1,698
Views
8
CrossRef citations to date
0
Altmetric
Research Paper

Synthesis and biological evaluation of 3-arylbenzofuranone derivatives as potential anti-Alzheimer’s disease agents

, , , ORCID Icon &
Pages 805-814 | Received 24 Dec 2019, Accepted 02 Mar 2020, Published online: 18 Mar 2020

References

  • Burns A, Iliffe S. Alzheimer's disease. BMJ 2009;338:b158.
  • Morris M, Knudsen GM, Maeda S, et al. Tau post-translational modifications in wild-type and human amyloid precursor protein transgenic mice. Nat Neurosci 2015;18:1183–9.
  • Glabe CC. Amyloid accumulation and pathogensis of Alzheimer’s disease: significance of monomeric, oligomeric and fibrillar Aβ. Alzheimer’s Dis 2005;38:167–77.
  • Scarpini E, Schelterns P, Feldman H. Treatment of Alzheimer’s disease; current status and new perspectives. Lancet Neurol 2003;2:539–47.
  • Perry EK, Tomlinson BE, Blessed G, et al. Correlation of cholinergic abnormalities with senile plaques and mental test scores in senile dementia. Br Med J 1978;2:1457–9.
  • Youdim MB, Edmondson D, Tipton KF. The therapeutic potential of monoamine oxidase inhibitors. Nat Rev Neurosci 2006;7:295–309.
  • Karlsson D, Fallarero A, Brunhofer G, et al. The exploration of thienothiazines as selective butyrylcholinesterase inhibitors. Eur J Pharm Sci 2012;47:190–205.
  • Nadri H, Pirali-Hamedani M, Moradi A, et al. 5,6-Dimethoxybenzofuran-3-one derivatives: a novel series of dual acetylcholinesterase/butyrylcholinesterase inhibitors bearing benzyl pyridinium moiety. Daru J Pharm Sci 2013;21:15.
  • Khaleghi M, Navidpour L, Sepehrizadeh Z, et al. The sensitization of legionella pneumophila to some antibiotics by reserpine and anti-legionella effects of different benzofuranone derivatives. J Med Bacteriol 2013;2:35–40.
  • Gu Q, Wang RR, Zhang XM, et al. A new benzofuranone and anti-HIV constituents from the stems of Rhus chinensis. Planta Med 2007;73:279–82.
  • de Souza Nunes JP, Da Silva KA, Da Silva GF, et al. The antihypersensitive and antiinflammatory activities of a benzofuranone derivative in different experimental models in mice: the importance of the protein kinase C pathway. Anesth Analg 2014;119:836–46.
  • Padaratz P, Fracasso M, De Campos-Buzzi F, et al. Antinociceptive activity of a new benzofuranone derived from a chalcone. Basic Clin Pharmacol Toxicol 2009;105:257–61.
  • Adediran SA, Cabaret D, Drouillat B, et al. The synthesis and evaluation of benzofuranones as β-lactamase substrates. Bioorg Med Chem 2001;9:1175–83.
  • Rabiee A, Ebrahim-Habibi A, Navidpour L, et al. Benzofuranone derivatives as effective small molecules related to insulin amyloid fibrillation: a structure-function study. Chem Biol Drug Des 2011;78:659–66.
  • Aranda R, Villalba K, Raviña E, et al. Synthesis, binding affinity, and molecular docking analysis of new benzofuranone derivatives as potential antipsychotics. J Med Chem 2008;51:6085–94.
  • Ellman GL, Courtney KD, Andres V, et al. A new and rapid colorimetric determination of acetylcholinesterase activity. Biochem Pharmacol 1961;7:88–95.
  • Holt A, Sharman DF, Baker GB, et al. A continuous spectrophotometric assay for monoamine oxidase and related enzymes in tissue homogenates. Anal Biochem 1997;244:384–92.
  • Youdim MBH, Gross A, Finberg JPM. Rasagiline [N-propargyl-1R(+)-aminoindan], a selective and potent inhibitor of mitochondrial monoamine oxidase B. Br J Pharmacol 2001;132:500–6.
  • Stafford GI, Pedersen PD, Jäger AK, et al. Monoamine oxidase inhibition by southern African traditional medicinal plants. S Afr J Bot 2007;73:384–90.
  • Wang XL, Wang WZ, Li L, et al. Oxidative stress and mitochondrial dysfunction in Alzheimer’s disease. Biochim Biophys Acta 2014;1842:1240–7.
  • Lv ZL, Gao Y, Li J, et al. Synthesis and antitumor activities of 3-arylbenzofunanone analogues. Chem J Chin Univ 2013;34:2531–9.
  • Richman DP, Agius MA. Treatment of autoimmune myasthenia gravis. Neurology 2003;61:1652–61.
  • Liston DR, Nielsen JA, Villalobos A, et al. Pharmacology of selective acetylcholinesterase inhibitors: implications for use in Alzheimer’s disease. Eur J Pharmacol 2004;486:9–17.
  • Kennedy BP, Ziegler MG, Alford M, et al. Early and persistent alterations in prefrontal cortex MAO A and B in Alzheimer’s disease. J Neural Transm 2003;110:789–801.
  • Liang XL, Wang XL, Li Z, et al. Improved in vitro assays of superoxide anion and 1,1-diphenyl- 2-picrylhydrazyl (DPPH) radical-scavenging activity of isoflavones and isoflavone metabolites. J Agric Food Chem 2010;58:11548–52.
  • Yang J, Zhang PP, Hu YH, et al. Synthesis and biological evaluation of 3-arylcoumarins as potential anti-Alzheimer’s disease agents. J Enzyme Inhib Med Chem 2019;34:651–6.