References
- Anfinsen CB. Principles that govern the folding of protein chains. Science. 1973 Jul 20;181(4096):223–230.
- Wright PE, Dyson HJ. Intrinsically unstructured proteins: re-assessing the protein structure-function paradigm. J Mol Biol. 1999 Oct 22;293(2):321–331.
- Kriwacki RW, Hengst L, Tennant L, et al. Structural studies of p21Waf1/Cip1/Sdi1 in the free and Cdk2-bound state: conformational disorder mediates binding diversity. Proc Natl Acad Sci U S A. 1996 Oct 15;93(21):11504–11509.
- Chothia C. Hydrophobic bonding and accessible surface area in proteins. Nature. 1974 Mar 01;248(5446):338–339.
- Schalch DS, Gonzalez-Barcena D, Kastin AJ, et al. Plasma gonadotropins after administration of LH-releasing hormone in patients with renal or hepatic failure. J Clin Endocrinol Metab. 1975 Nov;41(5):921–925.
- van der Lee R, Buljan M, Lang B, et al. Classification of intrinsically disordered regions and proteins. Chem Rev. 2014 Jul 9;114(13):6589–6631.
- Darling AL, Uversky VN. Intrinsic disorder and posttranslational modifications: the darker side of the biological dark matter. Front Genet. 2018;9:158.
- Wright PE, Dyson HJ. Intrinsically disordered proteins in cellular signalling and regulation. Nat Rev Mol Cell Biol. 2015 Jan;16(1):18–29.
- Dunker AK, Cortese MS, Romero P, et al. Flexible nets. The roles of intrinsic disorder in protein interaction networks. Febs J. 2005 Oct;272(20):5129–5148.
- Ramamurthy M, Sankar S, Abraham AM, et al. B cell epitopes in the intrinsically disordered regions of neuraminidase and hemagglutinin proteins of H5N1 and H9N2 avian influenza viruses for peptide‐based vaccine development. J Cell Biochem. 2019;120(10):17534–17544.
- Xue B, Uversky VN. Intrinsic disorder in proteins involved in the innate antiviral immunity: another flexible side of a molecular arms race. J Mol Biol. 2014 Mar 20;426(6):1322–1350.
- Xue B, Blocquel D, Habchi J, et al. Structural disorder in viral proteins. Chem Rev. 2014 Jul 9;114(13):6880–6911.
- Olugbile S, Kulangara C, Bang G, et al. Vaccine potentials of an intrinsically unstructured fragment derived from the blood stage-associated Plasmodium falciparum protein PFF0165c. Infect Immun. 2009;77(12):5701–5709.
- Adda CG, MacRaild CA, Reiling L, et al. Antigenic characterization of an intrinsically unstructured protein, plasmodium falciparum merozoite surface protein 2. Infect Immun. 2012;80(12):4177–4185.
- MacRaild Christopher A, Richards Jack S, Anders Robin F, et al. Antibody recognition of disordered antigens. Structure. 2016 Jan 05;24(1):148–157.
- Oldfield CJ, Cheng Y, Cortese MS, et al. Coupled folding and binding with alpha-helix-forming molecular recognition elements. Biochemistry. 2005 Sep 20;44(37):12454–12470.
- Foquet L, Hermsen CC, van Gemert GJ, et al. Vaccine-induced monoclonal antibodies targeting circumsporozoite protein prevent Plasmodium falciparum infection. J Clin Invest. 2014 Jan;124(1):140–144.
- Flück C, Smith T, Beck HP, et al. Strain-specific humoral response to a polymorphic malaria vaccine. Infect Immun. 2004 Nov;72(11):6300–6305.
- Cai X, Zheng W, Pan S, et al. A virus-like particle of the hepatitis B virus preS antigen elicits robust neutralizing antibodies and T cell responses in mice. Antiviral Res. 2018 Jan;149:48–57.
- Esposito X, Zheng V, Musi V, de Chiara C, et al. Structure of the C-terminal domain of Neisseria heparin binding antigen (NHBA), one of the main antigens of a novel vaccine against Neisseria meningitidis. Journal of Biological Chemistry. 2011 Jan;286(48): 41767–41775.
- Kaslow DC, Biernaux S. RTS,S: toward a first landmark on the Malaria Vaccine Technology Roadmap. Vaccine. 2015 Dec 22;33(52):7425–7432.
- Genton B, Betuela I, Felger I, et al. A recombinant blood-stage malaria vaccine reduces Plasmodium falciparum density and exerts selective pressure on parasite populations in a phase 1-2b trial in papua new guinea. J Infect Dis. 2002 Mar 15;185(6):820–827.