Is 100% oxygen necessary for the resuscitation of newborn infants?

References

• Saugstad OD, Rootwelt T, Aalen O. Resuscitation of asphyxiated newborn infants with room air or oxygen: an international controlled trial: the Resair 2 study. Pediatrics 1998;102:e1–7
   Google Scholar
• Kattwinkel J, Niermeyer S, Nadkarni V. et al. An advisory statement from the Pediatric Working Group of the Inter-national Liaison Committee on Resuscitation: resuscitation of the newly born infant. Pediatrics 1999;103 :e56
   Google Scholar
• LevineD,Davis J.Resuscitation with 100% oxygen: should wechange our ways?Pediatr Res 2001;50:432
   PubMed Web of Science ®Google Scholar
• JankovR,NegusA,Tanswell A.Antioxidantastherapyinthe newborn: some words of caution. Pediatr Res 2001;50:681–7
   PubMed Web of Science ®Google Scholar
• Saugstad OD. Is oxygen more toxic than currently believed? Pediatrics 2001;108:1203–5
   PubMed Web of Science ®Google Scholar
• Letkowitz W. Oxygen and resuscitation: beyond the myth. Pediatrics 2002;109:517–19
   PubMed Web of Science ®Google Scholar
• Green D, Reed J. Mitochondria and apoptosis. Science 1998; 281:1309–12
   PubMed Web of Science ®Google Scholar
• Forman H, Boveris A. Free Radicals in Biology. New York: Academic Press, 1982
   Google Scholar
• Kamata H, Hirata H. Redox regulation of cellular signalling. Cell Signal 1999;11:1–14
   PubMed Web of Science ®Google Scholar
• O'Donovan D, Fernandes C. Mitochondrial glutathione and oxidative stress: implications for pulmonary oxygen toxicity in premature infants. Mol Genet Metab 2000;71:352–8
   PubMed Web of Science ®Google Scholar
• Wallace K, Eells J, Madeira V. et al. Mitochondrial mediated cell injury: Sympoxium overview. Fundam Appl Toxicol 1997;38:23–37
   Google Scholar
• Burchfield D. Physiology of resuscitation. In Polin R, Fox W, eds. Fetal and Neonatal Physiology, 2nd edn. Philadelphia: WB Saunders, 1998:1023–31
   Google Scholar
• Saugstad O. Hypoxanthine as an indicator of hypoxia: its role in health and disease through free radical production. Pediatr Res 1988;23:143–50
   PubMed Web of Science ®Google Scholar
• Saugstad O. Mechanisms of tissue injury by oxygen radicals: implications for neonatal disease. Acta Paediatr 1996;85:1–4
   PubMed Web of Science ®Google Scholar
• Dunn P. Dr. James Blundell (1790-1878) and neonatal resuscitation. Arch Dis Child 1989;64:494–5
   PubMed Web of Science ®Google Scholar
• Raju TN. History of neonatal resuscitation: tales of heroism and desperation. Neonat Intensive Care 2001;14:35–40
   Google Scholar
• Bonnaire E. Inhalations of oxygen in the newborn. Arch Pediatr 1891;8:769
   Google Scholar
• Haldane JS. The therapeutic administration of oxygen. Br Med J1917:181–3
   PubMedGoogle Scholar
• Anonymous. Reports of societies: Oxygen therapy. A discus-sion on the therapeutic uses of oxygen, January 20th, 1920 in the Section of Therapeutics and Pharmacology of the Royal Society of Medicine, including comments by J. Barcroft and J.S. Haldane. Br Med J1920
   Google Scholar
• Haldane JS. Respiration. New Haven, CT: Yale University Press, 1922
   Google Scholar
• Henderson. Resuscitation from asphyxia. J Am Med Assoc 1928;90:583
   Google Scholar
• Eastman. Asphyxia neonatorum. Int Clin 1936;2:274
   Google Scholar
• Hess JH, Lundeen EC. The Premature Infant: Medical and Nursing Care. Philadelphia: Lippincott, 1949
   Google Scholar
• Apgar V. A proposal for a new method of evaluation of the newborn infant. Anesth Analg 1953;32:260
   Google Scholar
• Adamsons K, Behrman R, Dawes GS, et al. Resuscitation by positive pressure ventilation and Tris-hydroxy-methylaminomethane of rhesus monkeys asphyxiatedatbirth. J Pediatr 1964;65:807–18
   PubMed Web of Science ®Google Scholar
• Behrman R, James L, Klaus M, et al. Treatment of the asphyxiated newborn infant: current opinions and practices as expressed by a panel. J Pediatr 1969;74:981–8
   PubMed Web of Science ®Google Scholar
• Silverman W. Retrolental fibroplasia. In Dunham's Premature Infants, 3rd edn. New York: Harper & Row, 1961:259–73
   Google Scholar
• Omer M, Robson E, Neligan G. Can initial resuscitation of preterm babies reduce the death rate from hyaline membrane disease?Arch Dis Child 1974;49:219–21
   Google Scholar
• Fox WW, Gutsche BB, DeVore JS. A delivery room approach to the meconium aspiration syndrome (MAS). Clin Pediatr 1977;16:325–8
   Google Scholar
• Walsh SZ, Lind J. The fetal circulation and its alteration at birth. In Stave U, ed. Perinatal Physiology. New York: Plenum Medical Book Company, 1970:129–80
   Google Scholar
• Klaus M, Meyer BP. Oxygen therapy for the newborn. Pediatr Clin North Am 1966;13:731–52
   PubMed Web of Science ®Google Scholar
• Emergency Cardiac Care Committee and Subcommittees AHA. Standards for CPR and ECC. Part V. Advanced cardiac life support for neonates. J Am Med Assoc 1980;244:495–500
   Google Scholar
• Oxer HF. Simply add oxygen: Why isn't oxygen administra-tion taught in all resuscitation training? Resuscitation 2000;43:163–9
   PubMed Web of Science ®Google Scholar
• Saugstad O. Resuscitation of newborn infants with room air oroxygen. Semin Neonatol2001;6:233–9
   PubMedGoogle Scholar
• Ramji S, Thirupuram AS, Rootwelt T, et al. Resuscitation of asphyxic newborn infants with room air or 100% oxygen. Pediatr Res 1993;34:809–12
   PubMed Web of Science ®Google Scholar
• Vento M, Asensi M, Sastre J, et al. Resuscitation with room air instead of 100% oxygen prevents oxidative stress in moderately asphyxiated term neonates. Pediatrics 2001;107: 642–7
   PubMed Web of Science ®Google Scholar
• Vento M, Asensi M, Sastre J, et al. Six years of experience with the use of room air for the resuscitation of asphyxiated newly born term infants. Biol Neonate 2001;79:261–7
   PubMedGoogle Scholar
• Vento M, Asensi M, Sastre J, et al. Hyperoxemia caused by resuscitation with pure oxygen may alter intracellular redox status by increasing oxidised glutathione in asphyxiated newly born infants. Semin Perinatol 2002;26:406–10
   PubMed Web of Science ®Google Scholar
• Vento M, Sastre J, Asensi M, et al. Oxidative stress in asphyxiated term infants resuscitated with 100% oxygen. J Pediatr 2003;142:242–8
   Web of Science ®Google Scholar
• Ramji S, Rasaily R, Mishra P. etal. Resuscitation of asphyxi-ated newborns with room air or 100% oxygen at birth: a multicentric clinical trial. Ind Pediatr 2003;40: 510
   Google Scholar
• Vento M, Garcia-Sala F, Vifia J, etal. Asphyxiated neonates resuscitation with room air (RAR) vs oxygen. Pediatr Res 1999;45:890 (abstr)
   Google Scholar
• Garcia de la Asunción J, Milian A, Pla R, etal. Mitochondrial glutathione oxidation correlates with age-associated oxidative damage to mitochondrial DNA. FASEB J 1996;10:333–8
   Google Scholar
• Garcia de la Asunción J, Del Olmo M, Sastre J, etal. AZT treatment induces molecular and ultrastructural oxidative damage to muscle mitochondria — prevention by antioxidant vitamins. J Clin Invest 1998;101:1–6
   PubMedGoogle Scholar
• Neefies V. Evelo C, Mars L, et al. Erythrocyte glutathione S transferase as a marker of oxidative stress at birth. Arch Dis Child Fetal Neonatal Ed 1999;81:F130–3
   PubMed Web of Science ®Google Scholar
• Frank L, Groseclose E. Preparation for birth into an 02-rich environment: the antioxidant enzymes in the developing rabbit lung. Pediatr Res 1984;18:240–4
   PubMed Web of Science ®Google Scholar
• Schafer FQ, Buettner GR. Redox environment of the cell as viewed through the redox state of the glutathione disulfide/ glutathione couple. Free Radic Biol Med 2001;30:1191–212
   PubMed Web of Science ®Google Scholar
• Suzuki Y, Forman H, Sevanian A. Oxidants as stimulators of signal transduction. Free Radic Biol Med 1997;22: 269–85
   PubMed Web of Science ®Google Scholar
• Nakamura H, Makamura K, Yodoi J. Redox regulation of cellular activation. Ann Rev Immunol 1997;15:351–69
   PubMed Web of Science ®Google Scholar
• Emergency Cardiac Care Committee and Subcommittees AHA. Guidelines for cardiopulmonary resuscitation and emergency cardiac care: VIII. Neonatal resuscitation. J Am Med Assoc 1992;268:2276–81
   PubMed Web of Science ®Google Scholar
• Anonymous. Part 1: Introduction to the international guidelines 2000 for CPR and ECC. A consensus on science. Resuscitation 2000;46:3–15
   PubMedGoogle Scholar
• Emergency Cardiovascular Care Committee and Sub-committees AHA. International Guidelines for Neonatal Resuscitation: an excerpt from the Guidelines 2000 for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care: International Consensus on Science. Pediatrics 2000;106:e29
   PubMed Web of Science ®Google Scholar
• Saugstad O, Ramji S, Irani S, etal. Resuscitation of newborn infants with 2 1% or 100% oxygen: follow-up at 18 to 24 months. Pediatrics 2003;112:296–300
   PubMed Web of Science ®Google Scholar
• Clerici G, Luzietti R, DiRenzo GC. Monitoring of antepartum and intrapartum fetal hypoxemia: pathophysiological basis and available techniques. Biol Neonate 2001;79:246–53
   Google Scholar
• Weinberger B, Carbone T, England S, et al. Effects of perinatal hypoxia on serum unbound free fatty acids and lung inflammatory mediators. Biol Neonate 2001;79:61–6
   PubMedGoogle Scholar
• Theophilopoulos DT, Burchfield DJ. Accuracy of different methods for heart rate determination during simulated neonatal resuscitations. J Perinatol 1998;18:65–7
   PubMedGoogle Scholar