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Original Articles

Measuring fetal thymus size: a new method for diabetes screening in pregnancy

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Pages 1157-1161 | Received 07 Feb 2018, Accepted 26 Aug 2018, Published online: 25 Sep 2018

References

  • Zalel Y, Gamzu R, Mashiach S, et al. The development of the fetal thymus: an in utero sonographic evaluation. Prenat Diagn. 2002;22:114–117.
  • Ciofani M, Zúñiga-Pflücker JC. The thymus as an inductive site for T lymphopoiesis. Annu Rev Cell Dev Biol. 2007;23:463–493.
  • Varga I, Pospisilova V, Jablonska-Mestanova V, et al. The thymus: picture review of human thymus prenatal development. Bratisl Lek Listy. 2011;112:368–376.
  • Bodey B, Bodey B Jr., Siegel SE, et al. Involution of the mammalian thymus, one of the leading regulators of aging. In Vivo. 1997;11:421–440.
  • Goya RG, Bolognani F. Homeostasis, thymic hormones and aging. Gerontology. 1999;45:174–178.
  • Schuurman HJ, Kuper CF, Vos JG. Histopathology of the immune system as a tool to assess immunotoxicity. Toxicology. 1994;86:187–212.
  • Barker DJ, Winter PD, Osmond C, et al. Weight in infancy and death from ischaemic heart disease. Lancet. 1989;2:577–580.
  • Hales CN, Barker DJ. Type 2 (non-insulin-dependent) diabetes mellitus: the thrifty phenotype hypothesis. Diabetologia. 1992;35:595–601.
  • Chaoui R, Heling KS, Lopez AS, et al. The thymic-thoracic ratio in fetal heart defects: a simple way to identify fetuses at high risk for microdeletion 22q11. Ultrasound Obstet Gynecol. 2011;37:397–403.
  • Olearo E, Oberto M, Oggè G, et al. Thymic volume in healthy, small for gestational age and growth restricted fetuses. Prenat Diagn. 2012;32:662–667.
  • Cromi A, Ghezzi F, Raffaelli R, et al. Ultrasonographic measurement of thymus size in IUGR fetuses:a marker of the fetal immunoendocrine response to malnutrition. Ultrasound Obstet Gynecol. 2009;33:421–426.
  • Mohamed N, Eviston DP, Quinton AE, et al. Smaller fetal thymuses in pre-eclampsia: a prospective cross-sectional study. Ultrasound Obstet Gynecol. 2011;37:410–415.
  • Yinon Y, Zalel Y, Weisz B, et al. Fetal thymus size as a predictor of chorioamnionitis in women with preterm premature rupture of membranes. Ultrasound Obstet Gynecol. 2007;29:639–643.
  • Karl K, Heling KS, Sarut Lopez A, et al. Thymic–thoracic ratio in fetuses with trisomy 21, 18 or 13. Ultrasound Obstet Gynecol. 2012;40:412–417.
  • NSF Diabetes. Standards. Clinical care of children and young people with diabetes. Health Service Circular (HSC 2001/026). Dept. of Health 2001.
  • HAPO Study Cooperative Research Group, Metzger BE, Lowe LP, et al. Hyperglycemia and adverse pregnancy outcomes. N Engl J Med. 2008;358:1991–2002.
  • Wood SL, Jick H, Sauve R. The risk of stillbirth in pregnancies before and after the onset of diabetes. Diabet Med. 2003;20:703–707.
  • Yajnik CS. Fetal programming of diabetes: still so much to learn!. Diabetes Care. 2010;33:1146–1148.
  • Cho JY, Min JY, Lee YH, et al. Diameter of the normal fetal thymus on ultrasound. Ultrasound Obstet Gynecol. 2007;29:634–638.
  • Musilova I, Kacerovsky M, Reslova T, et al. Ultrasound measurements of the transverse diameter of the fetal thymus in uncomplicated singleton pregnancies. Neuro Endocrinol Lett. 2010;31:766–770.
  • Borgelt JM, Möllers M, Falkenberg MK, et al. Assessment of first-trimester thymus size and correlation with maternal diseases and fetal outcome. Acta Obstet Gynecol Scand. 2016;95:210–216.
  • Dörnemann R, Koch R, Möllmann U, et al. Fetal thymus size in pregnant women with diabetic diseases. J Perinat Med. 2017;45:595–601.
  • Gur EB, Gur MS, Ince O, et al. Vitamin D deficiency in pregnancy may affect fetal thymus development. Ginekol Pol. 2016;87:378–383.
  • Edwards A, Springett A, Padfield J, et al. Differences in post-mortem findings after stillbirth in women with and without diabetes. Diabet Med. 2013;30:1219–1224.
  • Desoye G, Nolan CJ. The fetal glucose steal: an underappreciated phenomenon in diabetic pregnancy. Diabetologia. 2016;59:1089–1094.
  • Eviston DP, Quinton AE, Benzie RJ, et al. Impaired fetal thymic growth precedes clinical preeclampsia: a case-control study. J Reprod Immunol. 2012;94:183–189.

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