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Research Article

Inhibition of protein tyrosine phosphatase 1B by lupeol and lupenone isolated from Sorbus commixta

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Pages 1056-1059 | Received 21 Jul 2008, Accepted 07 Dec 2008, Published online: 23 Jun 2009

References

  • Johnson TO, Ermolieff J, Jirousek MR. Protein tyrosine phosphatase 1B inhibitors for diabetes. Nat Rev Drug Discov 2002;1:696–709.
  • Asante-Appiah E, Kennedy BP. Protein tyrosine phosphatases: the quest for negative regulators of insulin action. Am J Physiol Endocrinol Metab 2003;284:E663–70.
  • Taylor SD, Hill B. Recent advances in protein tyrosine phosphatase 1B inhibitors. Expert Opin Investig Drugs 2004;13:199–214.
  • Bialy L, Waldmann H. Inhibitors of protein tyrosine phosphatases: Next-generation drugs? Angew Chem Int Ed 2005;44:3814–3839.
  • Hong JH, Lee MS, Bae EY, Kim YH, Oh H, Oh WK, Kim BY, Ahn JS. Screening of the inhibitory activity of medicinal plants against protein tyrosine phosphatase 1B. Kor J Pharmacogn 2004;35:16–21.
  • Bae K. The medicinal plants of Korea. Seoul: Kyo-Hak Publishing Co.;2000. p. 236.
  • Kokubun T, Harborne JB, Eagles J, Waterman PG. Antifungal biphenyl compounds are the phytoalexins of the sapwood of Sorbus acuparia. Phytochemistry 1995;40:57–59.
  • Na M, An RB, Min BS, Lee SM, Kim YH, Bae K. Chemical constituents from Sorbus commixta. Nat Prod Sci 2002;8:62–65.
  • Na M, An RB, Lee SM, Min BS, Kim YH, Bae K, Kang SS. Antioxidant compounds from the stem bark of Sorbus commixta. Nat Prod Sci 2002;8:26–29.
  • Sohn EJ, Kang DG, Mun YJ, Woo WH, Lee HS. Anti-atherogenic effects of the methanol extract of Sorbus cortex in atherogenic-diet rats. Biol Pharm Bull 2005;28:1444–1449.
  • Lee SO, Lee HW, Lee IS, Im HG. The pharmacological potential of Sorbus commixta cortex on blood alcohol concentration and hepatic lipid peroxidation in acute alcohol-treated rats. J Pharm Pharmacol 2006;58:685–693.
  • Kim S, Na M, Oh H, Jang J, Sohn CB, Kim BY, Oh WK, Ahn JS. PTP1B inhibitory activity of kaurane diterpenes isolated from Siegesbeckia glabrescens. J Enz Inhib Med Chem 2006;21:379–383.
  • Hamaguchi T, Sudo T, Osada H. RK-682, a potent inhibitor of tyrosine phosphatase VHR, arrested the mammalian cell cycle progression at G1 phase. Chem Biol 2001;8:1209–1220.
  • Na M, Jang J, Njamen D, Mbafor JT, Fomum ZT, Kim BY, Oh WK, Ahn JS. Protein tyrosine phosphatase-1B inhibitory activity of isoprenylated flavonoids isolated from Erythrina mildbraedii. J Nat Prod 2006;69:1572–1576.
  • Wiesmann C, Barr KJ, Kung J, Zhu J, Erlanson DA, Shen W, Fahr BJ, Zhong M, Taylor L, Randal M, McDowell RS, Hansen SK. Allosteric inhibition of protein tyrosine phosphatase 1B. Nat Struc Mol Biol 2004;11:730–737.
  • Geetha T, Varalakshmi P. Anti-inflammatory activity of lupeol and lupeol linoleate in rats. J Ethnopharmacol 2001;76:77–80.
  • Madureira AM, Ascenso JR, Valdeira L, Duarte A, Frade JP, Freitas G, Ferreira MJ. Evaluation of the antiviral and antimicrobial activities of triterpenes isolated from Euphorbia segetalis. Nat Prod Res 2003;17:375–380.
  • Nagaraj M, Sunitha S, Varalakshmi P. Effect of lupeol, a pentacyclic triterpene, on the lipid peroxidation and antioxidant status in rat kidney after chronic cadmium exposure. J Appl Toxicol 2000;20:413–417.
  • Saleem M, Afaq F, Adhami VM, Mukhtar H. Lupeol modulates NF-κB and PI3K/Akt pathways and inhibits skin cancer in CD-1 mice. Oncogene 2004;23:5203–5214.
  • You YJ, Nam NH, Kim Y, Bae K, Ahn BZ. Antiangiogenic activity of lupeol from Bombax ceiba. Phytother Res 2003;17:341–344.
  • Ziegler HL, Staerk D, Christensen J, Hviid L, Hägerstrand H, Jaroszewski JW. In vitro Plasmodium falciparum drug sensitivity assay: inhibition of parasite growth by incorporation of stomatocytogenic amphiphiles into the erythrocyte membrane. Antimicrob Agents Chemother 2002;46:1441–1446.
  • Rajic A, Kweifio-Okai G, Macrides T, Sandeman RM, Chandler DS, Polya GM. Inhibition of serine proteases by anti-inflammatory triterpenoids. Planta Med 2000;66:206–210.
  • Wada S, Iida A, Tanaka R. Screening of triterpenoids isolated from Phyllanthus flexuosus for DNA topoisomerase inhibitory activity. J Nat Prod 2001;64:1545–1547.
  • Ortiz-Andrade RR, García-Jiménez S, Castillo-España P, Ramírez-Avila G, Villalobos-Molina R, Estrada-Soto S. α-Glucosidase inhibitory activity of the methanolic extract from Tournefortia hartwegiana: an anti-hyperglycemic agent. J Ethnopharmacol 2007;109:48–53.
  • Ali H, Houghton PJ, Soumyanath A. α-Amylase inhibitory activity of some Malaysian plants used to treat diabetes; with particular reference to Phyllanthus amarus. J Ethnopharmacol 2006;107:449–455.
  • Na M, Yang S, He L, Oh H, Kim BS, Oh WK, Kim BY, Ahn JS. Inhibition of protein tyrosine phosphatase 1B by ursane-type triterpenes isolated from Symplocos paniculata. Plant Med 2006;72:261–263.
  • Zhang YN, Zhang W, Hong D, Shi L, Shen Q, Li JY, Li J, Hu LH. Oleanolic acid and its derivatives: new inhibitor of protein tyrosine phosphatase 1B with cellular activities. Bioorg Med Chem 2008;16:8697–8705.

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