The risks of using allogeneic cell lines for vaccine production: the example of Bovine Neonatal Pancytopenia

References

• Friedrich A, Rademacher G, Weber B, et al. Gehäuftes auftreten von häemorrhagischer diathese infole knockenmarkschädigung bei jungen kälbern. Tierarztl Umsch. 2009;64:423–431.
   Google Scholar
• Bell CR, Scott PR, Sargison ND, et al. Idiopathic bovine neonatal pancytopenia in a Scottish beef herd. Vet Rec. 2010;167:938–940. Epub 2011 Jan 26.
   PubMed Web of Science ®Google Scholar
• Paul-Ehrlich-Institut. Investigating the cause of Bleeding Calf Syndrome. 2011. [cited 2016 Oct 14]. Available from: http://www.pei.de/EN/information/journalists-press/press-releases/2011/02-cause-bleeding-calf-syndrome.html
   Google Scholar
• Reichmann F, Sauter-Louis CFA, Rademacher G, et al. Bovine Neonatal Pancytopenia (BNP) in young calves in Germany on farms with high and low incidences of BNP. Lisbon: Associação Portuguesa de Buiatrics; 2012.
   Google Scholar
• Promed. Bovine Neonatal Pancytopenia (03): New Zealand. 2011. [cited 2016 Oct 14]. Available from: http://www.promedmail.org/
   Google Scholar
• Kappe EC, Halami MY, Schade B, et al. Bone marrow depletion with haemorrhagic diathesis in calves in Germany: characterization of the disease and preliminary investigations on its aetiology. Berl Munch Tierarztl Wochenschr. 2010;123:31–41. Epub 2010 Feb 9.
   PubMed Web of Science ®Google Scholar
• Willoughby K, Gilray J, Maley M, et al. Lack of evidence for circovirus involvement in bovine neonatal pancytopenia. Vet Rec. 2010;166:436–437. Epub 2010 Apr 7.
   PubMed Web of Science ®Google Scholar
• Deutskens F, Lamp B, Riedel CM, et al. Vaccine-induced antibodies linked to bovine neonatal pancytopenia (BNP) recognize cattle major histocompatibility complex class I (MHC I). Vet Res. 42;2011:97. Epub 2011 Sep 1.
   PubMed Web of Science ®Google Scholar
• Foucras G, Corbière F, Tasca C, et al. Alloantibodies against MHC class I: a novel mechanism of neonatal pancytopenia linked to vaccination. J Immunol. 2011;187:6564–6570. Epub 2011 Nov 16.
   PubMed Web of Science ®Google Scholar
• Kasonta R, Sauter-Louis C, Holsteg M, et al. Effect of the vaccination scheme on PregSure® BVD induced alloreactivity and the incidence of Bovine Neonatal Pancytopenia. Vaccine. 2012;30:6649–6655. Epub 2012 Oct 11.
   PubMed Web of Science ®Google Scholar
• Bell CR, MacHugh ND, Connelley TK, et al. Haematopoietic depletion in vaccine-induced neonatal pancytopenia depends on both the titre and specificity of alloantibody and levels of MHC I expression. Vaccine. 2015;33:3488–3496. Epub 2015 Jun 10.
   PubMed Web of Science ®Google Scholar
• Benedictus L, Luteijn RD, Otten H, et al. Pathogenicity of Bovine Neonatal Pancytopenia-associated vaccine-induced alloantibodies correlates with major histocompatibility complex class I expression. Sci Rep. 2015;5:12748. Epub 2015 Aug 4.
   PubMed Web of Science ®Google Scholar
• Pardon B, Steukers L, Dierick J, et al. Haemorrhagic diathesis in neonatal calves: an emerging syndrome in Europe. Transbound Emerg Dis. 2010;57:135–146. Epub 2010 Mar 6.
   PubMed Web of Science ®Google Scholar
• Doll K. Bovine Neonatal Pancytopenia. World Buiatrics Congr 2012. Lisbon: Associação Portuguesa de Buiatrics; 2012 Jun 3–8.
   Google Scholar
• Henniger P, Henniger T, Seehusen F, et al. Causes of death in calves with experimentally induced bovine neonatal pancytopenia (BNP). Berl Munch Tierarztl Wochenschr. 2014;127:61–69. Epub 2014 Feb 5.
   PubMed Web of Science ®Google Scholar
• Bell CR, Rocchi MS, Dagleish MP, et al. Reproduction of bovine neonatal pancytopenia (BNP) by feeding pooled colostrum reveals variable alloantibody damage to different haematopoietic lineages. Vet Immunol Immunopathol. 2013;151:303–314. Epub 2013 Jan 1.
   PubMed Web of Science ®Google Scholar
• Friedrich A, Büttner M, Rademacher G, et al. Ingestion of colostrum from specific cows induces Bovine Neonatal Pancytopenia (BNP) in some calves. BMC Vet Res. 2011;7:10. Epub 2011 Feb 22.
   PubMed Web of Science ®Google Scholar
• Bridger PS, Bauerfeind R, Wenzel L, et al. Detection of colostrum-derived alloantibodies in calves with bovine neonatal pancytopenia. Vet Immunol Immunopathol. 2011;141:1–10. Epub 2011 Jan 29.
   PubMed Web of Science ®Google Scholar
• Bastian M, Holsteg M, Hanke-Robinson H, et al. Bovine Neonatal Pancytopenia: is this alloimmune syndrome caused by vaccine-induced alloreactive antibodies? Vaccine. 2011;29:5267–5275. Epub 2011 May 25.
   PubMed Web of Science ®Google Scholar
• Pardon B, Stuyven E, Stuyvaert S, et al. Sera from dams of calves with bovine neonatal pancytopenia contain alloimmune antibodies directed against calf leukocytes. Vet Immunol Immunopathol. 2011;141:293–300. Epub 2011 Mar 29.
   PubMed Web of Science ®Google Scholar
• Assad A, Amann B, Friedrich A, et al. Immunophenotyping and characterization of BNP colostra revealed pathogenic alloantibodies of IgG1 subclass with specifity to platelets, granulocytes and monocytes of all maturation stages. Vet Immunol Immunopathol. 2012;147:25–34. Epub 2012 May 5.
   PubMed Web of Science ®Google Scholar
• Chucri TM, Monteiro JM, Lima AR, et al. A review of immune transfer by the placenta. J Reprod Immunol. 2010;87:14–20. Epub 2010 Oct 20.
   PubMed Web of Science ®Google Scholar
• Stott GH, Marx DB, Menefee BE, et al. Colostral immunoglobulin transfer in calves I. Period of absorption. J Dairy Sci. 1979;62:1632–1638. Epub 1979 Oct 1.
   PubMed Web of Science ®Google Scholar
• Stott GH, Marx DB, Menefee BE, et al. Colostral immunoglobulin transfer in calves II. The rate of absorption. J Dairy Sci. 1979;62:1766–1773. Epub 1979 Nov 1.
   PubMed Web of Science ®Google Scholar
• Stott GH, Marx DB, Menefee BE, et al. Colostral immunoglobulin transfer in calves. III. Amount of absorption. J Dairy Sci. 1979;62:1902–1907. Epub 1979 Dec 1.
   PubMed Web of Science ®Google Scholar
• Jones BA, Sauter-Louis C, Henning J, et al. Calf-level factors associated with bovine neonatal pancytopenia–a multi-country case-control study. PLoS One. 8;2013:e80619. Epub 2013 Dec 7.
   PubMed Web of Science ®Google Scholar
• Lambton SL, Colloff AD, Smith RP, et al. Factors associated with bovine neonatal pancytopenia (BNP) in calves: a case-control study. PLoS One. 2012;7:e34183. Epub 2012 May 19.
   PubMed Web of Science ®Google Scholar
• Sauter-Louis C, Carlin A, Friedrich A, et al. Case control study to investigate risk factors for bovine neonatal pancytopenia (BNP) in young calves in southern Germany. Prev Vet Med. 2012;105:49–58. Epub 2012 Mar 6.
   PubMed Web of Science ®Google Scholar
• Ministry for Primary Industries NZ. Recall of BVD vaccine in New Zealand. [cited 2016 Oct 14]. Available from: http://www.foodsafety.govt.nz/elibrary/industry/bvd-vaccine-nz.htm
   Google Scholar
• Madin SH, Darby NB Jr. Established kidney cell lines of normal adult bovine and ovine origin. Proc Soc Exp Biol Med. 1958;98:574–576. Epub 1958 Jul 1.
   PubMed Web of Science ®Google Scholar
• Summary of product characteristics: Pregsure BVD. 2009. [cited 2016 Oct 24]. Available from: http://www.vmd.defra.gov.uk/ProductInformationDatabase/SPC_Documents/SPC_135334.doc
   Google Scholar
• Euler KN, Hauck SM, Ueffing M, et al. Bovine neonatal pancytopenia–comparative proteomic characterization of two BVD vaccines and the producer cell surface proteome (MDBK). BMC Vet Res. 2013;9:18. Epub 2013 Jan 25.
   PubMed Web of Science ®Google Scholar
• Benedictus L, Rutten VPMG, Koets AP. Pregnancy boosts vaccine-induced Bovine Neonatal Pancytopenia-associated alloantibodies. Vaccine. 2016;34:1002–1005. Epub 2016 Jan 23.
   PubMed Web of Science ®Google Scholar
• Ballingall KT, Nath M, Holliman A, et al. Lack of evidence for an association between MHC diversity and the development of bovine neonatal pancytopenia in Holstein dairy cattle. Vet Immunol Immunopathol. 2011;141:128–132. Epub 2011 Mar 1.
   PubMed Web of Science ®Google Scholar
• Benedictus L, Otten HG, Van Schaik G, et al. Bovine Neonatal Pancytopenia is a heritable trait of the dam rather than the calf and correlates with the magnitude of vaccine induced maternal alloantibodies not the MHC haplotype. Vet Res. 2014;45:129. Epub 2014 Dec 18.
   PubMed Web of Science ®Google Scholar
• Witt K, Weber CN, Meyer J, et al. Haematological analysis of calves with bovine neonatal pancytopenia. Vet Rec. 2011;169:228. Epub 2011 Jul 29.
   PubMed Web of Science ®Google Scholar
• Bell CR, Kerr MG, Scott PR, et al. Evidence of a high incidence of subclinically affected calves in a herd of cattle with fatal cases of Bovine Neonatal Pancytopenia (BNP). BMC Vet Res. 2014;10:245. Epub 2014 Nov 2.
   PubMed Web of Science ®Google Scholar
• Wagter LC, Mallard BA, Wilkie BN, et al. A quantitative approach to classifying Holstein cows based on antibody responsiveness and its relationship to peripartum mastitis occurrence. J Dairy Sci. 2000;83:488–498. Epub 2000 Apr 6.
   PubMed Web of Science ®Google Scholar
• O’Neill RG, Woolliams JA, Glass EJ, et al. Quantitative evaluation of genetic and environmental parameters determining antibody response induced by vaccination against bovine respiratory syncytial virus. Vaccine. 2006;24:4007–4016. Epub 2006 Mar 4.
   PubMed Web of Science ®Google Scholar
• Harmeyer S, Antonis AFG, Gadd T, et al. Fetal protection against BVDV fetal infection six months after vaccination with a novel inactivated BVDV vaccine. Tierarztl Umsch. 2004;59:663–+.
   Google Scholar
• Ammann VJ, Fecteau G, Hélie P, et al. Pancytopenia associated with bone marrow aplasia in a Holstein heifer. Can Vet J. 1996;37:493–495. Epub 1996 Aug 1.
   PubMed Web of Science ®Google Scholar
• Shimada A, Onozato T, Hoshi E, et al. Pancytopenia with bleeding tendency associated with bone marrow aplasia in a Holstein calf. J Vet Med Sci/Jpn Soc Vet Sci. 2007;69:1317–1319. Epub 2008 Jan 8.
   PubMed Web of Science ®Google Scholar
• Fukunaka M, Toyoda Y, Kobayashi Y, et al. Bone marrow aplasia with pancytopenia and hemorrhage in a Japanese Black calf. J Vet Med Sci/Jpn Soc Vet Sci. 2010;72:1655–1656. Epub 2010 Aug 13.
   PubMed Web of Science ®Google Scholar
• Aubrit F, Perugi F, Léon A, et al. Cell substrates for the production of viral vaccines. Vaccine. 2015;33:5905–5912. Epub 2015 Jul 19.
   PubMed Web of Science ®Google Scholar
• Keller-Stanislawski B, Englund JA, Kang G, et al. Safety of immunization during pregnancy: a review of the evidence of selected inactivated and live attenuated vaccines. Vaccine. 2014;32:7057–7064. Epub 2014 Oct 7.
   PubMed Web of Science ®Google Scholar
• Rasmussen SA, Watson AK, Kennedy ED, et al. Vaccines and pregnancy: past, present, and future. Semin Fetal Neonatal Med. 2014;19:161–169. Epub 2013 Dec 21.
   PubMed Web of Science ®Google Scholar
• Nielsen HS, Witvliet MD, Steffensen R, et al. The presence of HLA-antibodies in recurrent miscarriage patients is associated with a reduced chance of a live birth. J Reprod Immunol. 2010;87:67–73. Epub 2010 Jul 8.
   PubMed Web of Science ®Google Scholar
• Lee J, Romero R, Xu Y, et al. Maternal HLA panel-reactive antibodies in early gestation positively correlate with chronic chorioamnionitis: evidence in support of the chronic nature of maternal anti-fetal rejection. Am J Reprod Immunol. 2011;66:510–526. Epub 2011 Sep 29.
   PubMed Web of Science ®Google Scholar
• Lashley EELO, Meuleman T, Claas FHJ. Beneficial or harmful effect of antipaternal human leukocyte antibodies on pregnancy outcome? A systematic review and meta-analysis. Am J Reprod Immunol. 2013;70:87–103. Epub 2013 Mar 19.
   PubMed Web of Science ®Google Scholar
• Bell CR, Scott PR, Kerr MG, et al. Possible preventive strategy for bovine neonatal pancytopenia. Vet Rec. 2010;167:758. Epub 2011 Jan 25.
   PubMed Web of Science ®Google Scholar
• Danziger-Isakov L, Cherkassky L, Siegel H, et al. Effects of influenza immunization on humoral and cellular alloreactivity in humans. Transplantation. 2010;89:838–844. Epub 2010 Feb 25.
   PubMed Web of Science ®Google Scholar
• Katerinis I, Hadaya K, Duquesnoy R, et al. De novo anti-HLA antibody after pandemic H1N1 and seasonal influenza immunization in kidney transplant recipients. Am J Transplant. 2011;11:1727–1733. Epub 2011 Jun 16.
   PubMed Web of Science ®Google Scholar
• Vermeiren P, Aubert V, Sugamele R, et al. Influenza vaccination and humoral alloimmunity in solid organ transplant recipients. Transpl Int. 2014;27:903–908. Epub 2014 May 7.
   PubMed Web of Science ®Google Scholar
• Tait BD, Süsal C, Gebel HM, et al. Consensus guidelines on the testing and clinical management issues associated with HLA and non-HLA antibodies in transplantation. Transplantation. 2013;95:19–47. Epub 2012 Dec 15.
   PubMed Web of Science ®Google Scholar
• Beigi RH, Fortner KB, Munoz FM, et al. Maternal immunization: opportunities for scientific advancement. Clin Infect Dis. 2014;59(Suppl 7):S408–S414. Epub 2014 Nov 27.
   PubMed Web of Science ®Google Scholar
• Munoz FM, Sheffield JS, Beigi RH, et al. Research on vaccines during pregnancy: protocol design and assessment of safety. Vaccine. 2013;31:4274–4279. Epub 2013 Aug 3.
   PubMed Web of Science ®Google Scholar
• Baxter R, Patriarca PA, Ensor K, et al. Evaluation of the safety, reactogenicity and immunogenicity of FluBlok® trivalent recombinant baculovirus-expressed hemagglutinin influenza vaccine administered intramuscularly to healthy adults 50-64 years of age. Vaccine. 2011;29:2272–2278. Epub 2011 Feb 1.
   PubMed Web of Science ®Google Scholar