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Original Articles

Does severe vitamin D deficiency impact obstetric outcomes in pregnant women with thyroid autoimmunity?

ORCID Icon & ORCID Icon
Pages 1359-1369 | Received 20 Apr 2018, Accepted 30 Aug 2018, Published online: 25 Sep 2018

References

  • McLeod DS, Cooper DS. The incidence and prevalence of thyroid autoimmunity. Endocrine. 2012;42(2):252–265.
  • Fish EN. The X-Files in immunity: sex-based differences predispose immune responses. Nat Rev Immunol. 2008;8(9):737–744.
  • Alexander EK, Pearce EN, Brent GA, et al. 2017 Guidelines of the American Thyroid Association for the diagnosis and management of thyroid disease during pregnancy and the postpartum. Thyroid. 2017;27(3):315–389.
  • Cantorna MT, Mahon BD. Mounting evidence for vitamin D as an environmental factor affecting autoimmune disease prevalence. Exp Biol Med. 2004;229(11):1136–1142.
  • Xu MY, Cao B, Yin J, et al. Vitamin D and Graves’ disease: a meta-analysis update. Nutrients. 2015;7(5):3813–3827.
  • Baeke F, Takiishi T, Korf H, et al. Vitamin D: modulator of the immune system. Curr Opin Pharmacol. 2010;10(4):482–496.
  • Turhan Iyidir O, Konca Degertekin C, Sonmez C, et al. The effect of thyroid autoimmunity on T-cell responses in early pregnancy. J Reprod Immunol. 2015;110:61–66.
  • Liu NQ, Kaplan AT, Lagishetty V, et al. Vitamin D and the regulation of placental inflammation. J Immunol. 2011;186(10):5968–5974.
  • Amegah AK, Klevor MK, Wagner CL. Maternal vitamin D insufficiency and risk of adverse pregnancy and birth outcomes: a systematic review and meta-analysis of longitudinal studies. PLoS One. 2017;12(3):e0173605.
  • Merewood A, Mehta SD, Chen TC, et al. Association between vitamin D deficiency and Primary Cesarean Section. J Clin Endocrinol Metab. 2009;94(3):940–945.
  • Yılmaz B, Aygün C, Çetinoğlu E. Vitamin D levels in newborns and association with neonatal hypocalcemia. J Matern Fetal Neonatal Med. 2018;31(14):1889–1893.
  • Kivity S, Agmon-Levin N, Zisappl M, et al. Vitamin D and autoimmune thyroid diseases. Cell Mol Immunol. 2011;8(3):243–247.
  • Tamer G, Arik S, Tamer I, et al. Relative vitamin D insufficiency in Hashimoto’s thyroiditis. Thyroid. 2011;21(8):891–896.
  • Bozkurt NC, Karbek B, Ucan B, et al. The association between severity of vitamin D deficiency and Hashimoto’s thyroiditis. Endocr Pract. 2013;19(3):479–484.
  • Aydogmus S, Kelekci S, Aydogmus H, et al. High prevalence of vitamin D deficiency among pregnant women in a Turkish population and impact on perinatal outcomes. J Matern Fetal Neonatal Med. 2015;28(15):1828–1832.
  • Ates S, Sevket O, Ozcan P, et al. Vitamin D status in the first-trimester: effects of vitamin D deficiency on pregnancy outcomes. Afr Health Sci. 2016;16(1):36–43.
  • Holick MF, Binkley NC, Bischoff-Ferrari HA, et al. Evaluation, treatment, and prevention of vitamin D deficiency: an endocrine society clinical practice guideline. J Clin Endocrinol Metab. 2011;96(7):1911–1930.
  • Bener A, Al-Hamaq AO, Saleh NM. Association between vitamin D insufficiency and adverse pregnancy outcome: global comparisons. Int J Womens Health. 2013;5:523–531.
  • American College of Obstetricians and Gynecologists. Practice Bulletin No. 148: thyroid disease in pregnancy. Obstet Gynecol. 2015;125(4):996–1005.
  • Zhang J, Merialdi M, Platt LD, et al. Defining normal and abnormal fetal growth: promises and challenges. Am J Obstet Gynecol. 2010;202(6):522–528.
  • American College of Obstetricians and Gynecologists’ Task Force on Hypertension in Pregnancy, Task Force on Hypertension in Pregnancy. Hypertension in pregnancy. Report of the American College of Obstetricians and Gynecologists’ Task Force on Hypertension in Pregnancy. Obstet Gynecol. 2013;122(5):1122–1131.
  • American College of Obstetricians and Gynecologists. ACOG Committee Opinion No. 579: definition of term pregnancy. Obstet Gynecol. 2013;122(5):1139–1140.
  • American College of Obstetricians and Gynecologists. ACOG Practice bulletin No. 188: prelabor rupture of membranes. Obstet Gynecol. 2018;131(1):e1–e14.
  • American College of Obstetricians and Gynecologists. Practice Bulletin No. 137: gestational diabetes mellitus. Obstet Gynecol. 2013;122(Pt 1):406–416.
  • Moon HW, Chung HJ, Hur M, et al. Vitamin D status and thyroid autoimmunity in Korean pregnant women. J Matern Fetal Neonatal Med. 2015;28(18):2210–2213.
  • Holick MF, Chen TC, Lu Z, et al. Vitamin D and skin physiology: a D-lightful story. J Bone Miner Res. 2007;22(Suppl 2):V28–V33.
  • Hewison M. An update on vitamin D and autoimmunity. Clin Endocrinol. 2012;76(3):315–325.
  • D’Aurizio F, Villalta D, Metus P, et al. Is vitamin D a player or not in the pathophysiology of autoimmune thyroid diseases? Autoimmun Rev. 2015;14(5):363–369.
  • Yoo WS, Chung HK. Recent advances in autoimmune thyroid diseases. Endocrinol Metab. 2016;31(3):379–385.
  • Prietl B, Treiber G, Pieber TR, et al. Vitamin D and immune function. Nutrients. 2013;5(7):2502–2521.
  • Shahbazi M, Jeddi-Tehrani M, Zareie M, et al. Expression profiling of vitamin D receptor in placenta, decidua and ovary of pregnant mice. Placenta. 2011;32(9):657–664.
  • Rudick B, Ingles S, Chung K, et al. Characterizing the influence of vitamin D levels on IVF outcomes. Hum Reprod. 2012;27(11):3321–3327.
  • Smith TA, Kirkpatrick DR, Kovilam O, et al. Immunomodulatory role of vitamin D in the pathogenesis of preeclampsia. Expert Rev Clin Immunol. 2015;11(9):1055–1063.
  • Maiya S, Sullivan I, Allgrove J, et al. Hypocalcemia and vitamin D deficiency: an important, but preventable, cause of life-threatening infant heart failure. Heart. 2008;94(5):581–584.
  • Pearce EN, Oken E, Gillman MW, et al. Association of first trimester thyroid function test values with thyroperoxidase antibody status, smoking, and multivitamin use. Endocr Pract. 2008;14(1):33–39.
  • Mehran L, Tohidi M, Sarvghadi F, et al. Management of thyroid peroxidase antibody euthyroid women in pregnancy: comparison of the American Thyroid Association and the endocrine society guidelines. J Thyroid Res. 2013;2013:542692.
  • Konova E. The role of NK cells in the autoimmune thyroid disease associated pregnancy loss. Clin Rev Allergy Immunol. 2010;39(3):176–184.
  • Challis JR, Lockwood CJ, Myatt L, et al. Inflammation and pregnancy. Reprod Sci. 2009;16(2):206–215.
  • Sullivan GM, Feinn R. Using effect size – or why the P value is not enough. J Grad Med Educ. 2012;4(3):279–282.
  • Catalano PM. Trying to understand gestational diabetes. Diabet Med. 2014;31(3):273–281.
  • Schober L, Radnai D, Spratte J, et al. The role of regulatory T cell (Treg) subsets in gestational diabetes mellitus. Clin Exp Immunol. 2014;177(1):76–85.
  • Bitterman O, Bongiovanni M, Giuliani C, et al. Anti thyroperoxidase and anti thyroglobulin antibodies in diabetic pregnancies. J Endocrinol Invest. 2014;37(10):911–915.
  • Ying H, Tang YP, Bao YR, et al. Maternal TSH level and TPOAb status in early pregnancy and their relationship to the risk of gestational diabetes mellitus. Endocrine. 2016;54(3):742–750.
  • Karakosta P, Alegakis D, Georgiou V, et al. Thyroid dysfunction and autoantibodies in early pregnancy are associated with increased risk of gestational diabetes and adverse birth outcomes. J Clin Endocrinol Metab. 2012;97(12):4464–4472.
  • Yang Y, Li Q, Wang Q, et al. Thyroid antibodies and gestational diabetes mellitus: a meta-analysis. Fertil Steril. 2015;104(3):665–71.e3.
  • Palomer X, González-Clemente JM, Blanco-Vaca F, et al. Role of vitamin D in the pathogenesis of type 2 diabetes mellitus. Diabetes Obes Metab. 2008;10(3):185–197.
  • Kramer CK, Swaminathan B, Hanley AJ, et al. Vitamin D and parathyroid hormone status in pregnancy: effect on insulin sensitivity, β- cell function, and gestational diabetes mellitus. J Clin Endocrinol Metab. 2014;99(12):4506–4513.
  • Wang O, Nie M, Hu YY, et al. Association between vitamin D insufficiency and the risk for gestational diabetes mellitus in pregnant Chinese women. Biomed Environ Sci. 2012;25(4):399–406.
  • Soheilykhah S, Mojibian M, Moghadam MJ, et al. The effect of different doses of vitamin D supplementation on insulin resistance during pregnancy. Gynecol Endocrinol. 2013;29(4):396–399.
  • Abbassi-Ghanavati M, Casey BM, Spong CY, et al. Pregnancy outcomes in women with thyroid peroxidase antibodies. Obstet Gynecol. 2010;116(Pt 1):381–386.
  • Negro R, Formoso G, Mangieri T, et al. Levothyroxine treatment in euthyroid pregnant women with autoimmune thyroid disease: effects on obstetrical complications. J Clin Endocrinol Metab. 2006;91(7):2587–2591.
  • Guleria I, Sayegh MH. Maternal acceptance of the fetus: true human tolerance. J Immunol. 2007;178(6):3345–3351.

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