1,018
Views
30
CrossRef citations to date
0
Altmetric
Original Article

Effects of different regimens of iron prophylaxis on maternal iron status and pregnancy outcome: a randomized control trial

, , , , &
Pages 1787-1792 | Received 24 Jun 2016, Accepted 11 Aug 2016, Published online: 02 Sep 2016

References

  • Lain KY, Catalano PM. Metabolic changes in pregnancy. Clin Obstet Gynecol 2007;50:938–48
  • World Health Organization, Food and Agriculture Organization of the United Nations. Vitamin and Mineral Requirements in Human Nutrition, 2nd ed. Geneva, World Health Organization. 2004;246–78
  • Bothwell TH. Iron requirements in pregnancy and strategies to meet them. Am J Clin Nutr 2000;72:257S–64S
  • Cetin I, Berti C, Calabrese S. Role of micronutrients in the periconceptional period. Hum Reprod Update 2010;16:80–95
  • Berti C, Decsi T, Dykes F, et al. Critical issues in setting micronutrient recommendations for pregnant women: an insight. Matern Child Nutr 2010;6:5–22
  • Milman N. Prepartum anaemia: prevention and treatment. Ann Hematol 2008;87:949–59
  • Blumfield ML, Hure AJ, Macdonald-Wicks L, et al. A systematic review and meta-analysis of micronutrient intakes during pregnancy in developed countries. Nutr Rev 2013;71:118–32
  • Pena-Rosas JP, Viteri FE. Effects and safety of preventive oral iron or iron plus folic acid supplementation for women during pregnancy. Cochrane Database Syst Rev 2009;4:CD0004736
  • Parisi F, Laoreti A, Cetin I. Multiple micronutrient needs in pregnancy in industrialized countries. Ann Nutr Metab 2014;65:13–21
  • Milman N, Bergholt T, Byg K, et al. Reference intervals for haematological variables during normal pregnancy and postpartum in 434 healthy Danish women. Eur J Haematol 2007;79:39–46
  • World Health Organization. Hemoglobin concentrations for the diagnosis of anemia and assessment of severity. Vitamin and Mineral Nutrition Information System. World Health Organization. 2011. Available from: http://www.who.int/vmnis/indicators/hemoglobin
  • Milman N. Postpartum anemia I: definition, prevalence, causes, and consequences. Ann Hematol 2011;90:1247–53
  • World Health Organization. Serum ferritin concentrations for the assessment of iron status and iron deficiency in populations. Vitamin and Mineral Nutrition Information System. World Health Organization. 2011. Available from: http://www.who.int/vmnis/indicators/ferritin/en/index.html
  • Scholl TO. Iron status during pregnancy: setting the stage for mother and infant. Am J Clin Nutr 2005;81:1218S–22S
  • Hindmarsh PC, Geary MP, Rodeck CH, et al. Effect of early maternal iron stores on placental weight and structure. Lancet 2000;356:719–23
  • Stoltzfus R, Dreyfuss M. Guidelines for the use of iron supplements to prevent and treat iron deficiency anemia. Washington, DC: ILSI Press. World Health Organization. 1998. Available from: http://www.who.int/nutrition/publications/micronutrients/guidelines_for_Iron_supplementation.pdf
  • World Health Organization. Iron and folate supplementation: standards for maternal and neonatal care. Integrated Management of Pregnancy and Childbirth (IMPAC). Department of Making Pregnancy Safer, World Health Organization. 2007. Available from: http://www.who.int/reproductivehealth/publications/maternal_perinatal_health/iron_folate_supplementation.pdf
  • Christian P, Khatry SK, Katz J, et al. Effects of alternative maternal micronutrient supplements on low birth weight in rural Nepal: double blind randomized community trial. Br Med J 2003;326:571–4
  • Zeng LX, Cheng Y, Dang SN. Impact of micronutrient supplementation during pregnancy on birth weight, duration of gestation, and perinatal mortality in rural western China: double blind cluster randomized controlled trial. Br Med J 2008;337:a2001
  • Siega-Riz AM, Hartzema AG, Turnbull C, et al. The effects of prophylactic iron given in prenatal supplements on iron status and birth outcomes: a randomized controlled trial. Am J Obstet Gynecol 2006;194:512–19
  • Brise H. Influence of meals on iron absorption in oral iron therapy. Acta Med Scand Suppl 1962;376:39–45
  • Lund EK, Wharf SG, Fairweather-Tait SJ, et al. Oral ferrous sulfate supplements increase the free radical-generating capacity of feces from healthy volunteers. Am J Clin Nutr 1999;69:250–5
  • Roberfroid D, Huybregts L, Habicht JP, et al. MISAME Study Group. Randomized controlled trial of 2 prenatal iron supplements: is there a dose-response relation with maternal hemoglobin? Am J Clin Nutr 2011;93:1012–18
  • Conrad ME, Umbreit JN, Moore EG, et al. Separate pathways for cellular uptake of ferric and ferrous iron. Am J Physiol Gastrointest Liver Physiol 2000;279:G767–74
  • Samad A, Sultana Y, Aqil M. Liposomal drug delivery systems: an update review. Curr Drug Deliv 2007;4:297–305
  • Sette S, Le Donne C, Piccinelli R, et al. INRAN-SCAI 2005-6 Study Group. The third Italian National Food Consumption Survey, INRAN-SCAI 2005-06-part 1: nutrient intakes in Italy. Nutr Metab Cardiovasc Dis 2011;21:922–32
  • LARN – Livelli di Assunzione di Riferimento di Nutrienti ed energia per la popolazione italiana Revisione. 2012. Available from: http://www.sinu.it/documenti/20121016_larn_bologna_sintesi_prefinale.pdf
  • Zaim M, Piselli L, Fioravanti P, et al. Efficacy and tolerability of a prolonged release ferrous sulphate formulation in iron deficiency anaemia: a non-inferiority controlled trial. Eur J Nutr 2012;51:221–9
  • Allen LH. Iron supplements: scientific issues concerning efficacy and implications for research and programs. J Nutr 2002;132:813S–9S
  • Peña-Rosas JP, De-Regil LM, Dowswell T, et al. Daily oral iron supplementation during pregnancy. Cochrane Database Syst Rev 2012;12:CD004736
  • Milman N, Bergholt T, Eriksen L, et al. Iron prophylaxis during pregnancy – how much iron is needed? A randomized dose–response study of 20–80 mg ferrous iron daily in pregnant women. Acta Obstet Gynecol Scand 2005;84:238–47
  • Devrim E, Tarhan I, Ergüder IB, et al. Oxidant/antioxidant status of placenta, blood, and cord blood samples from pregnant women supplemented with iron. J Soc Gynecol Investig 2006;13:502–5
  • Haider BA, Olofin I, Wang M, et al. Nutrition Impact Model Study Group (anemia): anemia, prenatal iron use, and risk of adverse pregnancy outcomes: systematic review and meta-analysis. BMJ 2013;346:f3443
  • Cogswell ME, Parvanta I, Ickes L, et al. Iron supplementation during pregnancy, anemia, and birth weight: a randomized controlled trial. Am J Clin Nutr 2003;78:773–81
  • Institute of Medicine. Iron: dietary reference intakes for vitamin A, vitamin K, arsenic, boron, chromium, copper, iodine, iron, manganese, molybdenum, nickel, silicon, vanadium, and zinc. Institute of Medicine 2001;290–393
  • Shastri L, Mishra PE, Dwarkanath P, et al. Association of oral iron supplementation with birth outcomes in non-anaemic South Indian pregnant women. Eur J Clin Nutr 2015;69:609–13
  • Milman N, Jonsson L, Dyre P, et al. Ferrous bisglycinate 25 mg iron is as effective as ferrous sulfate 50 mg iron in the prophylaxis of iron deficiency and anemia during pregnancy in a randomized trial. J Perinat Med 2014;42:197–206
  • Lassi ZS, Salam RA, Haider BA, et al. Folic acid supplementation during pregnancy for maternal health and pregnancy outcomes. Cochrane Database Syst Rev 2013;3:CD006896
  • van Uitert EM, Steegers-Theunissen RP. Influence of maternal folate status on human fetal growth parameters. Mol Nutr Food Res 2013;57:582–95
  • Hogeveen M, Blom HJ, den Heijer M. Maternal homocysteine and small-for-gestational-age offspring: systematic review and meta-analysis. Am J Clin Nutr 2012;95:130–6

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.