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Original Articles

Fetal neuroprotective mechanism of maternal magnesium sulfate for late gestation inflammation: in a rodent model

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Pages 3732-3739 | Received 23 Oct 2018, Accepted 13 Feb 2019, Published online: 05 Mar 2019

References

  • Yoon BH, Park CW, Chaiworapongsa T. Intrauterine infection and the development of cerebral palsy. BJOG. 2003;110(Suppl 20):124–127.
  • Spinillo A, Capuzzo E, Stronati M, et al. Obstetric risk factors for periventricular leukomalacia among preterm infants. Br J Obstet Gynaecol. 1998;105(8):865–871.
  • Polivka BJ, Nickel JT, Wilkins JR, 3rd. Urinary tract infection during pregnancy: a risk factor for cerebral palsy? J Obstet Gynecol Neonat Nurs. 1997;26(4):405–413.
  • Sham PC, O’Callaghan E, Takei N, et al. Schizophrenia following pre-natal exposure to influenza epidemics between 1939 and 1960. Br J Psychiatry. 1992;160:461–466.
  • Mednick SA, Machon RA, Huttunen MO, et al. Adult schizophrenia following prenatal exposure to an influenza epidemic. Arch Gen Psychiatry. 1988;45(2):189–192.
  • Mattocks AR, Driver HE. Metabolism and toxicity of anacrotine, a pyrrolizidine alkaloid, in rats. Chem Biol Interact. 1987;63(1):91–104.
  • Brown AS, Begg MD, Gravenstein S, et al. Serologic evidence of prenatal influenza in the etiology of schizophrenia. Arch Gen Psychiatry. 2004;61(8):774–780.
  • Yamashita Y, Fujimoto C, Nakajima E, et al. Possible association between congenital cytomegalovirus infection and autistic disorder. J Autism Dev Disord. 2003;33(4):455–459.
  • Chess S. Follow-up report on autism in congenital rubella. J Autism Child Schizophr. 1977;7(1):69–81.
  • Atladóttir HO, Thorsen P, Østergaard L, et al. Maternal infection requiring hospitalization during pregnancy and autism spectrum disorders. J Autism Dev Disord. 2010;40(12):1423–1430.
  • Fatemi SH, Pearce DA, Brooks AI, et al. Prenatal viral infection in mouse causes differential expression of genes in brains of mouse progeny: a potential animal model for schizophrenia and autism. Synapse. 2005;57(2):91–99.
  • Beloosesky R, Ginsberg Y, Khatib N, et al. Prophylactic maternal N-acetylcysteine in rats prevents maternal inflammation-induced offspring cerebral injury shown on magnetic resonance imaging. Am J Obstet Gynecol. 2013;208(3):213.e1–213.e6.
  • Gayle DA, Beloosesky R, Desai M, et al. Maternal LPS induces cytokines in the amniotic fluid and corticotropin releasing hormone in the fetal rat brain. Am J Physiol Regul Integr Comp Physiol. 2004;286(6):R1024–R1029.
  • Gray PH, Jones P, O’Callaghan MJ. Maternal antecedents for cerebral palsy in extremely preterm babies: a case–control study. Dev Med Child Neurol. 2001;43(9):580–585.
  • Yoon BH, Romero R, Kim CJ, et al. High expression of tumor necrosis factor-alpha and interleukin-6 in periventricular leukomalacia. Am J Obstet Gynecol. 1997;177(2):406–411.
  • Kadhim H, Tabarki B, De Prez C, et al. Cytokine immunoreactivity in cortical and subcortical neurons in periventricular leukomalacia: are cytokines implicated in neuronal dysfunction in cerebral palsy? Acta neuropathol. 2003;105(3):209–216.
  • Kadhim H, Tabarki B, De Prez C, et al. Interleukin-2 in the pathogenesis of perinatal white matter damage. Neurology. 2002;58(7):1125–1128.
  • Deguchi K, Mizuguchi M, Takashima S. Immunohistochemical expression of tumor necrosis factor alpha in neonatal leukomalacia. Pediatr Neurol. 1996;14(1):13–16.
  • Huang CY, Hsieh YL, Ju DT, et al. Attenuation of magnesium sulfate on CoCl-induced cell death by activating ERK1/2/MAPK and inhibiting HIF-1α via mitochondrial apoptotic signaling suppression in a neuronal cell line. Chin J Physiol. 2015;58(4):244–253.
  • Sameshima H, Ikenoue T. Effect of long-term, postasphyxial administration of magnesium sulfate on immunostaining of microtubule-associated protein-2 and activated caspase-3 in 7-day-old rat brain. J Soc Gynecol Investig. 2002;9(4):203–209.
  • Cetinkaya M, Alkan T, Ozyener F, et al. Possible neuroprotective effects of magnesium sulfate and melatonin as both pre- and post-treatment in a neonatal hypoxic-ischemic rat model. Neonatology. 2011;99(4):302–310.
  • Hoesel B, Schmid JA. The complexity of NF-κB signaling in inflammation and cancer. Mol Cancer. 2013;12:86.
  • Tam Tam HB, Dowling O, Xue X, et al. Magnesium sulfate ameliorates maternal and fetal inflammation in a rat model of maternal infection. Am J Obstet Gynecol. 2011;204(4):364.e1–364.e8.
  • Czikk MJ, McCarthy FP, Murphy KE. Chorioamnionitis: from pathogenesis to treatment. Clin Microbiol Infect. 2011;17(9):1304–1311.
  • Goñi-de-Cerio F, Alvarez A, Lara-Celador I, et al. Magnesium sulfate treatment decreases the initial brain damage alterations produced after perinatal asphyxia in fetal lambs. J Neurosci Res. 2012;90(10):1932–1940.
  • Hirtz DG, Weiner SJ, Bulas D, et al. Antenatal magnesium and cerebral palsy in preterm infants. J Pediatr. 2015;167(4):834–839.e3.
  • Gano D, Ho ML, Partridge JC, et al. Antenatal exposure to magnesium sulfate is associated with reduced cerebellar hemorrhage in preterm newborns. J Pediatr. 2016;178:68–74.
  • Suzuki-Kakisaka H, Sugimoto J, Tetarbe M, et al. Magnesium sulfate increases intracellular magnesium reducing inflammatory cytokine release in neonates. Am J Reprod Immunol. 2013;70(3):213–220.
  • Sugimoto J, Romani AM, Valentin-Torres AM, et al. Magnesium decreases inflammatory cytokine production: a novel innate immunomodulatory mechanism. J Immunol. 2012;188(12):6338–6346.
  • Huang CY, Liou YF, Chung SY, et al. Role of ERK signaling in the neuroprotective efficacy of magnesium sulfate treatment during focal cerebral ischemia in the gerbil cortex. Chin J Physiol. 2010;53(5):299–309.
  • Jacquemyn Y, Zecic A, Van Laere D, et al. The use of intravenous magnesium in non-preeclamptic pregnant women: fetal/neonatal neuroprotection. Arch Gynecol Obstet. 2015;291(5):969–975.
  • Gao F, Ding B, Zhou L, et al. Magnesium sulfate provides neuroprotection in lipopolysaccharide-activated primary microglia by inhibiting NF-κB pathway. J Surg Res. 2013;184(2):944–950.
  • Shih RH, Wang CY, Yang CM. NF-kappaB signaling pathways in neurological inflammation: a mini review. Front Mol Neurosci. 2015;8:77.
  • Burd I, Breen K, Friedman A, et al. Magnesium sulfate reduces inflammation-associated brain injury in fetal mice. Am J Obstet Gynecol. 2010;202(3):292.e1–292.e9.
  • Rice D, Barone S, Jr. Critical periods of vulnerability for the developing nervous system: evidence from humans and animal models. Environ Health Perspect. 2000;108(Suppl 3):511–533.
  • Semple BD, Blomgren K, Gimlin K, et al. Brain development in rodents and humans: identifying benchmarks of maturation and vulnerability to injury across species. Prog Neurobiol. 2013;106–107:1–16.
  • Erhardt S, Lim CK, Linderholm KR, et al. Connecting inflammation with glutamate agonism in suicidality. Neuropsychopharmacology. 2013;38(5):743–752.
  • Black SA, Stys PK, Zamponi GW, et al. Cellular prion protein and NMDA receptor modulation: protecting against excitotoxicity. Front Cell Dev Biol. 2014;2:45.
  • Magpie Trial Follow-Up Study Collaborative Group. The magpie Trial: a randomised trial comparing magnesium sulphate with placebo for pre-eclampsia. Outcome for children at 18 months. BJOG. 2007;114(3):289–299.

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