Maternal serum concentrations of the chemokine CXCL10/IP-10 are elevated in acute pyelonephritis during pregnancy

References

• Pitukkijronnakorn S, Chittacharoen A, Herabutya Y. Maternal and perinatal outcomes in pregnancy with acute pyelonephritis. Int J Gynaecol Obstet 2005; 89: 286–287
   PubMed Web of Science ®Google Scholar
• Wing D A. Pyelonephritis in pregnancy: Treatment options for optimal outcomes. Drugs 2001; 61: 2087–2096
   PubMed Web of Science ®Google Scholar
• Hill J B, Sheffield J S, McIntire D D, Wendel G D, Jr. Acute pyelonephritis in pregnancy. Obstet Gynecol 2005; 105: 18–23
   PubMed Web of Science ®Google Scholar
• Cox S M, Shelburne P, Mason R, Guss S, Cunningham F G. Mechanisms of hemolysis and anemia associated with acute antepartum pyelonephritis. Am J Obstet Gynecol 1991; 164: 587–590
   PubMed Web of Science ®Google Scholar
• Cavenee M R, Cox S M, Mason R, Cunningham F G. Erythropoietin in pregnancies complicated by pyelonephritis. Obstet Gynecol 1994; 84: 252–254
   PubMed Web of Science ®Google Scholar
• Gilstrap L C, Leveno K J, Cunningham F G, Whalley P J, Roark M L. Renal infection and pregnancy outcome. Am J Obstet Gynecol 1981; 141: 709–716
   PubMed Web of Science ®Google Scholar
• Cunningham F G, Lucas M J. Urinary tract infections complicating pregnancy. Baillieres Clin Obstet Gynaecol 1994; 8: 353–373
   PubMed Web of Science ®Google Scholar
• Cavanagh D, Rao P S. Septic shock (endotoxic shock). Clin Obstet Gynecol 1973; 16: 25–39
   PubMedGoogle Scholar
• Dilworth E E, Ward J V. Bacteremic shock in pyelonephritis and criminal abortion. Obstet Gynecol 1961; 17: 160–167
   PubMed Web of Science ®Google Scholar
• Cavanagh D, Knuppel R A, Shepherd J H, Anderson R, Rao P S. Septic shock and the obstetrician/gynecologist. South Med J 1982; 75: 809–813
   PubMed Web of Science ®Google Scholar
• Mabie W C, Barton J R, Sibai B. Septic shock in pregnancy. Obstet Gynecol 1997; 90: 553–561
   PubMed Web of Science ®Google Scholar
• Cunningham F G, Leveno K J, Hankins G D, Whalley P J. Respiratory insufficiency associated with pyelonephritis during pregnancy. Obstet Gynecol 1984; 63: 121–125
   PubMed Web of Science ®Google Scholar
• Catanzarite V A, Willms D. Adult respiratory distress syndrome in pregnancy: Report of three cases and review of the literature. Obstet Gynecol Surv 1997; 52: 381–392
   PubMedGoogle Scholar
• Cunningham F G, Lucas M J, Hankins G D. Pulmonary injury complicating antepartum pyelonephritis. Am J Obstet Gynecol 1987; 156: 797–807
   PubMed Web of Science ®Google Scholar
• Neville L F, Mathiak G, Bagasra O. The immunobiology of interferon-gamma inducible protein 10 kD (IP-10): A novel, pleiotropic member of the C–X–C chemokine superfamily. Cytokine Growth Factor Rev 1997; 8: 207–219
   PubMedGoogle Scholar
• Strieter R M, Polverini P J, Kunkel S L, Arenberg D A, Burdick M D, Kasper J, Dzuiba J, Van Damme J, Walz A, Marriott D, et al. The functional role of the ELR motif in CXC chemokine-mediated angiogenesis. J Biol Chem 1995; 270: 27 348–27 357
   Web of Science ®Google Scholar
• Strieter R M, Polverini P J, Arenberg D A, Kunkel S L. The role of CXC chemokines as regulators of angiogenesis. Shock 1995; 4: 155–160
   PubMed Web of Science ®Google Scholar
• Strieter R M, Polverini P J, Arenberg D A, Walz A, Opdenakker G, Van D, J, Kunkel S L. Role of C–X–C chemokines as regulators of angiogenesis in lung cancer. J Leukoc Biol 1995; 57: 752–762
   PubMed Web of Science ®Google Scholar
• Rollins B J. Chemokines. Blood 1997; 90: 909–928
   PubMed Web of Science ®Google Scholar
• Luster A D. Chemokines—chemotactic cytokines that mediate inflammation. N Engl J Med 1998; 338: 436–445
   PubMed Web of Science ®Google Scholar
• Belperio J A, Keane M P, Arenberg D A, Addison C L, Ehlert J E, Burdick M D, Strieter R M. CXC chemokines in angiogenesis. J Leukoc Biol 2000; 68: 1–8
   PubMed Web of Science ®Google Scholar
• Rossi D, Zlotnik A. The biology of chemokines and their receptors. Annu Rev Immunol 2000; 11: 217–242
   Google Scholar
• Bernardini G, Ribatti D, Spinetti G, Morbidelli L, Ziche M, Santoni A, Capogrossi M C, Napolitano M. Analysis of the role of chemokines in angiogenesis. J Immunol Methods 2003; 273: 83–101
   PubMed Web of Science ®Google Scholar
• Rosenkilde M M, Schwartz T W. The chemokine system—a major regulator of angiogenesis in health and disease. APMIS 2004; 112: 481–495
   PubMed Web of Science ®Google Scholar
• Romagnani P, Lasagni L, Annunziato F, Serio M, Romagnani S. CXC chemokines: The regulatory link between inflammation and angiogenesis. Trends Immunol 2004; 25: 201–209
   PubMed Web of Science ®Google Scholar
• Strieter R M, Burdick M D, Gomperts B N, Belperio J A, Keane M P. CXC chemokines in angiogenesis. Cytokine Growth Factor Rev 2005; 16: 593–609
   PubMed Web of Science ®Google Scholar
• Charo I F, Ransohoff R M. The many roles of chemokines and chemokine receptors in inflammation. N Engl J Med 2006; 354: 610–621
   PubMed Web of Science ®Google Scholar
• Luster A D, Unkeless J C, Ravetch J V. Gamma-interferon transcriptionally regulates an early-response gene containing homology to platelet proteins. Nature 1985; 315: 672–676
   PubMed Web of Science ®Google Scholar
• Luster A D, Ravetch J V. Biochemical characterization of a gamma interferon-inducible cytokine (IP-10). J Exp Med 1987; 166: 1084–1097
   PubMed Web of Science ®Google Scholar
• Luster A D, Ravetch J V. Genomic characterization of a gamma-interferon-inducible gene (IP-10) and identification of an interferon-inducible hypersensitive site. Mol Cell Biol 1987; 7: 3723–3731
   PubMed Web of Science ®Google Scholar
• Kaplan G, Luster A D, Hancock G, Cohn Z A. The expression of a gamma interferon-induced protein (IP-10) in delayed immune responses in human skin. J Exp Med 1987; 166: 1098–1108
   PubMed Web of Science ®Google Scholar
• Gottlieb A B, Luster A D, Posnett D N, Carter D M. Detection of a gamma interferon-induced protein IP-10 in psoriatic plaques. J Exp Med 1988; 168: 941–948
   PubMed Web of Science ®Google Scholar
• Vanguri P, Farber J M. IFN and virus-inducible expression of an immediate early gene, crg-2/IP-10, and a delayed gene, I-A alpha in astrocytes and microglia. J Immunol 1994; 152: 1411–1418
   PubMed Web of Science ®Google Scholar
• Sarris A H, Esgleyes-Ribot T, Crow M, Broxmeyer H E, Karasavvas N, Pugh W, Grossman D, Deisseroth A, Duvic M. Cytokine loops involving interferon-gamma and IP-10, a cytokine chemotactic for CD4+ lymphocytes: An explanation for the epidermotropism of cutaneous T-cell lymphoma?. Blood 1995; 86: 651–658
   PubMed Web of Science ®Google Scholar
• Vanguri P. Interferon-gamma-inducible genes in primary glial cells of the central nervous system: Comparisons of astrocytes with microglia and Lewis with brown Norway rats. J Neuroimmunol 1995; 56: 35–43
   PubMed Web of Science ®Google Scholar
• Cassatella M A, Gasperini S, Calzetti F, Bertagnin A, Luster A D, McDonald P P. Regulated production of the interferon-gamma-inducible protein-10 (IP-10) chemokine by human neutrophils. Eur J Immunol 1997; 27: 111–115
   PubMed Web of Science ®Google Scholar
• Gasperini S, Marchi M, Calzetti F, Laudanna C, Vicentini L, Olsen H, Murphy M, Liao F, Farber J, Cassatella M A. Gene expression and production of the monokine induced by IFN-gamma (MIG), IFN-inducible T cell alpha chemoattractant (I-TAC), and IFN-gamma-inducible protein-10 (IP-10) chemokines by human neutrophils. J Immunol 1999; 162: 4928–4937
   PubMed Web of Science ®Google Scholar
• Frigerio S, Junt T, Lu B, Gerard C, Zumsteg U, Hollander G A, Piali L. Beta cells are responsible for CXCR3-mediated T-cell infiltration in insulitis. Nat Med 2002; 8: 1414–1420
   PubMed Web of Science ®Google Scholar
• Cardozo A K, Proost P, Gysemans C, Chen M C, Mathieu C, Eizirik D L. IL-1beta and IFN-gamma induce the expression of diverse chemokines and IL-15 in human and rat pancreatic islet cells, and in islets from pre-diabetic NOD mice. Diabetologia 2003; 46: 255–266
   PubMed Web of Science ®Google Scholar
• Narumi S, Yoneyama H, Inadera H, Nishioji K, Itoh Y, Okanoue T, Matsushima K. TNF-alpha is a potent inducer for IFN-inducible protein-10 in hepatocytes and unaffected by GM-CSF in vivo, in contrast to IL-1beta and IFN-gamma. Cytokine 2000; 12: 1007–1016
   PubMed Web of Science ®Google Scholar
• Kraft M, Riedel S, Maaser C, Kucharzik T, Steinbuechel A, Domschke W, Luegering N. IFN-gamma synergizes with TNF-alpha but not with viable H. pylori in up-regulating CXC chemokine secretion in gastric epithelial cells. Clin Exp Immunol 2001; 126: 474–481
   PubMed Web of Science ®Google Scholar
• Algood H M, Lin P L, Yankura D, Jones A, Chan J, Flynn J L. TNF influences chemokine expression of macrophages in vitro and that of CD11b+ cells in vivo during Mycobacterium tuberculosis infection. J Immunol 2004; 172: 6846–6857
   PubMed Web of Science ®Google Scholar
• Villagomez M T, Bae S J, Ogawa I, Takenaka M, Katayama I. Tumour necrosis factor-alpha but not interferon-gamma is the main inducer of inducible protein-10 in skin fibroblasts from patients with atopic dermatitis. Br J Dermatol 2004; 150: 910–916
   PubMed Web of Science ®Google Scholar
• Hardaker E L, Bacon A M, Carlson K, Roshak A K, Foley J J, Schmidt D B, Buckley P T, Comegys M, Panettieri R A, Jr, Sarau H M, et al. Regulation of TNF-alpha- and IFN-gamma-induced CXCL10 expression: Participation of the airway smooth muscle in the pulmonary inflammatory response in chronic obstructive pulmonary disease. FASEB J 2004; 18: 191–193
   PubMed Web of Science ®Google Scholar
• Sheng W S, Hu S, Ni H T, Rowen T N, Lokensgard J R, Peterson P K. TNF-alpha-induced chemokine production and apoptosis in human neural precursor cells. J Leukoc Biol 2005; 78: 1233–1241
   PubMed Web of Science ®Google Scholar
• Berthier-Vergnes O, Bermond F, Flacher V, Massacrier C, Schmitt D, Peguet-Navarro J. TNF-alpha enhances phenotypic and functional maturation of human epidermal Langerhans cells and induces IL-12 p40 and IP-10/CXCL-10 production. FEBS Lett 2005; 579: 3660–3668
   PubMed Web of Science ®Google Scholar
• Shin H S, Drysdale B E, Shin M L, Noble P W, Fisher S N, Paznekas W A. Definition of a lipopolysaccharide-responsive element in the 5′-flanking regions of MuRantes and crg-2. Mol Cell Biol 1994; 14: 2914–2925
   PubMed Web of Science ®Google Scholar
• Nazar A S, Cheng G, Shin H S, Brothers P N, Dhib-Jalbut S, Shin M L, Vanguri P. Induction of IP-10 chemokine promoter by measles virus: Comparison with interferon-gamma shows the use of the same response element but with differential DNA–protein binding profiles. J Neuroimmunol 1997; 77: 116–127
   PubMed Web of Science ®Google Scholar
• Cheng G, Nazar A S, Shin H S, Vanguri P, Shin M L. IP-10 gene transcription by virus in astrocytes requires cooperation of ISRE with adjacent kappaB site but not IRF-1 or viral transcription. J Interferon Cytokine Res 1998; 18: 987–997
   PubMed Web of Science ®Google Scholar
• Gasper N A, Petty C C, Schrum L W, Marriott I, Bost K L. Bacterium-induced CXCL10 secretion by osteoblasts can be mediated in part through toll-like receptor 4. Infect Immun 2002; 70: 4075–4082
   PubMed Web of Science ®Google Scholar
• Shen Q, Zhang R, Bhat N R. MAP kinase regulation of IP10/CXCL10 chemokine gene expression in microglial cells. Brain Res 2006; 1086: 9–16
   PubMed Web of Science ®Google Scholar
• Durand S H, Flacher V, Romeas A, Carrouel F, Colomb E, Vincent C, Magloire H, Couble M L, Bleicher F, Staquet M J, et al. Lipoteichoic acid increases TLR and functional chemokine expression while reducing dentin formation in in vitro differentiated human odontoblasts. J Immunol 2006; 176: 2880–2887
   PubMed Web of Science ®Google Scholar
• Ohmori Y, Hamilton T A. Cooperative interaction between interferon (IFN) stimulus response element and kappa B sequence motifs controls IFN gamma- and lipopolysaccharide-stimulated transcription from the murine IP-10 promoter. J Biol Chem 1993; 268: 6677–6688
   PubMed Web of Science ®Google Scholar
• Ohmori Y, Hamilton T A. The interferon-stimulated response element and a kappa B site mediate synergistic induction of murine IP-10 gene transcription by IFN-gamma and TNF-alpha. J Immunol 1995; 154: 5235–5244
   PubMed Web of Science ®Google Scholar
• Osawa Y, Iho S, Takauji R, Takatsuka H, Yamamoto S, Takahashi T, Horiguchi S, Urasaki Y, Matsuki T, Fujieda S. Collaborative action of NF-kappaB and p38 MAPK is involved in CpG DNA-induced IFN-alpha and chemokine production in human plasmacytoid dendritic cells. J Immunol 2006; 177: 4841–4852
   PubMed Web of Science ®Google Scholar
• Park C, Lee S, Cho I H, Lee H K, Kim D, Choi S Y, Oh S B, Park K, Kim J S, Lee S J. TLR3-mediated signal induces proinflammatory cytokine and chemokine gene expression in astrocytes: Differential signaling mechanisms of TLR3-induced IP-10 and IL-8 gene expression. Glia 2006; 53: 248–256
   PubMed Web of Science ®Google Scholar
• Gangur V, Simons F E, Hayglass K T. Human IP-10 selectively promotes dominance of polyclonally activated and environmental antigen-driven IFN-gamma over IL-4 responses. FASEB J 1998; 12: 705–713
   PubMed Web of Science ®Google Scholar
• Sallusto F, Lenig D, Mackay C R, Lanzavecchia A. Flexible programs of chemokine receptor expression on human polarized T helper 1 and 2 lymphocytes. J Exp Med 1998; 187: 875–883
   PubMed Web of Science ®Google Scholar
• Yamamoto J, Adachi Y, Onoue Y, Adachi Y S, Okabe Y, Itazawa T, Toyoda M, Seki T, Morohashi M, Matsushima K, et al. Differential expression of the chemokine receptors by the Th1- and Th2-type effector populations within circulating CD4+ T cells. J Leukoc Biol 2000; 68: 568–574
   PubMed Web of Science ®Google Scholar
• Alexander G R, Himes J H, Kaufman R B, Mor J, Kogan M. A United States national reference for fetal growth. Obstet Gynecol 1996; 87: 163–168
   PubMed Web of Science ®Google Scholar
• Baggiolini M, Dewald B, Moser B. Human chemokines: An update. Annu Rev Immunol 1997; 15: 675–705
   PubMed Web of Science ®Google Scholar
• Sallusto F, Mackay C R, Lanzavecchia A. The role of chemokine receptors in primary, effector, and memory immune responses. Annu Rev Immunol 2000; 18: 593–620
   PubMed Web of Science ®Google Scholar
• Baggiolini M. Chemokines in pathology and medicine. J Intern Med 2001; 250: 91–104
   PubMed Web of Science ®Google Scholar
• Keane M P, Arenberg D A, Lynch J P, III, Whyte R I, Iannettoni M D, Burdick M D, Wilke C A, Morris S B, Glass M C, DiGiovine B, et al. The CXC chemokines, IL-8 and IP-10, regulate angiogenic activity in idiopathic pulmonary fibrosis. J Immunol 1997; 159: 1437–1443
   PubMed Web of Science ®Google Scholar
• Strieter R M, Belperio J A, Keane M P. CXC chemokines in angiogenesis related to pulmonary fibrosis. Chest 2002; 122: 298S–301S
   PubMed Web of Science ®Google Scholar
• Loetscher M, Gerber B, Loetscher P, Jones S A, Piali L, Clark-Lewis I, Baggiolini M, Moser B. Chemokine receptor specific for IP10 and mig: Structure, function, and expression in activated T-lymphocytes. J Exp Med 1996; 184: 963–969
   PubMed Web of Science ®Google Scholar
• Liu L, Callahan M K, Huang D, Ransohoff R M. Chemokine receptor CXCR3: An unexpected enigma. Curr Top Dev Biol 2005; 68: 149–181
   PubMed Web of Science ®Google Scholar
• Cole K E, Strick C A, Paradis T J, Ogborne K T, Loetscher M, Gladue R P, Lin W, Boyd J G, Moser B, Wood D E, et al. Interferon-inducible T cell alpha chemoattractant (I-TAC): A novel non-ELR CXC chemokine with potent activity on activated T cells through selective high affinity binding to CXCR3. J Exp Med 1998; 187: 2009–2021
   PubMed Web of Science ®Google Scholar
• Cox M A, Jenh C H, Gonsiorek W, Fine J, Narula S K, Zavodny P J, Hipkin R W. Human interferon-inducible 10-kDa protein and human interferon-inducible T cell alpha chemoattractant are allotopic ligands for human CXCR3: Differential binding to receptor states. Mol Pharmacol 2001; 59: 707–715
   PubMed Web of Science ®Google Scholar
• Sauty A, Colvin R A, Wagner L, Rochat S, Spertini F, Luster A D. CXCR3 internalization following T cell-endothelial cell contact: Preferential role of IFN-inducible T cell alpha chemoattractant (CXCL11). J Immunol 2001; 167: 7084–7093
   PubMed Web of Science ®Google Scholar
• Colvin R A, Campanella G S, Sun J, Luster A D. Intracellular domains of CXCR3 that mediate CXCL9, CXCL10, and CXCL11 function. J Biol Chem 2004; 279: 30 219–30 227
   Web of Science ®Google Scholar
• Dajotoy T, Andersson P, Bjartell A, Lofdahl C G, Tapper H, Egesten A. Human eosinophils produce the T cell-attracting chemokines MIG and IP-10 upon stimulation with IFN-gamma. J Leukoc Biol 2004; 76: 685–691
   PubMed Web of Science ®Google Scholar
• Godaly G, Otto G, Burdick M D, Strieter R M, Svanborg C. Fimbrial lectins influence the chemokine repertoire in the urinary tract mucosa. Kidney Int 2007; 71: 778–786
   PubMed Web of Science ®Google Scholar
• Hoffmann A, Levchenko A, Scott M L, Baltimore D. The IkappaB–NF-kappaB signaling module: Temporal control and selective gene activation. Science 2002; 298: 1241–1245
   PubMed Web of Science ®Google Scholar
• Taub D D, Lloyd A R, Conlon K, Wang J M, Ortaldo J R, Harada A, Matsushima K, Kelvin D J, Oppenheim J J. Recombinant human interferon-inducible protein 10 is a chemoattractant for human monocytes and T lymphocytes and promotes T cell adhesion to endothelial cells. J Exp Med 1993; 177: 1809–1814
   PubMed Web of Science ®Google Scholar
• Taub D D, Sayers T J, Carter C R, Ortaldo J R. Alpha and beta chemokines induce NK cell migration and enhance NK-mediated cytolysis. J Immunol 1995; 155: 3877–3888
   PubMed Web of Science ®Google Scholar
• Dewald B, Moser B, Barella L, Schumacher C, Baggiolini M, Clark-Lewis I. IP-10, a gamma-interferon-inducible protein related to interleukin-8, lacks neutrophil activating properties. Immunol Lett 1992; 32: 81–84
   PubMed Web of Science ®Google Scholar
• Qin S, Rottman J B, Myers P, Kassam N, Weinblatt M, Loetscher M, Koch A E, Moser B, Mackay C R. The chemokine receptors CXCR3 and CCR5 mark subsets of T cells associated with certain inflammatory reactions. J Clin Invest 1998; 101: 746–754
   PubMed Web of Science ®Google Scholar
• Muehlinghaus G, Cigliano L, Huehn S, Peddinghaus A, Leyendeckers H, Hauser A E, Hiepe F, Radbruch A, Arce S, Manz R A. Regulation of CXCR3 and CXCR4 expression during terminal differentiation of memory B cells into plasma cells. Blood 2005; 105: 3965–3971
   PubMed Web of Science ®Google Scholar
• Fotopoulos S, Mouchtouri A, Xanthou G, Lipsou N, Petrakou E, Xanthou M. Inflammatory chemokine expression in the peripheral blood of neonates with perinatal asphyxia and perinatal or nosocomial infections. Acta Paediatr 2005; 94: 800–806
   PubMed Web of Science ®Google Scholar
• Ng P C, Li K, Chui K M, Leung T F, Wong R P, Chu W C, Wong E, Fok T F. IP-10 is an early diagnostic marker for identification of late-onset bacterial infection in preterm infants. Pediatr Res 2007; 61: 93–98
   PubMed Web of Science ®Google Scholar
• Azzurri A, Sow O Y, Amedei A, Bah B, Diallo S, Peri G, Benagiano M, D'Elios M M, Mantovani A, Del Prete, G. IFN-gamma-inducible protein 10 and pentraxin 3 plasma levels are tools for monitoring inflammation and disease activity in Mycobacterium tuberculosis infection. Microbes Infect 2005; 7: 1–8
   PubMed Web of Science ®Google Scholar
• Puneet P, Moochhala S, Bhatia M. Chemokines in acute respiratory distress syndrome. Am J Physiol Lung Cell Mol Physiol 2005; 288: L3–15
   PubMed Web of Science ®Google Scholar
• Strieter R M, Kunkel S L. Acute lung injury: The role of cytokines in the elicitation of neutrophils. J Investig Med 1994; 42: 640–651
   PubMed Web of Science ®Google Scholar
• Chien J Y, Hsueh P R, Cheng W C, Yu C J, Yang P C. Temporal changes in cytokine/chemokine profiles and pulmonary involvement in severe acute respiratory syndrome. Respirology 2006; 11: 715–722
   PubMed Web of Science ®Google Scholar
• Olszyna D P, Prins J M, Dekkers P E, De Jonge, E, Speelman P, Van Deventer S J, Van Der Poll, T. Sequential measurements of chemokines in urosepsis and experimental endotoxemia. J Clin Immunol 1999; 19: 399–405
   PubMed Web of Science ®Google Scholar
• Otto G, Burdick M, Strieter R, Godaly G. Chemokine response to febrile urinary tract infection. Kidney Int 2005; 68: 62–70
   PubMed Web of Science ®Google Scholar
• Gotsch F, Romero R, Friel L, Kusanovic J P, Espinoza J, Erez O, Than N G, Mittal P, Edwin S, Yoon B H. Cxcl10/Ip-10: A missing link between inflammation and Anti-Angiogenesis in preeclampsia?. Matern Fetal Med 2007, 167
   Google Scholar
• Cole A M, Ganz T, Liese A M, Burdick M D, Liu L, Strieter R M. Cutting edge: IFN-inducible ELR-CXC chemokines display defensin-like antimicrobial activity. J Immunol 2001; 167: 623–627
   PubMed Web of Science ®Google Scholar
• Godaly G, Bergsten G, Hang L, Fischer H, Frendeus B, Lundstedt A C, Samuelsson M, Samuelsson P, Svanborg C. Neutrophil recruitment, chemokine receptors, and resistance to mucosal infection. J Leukoc Biol 2001; 69: 899–906
   PubMed Web of Science ®Google Scholar
• Hang L, Haraoka M, Agace W W, Leffler H, Burdick M, Strieter R, Svanborg C. Macrophage inflammatory protein-2 is required for neutrophil passage across the epithelial barrier of the infected urinary tract. J Immunol 1999; 162: 3037–3044
   PubMed Web of Science ®Google Scholar
• Olszyna D P, Florquin S, Sewnath M, Branger J, Speelman P, Van Deventer S J, Strieter R M, Van Der Poll T. CXC chemokine receptor 2 contributes to host defense in murine urinary tract infection. J Infect Dis 2001; 184: 301–307
   PubMed Web of Science ®Google Scholar
• Frendeus B, Godaly G, Hang L, Karpman D, Lundstedt A C, Svanborg C. Interleukin 8 receptor deficiency confers susceptibility to acute experimental pyelonephritis and may have a human counterpart. J Exp Med 2000; 192: 881–890
   PubMed Web of Science ®Google Scholar
• Godaly G, Hang L, Frendeus B, Svanborg C. Transepithelial neutrophil migration is CXCR1 dependent in vitro and is defective in IL-8 receptor knockout mice. J Immunol 2000; 165: 5287–5294
   PubMed Web of Science ®Google Scholar
• Luo Y, Chen X, O'donnell M A. Mycobacterium bovis bacillus Calmette–Guerin (BCG) induces human CC- and CXC-chemokines in vitro and in vivo. Clin Exp Immunol 2007; 147: 370–378
   PubMed Web of Science ®Google Scholar
• Poppas D P, Pavlovich C P, Folkman J, Voest E E, Chen X, Luster A D, O'donnell M A. Intravesical bacille Calmette–Guerin induces the antiangiogenic chemokine interferon-inducible protein 10. Urology 1998; 52: 268–275
   PubMed Web of Science ®Google Scholar
• Zeng X, Moore T A, Newstead M W, Deng J C, Kunkel S L, Luster A D, Standiford T J. Interferon-inducible protein 10, but not monokine induced by gamma interferon, promotes protective type 1 immunity in murine Klebsiella pneumoniae pneumonia. Infect Immun 2005; 73: 8226–8236
   PubMed Web of Science ®Google Scholar
• Yoshio H, Lagercrantz H, Gudmundsson G H, Agerberth B. First line of defense in early human life. Semin Perinatol 2004; 28: 304–311
   PubMed Web of Science ®Google Scholar
• Espinoza J, Chaiworapongsa T, Romero R, Edwin S, Rathnasabapathy C, Gomez R, Bujold E, Camacho N, Kim Y M, Hassan S, et al. Antimicrobial peptides in amniotic fluid: Defensins, calprotectin and bacterial/permeability-increasing protein in patients with microbial invasion of the amniotic cavity, intra-amniotic inflammation, preterm labor and premature rupture of membranes. J Matern Fetal Neonatal Med 2003; 13: 2–21
   PubMedGoogle Scholar
• Svinarich D M, Gomez R, Romero R. Detection of human defensins in the placenta. Am J Reprod Immunol 1997; 38: 252–255
   PubMed Web of Science ®Google Scholar
• Svinarich D M, Wolf N A, Gomez R, Gonik B, Romero R. Detection of human defensin 5 in reproductive tissues. Am J Obstet Gynecol 1997; 176: 470–475
   PubMed Web of Science ®Google Scholar
• Cole A M, Ganz T. Human antimicrobial peptides: Analysis and application. Biotechniques 2000; 29: 822–826, 828,830–831
   PubMed Web of Science ®Google Scholar
• Papagianni M. Ribosomally synthesized peptides with antimicrobial properties: Biosynthesis, structure, function, and applications. Biotechnol Adv 2003; 21: 465–499
   PubMed Web of Science ®Google Scholar
• Gallo R L, Murakami M, Ohtake T, Zaiou M. Biology and clinical relevance of naturally occurring antimicrobial peptides. J Allergy Clin Immunol 2002; 110: 823–831
   PubMed Web of Science ®Google Scholar
• Chen H, Xu Z, Peng L, Fang X, Yin X, Xu N, Cen P. Recent advances in the research and development of human defensins. Peptides 2006; 27: 931–940
   PubMed Web of Science ®Google Scholar
• Territo M C, Ganz T, Selsted M E, Lehrer R. Monocyte-chemotactic activity of defensins from human neutrophils. J Clin Invest 1989; 84: 2017–2020
   PubMed Web of Science ®Google Scholar
• Yang D, Chen Q, Chertov O, Oppenheim J J. Human neutrophil defensins selectively chemoattract naive T and immature dendritic cells. J Leukoc Biol 2000; 68: 9–14
   PubMed Web of Science ®Google Scholar
• Chertov O, Michiel D F, Xu L, Wang J M, Tani K, Murphy W J, Longo D L, Taub D D, Oppenheim J J. Identification of defensin-1, defensin-2, and CAP37/azurocidin as T-cell chemoattractant proteins released from interleukin-8-stimulated neutrophils. J Biol Chem 1996; 271: 2935–2940
   PubMed Web of Science ®Google Scholar
• Yang D, Chertov O, Bykovskaia S N, Chen Q, Buffo M J, Shogan J, Anderson M, Schroder J M, Wang J M, Howard O M, et al. Beta-defensins: Linking innate and adaptive immunity through dendritic and T cell CCR6. Science 1999; 286: 525–528
   PubMed Web of Science ®Google Scholar
• Ganz T. Defensins and host defense. Science 1999; 286: 420–421
   PubMed Web of Science ®Google Scholar
• Elkington K W, Greb L C. Adult respiratory distress syndrome as a complication of acute pyelonephritis during pregnancy: Case report and discussion. Obstet Gynecol 1986; 67: 18S–20S
   PubMed Web of Science ®Google Scholar
• Soisson A P, Eldridge E, Kopelman J N, Duff P. Acute pyelonephritis complicated by respiratory insufficiency. A case report. J Reprod Med 1986; 31: 525–527
   PubMed Web of Science ®Google Scholar
• Towers C V, Kaminskas C M, Garite T J, Nageotte M P, Dorchester W. Pulmonary injury associated with antepartum pyelonephritis: Can patients at risk be identified?. Am J Obstet Gynecol 1991; 164: 974–978
   PubMed Web of Science ®Google Scholar
• Yazigi R, Lerner S, Tejani N. Association of acute pyelonephritis with pulmonary complications in pregnancy. A report of two cases. J Reprod Med 1990; 38: 562–564
   Google Scholar
• Pruett K, Faro S. Pyelonephritis associated with respiratory distress. Obstet Gynecol 1987; 69: 444–446
   PubMed Web of Science ®Google Scholar
• Soto E, Richani K, Romero R, Espinoza J, Chaiworapongsa T, Nien J K, Edwin S, Kim Y M, Hong J S, Goncalves L, et al. Increased concentration of the complement split product C5a in acute pyelonephritis during pregnancy. J Matern Fetal Neonatal Med 2005; 17: 247–252
   PubMed Web of Science ®Google Scholar
• Naccasha N, Gervasi M T, Chaiworapongsa T, Berman S, Yoon B H, Maymon E, Romero R. Phenotypic and metabolic characteristics of monocytes and granulocytes in normal pregnancy and maternal infection. Am J Obstet Gynecol 2001; 185: 1118–1123
   PubMed Web of Science ®Google Scholar
• Windsor A C, Mullen P G, Fowler A A, Sugerman H J. Role of the neutrophil in adult respiratory distress syndrome. Br J Surg 1993; 80: 10–17
   PubMed Web of Science ®Google Scholar
• Neumann B, Zantl N, Veihelmann A, Emmanuilidis K, Pfeffer K, Heidecke C D, Holzmann B. Mechanisms of acute inflammatory lung injury induced by abdominal sepsis. Int Immunol 1999; 11: 217–227
   PubMed Web of Science ®Google Scholar