Association between maternal/newborn genetic variants, placental pathology and spontaneous preterm birth risk: a Romanian population-based study

References

• Blencowe H, Cousens S, Chou D, et al. Born too soon: the global epidemiology of 15 million preterm births. Reprod Health. 2013 Nov;10(1):S2.
   PubMed Web of Science ®Google Scholar
• Hug L. ES et al. YD. Global, regional, and national levels and trends in under-5 mortality between 1990 and 2015, with scenario-based projections to 2030: a systematic analysis by the UN Inter-Agency Group for Child Mortality Estimation (vol 386, pg 2275, 2015). Lancet. 2015;386(1001 0):2256.
   Google Scholar
• Iams JD. Clinical practice. Prevention of preterm parturition. N Engl J Med. 2014;370(3):254–261.
   PubMed Web of Science ®Google Scholar
• Parets SE, Knight AK, Smith AK. Insights into genetic susceptibility in the etiology of spontaneous preterm birth. Appl Clin Genet. 2015;8:283–290.
   PubMedGoogle Scholar
• Esplin MS, O’Brien E, Fraser A, et al. Estimating recurrence of spontaneous preterm delivery. Obstet Gynecol. 2008;112(3):516–523.
   PubMed Web of Science ®Google Scholar
• Manuck TA. Racial and ethnic differences in preterm birth: a complex, multifactorial problem. Semin Perinatol. 2017;41(8):511–518.
   PubMed Web of Science ®Google Scholar
• York TP, Eaves LJ, Lichtenstein P, et al. Fetal and maternal genes’ influence on gestational age in a quantitative genetic analysis of 244,000 Swedish births. Am J Epidemiol. 2013;178(4):543–550.
   PubMed Web of Science ®Google Scholar
• Romero R, Dey SK, Fisher SJ. Preterm labor: one syndrome, many causes. Science. 2014;345(6198):760–765.
   PubMed Web of Science ®Google Scholar
• Kelly R, Holzman C, Senagore P, et al. Placental vascular pathology findings and pathways to preterm delivery. Am J Epidemiol. 2009;170(2):148–158.
   PubMed Web of Science ®Google Scholar
• Arias F, Rodriquez L, Rayne SC, et al. Maternal placental vasculopathy and infection: two distinct subgroups among patients with preterm labor and preterm ruptured membranes. Am J Obstet Gynecol. 1993;168(2):585–591.
   PubMed Web of Science ®Google Scholar
• Chaiworapongsa T, Romero R, Tarca A, et al. A subset of patients destined to develop spontaneous preterm labor has an abnormal angiogenic/anti-angiogenic profile in maternal plasma: evidence in support of pathophysiologic heterogeneity of preterm labor derived from a longitudinal study. J Matern Fetal Neonatal Med. 2009;22(12):1122–1139.
   PubMed Web of Science ®Google Scholar
• Dolan SM, Hollegaard MV, Merialdi M, et al. Synopsis of preterm birth genetic association studies: the preterm birth genetics knowledge base (PTBGene). Public Health Genom. 2010;13(7–8):514–523.
   PubMed Web of Science ®Google Scholar
• Plunkett J, Muglia LJ. Genetic contributions to preterm birth: implications from epidemiological and genetic association studies. Ann Med. 2008;40(3):167–195.
   PubMed Web of Science ®Google Scholar
• Romero R, Velez Edwards DR, Kusanovic JP, et al.. Identification of fetal and maternal single nucleotide polymorphisms in candidate genes that predispose to spontaneous preterm labor with intact membranes. Am J Obstet Gynecol. 2010;202(5):431.e1–431.34.
   Web of Science ®Google Scholar
• Harper M, Zheng SL, Thom E, et al. Cytokine gene polymorphisms and length of gestation. Obstet Gynecol. 2011;117(1):125–130.
   PubMed Web of Science ®Google Scholar
• Wu W, Clark EAS, Stoddard GJ, et al. Effect of interleukin-6 polymorphism on risk of preterm birth within population strata: a meta-analysis. BMC Genet. 2013;14:30.
   PubMed Web of Science ®Google Scholar
• Frey HA, Stout MJ, Pearson LN, et al. Genetic variation associated with preterm birth in African-American women. Am J Obstet Gynecol. 2016;215(2):235.e1–235.e8.
   Web of Science ®Google Scholar
• Uzun A, Dewan AT, Istrail S, et al. Pathway-based genetic analysis of preterm birth. Genomics. 2013;101(3):163–170.
   PubMed Web of Science ®Google Scholar
• York TP, Strauss JF, Neale MC, et al. Racial differences in genetic and environmental risk to preterm birth. PLoS ONE. 2010;5(8):e12391.
   PubMed Web of Science ®Google Scholar
• Auguste P, Javerzat S, Bikfalvi A. Regulation of vascular development by fibroblast growth factors. Cell Tissue Res. 2003;314(1):157–166.
   PubMed Web of Science ®Google Scholar
• Lee SH, Schloss DJ, Swain JL. Maintenance of vascular integrity in the embryo requires signaling through the fibroblast growth factor receptor. J Biol Chem. 2000;275(43):33679–33687.
   PubMed Web of Science ®Google Scholar
• Romero R, Espinoza J, Gonçalves LF, et al. The role of inflammation and infection in preterm birth. Semin Reprod Med. 2007;25(1):21–39.
   PubMed Web of Science ®Google Scholar
• Chaemsaithong P, Romero R, Korzeniewski SJ, et al. A rapid interleukin-6 bedside test for the identification of intra-amniotic inflammation in preterm labor with intact membranes. J Matern Fetal Neonatal Med. 2016;29(3):349–359.
   PubMed Web of Science ®Google Scholar
• Velez DR, Fortunato SJ, Williams SM, et al. Interleukin-6 (IL-6) and receptor (IL6-R) gene haplotypes associate with amniotic fluid protein concentrations in preterm birth. Hum Mol Genet. 2008;17(11):1619–1630.
   PubMed Web of Science ®Google Scholar
• Tency I, Verstraelen H, Kroes I, et al. Imbalances between matrix metalloproteinases (MMPs) and tissue inhibitor of metalloproteinases (TIMPs) in maternal serum during preterm labor. PLoS ONE. 2012;7(11):e49042.
   PubMed Web of Science ®Google Scholar
• Maymon E, Romero R, Pacora P, et al. A role for the 72 kDa gelatinase (MMP-2) and its inhibitor (TIMP-2) in human parturition, premature rupture of membranes and intraamniotic infection. J Perinat Med. 2001;29(4):308–316.
   PubMed Web of Science ®Google Scholar
• Rood KM, Buhimschi CS. Genetics, hormonal influences, and preterm birth. Semin Perinatol. 2017;41(7):401–408.
   PubMed Web of Science ®Google Scholar
• Glover AV, Manuck TA. Screening for spontaneous preterm birth and resultant therapies to reduce neonatal morbidity and mortality: a review. Semin Fetal Neonat Med. 2018;23(2):126–132.
   PubMed Web of Science ®Google Scholar
• Orsi NM, Gopichandran N, Simpson NAB. Genetics of preterm labour. Best Pract Res Clin Obstet Gynaecol. 2007;21(5):757–772.
   PubMed Web of Science ®Google Scholar
• York TP, Eaves LJ, Neale MC, et al. The contribution of genetic and environmental factors to the duration of pregnancy. Am J Obstet Gynecol. 2014;210(5):398–405.
   PubMed Web of Science ®Google Scholar
• Sebire NJ. Implications of placental pathology for disease mechanisms; methods, issues and future approaches. Placenta. 2017;52:122–126.
   PubMed Web of Science ®Google Scholar
• Morgan TK, Tolosa JE, Mele L, et al. Placental villous hypermaturation is associated with idiopathic preterm birth. J Matern Fetal Neonatal Med. 2013;26(7):647–653.
   PubMed Web of Science ®Google Scholar
• Redline RW. The clinical implications of placental diagnoses. Semin Perinatol. 2015;39(1):2–8.
   PubMed Web of Science ®Google Scholar
• Parks WT. Placental hypoxia: the lesions of maternal malperfusion. Semin Perinatol. 2015;39(1):9–19.
   PubMed Web of Science ®Google Scholar
• Hendler I, Goldenberg RL, Mercer BM, et al. The preterm prediction study: association between maternal body mass index and spontaneous and indicated preterm birth. Am J Obstet Gynecol. 2005;192(3):882–886.
   PubMed Web of Science ®Google Scholar
• Catov JM, Scifres CM, Caritis SN, et al. Neonatal outcomes following preterm birth classified according to placental features. Am J Obstet Gynecol. 2017;216(4):411.e1–411.e14.
   Web of Science ®Google Scholar
• Brosens I, Pijnenborg R, Vercruysse L, et al. The “great obstetrical syndromes” are associated with disorders of deep placentation. Am J Obstet Gynecol. 2011;204(3):193–201.
   PubMed Web of Science ®Google Scholar
• Taylor RN, Grimwood J, Taylor RS, et al. Longitudinal serum concentrations of placental growth factor: evidence for abnormal placental angiogenesis in pathologic pregnancies. Am J Obstet Gynecol. 2003;188(1):177–182.
   PubMed Web of Science ®Google Scholar
• Savasan ZA, Romero R, Chaiworapongsa T, et al. Evidence in support of a role for anti-angiogenic factors in preterm prelabor rupture of membranes. J Matern Fetal Neonatal Med. 2010;23(8):828–841.
   PubMed Web of Science ®Google Scholar
• Manuck TA, Esplin MS, Biggio J, et al. The phenotype of spontaneous preterm birth: application of a clinical phenotyping tool. Am J Obstet Gynecol. 2015;212(4):487.e1–487.e11.
   PubMed Web of Science ®Google Scholar