Effect of a bis-thiazolium compound on the biosynthesis of Plasmodium falciparum phospholipids

References

• Tripathi RP, Mishra RC, Dwivedi N, Tewari N, Verma SS. Current status of malaria control. Curr Med Chem 2005; 12: 2643–2659.
   PubMed Web of Science ®Google Scholar
• Gornicki P. Apicoplast fatty acid biosynthesis as a target for medical intervention in apicomplexan parasites. Int J Parasitol 2003; 33: 885–896.
   PubMed Web of Science ®Google Scholar
• Ancelin ML, Calas M, Vidal-Sailhan V, Herbute S, Ringwald P, Vial HJ. Potent inhibitors of Plasmodium phospholipid metabolism with a broad spectrum of in vitro antimalarial activities. Antimicrob Agents Chemother 2003; 47: 2590–2597.
   PubMed Web of Science ®Google Scholar
• Mitamura T, Palacpac NM. Lipid metabolism in Plasmodium falciparum-infected erythrocytes: possible new targets for malaria chemotherapy. Microbes Infect 2003; 5: 545–552.
   PubMedGoogle Scholar
• Roth EF, Jr., Calvin MC, Max-Audit I, Rosa J, Rosa R. The enzymes of the glycolytic pathway in erythrocytes infected with Plasmodium falciparum malaria parasites. Blood 1988; 72: 1922–1925.
   PubMed Web of Science ®Google Scholar
• Ancelin ML, Vial HJ. Quaternary ammonium compounds efficiently inhibit Plasmodium falciparum growth in vitro by impairment of choline transport. Antimicrob Agents Chemother 1986; 29: 814–820.
   PubMed Web of Science ®Google Scholar
• Wengelnik K, Vidal V, Ancelin ML, Cathiard AM, Morgat JL, Kocken CH, Calas M, Herrera S, Thomas AW, Vial HJ. A class of potent antimalarials and their specific accumulation in infected erythrocytes. Science 2002; 295: 1311–1314.
   PubMed Web of Science ®Google Scholar
• Hamze A, Rubi E, Arnal P, Boisbrun M, Carcel C, Salom-Roig X, Maynadier M, Wein S, Vial H, Calas M. Mono- and bis-thiazolium salts have potent antimalarial activity. J Med Chem 2005; 48: 3639–3643.
   PubMed Web of Science ®Google Scholar
• Richier E, Biagini GA, Wein S, Boudou F, Bray PG, Ward SA, Precigout E, Calas M, Dubremetz JF, Vial HJ. Potent antihematozoan activity of novel bisthiazolium drug T16: evidence for inhibition of phosphatidylcholine metabolism in erythrocytes infected with Babesia and Plasmodium spp. Antimicrob Agents Chemother 2006; 50: 3381–3388.
   PubMedGoogle Scholar
• Lebaron FN, Folch J. The effect of pH and salt concentration on aqueous extraction of brain proteins and lipoproteins. J Neurochem 1959; 4: 1–8.
   PubMedGoogle Scholar
• Elabbadi N, Ancelin ML, Vial HJ. Use of radioactive ethanolamine incorporation into phospholipids to assess in vitro antimalarial activity by the semiautomated microdilution technique. Antimicrob Agents Chemother 1992; 36: 50–55.
   PubMedGoogle Scholar
• Vial HJ, Ancelin ML, Thuet MJ, Philippot JR. Phospholipid metabolism in Plasmodium-infected erythrocytes: guidelines for further studies using radioactive precursor incorporation. Parasitology 1989; 98 Pt 3: 351–357.
   PubMedGoogle Scholar
• Nicolas O, Margout D, Taudon N, Wein S, Calas M, Vial HJ, Bressolle FM. Pharmacological properties of a new antimalarial bisthiazolium salt, T3, and a corresponding prodrug, TE3. Antimicrob Agents Chemother 2005; 49: 3631–3639.
   PubMed Web of Science ®Google Scholar
• Ancelin ML, Vial HJ. Regulation of phosphatidylcholine biosynthesis in Plasmodium-infected erythrocytes. Biochim Biophys Acta 1989; 1001: 82–89.
   PubMedGoogle Scholar
• Vance JE, Vance DE. Phospholipid biosynthesis in mammalian cells. Biochem Cell Biol 2004; 82: 113–128.
   PubMedGoogle Scholar
• Kent C. Eukaryotic phospholipid biosynthesis. Annu Rev Biochem 1995; 64: 315–343.
   PubMed Web of Science ®Google Scholar
• Carman GM, Kersting MC. Phospholipid synthesis in yeast: regulation by phosphorylation. Biochem Cell Biol 2004; 82: 62–70.
   PubMedGoogle Scholar
• Vial HJ, Eldin P, Tielens AG, van Hellemond JJ. Phospholipids in parasitic protozoa. Mol Biochem Parasitol 2003; 126: 143–154.
   PubMedGoogle Scholar
• Blusztajn JK, Wurtman RJ. Choline biosynthesis by a preparation enriched in synaptosomes from rat brain. Nature 1981; 290: 417–418.
   PubMed Web of Science ®Google Scholar
• Blusztajn JK, Zeisel SH, Wurtman RJ. Synthesis of lecithin (phosphatidyl choline) from phosphatidylethanolamine in bovine brain. Brain Res 1979; 179: 319–327.
   PubMed Web of Science ®Google Scholar
• Kanipes MI, Henry SA. The phospholipid methyltransferases in yeast. Biochim Biophys Acta 1997; 1348: 134–141.
   PubMedGoogle Scholar
• Vial HJ, Thuet MJ, Broussal JL, Philippot JR. Phospholipid biosynthesis by Plasmodium knowlesi-infected erythrocytes: the incorporation of phospohlipid precursors and the identification of previously undetected metabolic pathways. J Parasitol 1982; 68: 379–391.
   PubMedGoogle Scholar
• Witola WH, Pessi G, El Bissati K, Reynolds JM, Mamoun CB. Localization of the phosphoethanolamine methyltransferase of the human malaria parasite Plasmodium falciparum to the Golgi apparatus. J Biol Chem 2006; 281: 21305–21311.
   PubMedGoogle Scholar
• Pradines B, Fusai T, Daries W, Laloge V, Rogier C, Millet P, Panconi E, Kombila M, Parzy D. Ferrocene-chloroquine analogues as antimalarial agents: in vitro activity of ferrochloroquine against 103 Gabonese isolates of Plasmodium falciparum. J Antimicrob Chemother 2001; 48: 179–184.
   PubMed Web of Science ®Google Scholar
• Pessi G, Kociubinski G, Mamoun CB. A pathway for phosphatidylcholine biosynthesis in Plasmodium falciparum involving phosphoethanolamine methylation. PNAS 2004; 101: 6206–6211.
   PubMedGoogle Scholar
• Pessi G, Choi J-Y, Reynolds JM, Voelker DR, Mamoun CB. In Vivo Evidence for the Specificity of Plasmodium falciparum Phosphoethanolamine Methyltransferase and Its Coupling to the Kennedy Pathway. J. Biol. Chem. 2005; 280: 12461–12466.
   PubMedGoogle Scholar
• Witola WH, Ben Mamoun C. Choline induces transcriptional repression and proteasomal degradation of the malarial phosphoethanolamine methyltransferase. Eukaryot Cell 2007; 6: 1618–1624.
   PubMedGoogle Scholar