalmol. Vis. Sci. 34, 2581-2587.
  • Sugrue, M.F., Gautheron, P., Mallorga, P., Nolan, T.E., Graham, S.L., Schwam, H., Shepard, K.L. and Smith, R.L. (1990), Br J. Pharmacol. 99, 59-64.
  • Supuran, C.T., Hies, M.A., Scozzafava, A. and Eur (1998), J. Med. Chem. 33, 739-751.
  • Pierce, Jr, W.M., Sharir, M., Waite, K.J., Chen, D. and Kaysinger, K.K. (1993), Proc. Soc. Exp. Biol. Med. 203, 360-365.
  • Sharir, M., Pierce, Jr, W.M., Chen, D. and Zimmerman, T.J. (1994), Exp. Eye Res. 58, 107-116.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.