381
Views
10
CrossRef citations to date
0
Altmetric
Review Article

Which criteria should be used for starting pharmacologic therapy for management of gestational diabetes in pregnancy? Evidence from randomized controlled trials

ORCID Icon, ORCID Icon, , , & ORCID Icon
Pages 2905-2914 | Received 03 Jan 2018, Accepted 04 Mar 2018, Published online: 20 Mar 2018

References

  • Garner P, Okun N, Keely E, et al. A randomized controlled trial of strict glycemic control and tertiary level obstetric care versus routine obstetric care in the management of gestational diabetes: a pilot study. Am J Obstet Gynecol. 1997;177(1):190–195.
  • Langer O, Conway DL, Berkus MD, et al. A comparison of glyburide and insulin in women with gestational diabetes mellitus. N Engl J Med. 2000;343(16):1134–1138.
  • Mecacci F, Carignani L, Cioni R, et al. Maternal metabolic control and perinatal outcome in women with gestational diabetes treated with regular or lispro insulin: comparison with non-diabetic pregnant women. Eur J Obstet Gynecol Reprod Biol. 2003;111(1):19–24.
  • Schaefer-Graf UM, Kjos SL, Fauzan OH, et al. A randomized trial evaluating a predominantly fetal growth-based strategy to guide management of gestational diabetes in Caucasian women. Diabetes Care. 2004;27(2):297–302.
  • Crowther CA, Hiller JE, Moss JR, et al. Effect of treatment of gestational diabetes mellitus on pregnancy outcomes. N Engl J Med. 2005;352(24):2477–2486.
  • Anjalakshi C, Balaji V, Balaji MS, et al. A prospective study comparing insulin and glibenclamide in gestational diabetes mellitus in Asian Indian women. Diabetes Res Clin Pract. 2007;76(3):474–475.
  • Landon MB, Spong CY, Thom E, et al. A multicenter, randomized trial of treatment for mild gestational diabetes. N Engl J Med. 2009;361(14):1339–1348.
  • Ijäs H, Vääräsmäki M, Morin-Papunen L, et al. Metformin should be considered in the treatment of gestational diabetes: a prospective randomised study. BJOG. 2011;118(7):880–885.
  • Balaji V, Balaji MS, Alexander C, et al. Premixed insulin aspart 30 (BIAsp 30) versus premixed human insulin 30 (BHI 30) in gestational diabetes mellitus: a randomized open-label controlled study. Gynecol Endocrinol. 2012;28(7):529–532.
  • Mukhopadhyay P, Bag TS, Kyal A, et al. Oral Hypoglycemic Glibenclamide: can it be a substitute to insulin in the management of gestational diabetes mellitus? A Comparative Study. J South Asian Feder Obst Gynae. 2012;4(1):28–31.
  • Niromanesh S, Alavi A, Sharbaf FR, et al. Metformin compared with insulin in the management of gestational diabetes mellitus: a randomized clinical trial. Diabetes Res Clin Pract. 2012;98(3):422–429.
  • Silva JC, Pacheco C, Bizato J, et al. Metformin compared with glyburide for the management of gestational diabetes. Int J Gynecol Obstet. 2010;111(1):37–40.
  • Mesdaghinia E, Samimi M, Homaei Z, et al. Comparison of newborn outcomes in women with gestational diabetes mellitus treated with metformin or insulin: a randomised blinded trial. Int J Prev Med. 2013;4(3):327–333.
  • Spaulonci CP, Bernardes LS, Trindade TC, et al. Randomized trial of metformin vs insulin in the management of gestational diabetes. Am J Obstet Gynecol. 2013;209(1):34.e1–34.e7.
  • Behrashi M, Samimi M, Ghasemi T, et al. Comparison of glibenclamide and insulin on neonatal outcomes in pregnant women with gestational diabetes. Int J Prev Med. 2016;7:88.
  • Ainuddin J, Karim N, Hasan AA, et al. Metformin versus insulin treatment in gestational diabetes in pregnancy in a developing country: a randomized control trial. Diabetes Res Clin Pract. 2015;107(2):290–299.
  • Ainuddin JA, Karim N, Zaheer S, et al. Metformin treatment in type 2 diabetes in pregnancy: an active controlled, parallel-group, randomized, open label study in patients with type 2 diabetes in pregnancy. J Diabetes Res. 2015;2015:325851.
  • Bertini AM, Silva JC, Taborda W, et al. Perinatal outcomes and the use of oral hypoglycemic agents. J Perinat Med. 2005;33(6):519–523.
  • Beyuo T, Obed SA, Adjepong-Yamoah KK, et al. Metformin versus insulin in the management of pre-gestational diabetes mellitus in pregnancy and gestational diabetes mellitus at the Korle Bu Teaching Hospital: a randomized clinical trial. PLoS One. 2015;10(5):e0125712.
  • Buchanan TA, Kjos SL, Montoro MN, et al. Use of fetal ultrasound to select metabolic therapy for pregnancies complicated by mild gestational diabetes. Diabetes Care. 1994;17(4):275–283.
  • Casey BM, Duryea EL, Abbassi-Ghanavati M, et al. Glyburide in women with mild gestational diabetes: a randomized controlled trial. Obstet Gynecol. 2015;126(2):303–309.
  • Coustan DR, Lewis SB. Insulin therapy for gestational diabetes. Obstet Gynecol. 1978;51(3):306–310.
  • Cypryk K, Sobczak M, Pertyńska-Marczewska M, et al. Pregnancy complications and perinatal outcome in diabetic women treated with Humalog (insulin lispro) or regular human insulin during pregnancy. Med Sci Monit. 2004;10(2):29–32.
  • Di Cianni G, Volpe L, Ghio A, et al. Maternal metabolic control and perinatal outcome in women with gestational diabetes mellitus treated with lispro or aspart insulin: comparison with regular insulin. Diabetes Care. 2007;30(4):e11.
  • George A, Mathews JE, Sam D, et al. Comparison of neonatal outcomes in women with gestational diabetes with moderate hyperglycaemia on metformin or glibenclamide – a randomized controlled trial. Aust N Z J Obstet Gynaecol. 2015;55(1):47–52.
  • Hassan JA, Karim N, Sheikh Z. Metformin prevents macrosomia and neonatal morbidity in gestational diabetes. Pak J Med Sci. 2012;28(3):384–389.
  • Herrera KM, Rosenn BM, Foroutan J, et al. Randomized controlled trial of insulin detemir versus NPH for the treatment of pregnant women with diabetes. Am J Obstet Gynecol. 2015;213(3):426.e1–426.e7.
  • Hickman MA, McBride R, Boggess KA, et al. Metformin compared with insulin in the treatment of pregnant women with overt diabetes: a randomized controlled trial. Am J Perinatol. 2013;30(6):483–490.
  • Hod M, Damm P, Kaaja R, et al. Insulin Aspart Pregnancy Study Group. Fetal and perinatal outcomes in type 1 diabetes pregnancy: a randomized study comparing insulin aspart with human insulin in 322 subjects. Am J Obstet Gynecol. 2008;198(2):186.e1–186.e7.
  • Ibrahim MI, Hamdy A, Shafik A, et al. The role of adding metformin in insulin-resistant diabetic pregnant women: a randomized controlled trial. Arch Gynecol Obstet. 2014;289(5):959–965.
  • Kjos SL, Schaefer-Graf U, Sardesi S, et al. A randomized controlled trial using glycemic plus fetal ultrasound parameters versus glycemic parameters to determine insulin therapy in gestational diabetes with fasting hyperglycemia. Diabetes Care. 2001;24(11):1904–1910.
  • Moore LE, Clokey D, Rappaport VJ, et al. Metformin compared with glyburide in gestational diabetes: a randomized controlled trial. Obstet Gynecol. 2010;115(1):55–59.
  • Lain KY, Garabedian MJ, Daftary A, et al. Neonatal adiposity following maternal treatment of gestational diabetes with glyburide compared with insulin. Am J Obstet Gynecol. 2009;200(5):501.e1–501.e6.
  • Mathiesen ER, Hod M, Ivanisevic M, et al. Maternal efficacy and safety outcomes in a randomized, controlled trial comparing insulin detemir with NPH Insulin in 310 pregnant women with type 1 diabetes. Diabetes Care. 2012;35(10):2012–2017.
  • Mirzamoradi M, Heidar Z, Faalpoor Z, et al. Comparison of glyburide and insulin in women with gestational diabetes mellitus and associated perinatal outcome: a randomized clinical trial. Acta Med Iran. 2015;53(2):97–103.
  • Mohamed MA, Abdelmonem AM, Abdellah MA, et al. Oral hypoglycemic as attractive alternative to insulin for the management of diabetes mellitus during pregnancy. Gynecol Obstet (Sunnyvale). 2014;4:193.
  • Nachum Z, Ben-Shlomo I, Weiner E, et al. Twice daily versus four times daily insulin dose regimens for diabetes in pregnancy: randomized controlled trial. BMJ. 1999;319(7219):1223–1227.
  • Nor Azlin MI, Nor NA, Sufian SS, et al. Comparative study of two insulin regimes in pregnancy complicated by diabetes mellitus. Acta Obstet Gynecol Scand. 2007;86(4):407–408.
  • Persson B, Swahn ML, Hjertberg R, et al. Insulin lispro therapy in pregnancies complicated by type 1 diabetes mellitus. Diabetes Res Clin Pract. 2002;58(2):115–121.
  • Pettitt DJ, Ospina P, Howard C, et al. Efficacy, safety and lack of immunogenicity of insulin aspart compared with regular human insulin for women with gestational diabetes mellitus. Diabet Med. 2007;24(10):1129–1135.
  • O’Sullivan JB, Gellis SS, Tenney BO. Gestational blood glucose levels in normal and potentially diabetic women related to the birth weight of their infants. Diabetes. 1966;15(7):466–470.
  • Refuerzo JS, Gowen R, Pedroza C, et al. A pilot randomized, controlled trial of metformin versus insulin in women with type 2 diabetes mellitus during pregnancy. Am J Perinatol. 2015;30(2):163–170.
  • Rowan JA, Hague WM, Gao W, et al. Metformin versus insulin for the treatment of gestational diabetes. N Engl J Med. 2008;358(19):2003–2015.
  • Saleh HS, Abdelsalam WA, Mowafy HE, et al. Could metformin manage gestational diabetes mellitus instead of insulin? Int J Reprod Med. 2016;2016:3480629.
  • Ashoush S, El-Said M, Fathi H, et al. Identification of metformin poor responders, requiring supplemental insulin, during randomization of metformin versus insulin for the control of gestational diabetes mellitus. J Obstet Gynaecol Res. 2016;42(6):640–647.
  • Silva JC, Bertini AM, Taborda W, et al. Glibenclamide in the treatment for gestational diabetes mellitus in a compared study to insulin. Arq Bras Endocrinol Metabol. 2007;51(4):541–546.
  • Silva JC, Fachin DR, Coral ML, et al. Perinatal impact of the use of metformin and glyburide for the treatment of gestational diabetes mellitus. J Perinat Med. 2012;40(3):225–228.
  • Tempe A, Mayanglambam RD. Glyburide as treatment option for gestational diabetes mellitus. J Obstet Gynaecol Res. 2013;39(6):1147–1152.
  • Tertti K, Ekblad U, Koskinen P, et al. Metformin vs. insulin in gestational diabetes. A randomized study characterizing metformin patients needing additional insulin. Diabetes Obes Metab. 2013;15(3):246–251.
  • Thompson DJ, Porter KB, Gunnells DJ, et al. Prophylactic insulin in the management of gestational diabetes. Obstet Gynecol. 1990;75(6):960–964.
  • Waheed S, Malik FP, Mazhar SB. Efficacy of metformin versus insulin in the management of pregnancy with diabetes. J Coll Physicians Surg Pak. 2013;23(12):866–869.
  • Committee on Practice Bulletins—Obstetrics. Gestational diabetes mellitus. Practice Bulletin No. 137 American College of Obstetricians and Gynecologists. Obstet Gynecol. 2013;122(2):406–416.
  • International Diabetes Federation, Atlas I. 7th ed. Brussels: International Diabetes Federation; 2015.
  • Hod M, Kapur A, Sacks DA, et al. The International Federation of Gynecology and Obstetrics (FIGO) initiative on gestational diabetes mellitus: a pragmatic guide for diagnosis, management, and care. Int J Gynecol Obstet. 2015;131(Suppl 3):S173–S211.
  • Higgins JPT, Green S, editors. Cochrane handbook for systematic reviews of interventions, version 5.1.0 (update March 2011). The Cochrane Collaboration; 2011 [cited 2016 Nov 20]. Available from: www.cochrane-handbook.org
  • Borenstein M, Higgins JP, Hedges LV, et al. Basics of meta-analysis: I2 is not an absolute measure of heterogeneity. Res Synth Methods. 2017;8(1):5–18.
  • Moher D, Liberati A, Tetzlaff J, et al. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. J Clin Epidemiol. 2009;62(10):1006–1012.
  • Magro-Malosso ER, Saccone G, Chen M, et al. Induction of labour for suspected macrosomia at term in non-diabetic women: a systematic review and meta-analysis of randomized controlled trials. BJOG. 2017;124(3):414–421.
  • Maruotti GM, Saccone G, Martinelli P. Third trimester ultrasound soft-tissue measurements accurately predicts macrosomia. J Matern Fetal Neonatal Med. 2017;30(8):972–976.
  • Magro-Malosso ER, Saccone G, Di Mascio D, et al. Exercise during pregnancy and risk of preterm birth in overweight and obese women: a systematic review and meta-analysis of randomized controlled trials. Acta Obstet Gynecol Scand. 2017;96(3):263–273.
  • Rappa C, Saccone G. Recurrence of vaginal prolapse after total vaginal hysterectomy with concurrent vaginal uterosacral ligament suspension: comparison between normal-weight and overweight women. Am J Obstet Gynecol. 2016;215(5):601.e1–601.e4.
  • Di Mascio D, Magro-Malosso ER, Saccone G, et al. Exercise during pregnancy in normal-weight women and risk of preterm birth: a systematic review and meta-analysis of randomized controlled trials. Am J Obstet Gynecol. 2016;215(5):561–571.
  • Caissutti C, Khalifeh A, Saccone G, et al. Are women positive for the one step but negative for the two step screening tests for gestational diabetes at higher risk for adverse outcomes? Acta Obstet Gynecol Scand. 2018;97(2):122–134.
  • Caissutti C, Saccone G, Ciardulli A, et al. Very tight versus tight control: which should be the criteria for pharmacologic therapy dose adjustment in diabetes in pregnancy? Evidence from randomized controlled trials. Acta Obstet Gynecol Scand. 2018;97:235–247.
  • Saccone G, Caissutti C, Khalifeh A, et al. One Step versus Two Step approach for gestational diabetes screening: systematic review and meta-analysis of the randomized trials. J Matern Fetal Neonatal Med. 2017 Dec 3:1–9.
  • Brown J, Grzeskowiak L, Williamson K, et al. Insulin for the treatment of women with gestational diabetes. Cochrane Database Syst Rev. 2017;11:CD012037.
  • American Diabetes Association. Medical management of pregnancy complicated by diabetes. 3rd ed. Alexandria (VA): ADA; 2000.
  • American Diabetes Association. Nutrition recommendations and interventions for diabetes: a position statement of the American Diabetes Association. Diabetes Care 2008;31:(Suppl 1):S61–S78.
  • Cheung NW. The management of gestational diabetes: a review article. Vasc health risk Manag. 2009;5:153–164.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.