Advanced search
Publication Cover
The Journal of Maternal-Fetal & Neonatal Medicine Volume 34, 2021 - Issue 21
Submit an article Journal homepage
1,044
Views
27
CrossRef citations to date
0
Altmetric
Review Articles

Perinatal death by bile acid levels in intrahepatic cholestasis of pregnancy: a systematic review

Daniele Di Mascioa Department of Maternal and Child Health and Urological Sciences, “Sapienza” University of Rome, Rome, ItalyORCID Iconhttps://orcid.org/0000-0002-6560-3393
ORCID Icon,
Johanna Quist-Nelsonb Department of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine, Sidney Kimmel Medical College – Thomas Jefferson University, Philadelphia, PA, USA
,
Melissa Riegelb Department of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine, Sidney Kimmel Medical College – Thomas Jefferson University, Philadelphia, PA, USA
,
Brandon Georgec Jefferson College of Population Health, Thomas Jefferson University, Philadelphia, PA, USA
,
Gabriele Sacconed Department of Neuroscience, Reproductive Sciences and Dentistry, School of Medicine, University of Naples “Federico II”, Naples, ItalyORCID Iconhttps://orcid.org/0000-0003-0078-2113
ORCID Icon,
Romana Brune Division of Obstetrics, University Hospital Zurich, Zurich, Switzerland
,
Christian Haslingere Division of Obstetrics, University Hospital Zurich, Zurich, Switzerland
,
Christina Herreraf Department of Obstetrics and Gynecology, University of Utah, Salt Lake City, UT, USA;g Intermountain Healthcare Division of Maternal Fetal Medicine, Salt Lake City, UT, USA;h Division of Maternal Fetal Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
,
Tetsuya Kawakitai Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Medstar Washington Hospital Center, Washington, DC, USA
,
Richard H. Leej Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA
,
Pierluigi Benedetti Panicia Department of Maternal and Child Health and Urological Sciences, “Sapienza” University of Rome, Rome, Italy
&
Vincenzo Berghellab Department of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine, Sidney Kimmel Medical College – Thomas Jefferson University, Philadelphia, PA, USACorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0003-2854-0239
ORCID Icon show all
Pages 3614-3622 | Received 03 Jul 2019, Accepted 24 Oct 2019, Published online: 19 Nov 2019

References

  • Tran TT, Ahn J, Reau NS. ACG clinical guideline: liver disease and pregnancy. Am J Gastroenterol. 2016;111(2):176–194.
  • Royal College of Obstetricians and Gynaecologists. Obstetric cholestasis. Green-top guideline no. 43. London: Royal College of Obstetricians and Gynaecologists; 2011.
  • Diken Z, Usta IM, Nassar AH. A clinical approach to intrahepatic cholestasis of pregnancy. Am J Perinatol. 2014;31(1):1–8.
  • Glantz A, Marschall HU, Mattsson LA. Intrahepatic cholestasis of pregnancy: relationships between bile acid levels and fetal complication rates. Hepatology. 2004;40(2):467–474.
  • Brouwers L, Koster MP, Page-Christiaens GC, et al. Intrahepatic cholestasis of pregnancy: maternal and fetal outcomes associated with elevated bile acid levels. Am J Obstet Gynecol. 2015;212(1):100.e1–100.e7.
  • Kawakita T, Parikh LI, Ramsey PS, et al. Predictors of adverse neonatal outcomes in intrahepatic cholestasis of pregnancy. Am J Obstet Gynecol. 2015;213(4):570.e1–570.e8.
  • Geenes V, Lövgren-Sandblom A, Benthin L, et al. The reversed feto-maternal bile acid gradient in intrahepatic cholestasis of pregnancy is corrected by ursodeoxycholic acid. PLoS One. 2014;9(1):e83828.
  • Williamson C, Hems LM, Goulis DG, et al. Clinical outcome in a series of cases of obstetric cholestasis identified via a patient support group. BJOG. 2004;111(7):676–681.
  • Williamson C, Miragoli M, Sheikh Abdul Kadir S, et al. Bile acid signaling in fetal tissues: implications for intrahepatic cholestasis of pregnancy. Dig Dis. 2011;29(1):58–61.
  • Sepúlveda WH, González C, Cruz MA, et al. Vasoconstrictive effect of bile acids on isolated human placental chorionic veins. Eur J Obstet Gynecol Reprod Biol. 1991;42(3):211–215.
  • Geenes V, Chappell LC, Seed PT, et al. Association of severe intrahepatic cholestasis of pregnancy with adverse pregnancy outcomes: a prospective population-based case-control study. Hepatology. 2014;59(4):1482–1491.
  • Cui D, Zhong Y, Zhang L, et al. Bile acid levels and risk of adverse perinatal outcomes in intrahepatic cholestasis of pregnancy: a meta-analysis. J Obstet Gynaecol Res. 2017;43(9):1411–1420.
  • Ovadia C, Seed PT, Sklavounos A, et al. Association of adverse perinatal outcomes of intrahepatic cholestasis of pregnancy with biochemical markers: results of aggregate and individual patient data meta-analyses. Lancet. 2019;393(10174):899–909.
  • Higgins JPT, Altman DG ,Sterne JAC. 2001. Cochrane handbook for systematic reviews of interventions. The Cochrane Collaboration, version 5.1.0 [updated 2011 March; accessed 2015 Dec 20]. Available at www.cochrane-handbook.org
  • Wells GA, Shea B, O'Connell D et al. Newcastle-Ottawa Scale for assessing the quality of non randomised studies in meta-analyses. Available at www.ohri.ca/programs/clinical_epidemiology/oxford.asp
  • Moher D, Liberati A, Tetzlaff J, et al. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. J Clin Epidemiol. 2009;62(10):1006–1012.
  • Ambros-Rudolph CM, Glatz M, Trauner M, et al. The importance of serum bile acid level analysis and treatment with ursodeoxycholic acid in intrahepatic cholestasis of pregnancy: a case series from central Europe. Arch Dermatol. 2007;143(6):757–762.
  • Lee RH, Kwok KM, Ingles S, et al. Pregnancy outcomes during an era of aggressive management for intrahepatic cholestasis of pregnancy. Amer J Perinatol. 2008;25(6):341–345.
  • Furrer R, Winter K, Schäffer L, et al. Postpartum blood loss in women treated for intrahepatic cholestasis of pregnancy. Obstet Gynecol. 2016;128(5):1048–1052.
  • Herrera CA, Manuck TA, Stoddard GJ, et al. Perinatal outcomes associated with intrahepatic cholestasis of pregnancy. J Matern Fetal Neonatal Med. 2018;31(14):1913–1920.
  • Palmer KR, Xiaohua L, Mol BW. Management of intrahepatic cholestasis in pregnancy. Lancet. 2019;393(10174):853–854.
  • Oztekin D, Aydal I, Oztekin O, et al. Predicting fetal asphyxia in intrahepatic cholestasis of pregnancy. Arch Gynecol Obstet. 2009;280(6):975–979.
  • Puljic A, Kim E, Page J, et al. The risk of infant and fetal death by each additional week of expectant management in intrahepatic cholestasis of pregnancy by gestational age. Am J Obstet Gynecol. 2015;212(5):667.e1–667.e5.
  • Kong X, Kong Y, Zhang F, et al. Evaluating the effectiveness and safety of ursodeoxycholic acid in treatment of intrahepatic cholestasis of pregnancy: a meta-analysis (a prisma-compliant study). Medicine (Baltimore). 2016;95(40):e4949.
  • Gurung V, Middleton P, Milan SJ, et al. Interventions for treating cholestasis in pregnancy. Cochrane Database Syst Rev. 2013;6(6)CD000:493.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.