Effects of maternal folic acid supplementation on airway remodeling and allergic airway disease development

References

• Stover PJ. One-carbon metabolism–genome interactions in folate-associated pathologies. J Nutr. 2009;139(12):2402–2405.
   PubMed Web of Science ®Google Scholar
• De-Regil LM, Peña-Rosas JP, Fernández-Gaxiola AC, et al. Effects and safety of periconceptional oral folate supplementation for preventing birth defects. Cochrane Database Syst Rev. 2015;14(12):CD007950.
   Google Scholar
• US Preventive Services Task Force, Bibbins-Domingo K, Grossman DC, et al. folic acid supplementation for the prevention of neural tube defects: US Preventive Services Task Force Recommendation Statement. JAMA. 2017;317(2):183–189.
   PubMed Web of Science ®Google Scholar
• Bortolus R, Blom F, Filippini F, et al. Italian and Dutch folic acid trial study groups. Prevention of congenital malformations and other adverse pregnancy outcomes with 4.0 mg of folic acid: community-based randomized clinical trial in Italy and the Netherlands. BMC Pregnancy Childbirth. 2014;14:166.
   PubMed Web of Science ®Google Scholar
• McStay CL, Prescott SL, Bower C, et al. Maternal folic acid supplementation during pregnancy and childhood allergic disease outcomes: a question of timing? Nutrients. 2017;9(2):E123.
   PubMed Web of Science ®Google Scholar
• Hollingsworth JW, Maruoka S, Boon K, et al. In utero supplementation with methyl donors enhances allergic airway disease in mice. J Clin Invest. 2008;118(10):3462–3469.
   PubMed Web of Science ®Google Scholar
• Håberg SE, London SJ, Stigum H, et al. Folic acid supplements in pregnancy and early childhood respiratory health. Arch Dis Child. 2009;94(3):180–184.
   PubMed Web of Science ®Google Scholar
• Håberg SE, London SJ, Nafstad P, et al. Maternal folate levels in pregnancy and asthma in children at age 3 years. J Allergy Clin Immunol. 2011;127(1):262–4*, 264.e1.
   PubMed Web of Science ®Google Scholar
• Whitrow MJ, Moore VM, Rumbold AR, et al. Effect of supplemental folic acid in pregnancy on childhood asthma: a prospective birth cohort study. Am J Epidemiol. 2009;170(12):1486–1493.
   PubMed Web of Science ®Google Scholar
• National Research Council. Nutrient requirements of the mouse. In: Nutrient requirements of Laboratory Animals. 4th revised ed. Washington (DC): National Academy Press; 1995. p. 80–102.
   Google Scholar
• Shin IS, Lee MY, Cho ES, et al. Effects of maternal exposure to di(2-ethylhexyl)phthalate (DEHP) during pregnancy on susceptibility to neonatal asthma. Toxicol Appl Pharmacol. 2014;274(3):402–407.
   PubMed Web of Science ®Google Scholar
• Altınsoy C, Tuzun F, Duman N, et al. Effect of induced hypothermia on lipopolysaccharide-induced lung injury in neonatal rats. J Matern Fetal Neonatal Med. 2014;27(4):421–429.
   PubMed Web of Science ®Google Scholar
• Waterland RA, Travisano M, Tahiliani KG. Diet-induced hypermethylation at agouti viable yellow is not inherited transgenerationally through the female. FASEB J. 2007;21(12):3380–3385.
   PubMed Web of Science ®Google Scholar
• Shin HJ, Park HY, Jeong SJ, et al. STAT4 Expression in human T cells is regulated by DNA methylation but not by promoter polymorphism. J Immunol. 2005;175(11):7143–7150.
   PubMed Web of Science ®Google Scholar
• Kim HP, Leonard WJ. CREB/ATF-dependent T cell receptor-induced FoxP3 gene expression: a role for DNA methylation. J Exp Med. 2007;204(7):1543–1551.
   PubMed Web of Science ®Google Scholar
• Polansky JK, Kretschmer K, Freyer J, et al. DNA methylation controls Foxp3 gene expression. Eur J Immunol. 2008;38(6):1654–1663.
   PubMed Web of Science ®Google Scholar
• Siddiqui S, Martin JG. Structural aspects of airway remodelling in asthma. Curr Allergy Asthma Rep. 2008;8(6):540–547.
   PubMed Web of Science ®Google Scholar
• Meyer N, Akdis CA. Vascular endothelial growth factor as a key inducer of angiogenesis in the asthmatic airways. Curr Allergy Asthma Rep. 2013;13(1):1–9.
   PubMed Web of Science ®Google Scholar
• Halwani R, Al-Muhsen S, Al-Jahdali H, et al. Role of transforming growth factor-β in airway remodelling in asthma. Am J Respir Cell Mol Biol. 2011;44(2):127–133.
   PubMed Web of Science ®Google Scholar
• Grzela K, Litwiniuk M, Zagorska W, et al. Airway remodeling in chronic obstructive pulmonary disease and asthma: the role of matrix metalloproteinase-9. Arch Immunol Ther Exp (Warsz). 2016;64(1):47–55.
   PubMed Web of Science ®Google Scholar
• Heid MK, Bills ND, Hinrichs SH, et al. Folate deficiency alone does not produce neural tube defects in mice. J Nutr. 1992;122(4):888–894.
   PubMed Web of Science ®Google Scholar
• Pickell L, Brown K, Li D, et al. High intake of folic acid disrupts embryonic development in mice. Birth Defects Res: A Clin Mol Teratol. 2011;91(1):8–19.
   PubMed Web of Science ®Google Scholar
• Pickell L, Li D, Brown K, et al. Methylenetetrahydrofo-late reductase deficiency and low dietary folate increase embryonic delay and placental abnormalities in mice. Birth Defects Res A Clin Mol Teratol. 2009;85(6):531–541.
   PubMed Web of Science ®Google Scholar
• Mikael LG, Deng L, Paul L, et al. Moderately high intake of folic acid has a negative impact on mouse embryonic development. Birth Defects Res A Clin Mol Teratol. 2013;97(1):47–52.
   PubMed Web of Science ®Google Scholar
• Hollingsworth JW, Maruoka S, Boon K, et al. In utero supplementation with methyl donors enhances allergic airway disease in mice. J Clin Invest. 2016;126(5):2012.
   PubMed Web of Science ®Google Scholar
• Magdelijns FJ, Mommers M, Penders J, et al. Folic acid use in pregnancy and the development of atopy, asthma, and lung function in childhood. Pediatrics. 2011;128(1):e135–e144.
   PubMed Web of Science ®Google Scholar
• Crider KS, Cordero AM, Qi YP, et al. Prenatal folic acid and risk of asthma in children: a systematic review and meta-analysis. Am J Clin Nutr. 2013;98(5):1272–1281.
   PubMed Web of Science ®Google Scholar
• Wang T, Zhang HP, Zhang X, et al. Is folate status a risk factor for asthma or other allergic disease? Allergy Asthma Immunol Res. 2015;7(6):538–546.
   PubMed Web of Science ®Google Scholar