945
Views
0
CrossRef citations to date
0
Altmetric
Editorial

The iNTS-GMMA vaccine: a promising step in non-typhoidal Salmonella vaccine development

ORCID Icon, ORCID Icon & ORCID Icon
Pages 918-920 | Received 22 Aug 2023, Accepted 10 Oct 2023, Published online: 19 Oct 2023

References

  • Marchello CS, Fiorino F, Pettini E, et al. Incidence of non-typhoidal Salmonella invasive disease: a systematic review and meta-analysis [10.1016/j.Jinf.2021.06.029]. Journal Of Infection. 2021 2021 Jul 11;83(5):523–532. doi: 10.1016/j.jinf.2021.06.029
  • Marchello CS, Birkhold M, Crump JA, et al. Complications and mortality of non-typhoidal salmonella invasive disease: a global systematic review and meta-analysis [10.1016/s1473-3099(21)00615-0]. The Lancet Infectious Diseases. 2022 2022 Feb 1;22(5):692–705. doi: 10.1016/S1473-3099(21)00615-0
  • Pulford CV, Perez-Sepulveda BM, Canals R, et al. Stepwise evolution of Salmonella Typhimurium ST313 causing bloodstream infection in Africa. Nat Microbiol. 2021 2021 Mar 1;6(3):327–338. doi: 10.1038/s41564-020-00836-1
  • MacLennan CA. Antibodies and protection against invasive Salmonella disease [opinion]. Front Immunol. 2014 [2014 Dec 22];5. doi: 10.3389/fimmu.2014.00635
  • MacLennan CA, Gondwe EN, Msefula CL, et al. The neglected role of antibody in protection against bacteremia caused by nontyphoidal strains of Salmonella in African children. J Clin Invest query. 2008 Apr;118(4):1553–1562. doi: 10.1172/JCI33998
  • Gondwe EN, Molyneux ME, Goodall M, et al. Importance of antibody and complement for oxidative burst and killing of invasive nontyphoidal Salmonella by blood cells in Africans. Proc Natl Acad Sci U S A. 2010 Feb 16;107(7):3070–3075. doi: 10.1073/pnas.0910497107
  • Nyirenda TS, Gilchrist JJ, Feasey NA, et al. Sequential acquisition of T cells and antibodies to nontyphoidal Salmonella in Malawian children. J Infect Dis. 2014 Jul 1;210(1):56–64. doi: 10.1093/infdis/jiu045
  • MacLennan CA, Gilchrist JJ, Gordon MA, et al. Dysregulated humoral immunity to nontyphoidal Salmonella in HIV-infected African adults. Science. 2010 Apr 23;328(5977):508–512. doi: 10.1126/science.1180346
  • Gil-Cruz C, Bobat S, Marshall JL, et al. The porin OmpD from nontyphoidal Salmonella is a key target for a protective B1b cell antibody response. Proc Natl Acad Sci U S A. 2009 Jun 16;106(24):9803–9808. doi: 10.1073/pnas.0812431106
  • Goh YS, Armour KL, Clark MR, et al. Igg subclasses targeting the flagella of Salmonella enterica serovar Typhimurium can mediate phagocytosis and bacterial killing. J Vaccines Vaccin. 2016 May 30;7(3). doi: 10.4172/2157-7560.1000322
  • Mastroeni P, Villarreal-Ramos B, Hormaeche CE. Adoptive transfer of immunity to oral challenge with virulent salmonellae in innately susceptible BALB/c mice requires both immune serum and T cells. Infect Immun. 1993 Sep;61(9):3981–3984. doi: 10.1128/iai.61.9.3981-3984.1993
  • Obiero CW, Ndiaye AGW, Scire AS, et al. A phase 2a randomized study to evaluate the safety and immunogenicity of the 1790GAHB generalized modules for membrane antigen vaccine against Shigella sonnei administered intramuscularly to adults from a shigellosis-endemic country. Front Immunol. 2017;8:1884. doi: 10.3389/fimmu.2017.01884
  • De Benedetto G, Alfini R, Cescutti P, et al. Characterization of O-antigen delivered by generalized modules for membrane antigens (GMMA) vaccine candidates against nontyphoidal Salmonella. Vaccine. 2017 Jan 11;35(3):419–426. doi: 10.1016/j.vaccine.2016.11.089
  • Micoli F, Rondini S, Alfini R, et al. Comparative immunogenicity and efficacy of equivalent outer membrane vesicle and glycoconjugate vaccines against nontyphoidal Salmonella. Proc Natl Acad Sci U S A. 2018 Oct 9;115(41):10428–10433. doi: 10.1073/pnas.1807655115
  • Fiorino F, Pettini E, Koeberling O, et al. Long-term anti-bacterial immunity against systemic infection by Salmonella enterica serovar Typhimurium elicited by a GMMA-Based vaccine. Vaccines (Basel). 2021 May 12;9(5):495. doi: 10.3390/vaccines9050495